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Journal of Molecular Catalysis B: Enzymatic

Volumn 110, Issue , 2014, Pages 154-164

Unraveling the multispecificity and catalytic promiscuity of taxadiene monooxygenase

(1) Yadav, Vikramaditya G a,b,c

a Massachusetts Institute of Technology (United States)

b HARVARD UNIVERSITY (United States)

c UNIVERSITY OF BRITISH COLUMBIA (Canada)

Author keywords

Catalytic promiscuity; Computational biochemistry; Cytochrome P450 monooxygenase; Multispecificity; Taxane oxidation

Indexed keywords

CATALYTIC OXIDATION; ENZYMES; ESCHERICHIA COLI; HYDROGELS; METABOLIC ENGINEERING; METABOLISM; METABOLITES;

CATALYTIC MECHANISMS; CATALYTIC PROMISCUITY; COMPUTATIONAL ANALYSIS; COMPUTATIONAL BIOCHEMISTRIES; COMPUTATIONAL METHODOLOGY; MONOOXYGENASES; MULTISPECIFICITY; PLANT SECONDARY METABOLITES;

BIOCHEMICAL ENGINEERING;

TAXADIENE 5 ALPHA HYDROXYLASE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME ENGINEERING; ENZYME SPECIFICITY; ENZYME SUBSTRATE; METABOLIC ENGINEERING; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; STEREOSPECIFICITY; X RAY CRYSTALLOGRAPHY;

EID: 84911886445 PISSN: 13811177 EISSN: 18733158 Source Type: Journal
DOI: 10.1016/j.molcatb.2014.10.004 Document Type: Article

Times cited : (20)

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