Autocrine signaling of platelet-derived growth factor regulates disabled-2 expression during megakaryocytic differentiation of K562 cells

FEBS Letters

Volumn 579, Issue 20, 2005, Pages 4395-4401

  Tseng, Ching Ping ^a   Chang, Pam ^a   Huang, Chien Ling ^a   Cheng, Ju Chien ^b   Chang, Shy Shin ^c  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Disabled 2; Megakaryocytic differentiation; Platelet derived growth factor; STI571

Indexed keywords

ADAPTOR PROTEIN; DISABLED 2 PROTEIN; IMATINIB; MESSENGER RNA; NEUTRALIZING ANTIBODY; PHORBOL 13 ACETATE 12 MYRISTATE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; AUTOCRINE EFFECT; CELL DIFFERENTIATION; CONTROLLED STUDY; CULTURE MEDIUM; HUMAN; HUMAN CELL; MEGAKARYOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; THROMBOCYTE; UPREGULATION; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; AUTOCRINE COMMUNICATION; CELL DIFFERENTIATION; CULTURE MEDIA, CONDITIONED; GENES, TUMOR SUPPRESSOR; HUMANS; K562 CELLS; MEGAKARYOCYTES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PIPERAZINES; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; PYRIMIDINES; THROMBOPOIESIS;

EID: 23644436021     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.06.080     Document Type: Article

References (32)

1. C.H. Heldin, and B. Westermark Mechanism of action and in vivo role of platelet-derived growth factor Physiol. Rev. 79 1999 1283 1316
2. P. Leve'en, M. Pekny, S. Gebre-Medhin, B. Swolin, E. Larsson, and C. Betsholtz Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities Genes Dev. 8 1994 1875 1887
3. P. Soriano Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice Genes Dev. 8 1994 1888 1896
4. R. Alitalo Induced differentiation of K562 leukemia cells: a model for studies of gene expression in early megakaryoblasts Leuk. Res. 14 1990 501 514
5. R. Alitalo, L.C. Andersson, C. Betsholtz, K. Nilsson, B. Westermark, C.H. Heldin, and K. Alitalo Induction of platelet-derived growth factor gene expression during megakaryoblastic and monocytic differentiation of human leukemia cell lines EMBO J. 6 1987 1213 1218
6. F.K. Racke, K. Lewandowska, S. Goueli, and A.N. Goldfarb Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells J. Biol. Chem. 272 1997 23366 23370
7. C.M. Chui, K. Li, M. Yang, C.K. Chuen, T.K. Fok, C.K. Li, and P.M. Yuen Platelet-derived growth factor up-regulates the expression of transcription factors NF-E2, GATA-1 and c-Fos in megakaryocytic cell lines Cytokine 21 2003 51 64
8. X.X. Xu, T. Yi, B. Tang, and J.D. Lambeth Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2 Oncogene 16 1998 1561 1569
9. J. Zhou, and J.T. Hsieh The inhibitory role of DOC-2/DAB2 in growth factor receptor-mediated signal cascade. DOC-2/DAB2-mediated inhibition of ERK phosphorylation via binding to Grb2 J. Biol. Chem. 276 2001 27793 27798
10. S.K. Mishra, P.A. Keyel, M.J. Hawryluk, N.R. Agostinelli, S.C. Watkins, and L.M. Traub Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor EMBO J. 21 2002 4915 4926
11. S.M. Morris, S.D. Arden, R.C. Roberts, J. Kendrick-Jones, J.A. Cooper, J.P. Luzio, and F. Buss Myosin VI binds to and localizes with Dab2, potentially linking receptor-mediated endocytosis and the actin cytoskeleton Traffic 3 2002 331 341
12. S.M. Morris, and J.A. Copper Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2 Traffic 2 2001 111 123
13. C.P. Tseng, C.L. Huang, C.H. Huang, J.C. Cheng, A. Stern, C.H. Tseng, and D.T.Y. Chiu Disabled-2 small interfering RNA modulates cellular adhesive function and MAPK activity during megakaryocytic differentiation of K562 cells FEBS Lett 541 2003 21 27
14. F. Rosenbauer, A. Kallies, M. Scheller, K.P. Knobeloch, C.O. Rock, M. Schwieger, C. Stocking, and I. Horak Disabled-2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion EMBO J. 21 2002 211 220
15. C.L. Huang, J.C. Cheng, C.H. Liao, A. Stern, J.T. Hsieh, C.H. Wang, H.L. Hsu, and C.P. Tseng Disabled-2 is a negative regulator of integrin α IIbβ 3-mediated fibrinogen adhesion and cell signaling J. Biol. Chem. 279 2004 42279 42289
16. C.P. Tseng, C.H. Huang, C.C. Tseng, M.H. Lin, J.T. Hsieh, and C.H. Tseng Induction of Disabled-2 gene during megakaryocyte differentiation of K562 cells Biochem. Biophys. Res. Commun. 285 2001 129 135
17. Y. Akiyama, N. Watkins, H. Suzuki, K.W. Jair, M. van Engeland, M. Esteller, H. Sakai, C.Y. Ren, Y. Yuasa, J.G. Herman, and S.B. Baylin GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer Mol. Cell. Biol. 23 2003 8429 8439
18. E.E. Morrisey, S. Musco, M.Y. Chen, M.M. Lu, J.M. Leiden, and M.S. Parmacek The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm J. Biol. Chem. 275 2000 19949 19954
19. Y. Zhuang, T.N. Faria, P. Chambon, and L.J. Gudas Identification and characterization of retinoic acid receptor beta2 target genes in F9 teratocarinoma cells Mol. Cancer Res. 1 2003 619 630
20. E. Buchdunger, C.L. Cioffi, N. Law, D. Stover, S. Ohno-Jones, B.J. Druker, and N.B. Lydon Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors J. Pharmacol. Exp. Ther. 295 2000 139 145
21. M. Emaduddin, S. Ekman, L. Ronnstrand, and C.H. Heldin Functional co-operation between the subunits in heterodimeric platelet-derived growth factor receptor complexes Biochem. J. 341 1999 523 528
22. Y. Ikuno, and A. Kazlauskas An in vivo gene therapy approach for experimental proliferative vitreoretinopathy using the truncated platelet-derived growth factor alpha receptor Invest. Ophthalmol. Vis. Sci. 43 2002 2406 2411
23. L. Claesson-Welsh Mechanism of action of platelet-derived growth factor Int. J. Biochem. Cell Biol. 28 1996 373 385
24. E.N. Maina, M.R. Morris, M. Zatyka, R.R. Raval, R.E. Banks, F.M. Richards, C.M. Johnson, and E.R. Maher Identification of novel VHL target genes and relationship to hypoxic response pathways Oncogene 24 2005 4549 4558
25. R. Airik, M. Karner, A. Karis, and J. Karner Gene expression analysis of Gata3-/- mice by using cDNA microarray technology Life Sci. 76 2005 2559 2568
26. C.F. Calkhoven, C. Muller, R. Martin, G. Krosl, H. Pietsch, T. Hoang, and A. Leutz Translational control of SCL-isoform expression in hematopoietic lineage choice Genes Dev. 17 2003 959 964
27. A. Pozner, D. Goldenberg, V. Negreanu, S.Y. Le, O. Elroy-Stein, D. Levanon, and Y. Groner Transcription-coupled translation control of AML1/RUNX1 is mediated by cap- and internal ribosome entry site-dependent mechanisms Mol. Cell. Biol. 20 2000 2297 2307
28. M. Duquette, and O. Laneuville Translational regulation of prostaglandin endoperoxide H synthase-1 mRNA in megakaryocytic MEG-01 cells. Specific protein binding to a conserved 20-nucleotide CIS element in the 3′-untranslated region J. Biol. Chem. 277 2002 44631 44637
29. D.H. Mathews, J. Sabina, M. Zuker, and D.H. Turner Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure J. Mol. Biol. 288 1999 911 940
30. S. Appel, A.M. Boehmler, F. Grunebach, M.R. Muller, A. Rupf, M.M. Weck, U. Hartmann, V.L. Reichardt, L. Kanz, T.H. Brummendorf, and P. Brossart Imatinib mesylate affects the development and function of dendritic cells generated from CD34+ peripheral blood progenitor cells Blood 103 2004 538 544
31. A.L. Dewar, R.M. Domaschenz, K.V. Doherty, T.P. Hughes, and A.B. Lyons Imatinib inhibits the in vitro development of the monocyte/macrophage lineage from normal human bone marrow progenitors Leukemia 17 2003 1713 1721
32. M. Yang, C.N. Chesterman, and B.H. Chong Recombinant PDGF enhances megakaryocytopoiesis in vitro Br. J. Haematol. 91 1995 285 289