Disabled-2 is required for efficient hemostasis and platelet activation by thrombin in mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 11, 2014, Pages 2404-2412

  Tsai, Hui Ju ^a   Huang, Chien Ling ^b   Chang, Yao Wen ^a   Huang, Ding Yuan ^b   Lin, Chung Ching ^b   Cooper, Jonathan A ^c   Cheng, Ju Chien ^d   Tseng, Ching Ping ^a,b,e  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c USA   (United States)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Dab2 protein, mouse; Platelet activation; Thrombin

Indexed keywords

ADENOSINE DIPHOSPHATE; DISABLED 2 PROTEIN; FIBRINOGEN; G ALPHA12 PROTEIN; G ALPHA13 PROTEIN; INTEGRIN ALPHA2BETA3; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN; PROTEIN KINASE B; PROTEIN KINASE C; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; ROCK2 PROTEIN; THROMBIN; THROMBIN RECEPTOR; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; FIBRINOGEN RECEPTOR; MTOR PROTEIN, MOUSE; NOSTRIN PROTEIN, MOUSE; RHO KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; BLEEDING TIME; BLOOD CLOT RETRACTION; CALCIUM MOBILIZATION; CELL LINEAGE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; FIBRINOGEN BLOOD LEVEL; HEMOSTASIS; IN VIVO STUDY; INTRACELLULAR SIGNALING; KNOCKOUT MOUSE; MEGAKARYOCYTE; MOUSE; NONHUMAN; PLASMA PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE ANOMALY; THROMBOCYTE PRESERVATION; THROMBOCYTOPOIESIS; THROMBOSIS; ANIMAL; DEFICIENCY; DISEASE MODEL; GENETICS; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE DIPHOSPHATE; ANIMALS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; HEMOSTASIS; MICE; MICE, KNOCKOUT; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN KINASE C; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; THROMBIN; THROMBOSIS; TOR SERINE-THREONINE KINASES;

EID: 84911944343     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.302602     Document Type: Article

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