In utero and postnatal vitamin D exposure and allergy risk

Expert Opinion on Drug Safety

Volumn 13, Issue 12, 2014, Pages 1601-1611

  Rueter, Kristina ^a,b,c   Siafarikas, Aris ^b,c   Prescott, Susan L ^a,b,c,d   Palmer, Debra J ^a,c  

^a International Inflammation (In FLAME) Network of the World Universities Network   (United Kingdom)

^b PRINCESS MARGARET HOSPITAL FOR CHILDREN   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Allergic disease; Infancy; Pregnancy; Prevention; Vitamin D

Indexed keywords

VITAMIN D;

ALLERGIC DISEASE; ALLERGY; BEHAVIOR; CHILDHOOD; DRUG SAFETY; HUMAN; IMMUNOPATHOLOGY; INFLAMMATORY DISEASE; NONHUMAN; OBSERVATIONAL STUDY; PRENATAL EXPOSURE; REVIEW; RISK ASSESSMENT; SUN EXPOSURE; SUNLIGHT; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION; ADVERSE EFFECTS; ANIMAL; CHEMICALLY INDUCED; DIET SUPPLEMENTATION; FEMALE; HYPERSENSITIVITY; POSTOPERATIVE CARE; PREGNANCY; RISK;

ANIMALS; DIETARY SUPPLEMENTS; FEMALE; HUMANS; HYPERSENSITIVITY; POSTOPERATIVE CARE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RISK; VITAMIN D;

EID: 84912043181     PISSN: 14740338     EISSN: 1744764X     Source Type: Journal    
DOI: 10.1517/14740338.2014.961913     Document Type: Review

References (86)

1. Pawankar R, Canonica GW, Holgate ST, Lockey RF. Allergic diseases and asthma: A major global health concern. Curr Opin Allergy Clin Immunol 2012;12(1):39-41
2. Shaker M. New insights into the allergic march. Curr Opin Pediatr 2014;26(4):516-20
3. Spergel JM. From atopic dermatitis to asthma: the atopic march. Ann Allergy Asthma Immunol 2010;105(2):99-106; quiz 107-109, 117
4. Osborne NJ, Koplin JJ, Martin PE, et al. Prevalence of challenge-proven Igemediated food allergy using populationbased sampling and predetermined challenge criteria in infants. J Allergy Clin Immunol 2011;127(3):668-76; e661-662
5. Williams H, Stewart A, von Mutius E, et al. International Study of Asthma, Allergies in Childhood. Is eczema really on the increase worldwide J Allergy Clin Immunol 2008;121(4):947-54; e915
6. Bjorksten B, Clayton T, Ellwood P, et al. Worldwide time trends for symptoms of rhinitis and conjunctivitis: phase III of the International Study of Asthma and Allergies in Childhood. Pediatr Allergy Immunol 2008;19(2):110-24
7. O'Connell EJ. The burden of atopy and asthma in children. Allergy 2004;59(Suppl 78):7-11
8. Alanne S, Maskunitty A, Nermes M, et al. Costs of allergic diseases from birth to two years in Finland. Public Health 2012;126(10):866-72
9. Black PN, Sharpe S. Dietary fat and asthma: is there a connection Eur Respir J 1997;10(1):6-12
10. Strachan DP. Family size, infection and atopy: the first decade of the hygiene hypothesis. Thorax 2000;55(Suppl 1):S2-10
11. Franco JM, Gurgel R, Sole D, et al. Socio-environmental conditions and geographical variability of asthma prevalence in northeast brazil. Allergol Immunopathol (Madr) 2009;37(3):116-21
12. Krstic G. Asthma prevalence associated with geographical latitude and regional insolation in the United States of America and Australia. PLoS One 2011;6(4):e18492
13. Osborne NJ, Ukoumunne OC, Wake M, Allen KJ. Prevalence of eczema and food allergy is associated with latitude in Australia. J Allergy Clin Immunol 2012;129(3):865-7
14. Weiland SK, Husing A, Strachan DP, et al. Climate and the prevalence of symptoms of asthma, allergic rhinitis, and atopic eczema in children. Occup Environ Med 2004;61(7):609-15
15. Camargo CA Jr, Clark S, Kaplan MS, et al. Regional differences in epipen prescriptions in the United States: the potential role of vitamin D. J Allergy Clin Immunol 2007;120(1):131-6
16. Mullins RJ, Clark S, Camargo CA Jr. Regional variation in epinephrine autoinjector prescriptions in Australia: more evidence for the vitamin Danaphylaxis hypothesis. Ann Allergy Asthma Immunol 2009;103(6):488-95
17. Mullins RJ, Clark S, Camargo CA Jr. Regional variation in infant hypoallergenic formula prescriptions in Australia. Pediatr Allergy Immunol 2010;21(2 Pt 2):e413-20
18. Baiz N, Dargent-Molina P, Wark JD, et al. Cord serum 25-hydroxyvitamin D and risk of early childhood transient wheezing and atopic dermatitis. J Allergy Clin Immunol 2014;133(1):147-53
19. Jones AP, Palmer D, Zhang G, Prescott SL. Cord blood 25-hydroxyvitamin D3 and allergic disease during infancy. Pediatrics 2012;130(5):e1128-35
20. Gale CR, Robinson SM, Harvey NC, et al. Maternal vitamin D status during pregnancy and child outcomes. Eur J Clin Nutr 2008;62(1):68-77
21. Weisse K, Winkler S, Hirche F, et al. Maternal and newborn vitamin D status and its impact on food allergy development in the German Lina cohort study. Allergy 2013;68(2):220-8
22. Holick MF. Vitamin D deficiency. N Engl J Med 2007;357(3):266-81
23. Chen TC, Chimeh F, Lu Z, et al. Factors that influence the cutaneous synthesis and dietary sources of vitamin D. Arch Biochem Biophys 2007;460(2):213-17
24. Wagner CL, Greer FR; American Academy of Pediatrics Committee on Nutrition. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics 2008;122(5):1142-52
25. Wharton B, Bishop N. Rickets. Lancet 2003;362(9393):1389-400
26. Greer FR. Issues in establishing vitamin D recommendations for infants and children. Am J Clin Nutr 2004;80(6 Suppl):1759S-62S
27. Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: An endocrine society clinical practice guideline. J Clin Endocrinol Metab 2011;96(7):1911-30
28. Onal H, Adal E, Alpaslan S, et al. Is daily 400 IU of vitamin D supplementation appropriate for every country: A cross-sectional study. Eur J Nutr 2010;49(7):395-400
29. Lai JK, Lucas RM, Clements MS, et al. Assessing vitamin D status: pitfalls for the unwary. Mol Nutr Food Res 2010;54(8):1062-71
30. Paxton GA, Teale GR, Nowson CA, et al. Vitamin D and health in pregnancy, infants, children and adolescents in Australia and New Zealand: A position statement. Med J Aus 2013;198(3):142-3
31. Salle BL, Delvin EE, Lapillonne A, et al. Perinatal metabolism of vitamin D. Am J Clin Nutr 2000;71(5 Suppl):1317S-24S
32. Lee JM, Smith JR, Philipp BL, et al. Vitamin D deficiency in a healthy group of mothers and newborn infants. Clin Pediatr 2007;46(1):42-4
33. Hollis BW, Johnson D, Hulsey TC, et al. Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness. J Bone Mineral Res 2011;26(10):2341-57
34. Greer FR, Hollis BW, Cripps DJ, Tsang RC. Effects of maternal ultraviolet B irradiation on vitamin D content of human milk. J Pediatr 1984;105(3):431-3
35. Hollis BW, Roos BA, Draper HH, Lambert PW. Vitamin D and its metabolites in human and bovine milk. J Nutr 1981;111(7):1240-8
36. Specker BL, Valanis B, Hertzberg V, et al. Sunshine exposure and serum 25-hydroxyvitamin D concentrations in exclusively breast-fed infants. J Pediatr 1985;107(3):372-6
37. Hollis BW, Wagner CL. The role of the parent compound vitamin D with respect to metabolism and function: why clinical dose intervals can affect clinical outcomes. J Clin Endocrinol Metab 2013;98:4619-28
38. Hollis BW, Wagner CL. Vitamin D requirements during lactation: high-dose maternal supplementation as therapy to prevent hypovitaminosis D for both the mother and the nursing infant. Am J Clin Nutr 2004;80(6 Suppl):1752S-8S
39. Wagner CL, Hulsey TC, Fanning D, et al. High-dose vitamin D3 supplementation in a cohort of breastfeeding mothers and their infants: A 6-month follow-up pilot study. Breastfeed Med 2006;1(2):59-70
40. Gallo S, Comeau K, Vanstone C, et al. Effect of different dosages of oral vitamin D supplementation on vitamin D status in healthy, breastfed infants: A randomized trial. JAMA 2013;309(17):1785-92
41. Ziegler EE, Nelson SE, Jeter JM. Vitamin D supplementation of breastfed infants: A randomized dose-response trial. Pediatr Res 2014;76(2):177-83
42. Braegger C, Campoy C, Colomb V, et al. Vitamin D in the healthy European paediatric population. J Pediatr Gastroenterol Nutr 2013;56(6):692-701
43. Godel JC. Vitamin D supplementation: recommendations for Canadian mothers and infants. Paediatr Child Health 2007;12(7):583-98
44. Vogiatzi MG, Jacobson-Dickman E, DeBoer MD. Vitamin D supplementation and risk of toxicity in pediatrics: A review of current literature. J Clin Endocrinol Metab 2014;99(4):1132-41
45. Misselwitz J, Hesse V, Markestad T. Nephrocalcinosis, hypercalciuria and elevated serum levels of 1,25-dihydroxyvitamin D in children. Possible link to vitamin D toxicity. Acta Paediatr Scand 1990;79(6-7):637-43
46. Ronnefarth G, Misselwitz J. Nephrocalcinosis in children: A retrospective survey. Pediatric Nephrol 2000;14(10-11):1016-21
47. Barrueto F Jr, Wang-Flores HH, Howland MA, et al. Acute vitamin D intoxication in a child. Pediatrics 2005;116(3):e453-6
48. Jones G. Pharmacokinetics of vitamin D toxicity. Am J Clin Nutr 2008;88(2):582S-6S
49. Schlingmann KP, Kaufmann M, Weber S, et al. Mutations in cyp24a1 and idiopathic infantile hypercalcemia. N Engl J Med 2011;365(5):410-21
50. Hart PH, Gorman S, Finlay-Jones JJ. Modulation of the immune system by UV radiation: more than just the effects of vitamin D Nat Rev Immunol 2011;11(9):584-96
51. Cantorna MT, Zhu Y, Froicu M, Wittke A. Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system. Am J Clin Nutr 2004;80(6 Suppl):1717S-20S
52. Adams JS, Hewison M. Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity. Nat Clin Pract Endocrinol Metab 2008;4(2):80-90
53. Gorman S, Judge MA, Burchell JT, et al. 1,25-dihydroxyvitamin D3 enhances the ability of transferred cd4+ cd25+ cells to modulate t helper type 2-driven asthmatic responses. Immunology 2010;130(2):181-92
54. Muehleisen B, Gallo RL. Vitamin D in allergic disease: shedding light on a complex problem. J Allergy Clin Immunol 2013;131(2):324-9
55. Camargo CA Jr, Rifas-Shiman SL, Litonjua AA, et al. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr 2007;85(3):788-95
56. Devereux G, Litonjua AA, Turner SW, et al. Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr 2007;85(3):853-9
57. Miyake Y, Sasaki S, Tanaka K, Hirota Y. Dairy food, calcium and vitamin D intake in pregnancy, and wheeze and eczema in infants. Eur Respir J 2010;35(6):1228-34
58. Erkkola M, Kaila M, Nwaru BI, et al. Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children. Clin Exp Allergy 2009;39(6):875-82
59. Nwaru BI, Ahonen S, Kaila M, et al. Maternal diet during pregnancy and allergic sensitization in the offspring by 5 yrs of age: A prospective cohort study. Pediatr Allergy Immunol 2010;21(1 Pt 1):29-37
60. Pike KC, Inskip HM, Robinson S, et al. Maternal late-pregnancy serum 25-hydroxyvitamin D in relation to childhood wheeze and atopic outcomes. Thorax 2012;67(11):950-6
61. Dunstan JA, Mori TA, Barden A, et al. Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: A randomized, controlled trial. J Allergy Clin Immunol 2003;112(6):1178-84
62. Furuhjelm C, Warstedt K, Larsson J, et al. Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy. Acta Paediatrica 2009;98(9):1461-7
63. Olsen SF, Osterdal ML, Salvig JD, et al. Fish oil intake compared with olive oil intake in late pregnancy and asthma in the offspring: 16 y of registry-based follow-up from a randomized controlled trial. Am J Clin Nutr 2008;88(1):167-75
64. Palmer DJ, Sullivan T, Gold MS, et al. Effect of n-3 long chain polyunsaturated fatty acid supplementation in pregnancy on infants' allergies in first year of life: randomised controlled trial. BMJ 2012;344:e184
65. Morales E, Romieu I, Guerra S, et al. Maternal vitamin D status in pregnancy and risk of lower respiratory tract infections, wheezing, and asthma in offspring. Epidemiology 2012;23(1):64-71
66. Wills AK, Shaheen SO, Granell R, et al. Maternal 25-hydroxyvitamin D and its association with childhood atopic outcomes and lung function. Clin Exp Allergy 2013;43(10):1180-8
67. Cadario F, Savastio S, Pozzi E, et al. Vitamin D status in cord blood and newborns: ethnic differences. Italian J Pediatr 2013;39:35
68. Heckmatt JZ, Peacock M, Davies AE, et al. Plasma 25-hydroxyvitamin D in pregnant asian women and their babies. Lancet 1979;2(8142):546-8
69. Grant CC, Stewart AW, Scragg R, et al. Vitamin D during pregnancy and infancy and infant serum 25-hydroxyvitamin D concentration. Pediatrics 2014;133(1):e143-53
70. Wagner CL, McNeil RB, Johnson DD, et al. Health characteristics and outcomes of two randomized vitamin D supplementation trials during pregnancy: A combined analysis. J Steroid Biochem Mol Biol 2013;136:313-20
71. Goldring ST, Griffiths CJ, Martineau AR, et al. Prenatal vitamin D supplementation and child respiratory health: A randomised controlled trial. PLoS One 2013;8(6):e66627
72. Murdoch DR, Slow S, Chambers ST, et al. Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the vidaris randomized controlled trial. JAMA 2012;308(13):1333-9
73. Groenman F, Unger S, Post M. The molecular basis for abnormal human lung development. Biol Neonate 2005;87(3):164-77
74. Heaney RP, Recker RR, Grote J, et al. Vitamin D(3) is more potent than vitamin D(2) in humans. J Clin Endocrinol Metab 2011;96(3):E447-52
75. Hypponen E, Boucher BJ. Avoidance of vitamin D deficiency in pregnancy in the United Kingdom: the case for a unified approach in national policy. Br J Nutr 2010;104(3):309-14
76. Chawes BL, Bonnelykke K, Jensen PF, et al. Cord blood 25(OH)-vitamin D deficiency and childhood asthma, allergy and eczema: the COPSAC2000 birth cohort study. PLoS One 2014;9(6):e99856
77. Camargo CA Jr, Ingham T, Wickens K, et al. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics 2011;127(1):e180-7
78. Rothers J, Wright AL, Stern DA, et al. Cord blood 25-hydroxyvitamin D levels are associated with aeroallergen sensitization in children from Tucson, Arizona. J Allergy Clin Immunol 2011;128(5):1093-9; e1091-1095
79. Jartti T, Kuusipalo H, Vuorinen T, et al. Allergic sensitization is associated with rhinovirus-, but not other virus-, induced wheezing in children. Pediatr Allergy Immunol 2010;21(7):1008-14
80. Hypponen E, Berry DJ, Wjst M, Power C. Serum 25-hydroxyvitamin D and IgE-A significant but nonlinear relationship. Allergy 2009;64(4):613-20
81. Matheu V, Back O, Mondoc E, Issazadeh-Navikas S. Dual effects of vitamin D-induced alteration of TH1/TH2 cytokine expression: enhancing IgE production and decreasing airway eosinophilia in murine allergic airway disease. J Allergy Clin Immunol 2003;112(3):585-92
82. Liu X, Wang G, Hong X, et al. Gene-vitamin D interactions on food sensitization: A prospective birth cohort study. Allergy 2011;66(11):1442-8
83. Liu X, Arguelles L, Zhou Y, et al. Longitudinal trajectory of vitamin D status from birth to early childhood in the development of food sensitization. Pediatr Res 2013;74(3):321-6
84. Back O, Blomquist HK, Hernell O, Stenberg B. Does vitamin D intake during infancy promote the development of atopic allergy Acta Derm Venereol 2009;89(1):28-32
85. Norizoe C, Akiyama N, Segawa T, et al. Increased food allergy and vitamin D: randomized, double-blind, placebocontrolled trial. Pediatr Int 2014;56(1):6-12
86. Hart PH, Gorman S. Exposure to UV wavelengths in sunlight suppresses immunity. To what extent is uv-induced vitamin D3 the mediator responsible Clin Biochem Rev 2013;34(1):3-13