α-Ketoglutaramate: an overlooked metabolite of glutamine and a biomarker for hepatic encephalopathy and inborn errors of the urea cycle

Metabolic Brain Disease

Volumn 29, Issue 4, 2014, Pages 991-1006

  Cooper, Arthur J L ^a   Kuhara, Tomiko ^b,c  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b KANAZAWA MEDICAL UNIVERSITY   (Japan)

^c Japan Clinical Metabolomics Institute   (Japan)

Author keywords

Ammonia; Glutaminase II; Hepatic encephalopathy; Urea cycle disorders; ketoglutaramate; Amidase

Indexed keywords

2 OXOGLUTARIC ACID; ALPHA-KETOGLUTARAMATE; AMIDASE; AMINOTRANSFERASE; AMMONIA; BIOLOGICAL MARKER; CARBON; GLUTAMINE; GLUTAMINE-PYRUVATE AMINOTRANSFERASE; HYDROLASE; KYNURENINE; KYNURENINE-OXOGLUTARATE TRANSAMINASE; METHIONINE; NITRILASE; NITROGEN; OMEGA-AMIDASE; OXOACID; SULFUR;

ANIMAL; CEREBROSPINAL FLUID; CLASSIFICATION; HEPATIC ENCEPHALOPATHY; HUMAN; HYPERAMMONEMIA; LIVER DISEASE; MAMMAL; METABOLISM; PHYSIOLOGY; UREA CYCLE DISORDER; URINE;

AMIDOHYDROLASES; AMINOHYDROLASES; AMMONIA; ANIMALS; BIOMARKERS; CARBON; GLUTAMINE; HEPATIC ENCEPHALOPATHY; HUMANS; HYPERAMMONEMIA; KETO ACIDS; KETOGLUTARIC ACIDS; KYNURENINE; LIVER DISEASES; MAMMALS; METHIONINE; NITROGEN; SULFUR; TRANSAMINASES; UREA CYCLE DISORDERS, INBORN;

EID: 84911808428     PISSN: 08857490     EISSN: 15737365     Source Type: Journal    
DOI: 10.1007/s11011-013-9444-9     Document Type: Article

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