High GINS2 transcript level predicts poor prognosis and correlates with high histological grade and endocrine therapy resistance through mammary cancer stem cells in breast cancer patients

Breast Cancer Research and Treatment

Volumn 148, Issue 2, 2014, Pages 423-436

  Zheng, Ming ^a,b   Zhou, Yinghui ^a   Yang, Xiangmin ^a   Tang, Juan ^a   Wei, Ding ^a   Zhang, Yang ^a   Jiang, Jian Li ^a   Chen, Zhi nan ^a   Zhu, Ping ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; Endocrine therapy resistance; GINS2; Mammary cancer stem cell; Metastasis; Relapse

Indexed keywords

ESTROGEN RECEPTOR; PROTEIN P53; TAMOXIFEN; TUMOR MARKER; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; GINS2 PROTEIN, HUMAN; MESSENGER RNA; NONHISTONE PROTEIN; PROGESTERONE RECEPTOR; TP53 PROTEIN, HUMAN;

ADULT; ARTICLE; BREAST CANCER; CANCER GRADING; CANCER HORMONE THERAPY; CANCER PATIENT; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER RESISTANCE; CANCER STEM CELL; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SPECIFIC SURVIVAL; DISTANT METASTASIS FREE SURVIVAL; DOWN REGULATION; FEMALE; GENE; GENE FUNCTION; GENE MUTATION; GENE OVEREXPRESSION; GENE SET ENRICHMENT ANALYSIS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GINS2 GENE; HUMAN; LUNG METASTASIS; MAMMARY CANCER STEM CELL; RECURRENCE FREE SURVIVAL; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; UPREGULATION; BREAST NEOPLASMS; CANCER STAGING; COHORT ANALYSIS; DNA MICROARRAY; DRUG RESISTANCE; FOLLOW UP; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; LUNG NEOPLASMS; LYMPH NODE METASTASIS; METABOLISM; MIDDLE AGED; MORTALITY; MUTATION; PATHOLOGY; PROGNOSIS; SECONDARY; SURVIVAL RATE;

ANTINEOPLASTIC AGENTS, HORMONAL; BIOMARKERS, TUMOR; BREAST NEOPLASMS; CHROMOSOMAL PROTEINS, NON-HISTONE; COHORT STUDIES; DRUG RESISTANCE, NEOPLASM; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MIDDLE AGED; MUTATION; NEOPLASM GRADING; NEOPLASM STAGING; NEOPLASTIC STEM CELLS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RNA, MESSENGER; SURVIVAL RATE; TAMOXIFEN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84911954588     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-3172-7     Document Type: Article

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