Prenatal exposure to phthalate ester and pubertal development in a birth cohort in central Taiwan: A 12-year follow-up study

Environmental Research

Volumn 136, Issue , 2015, Pages 324-330

  Su, Pen Hua ^a,b   Chang, Chin Kuo ^c   Lin, Ching Yi ^a,b   Chen, Hsiao Yen ^d   Liao, Pao Chi ^e   Hsiung, Chao A ^d   Chiang, Hung Che ^d   Wang, Shu Li ^d,f,g  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^e NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^f NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^g CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID ESTER; PHTHALIC ACID MONO (2 ETHYL 5 HYDROXYHEXYL) ESTER; PHTHALIC ACID MONO (2 ETHYL 5 OXOHEXYL) ESTER; PHTHALIC ACID MONOBENZYL ESTER; PHTHALIC ACID MONOBUTYL ESTER; PHTHALIC ACID MONOETHYL ESTER; PHTHALIC ACID MONOMETHYL ESTER; UNCLASSIFIED DRUG; ESTER; PHTHALIC ACID;

BIRTH RATE; COHORT ANALYSIS; ESTER; MATERNAL HEALTH; POLLUTION EXPOSURE; REPRODUCTIVE BIOLOGY; URINE;

ARTICLE; BONE AGE; CHILD; COHORT ANALYSIS; ENVIRONMENTAL EXPOSURE; FEMALE; FOLLOW UP; HUMAN; KIDNEY CONCENTRATING CAPACITY; LIQUID CHROMATOGRAPHY; MALE; METABOLITE; NORMAL HUMAN; ORGAN SIZE; OUTCOME ASSESSMENT; OVARY; PHYSICAL EXAMINATION; PREGNANCY; PRENATAL EXPOSURE; PUBERTY; TAIWAN; TANDEM MASS SPECTROMETRY; TESTIS SIZE; THIRD TRIMESTER PREGNANCY; UTERUS; CHEMISTRY; DRUG EFFECTS; SEXUAL MATURATION; TOXICITY;

TAIWAN;

CHILD; CHROMATOGRAPHY, LIQUID; COHORT STUDIES; ESTERS; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; PHTHALIC ACIDS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; SEXUAL MATURATION; TAIWAN; TANDEM MASS SPECTROMETRY;

EID: 84911912309     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2014.10.026     Document Type: Article

References (33)

1. Badouraki M., Christoforidis A., Economou I., Dimitriadis A.S., Katzos G. Evaluation of pelvic ultrasonography in the diagnosis and differentiation of various forms of sexual precocity in girls. Ultrasound Obstet. Gynecol. 2008, 32:819-827.
2. Braun J.M., Smith K.W., Williams P.L., Calafat A.M., Berry K., Ehrlich S., Hauser R. Variability of urinary phthalate metabolite and bisphenol A concentrations before and during pregnancy. Environ. Health Perspect. 2012, 120:739-745.
3. Bustamante-Montes L.P., Hernandez-Valero M.A., Flores-Pimentel D., Garcia-Fabila M., Amaya-Chavez A., Barr D.B., Borja-Aburto V.H. Prenatal exposure to phthalates is associated with decreased anogenital distance and penile size in male newborns. J. Dev. Orig. Health Dis 2013, 4:300-306.
4. Colon I., Caro D., Bourdony C.J., Rosario O. Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development. Environ. Health Perspect. 2000, 108:895-900.
5. Frederiksen H., Sorensen K., Mouritsen A., Aksglaede L., Hagen C.P., Petersen J.H., Skakkebaek N.E., Andersson A.M., Juul A. High urinary phthalate concentration associated with delayed pubarche in girls. Int. J. Androl. 2012, 35:216-226.
6. Green R., Hauser R., Calafat A.M., Weuve J., Schettler T., Ringer S., Huttner K., Hu H. Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants. Environ. Health Perspect. 2005, 113:1222-1225.
7. Greulich W.W., Pyle S.I. Radiographic Altas of Skeletal Development of the Hand and Wrist 1959, Stanford University Press, Stanford, CA, USA. 2nd ed.
8. Hart R., Doherty D.A., Frederiksen H., Keelan J.A., Hickey M., Sloboda D., Pennell C.E., Newnham J.P., Skakkebaek N.E., Main K.M. The influence of antenatal exposure to phthalates on subsequent female reproductive development in adolescence: a pilot study. Reproduction 2014, 147:379-390.
9. Huang P.C., Kuo P.L., Chou Y.Y., Lin S.J., Lee C.C. Association between prenatal exposure to phthalates and the health of newborns. Environ. Int. 2009, 35:14-20.
10. Kay V.R., Chambers C., Foster W.G. Reproductive and developmental effects of phthalate diesters in females. Crit. Rev. Toxicol. 2013, 43:200-219.
11. Koch H.M., Gonzalez-Reche L.M., Angerer J. On-line clean-up by multidimensional liquid chromatography-electrospray ionization tandem mass spectrometry for high throughput quantification of primary and secondary phthalate metabolites in human urine. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2003, 784:169-182.
12. Lin L.C., Wang S.L., Chang Y.C., Huang P.C., Cheng J.T., Su P.H., Liao P.C. Associations between maternal phthalate exposure and cord sex hormones in human infants. Chemosphere 2011, 83:1192-1199.
13. Lin S., Ku H.Y., Su P.H., Chen J.W., Huang P.C., Angerer J., Wang S.L. Phthalate exposure in pregnant women and their children in central Taiwan. Chemosphere 2011, 82:947-955.
14. Marshall W.A., Tanner J.M. Variations in pattern of pubertal changes in girls. Arch. Dis. Child. 1969, 44:291-303.
15. Martinez-Arguelles D.B., Campioli E., Culty M., Zirkin B.R., Papadopoulos V. Fetal origin of endocrine dysfunction in the adult: the phthalate model. J. Steroid Biochem. Mol. Biol. 2013, 137:5-17.
16. Martino-Andrade A.J., Chahoud I. Reproductive toxicity of phthalate esters. Mol. Nutr. Food Res. 2010, 54:148-157.
17. Moyer B., Hixon M.L. Reproductive effects in F1 adult females exposed in utero to moderate to high doses of mono-2-ethylhexylphthalate (MEHP). Reprod. Toxicol. 2012, 34:43-50.
18. Noriega N.C., Howdeshell K.L., Furr J., Lambright C.R., Wilson V.S., Gray L.E. Pubertal administration of DEHP delays puberty, suppresses testosterone production, and inhibits reproductive tract development in male Sprague-Dawley and Long-Evans rats. Toxicol. Sci. 2009, 111:163-178.
19. Parks L.G., Ostby J.S., Lambright C.R., Abbott B.D., Klinefelter G.R., Barlow N.J., Gray L.E. The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat. Toxicol. Sci. 2000, 58:339-349.
20. Prader A. Testicular size: assessment and clinical importance. Triangle 1966, 7:240-243.
21. Preuss R., Koch H.M., Angerer J. Biological monitoring of the five major metabolites of di-(2-ethylhexyl)phthalate (DEHP) in human urine using column-switching liquid chromatography-tandem mass spectrometry. J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2005, 816:269-280.
22. Roy J.R., Chakraborty S., Chakraborty T.R. Estrogen-like endocrine disrupting chemicals affecting puberty in humans - a review. Med. Sci. Monit. 2009, 15:RA137-RA145.
23. Sanfilippo J.S., Jamieson M.A. Physiology of Puberty. Reproductive Endocrinology, Infertility, and Genetics. Gynecology & Obstetrics 2004, 5. Lippincott Williams & Wilkins, Philadelphia, PA, USA, Chapter 9.
24. Schettler T. Human exposure to phthalates via consumer products. Int. J. Androl. 2006, 29:134-139. (discussion 181-135).
25. Su P.H., Chang Y.Z., Chang H.P., Wang S.L., Haung H.I., Huang P.C., Chen J.Y. Exposure to di(2-ethylhexyl) phthalate in premature neonates in a neonatal intensive care unit in Taiwan. Pediatr. Crit. Care Med. 2012, 13:671-677.
26. Su P.H., Huang P.C., Lin C.Y., Ying T.H., Chen J.Y., Wang S.L. The effect of in utero exposure to dioxins and polychlorinated biphenyls on reproductive development in eight year-old children. Environ. Int. 2012, 39:181-187.
27. Suzuki Y., Yoshinaga J., Mizumoto Y., Serizawa S., Shiraishi H. Foetal exposure to phthalate esters and anogenital distance in male newborns. Int. J. Androl. 2012, 35:236-244.
28. Swan S.H., Main K.M., Liu F., Stewart S.L., Kruse R.L., Calafat A.M., Mao C.S., Redmon J.B., Ternand C.L., Sullivan S., Teague J.L. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ. Health Perspect. 2005, 113:1056-1061.
29. Tanner J.M. Growth at Aldolescence 1962, Blackwell Scientific Publications, Oxford, England. 2nd ed.
30. Veeramachaneni D.N., Klinefelter G.R. Phthalate-induced pathology in the foetal testis involves more than decreased testosterone production. Reproduction 2014, 147:435-442.
31. Wolff M.S., Teitelbaum S.L., McGovern K., Windham G.C., Pinney S.M., Galvez M., Calafat A.M., Kushi L.H., Biro F.M. Phthalate exposure and pubertal development in a longitudinal study of US girls. Hum. Reprod. 2014, 29:1558-1566.
32. Wittassek M., Koch H.M., Angerer J., Bruning T. Assessing exposure to phthalates-the human biomonitoring approach. Mol. Nutr. Food Res. 2011, 55:7-31.
33. Zeger S.L., Liang K.Y. Longitudinal data analysis for discrete and continuous outcomes. Biometrics 1986, 42:121-130.