Malaria vaccine candidate antigen targeting the pre-erythrocytic stage of Plasmodium falciparum produced at high level in plants

Biotechnology Journal

Volumn 9, Issue 11, 2014, Pages 1435-1445

  Voepel, Nadja ^a   Boes, Alexander ^a   Edgue, Güven ^a   Beiss, Veronique ^a   Kapelski, Stephanie ^a   Reimann, Andreas ^a   Schillberg, Stefan ^a   Pradel, Gabriele ^b   Fendel, Rolf ^a   Scheuermayer, Matthias ^c   Spiegel, Holger ^a   Fischer, Rainer ^a,b  

^a FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Agroinfiltration; Host cell protein removal; Multidomain antigen; Nicotiana benthamiana; Plant molecular farming

Indexed keywords

ADHESIVES; ANTIGENS; COSTS; PLANTS (BOTANY); PROTEINS; PURIFICATION; VACCINES;

AGROINFILTRATION; HOST CELL PROTEIN; MOLECULAR FARMING; MULTI DOMAINS; NICOTIANA BENTHAMIANA;

DISEASES;

CCT FUSION PROTEIN; HYBRID PROTEIN; IMMUNOGLOBULIN G; MALARIA VACCINE; PEPTIDES AND PROTEINS; PLASMODIUM FALCIPARUM CELL TRAVERSAL PROTEIN FOR OOKINETES AND SPOROZOITES; PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE PROTEIN; PLASMODIUM FALCIPARUM THROMBOSPONDIN RELATED ADHESIVE PROTEIN; UNCLASSIFIED DRUG; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY;

ADULT; AGROBACTERIUM TUMEFACIENS; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CELL INVASION; CONFORMATION; CONTROLLED STUDY; DRUG PURIFICATION; HUMAN; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; LIVER CELL; MOUSE; NICOTIANA BENTHAMIANA; NONHUMAN; PLANT LEAF; PLASMODIUM (LIFE CYCLE STAGE); PLASMODIUM FALCIPARUM; VACCINE PRODUCTION; ANIMAL; BLOOD; CHEMISTRY; GENETICS; HEAT; IMMUNOLOGY; MALARIA FALCIPARUM; METABOLISM; PARASITOLOGY; SPOROZOITE; TOBACCO; TRANSGENIC PLANT;

NICOTIANA BENTHAMIANA; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIBODIES, PROTOZOAN; HOT TEMPERATURE; HUMANS; MALARIA VACCINES; MALARIA, FALCIPARUM; MICE; PLANT LEAVES; PLANTS, GENETICALLY MODIFIED; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RECOMBINANT FUSION PROTEINS; SPOROZOITES; TOBACCO;

EID: 84911486867     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201400350     Document Type: Article

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