Structure, sulfatide binding properties, and inhibition of platelet aggregation by a disabled-2 protein-derived peptide

Journal of Biological Chemistry

Volumn 287, Issue 45, 2012, Pages 37691-37702

  Xiao, Shuyan ^a   Charonko, John J ^b   Fu, Xiangping ^c   Salmanzadeh, Alireza ^d   Davalos, Rafael V ^d   Vlachos, Pavlos P ^b   Finkielstein, Carla V ^c   Capelluto, Daniel G S ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b Advanced Experimental Thermofluidics Engineering Research Laboratory   (United States)

^c Department of Biological Sciences   (United States)

^d Medical Center Boulevard   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPATHIC; BINDING PROPERTIES; INHIBITION OF PLATELET AGGREGATION; PLATELET AGGREGATION;

BINDING ENERGY; PEPTIDES;

PLATELETS;

DISABLED 2 PROTEIN; MEMBRANE PROTEIN; SULFATIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL INTERACTION; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIPID ANALYSIS; MICELLE; MOLECULAR DYNAMICS; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; THROMBOCYTE AGGREGATION INHIBITION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; CIRCULAR DICHROISM; HUMANS; MICELLES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOSPHORYLCHOLINE; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SULFOGLYCOSPHINGOLIPIDS; SURFACE PLASMON RESONANCE; TUMOR SUPPRESSOR PROTEINS;

EID: 84868332268     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.385609     Document Type: Article

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