DOC-2/DAB2 is the binding partner of myosin VI

Biochemical and Biophysical Research Communications

Volumn 292, Issue 2, 2002, Pages 300-307

  Inoue, Akira ^a   Sato, Osamu ^a   Homma, Kazuaki ^a   Ikebe, Mitsuo ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Actin; ATPase; DOC 2 DAB2; Molecular motor; Myosin VI; Rab2; Ras; Trafficking; Vesicle transport

Indexed keywords

ACTIN; AMINO ACID; ISOPROTEIN; MYOSIN; MYOSIN HEAVY CHAIN; MYOSIN VI; PROTEIN DAB2; PROTEIN DOC 2; RAS PROTEIN; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ACTIN FILAMENT; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING ASSAY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STOICHIOMETRY;

EID: 0036295583     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6636     Document Type: Article

References (38)

1. Unconventional myosins
2. Unconventional myosins: New frontiers in actin-based motors
3. A myosin family tree
4. Porcine myosin VI: Characterization of a new mammalian unconventional myosin
5. The mouse Snell's walzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells
6. The localization of myosin VI at the Golgi complex and leading edge of fibroblast and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation
7. Structure of the actin-myosin complex and its implications for muscle contraction
8. Three-dimensional structure of myosin subfragment-1: A molecular motor
9. Going mobile: Microtubule motors and chromosome segregation
10. Kinesin and dynein superfamily proteins and the mechanism of organelle transport
11. Myosin V is a processive actin based motor
12. Direct observation of processive movement by individual myosin V molecules
13. Myosin V associates with melanosomes in mouse melanocytes: Evidence that myosin V is an organelle motor
14. Regulation of melanosome movement in the cell cycle by reversible association with myosin V
15. Myosin V plays an essential role in the thyroid hormone-dependent endocytosis of type II iodothyronine 5′-deiodinase
16. Myosin VI is a processive motor with a large step size
17. Class VI myosin moves processively along actin filaments backward with large steps
18. Transport of cytoplasmic particles catalyzed by an unconventional myosin in Drosophila embryos
19. Drosophila unconventional myosin VI is involved in intra and intercellular transport during oogenesis
20. 2+-dependent interaction with the synaptobrevin-synaptophysin complex
21. Molecular cloning and characterization of neural activity-related RING finger protein (NARF): A new member of the RBCC family is a candidate for the partner of myosin V
22. The regulation of rabbit skeletal muscle contraction. 1. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin
23. Dual regulation of mammalian myosin VI motor function
24. Functional expression of mammalian myosin Ib: Analysis of its motor activity
25. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
26. The correlation of reaction kinetics and substrate binding with the mechanism of pyruvate kinase
27. Inhibition of conformational change in smooth muscle myosin by a monoclonal antibody against 17-kDa light chain
28. Characterization of the motor and enzymatic activities of smooth muscle long S1 and short HMM: Role of the two headed structure on the regulation
29. Molecular cloning of differentially expressed genes in human epithelial ovarian cancer
30. DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer
31. Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2
32. The SH2 and SH3 domain-containing protein GRB2 link receptor tyrosine kinase to ras signaling
33. The inhibitory role of DOC-2/DAB2 in growth factor receptor-mediated signal transduction
34. Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis
35. Involvement of myosin VI in endocytic pathways