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Volumn 32, Issue 12, 2014, Pages 3209-3218

SNAI2 controls the undifferentiated state of human epidermal progenitor cells

Author keywords

ChIP Seq; Differentiation; Epidermal differentiation; Epidermis; Epithelial to mesenchymal transition; Epithelium; GRHL3; KLF4; Metastasis; Progenitor cell; Skin differentiation; SLUG; SNAI2; SNAIL; Stem cell; Transcription factor

Indexed keywords

TRANSCRIPTION FACTOR SLUG; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

EID: 84912080477     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1809     Document Type: Article
Times cited : (61)

References (37)
  • 1
    • 84873608154 scopus 로고    scopus 로고
    • Mechanisms that regulate stem cell aging and life span
    • Signer RA, Morrison SJ,. Mechanisms that regulate stem cell aging and life span. Cell Stem Cell 2013; 12: 152-165.
    • (2013) Cell Stem Cell , vol.12 , pp. 152-165
    • Signer, R.A.1    Morrison, S.J.2
  • 2
    • 33751230475 scopus 로고    scopus 로고
    • P63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • Truong AB, Kretz M, Ridky TW, et al. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev 2006; 20: 3185-3197.
    • (2006) Genes Dev , vol.20 , pp. 3185-3197
    • Truong, A.B.1    Kretz, M.2    Ridky, T.W.3
  • 3
    • 47549105128 scopus 로고    scopus 로고
    • Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3
    • Sen GL, Webster DE, Barragan DI, et al. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes Dev 2008; 22: 1865-1870.
    • (2008) Genes Dev , vol.22 , pp. 1865-1870
    • Sen, G.L.1    Webster, D.E.2    Barragan, D.I.3
  • 4
    • 33646429507 scopus 로고    scopus 로고
    • Epidermal barrier formation and recovery in skin disorders
    • Segre JA,. Epidermal barrier formation and recovery in skin disorders. J Clin Invest 2006; 116: 1150-1158.
    • (2006) J Clin Invest , vol.116 , pp. 1150-1158
    • Segre, J.A.1
  • 5
    • 75749104729 scopus 로고    scopus 로고
    • DNMT1 maintains progenitor function in self-renewing somatic tissue
    • Sen GL, Reuter JA, Webster DE, et al. DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature 2010; 463: 563-567.
    • (2010) Nature , vol.463 , pp. 563-567
    • Sen, G.L.1    Reuter, J.A.2    Webster, D.E.3
  • 6
    • 62149122634 scopus 로고    scopus 로고
    • Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells
    • Ezhkova E, Pasolli HA, Parker JS, et al. Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell 2009; 136: 1122-1135.
    • (2009) Cell , vol.136 , pp. 1122-1135
    • Ezhkova, E.1    Pasolli, H.A.2    Parker, J.S.3
  • 7
    • 84873595705 scopus 로고    scopus 로고
    • ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4
    • Bao X, Tang J, Lopez-Pajares V, et al. ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4. Cell Stem Cell 2013; 12: 193-203.
    • (2013) Cell Stem Cell , vol.12 , pp. 193-203
    • Bao, X.1    Tang, J.2    Lopez-Pajares, V.3
  • 8
    • 80052300618 scopus 로고    scopus 로고
    • Regulation of human epidermal stem cell proliferation and senescence requires polycomb- dependent and -independent functions of Cbx4
    • Luis NM, Morey L, Mejetta S, et al. Regulation of human epidermal stem cell proliferation and senescence requires polycomb- dependent and -independent functions of Cbx4. Cell Stem Cell 2011; 9: 233-246.
    • (2011) Cell Stem Cell , vol.9 , pp. 233-246
    • Luis, N.M.1    Morey, L.2    Mejetta, S.3
  • 9
    • 84863613835 scopus 로고    scopus 로고
    • Progenitor function in self-renewing human epidermis is maintained by the exosome
    • Mistry DS, Chen Y, Sen GL,. Progenitor function in self-renewing human epidermis is maintained by the exosome. Cell Stem Cell 2012; 11: 127-135.
    • (2012) Cell Stem Cell , vol.11 , pp. 127-135
    • Mistry, D.S.1    Chen, Y.2    Sen, G.L.3
  • 10
    • 84895887786 scopus 로고    scopus 로고
    • Loss of Grainy head-like 1 is associated with disruption of the epidermal barrier and squamous cell carcinoma of the skin
    • Mlacki M, Darido C, Jane SM, et al. Loss of Grainy head-like 1 is associated with disruption of the epidermal barrier and squamous cell carcinoma of the skin. PLoS One 2014; 9: e89247.
    • (2014) PLoS One , vol.9 , pp. e89247
    • Mlacki, M.1    Darido, C.2    Jane, S.M.3
  • 11
    • 0032813661 scopus 로고    scopus 로고
    • Klf4 is a transcription factor required for establishing the barrier function of the skin
    • Segre JA, Bauer C, Fuchs E,. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat Genet 1999; 22: 356-360.
    • (1999) Nat Genet , vol.22 , pp. 356-360
    • Segre, J.A.1    Bauer, C.2    Fuchs, E.3
  • 12
    • 20244389223 scopus 로고    scopus 로고
    • A homolog of Drosophila grainy head is essential for epidermal integrity in mice
    • Ting SB, Caddy J, Hislop N, et al. A homolog of Drosophila grainy head is essential for epidermal integrity in mice. Science 2005; 308: 411-413.
    • (2005) Science , vol.308 , pp. 411-413
    • Ting, S.B.1    Caddy, J.2    Hislop, N.3
  • 13
    • 84858293792 scopus 로고    scopus 로고
    • ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation
    • Sen GL, Boxer LD, Webster DE, et al. ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation. Dev Cell 2012; 22: 669-677.
    • (2012) Dev Cell , vol.22 , pp. 669-677
    • Sen, G.L.1    Boxer, L.D.2    Webster, D.E.3
  • 14
    • 40949147805 scopus 로고    scopus 로고
    • Perturbed desmosomal cadherin expression in grainy head-like 1-null mice
    • Wilanowski T, Caddy J, Ting SB, et al. Perturbed desmosomal cadherin expression in grainy head-like 1-null mice. EMBO J 2008; 27: 886-897.
    • (2008) EMBO J , vol.27 , pp. 886-897
    • Wilanowski, T.1    Caddy, J.2    Ting, S.B.3
  • 15
    • 70349652084 scopus 로고    scopus 로고
    • C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation
    • Lopez RG, Garcia-Silva S, Moore SJ, et al. C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation. Nat Cell Biol 2009; 11: 1181-1190.
    • (2009) Nat Cell Biol , vol.11 , pp. 1181-1190
    • Lopez, R.G.1    Garcia-Silva, S.2    Moore, S.J.3
  • 16
    • 84857817163 scopus 로고    scopus 로고
    • Slug and Sox9 cooperatively determine the mammary stem cell state
    • Guo W, Keckesova Z, Donaher JL, et al. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell 2012; 148: 1015-1028.
    • (2012) Cell , vol.148 , pp. 1015-1028
    • Guo, W.1    Keckesova, Z.2    Donaher, J.L.3
  • 17
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3
  • 18
    • 84887273608 scopus 로고    scopus 로고
    • Epithelial plasticity: A common theme in embryonic and cancer cells
    • Nieto MA,. Epithelial plasticity: A common theme in embryonic and cancer cells. Science 2013; 342: 1234850.
    • (2013) Science , vol.342 , pp. 1234850
    • Nieto, M.A.1
  • 19
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • De Craene B, Berx G,. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 2013; 13: 97-110.
    • (2013) Nat Rev Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 20
    • 78149282262 scopus 로고    scopus 로고
    • Snail transcription factors in keratinocytes: Enough to make your skin crawl
    • Sou PW, Delic NC, Halliday GM, et al. Snail transcription factors in keratinocytes: Enough to make your skin crawl. Int J Biochem Cell Biol 2010; 42: 1940-1944.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1940-1944
    • Sou, P.W.1    Delic, N.C.2    Halliday, G.M.3
  • 22
    • 84865839326 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: Insights from development
    • Lim J, Thiery JP,. Epithelial-mesenchymal transitions: Insights from development. Development 2012; 139: 3471-3486.
    • (2012) Development , vol.139 , pp. 3471-3486
    • Lim, J.1    Thiery, J.P.2
  • 23
    • 69049106307 scopus 로고    scopus 로고
    • Cutaneous wound reepithelialization is compromised in mice lacking functional Slug (Snai2)
    • Hudson LG, Newkirk KM, Chandler HL, et al. Cutaneous wound reepithelialization is compromised in mice lacking functional Slug (Snai2). J Dermatol Sci 2009; 56: 19-26.
    • (2009) J Dermatol Sci , vol.56 , pp. 19-26
    • Hudson, L.G.1    Newkirk, K.M.2    Chandler, H.L.3
  • 24
    • 84870845421 scopus 로고    scopus 로고
    • Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
    • Tsai JH, Donaher JL, Murphy DA, et al. Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis. Cancer Cell 2012; 22: 725-736.
    • (2012) Cancer Cell , vol.22 , pp. 725-736
    • Tsai, J.H.1    Donaher, J.L.2    Murphy, D.A.3
  • 25
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • Bolos V, Peinado H, Perez-Moreno MA, et al. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors. J Cell Sci 2003; 116: 499-511.
    • (2003) J Cell Sci , vol.116 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3
  • 26
    • 0033197879 scopus 로고    scopus 로고
    • SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
    • Inukai T, Inoue A, Kurosawa H, et al. SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol Cell 1999; 4: 343-352.
    • (1999) Mol Cell , vol.4 , pp. 343-352
    • Inukai, T.1    Inoue, A.2    Kurosawa, H.3
  • 27
    • 38149090202 scopus 로고    scopus 로고
    • Microarray analysis demonstrates a role for Slug in epidermal homeostasis
    • Newkirk KM, MacKenzie DA, Bakaletz AP, et al. Microarray analysis demonstrates a role for Slug in epidermal homeostasis. J Invest Dermatol 2008; 128: 361-369.
    • (2008) J Invest Dermatol , vol.128 , pp. 361-369
    • Newkirk, K.M.1    Mackenzie, D.A.2    Bakaletz, A.P.3
  • 28
    • 33746365139 scopus 로고    scopus 로고
    • Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes
    • Turner FE, Broad S, Khanim FL, et al. Slug regulates integrin expression and cell proliferation in human epidermal keratinocytes. J Biol Chem 2006; 281: 21321-21331.
    • (2006) J Biol Chem , vol.281 , pp. 21321-21331
    • Turner, F.E.1    Broad, S.2    Khanim, F.L.3
  • 29
    • 58549116088 scopus 로고    scopus 로고
    • Slug/Snai2 is a downstream mediator of epidermal growth factor receptor-stimulated reepithelialization
    • Kusewitt DF, Choi C, Newkirk KM, et al. Slug/Snai2 is a downstream mediator of epidermal growth factor receptor-stimulated reepithelialization. J Invest Dermatol 2009; 129: 491-495.
    • (2009) J Invest Dermatol , vol.129 , pp. 491-495
    • Kusewitt, D.F.1    Choi, C.2    Newkirk, K.M.3
  • 30
    • 84867021989 scopus 로고    scopus 로고
    • Transcriptional amplification in tumor cells with elevated c-Myc
    • Lin CY, Loven J, Rahl PB, et al. Transcriptional amplification in tumor cells with elevated c-Myc. Cell 2012; 151: 56-67.
    • (2012) Cell , vol.151 , pp. 56-67
    • Lin, C.Y.1    Loven, J.2    Rahl, P.B.3
  • 31
    • 84867010006 scopus 로고    scopus 로고
    • C-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
    • Nie Z, Hu G, Wei G, et al. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 2012; 151: 68-79.
    • (2012) Cell , vol.151 , pp. 68-79
    • Nie, Z.1    Hu, G.2    Wei, G.3
  • 32
    • 65649106153 scopus 로고    scopus 로고
    • Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression
    • Reuter JA, Ortiz-Urda S, Kretz M, et al. Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression. Cancer Cell 2009; 15: 477-488.
    • (2009) Cancer Cell , vol.15 , pp. 477-488
    • Reuter, J.A.1    Ortiz-Urda, S.2    Kretz, M.3
  • 33
    • 63849130585 scopus 로고    scopus 로고
    • Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers
    • Alves CC, Carneiro F, Hoefler H, et al. Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers. Front Biosci (Landmark Ed) 2009; 14: 3035-3050.
    • (2009) Front Biosci (Landmark Ed) , vol.14 , pp. 3035-3050
    • Alves, C.C.1    Carneiro, F.2    Hoefler, H.3
  • 34
    • 0842310832 scopus 로고    scopus 로고
    • Restriction enzyme-generated siRNA (REGS) vectors and libraries
    • Sen G, Wehrman TS, Myers JW, et al. Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nat Genet 2004; 36: 183-189.
    • (2004) Nat Genet , vol.36 , pp. 183-189
    • Sen, G.1    Wehrman, T.S.2    Myers, J.W.3
  • 35
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Consortium EP, Bernstein BE, Birney E, et al. An integrated encyclopedia of DNA elements in the human genome. Nature 2012; 489: 57-74.
    • (2012) Nature , vol.489 , pp. 57-74
    • Consortium, E.P.1    Bernstein, B.E.2    Birney, E.3
  • 36
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell C, Pachter L, Salzberg SL,. TopHat: Discovering splice junctions with RNA-Seq. Bioinformatics 2009; 25: 1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 37
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell C, Williams BA, Pertea G, et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat Biotechnol 2010; 28: 511-515.
    • (2010) Nat Biotechnol , vol.28 , pp. 511-515
    • Trapnell, C.1    Williams, B.A.2    Pertea, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.