Progenitor function in self-renewing human epidermis is maintained by the exosome

Cell Stem Cell

Volumn 11, Issue 1, 2012, Pages 127-135

  Mistry, Devendra S ^a   Chen, Yifang ^a   Sen, George L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; EXOSC9 PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GRHL3; UNCLASSIFIED DRUG;

ARTICLE; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL FUNCTION; CELL LOSS; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; DOWN REGULATION; EPIDERMIS; EXOSOME; GENE EXPRESSION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; RNA DEGRADATION; STEM CELL;

CELL DIFFERENTIATION; CELL PROLIFERATION; DNA-BINDING PROTEINS; DOWN-REGULATION; EPIDERMIS; EXOSOMES; HUMANS; MALE; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; STEM CELLS; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 84863613835     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2012.04.022     Document Type: Article

References (36)

1. E.D. Andrulis, J. Werner, A. Nazarian, H. Erdjument-Bromage, P. Tempst, and J.T. Lis The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila Nature 420 2002 837 841 (Pubitemid 36019634)
2. D. Belostotsky Exosome complex and pervasive transcription in eukaryotic genomes Curr. Opin. Cell Biol. 21 2009 352 358
3. D.A. Belostotsky, and L.E. Sieburth Kill the messenger: mRNA decay and plant development Curr. Opin. Plant Biol. 12 2009 96 102
4. C. Blanpain, and E. Fuchs Epidermal stem cells of the skin Annu. Rev. Cell Dev. Biol. 22 2006 339 373
5. K.P. Callahan, and J.S. Butler Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p Nucleic Acids Res. 36 2008 6645 6655
6. J.A. Chekanova, B.D. Gregory, S.V. Reverdatto, H. Chen, R. Kumar, T. Hooker, J. Yazaki, P. Li, N. Skiba, and Q. Peng Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome Cell 131 2007 1340 1353 (Pubitemid 350297418)
7. C. Ciaudo, A. Bourdet, M. Cohen-Tannoudji, H.C. Dietz, C. Rougeulle, and P. Avner Nuclear mRNA degradation pathway(s) are implicated in Xist regulation and X chromosome inactivation PLoS Genet. 2 2006 e94
8. J. de la Cruz, D. Kressler, D. Tollervey, and P. Linder Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3′ end formation of 5.8S rRNA in Saccharomyces cerevisiae EMBO J. 17 1998 1128 1140 (Pubitemid 28077666)
9. E. Ezhkova, H.A. Pasolli, J.S. Parker, N. Stokes, I.H. Su, G. Hannon, A. Tarakhovsky, and E. Fuchs Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells Cell 136 2009 1122 1135
10. E. Ezhkova, W.H. Lien, N. Stokes, H.A. Pasolli, J.M. Silva, and E. Fuchs EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair Genes Dev. 25 2011 485 498
11. N.L. Garneau, J. Wilusz, and C.J. Wilusz The highways and byways of mRNA decay Nat. Rev. Mol. Cell Biol. 8 2007 113 126 (Pubitemid 46432531)
12. J. Houseley, and D. Tollervey The many pathways of RNA degradation Cell 136 2009 763 776
13. J. Houseley, J. LaCava, and D. Tollervey RNA-quality control by the exosome Nat. Rev. Mol. Cell Biol. 7 2006 529 539 (Pubitemid 44036458)
14. P.A. Khavari Modelling cancer in human skin tissue Nat. Rev. Cancer 6 2006 270 280
15. D.L. Kiss, and E.D. Andrulis Genome-wide analysis reveals distinct substrate specificities of Rrp6, Dis3, and core exosome subunits RNA 16 2010 781 791
16. G.J. Leclerc, G.M. Leclerc, and J.C. Barredo Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines Cancer Cell Int. 2 2002 1
17. R.G. Lopez, S. Garcia-Silva, S.J. Moore, O. Bereshchenko, A.B. Martinez-Cruz, O. Ermakova, E. Kurz, J.M. Paramio, and C. Nerlov C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation Nat. Cell Biol. 11 2009 1181 1190
18. M. Lubas, M.S. Christensen, M.S. Kristiansen, M. Domanski, L.G. Falkenby, S. Lykke-Andersen, J.S. Andersen, A. Dziembowski, and T.H. Jensen Interaction profiling identifies the human nuclear exosome targeting complex Mol. Cell 43 2011 624 637
19. L. Milligan, L. Decourty, C. Saveanu, J. Rappsilber, H. Ceulemans, A. Jacquier, and D. Tollervey A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts Mol. Cell. Biol. 28 2008 5446 5457
20. P. Mitchell, E. Petfalski, R. Houalla, A. Podtelejnikov, M. Mann, and D. Tollervey Rrp47p is an exosome-associated protein required for the 3′ processing of stable RNAs Mol. Cell. Biol. 23 2003 6982 6992 (Pubitemid 37214665)
21. H. Neil, C. Malabat, Y. d'Aubenton-Carafa, Z. Xu, L.M. Steinmetz, and A. Jacquier Widespread bidirectional promoters are the major source of cryptic transcripts in yeast Nature 457 2009 1038 1042
22. P. Preker, J. Nielsen, S. Kammler, S. Lykke-Andersen, M.S. Christensen, C.K. Mapendano, M.H. Schierup, and T.H. Jensen RNA exosome depletion reveals transcription upstream of active human promoters Science 322 2008 1851 1854
23. G. Schilders, R. Raijmakers, J.M. Raats, and G.J. Pruijn MPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturation Nucleic Acids Res. 33 2005 6795 6804 (Pubitemid 41830485)
24. G. Schilders, E. van Dijk, and G.J. Pruijn C1D and hMtr4p associate with the human exosome subunit PM/Scl-100 and are involved in pre-rRNA processing Nucleic Acids Res. 35 2007 2564 2572 (Pubitemid 47073670)
25. J.A. Segre Epidermal barrier formation and recovery in skin disorders J. Clin. Invest. 116 2006 1150 1158
26. J.A. Segre, C. Bauer, and E. Fuchs Klf4 is a transcription factor required for establishing the barrier function of the skin Nat. Genet. 22 1999 356 360 (Pubitemid 29369526)
27. G.L. Sen Remembering one's identity: the epigenetic basis of stem cell fate decisions FASEB J. 25 2011 2123 2128
28. G.L. Sen, D.E. Webster, D.I. Barragan, H.Y. Chang, and P.A. Khavari Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3 Genes Dev. 22 2008 1865 1870 (Pubitemid 352008635)
29. G.L. Sen, J.A. Reuter, D.E. Webster, L. Zhu, and P.A. Khavari DNMT1 maintains progenitor function in self-renewing somatic tissue Nature 463 2010 563 567
30. G.L. Sen, L.D. Boxer, D.E. Webster, R.T. Bussat, K. Qu, B.J. Zarnegar, D. Johnston, Z. Siprashvili, and P.A. Khavari ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation Dev. Cell 22 2012 669 677
31. M. Senoo, F. Pinto, C.P. Crum, and F. McKeon p63 Is essential for the proliferative potential of stem cells in stratified epithelia Cell 129 2007 523 536 (Pubitemid 46660965)
32. S.B. Ting, J. Caddy, N. Hislop, T. Wilanowski, A. Auden, L.L. Zhao, S. Ellis, P. Kaur, Y. Uchida, and W.M. Holleran A homolog of Drosophila grainy head is essential for epidermal integrity in mice Science 308 2005 411 413 (Pubitemid 40530078)
33. R. Tomecki, M.S. Kristiansen, S. Lykke-Andersen, A. Chlebowski, K.M. Larsen, R.J. Szczesny, K. Drazkowska, A. Pastula, J.S. Andersen, and P.P. Stepien The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L EMBO J. 29 2010 2342 2357
34. A.B. Truong, M. Kretz, T.W. Ridky, R. Kimmel, and P.A. Khavari p63 regulates proliferation and differentiation of developmentally mature keratinocytes Genes Dev. 20 2006 3185 3197 (Pubitemid 44790632)
35. E.L. van Dijk, C.L. Chen, Y. d'Aubenton-Carafa, S. Gourvennec, M. Kwapisz, V. Roche, C. Bertrand, M. Silvain, P. Legoix-Né, and S. Loeillet XUTs are a class of Xrn1-sensitive antisense regulatory non-coding RNA in yeast Nature 475 2011 114 117
36. L. Vasiljeva, and S. Buratowski Nrd1 interacts with the nuclear exosome for 3′ processing of RNA polymerase II transcripts Mol. Cell 21 2006 239 248 (Pubitemid 43099939)