Alloxan reduces amplitude of ventricular myocyte shortening and intracellular Ca2+ without altering L-type Ca2+ current, sarcoplasmic reticulum Ca2+ content or myofilament sensitivity to Ca2+ in Wistar rats

Molecular and Cellular Biochemistry

Volumn 340, Issue 1-2, 2010, Pages 115-123

  Salem, Khawla Abdulla ^a   Qureshi, Anwar ^a   Ljubisavijevic, Milos ^a   Oz, Murat ^a   Isaev, Dmytro ^a   Hussain, Munir ^b   Howarth, Frank Christopher ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Alloxan; Cardiac muscle contraction; Heart; Intracellular calcium; Ventricular myocytes

Indexed keywords

ALLOXAN; CAFFEINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; FURA 2; CALCIUM;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; EVOKED RESPONSE; HEART CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; HEART VENTRICLE; INOTROPISM; MALE; MOLECULAR MECHANICS; MYOFILAMENT; NONHUMAN; RAT; SARCOPLASMIC RETICULUM; ACTIN FILAMENT; ANIMAL; CALCIUM SIGNALING; DOSE RESPONSE; DRUG EFFECTS; ELECTROSTIMULATION; IN VITRO STUDY; MEMBRANE POTENTIAL; METABOLISM; TIME; WISTAR RAT;

ALLOXAN; ANIMALS; CAFFEINE; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; HEART VENTRICLES; MALE; MEMBRANE POTENTIALS; MICROFILAMENTS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; SARCOPLASMIC RETICULUM; TIME FACTORS; ACTIN CYTOSKELETON; IN VITRO TECHNIQUES;

ANIMALIA; RATTUS NORVEGICUS;

EID: 77954425478     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0408-7     Document Type: Article

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