Prenatal vitamin D3 supplementation suppresses LL-37 peptide expression in ex vivo activated neonatal macrophages but not their killing capacity

British Journal of Nutrition

Volumn 112, Issue 6, 2014, Pages 908-915

  Raqib, Rubhana ^a   Ly, Anna ^b   Akhtar, Evana ^a   Mily, Akhirunnesa ^a   Perumal, Nandita ^b   Al Mahmud, Abdullah ^a   Rekha, Rokeya Sultana ^a,c   Baqui, Abdullah Hel ^d   Roth, Daniel E ^b  

^a INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH   (Bangladesh)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c KAROLINSKA INSTITUTE   (Sweden)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Antimicrobial peptides; Innate immunity; Macrophages; Neonates; Vitamin D3

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; COLECALCIFEROL; MESSENGER RNA; PLACEBO; RNA 18S; TOLL LIKE RECEPTOR 4; CATHELICIDIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE; IMMUNOLOGIC FACTOR;

ADULT; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; COPY NUMBER VARIATION; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; ESCHERICHIA COLI; EX VIVO STUDY; EXTRACELLULAR FLUID; FEMALE; GENETIC TRANSCRIPTION; GESTATIONAL AGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOMODULATION; INFANT; INNATE IMMUNITY; LIMIT OF DETECTION; MACROPHAGE; MALE; MONOCYTE; NORMAL HUMAN; PATTERN RECOGNITION; POLYMERASE CHAIN REACTION; PREGNANCY; PROTEIN EXPRESSION; PROTEIN INDUCTION; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; TANDEM MASS SPECTROMETRY; UMBILICAL CORD BLOOD; VITAMIN SUPPLEMENTATION; YOUNG ADULT; ADOLESCENT; ANTAGONISTS AND INHIBITORS; BANGLADESH; BLOOD; CELL CULTURE; CYTOLOGY; DIET SUPPLEMENTATION; FETUS BLOOD; GENETICS; IMMUNOLOGY; MACROPHAGE ACTIVATION; MATERNAL NUTRITION; METABOLISM; PHAGOCYTOSIS; PREGNANCY COMPLICATIONS; THIRD TRIMESTER PREGNANCY; VITAMIN D DEFICIENCY;

ADOLESCENT; ADULT; BANGLADESH; CATHELICIDINS; CELLS, CULTURED; CHOLECALCIFEROL; COHORT STUDIES; DIETARY SUPPLEMENTS; FEMALE; FETAL BLOOD; HUMANS; IMMUNITY, INNATE; IMMUNOLOGIC FACTORS; MACROPHAGE ACTIVATION; MACROPHAGES; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PHAGOCYTOSIS; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY TRIMESTER, THIRD; VITAMIN D DEFICIENCY; YOUNG ADULT;

EID: 84912043133     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114514001512     Document Type: Article

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