메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

Plant-based production of recombinant plasmodium surface protein Pf38 and evaluation of its potential as a vaccine candidate

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; IMMUNOGLOBULIN G; MALARIA VACCINE; RECOMBINANT PLASMODIUM SURFACE PROTEIN PF38; UNCLASSIFIED DRUG;

EID: 84896722103     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079920     Document Type: Article
Times cited : (33)

References (48)
  • 1
    • 84856408211 scopus 로고    scopus 로고
    • Available: Accessed 2013 October 31
    • World Health Organisation. (2011) World malaria report. Available: http://www.who.int/malaria/world-malaria-report-2011/en/. Accessed 2013 October 31.
    • (2011) World Malaria Report
  • 2
    • 70350004832 scopus 로고    scopus 로고
    • Impact of the large-scale deployment of artemether/lumefantrine on the malaria disease burden in Africa: Case studies of South Africa, Zambia and Ethiopia
    • Barnes KI, Chanda P, Ab Barnabas G (2009) Impact of the large-scale deployment of artemether/lumefantrine on the malaria disease burden in Africa: case studies of South Africa, Zambia and Ethiopia. Malar J 8 Suppl 1: S8.
    • (2009) Malar J , vol.8 , Issue.SUPPL. 1
    • Barnes, K.I.1    Chanda, P.2    Ab Barnabas, G.3
  • 4
    • 77956831730 scopus 로고    scopus 로고
    • Reducing Plasmodium falciparum Malaria transmission in Africa: A model-based evaluation of intervention strategies
    • Griffin JT, Hollingsworth TD, Okell LC, Churcher TS, White M, et al. (2010) Reducing Plasmodium falciparum Malaria transmission in Africa: A model-based evaluation of intervention strategies. PLoS Med 7: e1000324.
    • (2010) PLoS Med , vol.7
    • Griffin, J.T.1    Hollingsworth, T.D.2    Okell, L.C.3    Churcher, T.S.4    White, M.5
  • 5
    • 77955027421 scopus 로고    scopus 로고
    • Estimating the global clinical burden of Plasmodium falciparum malaria in 2007
    • Hay SI, Okiro EA, Gething PW, Patil AP, Tatem AJ, et al. (2010) Estimating the global clinical burden of Plasmodium falciparum malaria in 2007. PLoS Med 7: e1000290.
    • (2010) PLoS Med , vol.7
    • Hay, S.I.1    Okiro, E.A.2    Gething, P.W.3    Patil, A.P.4    Tatem, A.J.5
  • 6
    • 77957985070 scopus 로고    scopus 로고
    • Pyrethroid resistance in African anopheline mosquitoes: What are the implications for malaria control?
    • Ranson H, N'Guessan R, Lines J, Moiroux N, Nkuni Z, et al. (2011) Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control? Trends Parasitol 27: 91-98.
    • (2011) Trends Parasitol , vol.27 , pp. 91-98
    • Ranson, H.1    N'Guessan, R.2    Lines, J.3    Moiroux, N.4    Nkuni, Z.5
  • 7
    • 0343204568 scopus 로고
    • Active immunization of fowls against Plasmodium gallinaceum by injections of killed homologous sporozoites
    • Mulligan HW, Russell PF, Mohan BN (1941) Active immunization of fowls against Plasmodium gallinaceum by injections of killed homologous sporozoites. Jour Malaria Inst India 4: 25-34.
    • (1941) Jour Malaria Inst India , vol.4 , pp. 25-34
    • Mulligan, H.W.1    Russell, P.F.2    Mohan, B.N.3
  • 8
    • 45949093410 scopus 로고    scopus 로고
    • Malaria vaccines: A toy for travelers or a tool for eradication?
    • Genton B (2008) Malaria vaccines: a toy for travelers or a tool for eradication? Expert Rev Vaccines 7: 597-611.
    • (2008) Expert Rev Vaccines , vol.7 , pp. 597-611
    • Genton, B.1
  • 9
    • 68949126822 scopus 로고    scopus 로고
    • Do we still need a malaria vaccine?
    • Greenwood B, Targett G (2009) Do we still need a malaria vaccine? Parasite Immunol 31: 582-586.
    • (2009) Parasite Immunol , vol.31 , pp. 582-586
    • Greenwood, B.1    Targett, G.2
  • 10
    • 78650471456 scopus 로고    scopus 로고
    • Is vaccine the magic bullet for malaria elimination? A reality check
    • Chilengi R, Gitaka J (2010) Is vaccine the magic bullet for malaria elimination? A reality check. Malar J 9 Suppl 3: S1.
    • (2010) Malar J , vol.9 , Issue.SUPPL. 3
    • Chilengi, R.1    Gitaka, J.2
  • 11
    • 78649838978 scopus 로고    scopus 로고
    • Advances and challenges in malaria vaccine development
    • Crompton PD, Pierce SK, Miller LH (2010) Advances and challenges in malaria vaccine development. J Clin Invest 120: 4168-4178.
    • (2010) J Clin Invest , vol.120 , pp. 4168-4178
    • Crompton, P.D.1    Pierce, S.K.2    Miller, L.H.3
  • 13
    • 84871037616 scopus 로고    scopus 로고
    • A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants
    • The RTS,S Clinical Trials Partnership DOI: 10.1056/ NEJMoa1208394
    • The RTS,S Clinical Trials Partnership (2012) A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants. N Engl J Med: DOI: 10.1056/ NEJMoa1208394.
    • (2012) N Engl J Med
  • 15
    • 33746273843 scopus 로고    scopus 로고
    • Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum
    • DOI 10.1074/mcp.M600035-MCP200
    • Gilson PR, Nebl T, Vukcevic D, Moritz RL, Sargeant T, et al. (2006) Identification and stoichiometry of glycosylphosphatidylinositol-anchored membrane proteins of the human malaria parasite Plasmodium falciparum. Mol Cell Proteomics 5: 1286-1299. (Pubitemid 44103399)
    • (2006) Molecular and Cellular Proteomics , vol.5 , Issue.7 , pp. 1286-1299
    • Gilson, P.R.1    Nebl, T.2    Vukcevic, D.3    Moritz, R.L.4    Sargeant, T.5    Speed, T.P.6    Schofield, L.7    Crabb, B.S.8
  • 16
    • 0029027446 scopus 로고
    • Predicted disulfide-bonded structures for three uniquely related proteins of Plasmodium falciparum, Pfs230, Pfs48/45 and Pf12
    • Carter R, Coulson A, Bhatti S, Taylor BJ, Elliot JF (1995) Predicted disulfide-bonded structures for three uniquely related proteins of Plasmodium falciparum, Pfs230, Pfs48/45 and Pf12. Mol Biochem Parasitol 71: 203-210.
    • (1995) Mol Biochem Parasitol , vol.71 , pp. 203-210
    • Carter, R.1    Coulson, A.2    Bhatti, S.3    Taylor, B.J.4    Elliot, J.F.5
  • 17
    • 67349215705 scopus 로고    scopus 로고
    • Identification of conserved erythrocyte binding regions in members of the Plasmodium falciparum Cys6 lipid raft-associated protein family
    • Garcia J, Curtidor H, Pinzon CG, Vanegas M, Moreno A, et al. (2009) Identification of conserved erythrocyte binding regions in members of the Plasmodium falciparum Cys6 lipid raft-associated protein family. Vaccine 27: 3953-3962.
    • (2009) Vaccine , vol.27 , pp. 3953-3962
    • Garcia, J.1    Curtidor, H.2    Pinzon, C.G.3    Vanegas, M.4    Moreno, A.5
  • 18
    • 84455194899 scopus 로고    scopus 로고
    • The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody
    • DOI:10.1038/ncomms1615
    • Douglas AD, Williams AR, Illingworth JJ, Kamuyu SB, Goodman AL, et al. (2012) The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody. Nat Commun: DOI:10.1038/ncomms1615.
    • (2012) Nat Commun
    • Douglas, A.D.1    Williams, A.R.2    Illingworth, J.J.3    Kamuyu, S.B.4    Goodman, A.L.5
  • 19
  • 20
    • 79955870628 scopus 로고    scopus 로고
    • Population genetic analysis of the Plasmodium falciparum 6-cys protein Pf38 in Papua New Guinea reveals domain-specific balancing selection
    • Reeder JC, Wapling J, Mueller I, Siba PM, Barry AE (2011) Population genetic analysis of the Plasmodium falciparum 6-cys protein Pf38 in Papua New Guinea reveals domain-specific balancing selection. Malar J 10: 126.
    • (2011) Malar J , vol.10 , pp. 126
    • Reeder, J.C.1    Wapling, J.2    Mueller, I.3    Siba, P.M.4    Barry, A.E.5
  • 21
    • 84862908922 scopus 로고    scopus 로고
    • Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity
    • Farrance CE, Chichester JA, Musiychuk K, Shamloul M, Rhee A, et al. (2011) Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity. Hum Vaccin 7: 191-198.
    • (2011) Hum Vaccin , vol.7 , pp. 191-198
    • Farrance, C.E.1    Chichester, J.A.2    Musiychuk, K.3    Shamloul, M.4    Rhee, A.5
  • 22
    • 84864948329 scopus 로고    scopus 로고
    • Overview of plant-made vaccine antigens against malaria
    • doi: 10.1155/2012/206918
    • Clemente M, Corigliano MG (2012) Overview of plant-made vaccine antigens against malaria. J Biomed Biotechnol, doi: 10.1155/2012/206918.
    • (2012) J Biomed Biotechnol
    • Clemente, M.1    Corigliano, M.G.2
  • 23
    • 34248172560 scopus 로고    scopus 로고
    • Optimization of human papillomavirus type 16 (HPV-16) L1 expression in plants: Comparison of the suitability of different HPV-16 L1 gene variants and different cell-compartment localization
    • DOI 10.1099/vir.0.82718-0
    • Maclean J, Koekemoer M, Olivier AJ, Stewart D, Hitzeroth II, et al. (2007) Optimization of human papillomavirus type 16 (hpv-16) l1 expression in plants: Comparison of the suitability of different hpv-16 l1 gene variants and different cell-compartment localization. J Gen Virol 88: 1460-1469. (Pubitemid 46723227)
    • (2007) Journal of General Virology , vol.88 , Issue.5 , pp. 1460-1469
    • Maclean, J.1    Koekemoer, M.2    Olivier, A.J.3    Stewart, D.4    Hitzeroth, I.I.5    Rademacher, T.6    Fischer, R.7    Williamson, A.-L.8    Rybicki, E.P.9
  • 24
    • 63449122293 scopus 로고    scopus 로고
    • Functional analysis of the leading malaria vaccine candidate AMA-1 reveals an essential role for the cytoplasmic domain in the invasion process
    • Treeck M, Zacherl S, Herrmann S, Cabrera A, Kono M, et al. (2009) Functional analysis of the leading malaria vaccine candidate AMA-1 reveals an essential role for the cytoplasmic domain in the invasion process. PLoS Pathog 5: e1000322.
    • (2009) PLoS Pathog , vol.5
    • Treeck, M.1    Zacherl, S.2    Herrmann, S.3    Cabrera, A.4    Kono, M.5
  • 25
    • 65549122945 scopus 로고    scopus 로고
    • Transient co-expression for fast and high-yield production of antibodies with human-like n-glycans in plants
    • Vézina LP, Faye L, Lerouge P, D'aoust MA, Marquet-Blouin E, et al. (2009) Transient co-expression for fast and high-yield production of antibodies with human-like n-glycans in plants. Plant Biotechnol J 7: 442-455.
    • (2009) Plant Biotechnol J , vol.7 , pp. 442-455
    • Vézina, L.P.1    Faye, L.2    Lerouge, P.3    D'Aoust, M.A.4    Marquet-Blouin, E.5
  • 26
    • 14744299022 scopus 로고    scopus 로고
    • Opportunities for recombinant antigen and antibody expression in transgenic plants - Technology assessment
    • DOI 10.1016/j.vaccine.2004.11.002
    • Schillberg S, Twyman RM, Fischer R (2005) Opportunities for recombinant antigen and antibody expression in transgenic plants - technology assessment. Vaccine 23: 1764-1769. (Pubitemid 40331841)
    • (2005) Vaccine , vol.23 , Issue.15 SPEC. ISS. , pp. 1764-1769
    • Schillberg, S.1    Twyman, R.M.2    Fischer, R.3
  • 27
    • 0033667765 scopus 로고    scopus 로고
    • Molecular farming of pharmaceutical proteins
    • Fischer R, Emans N (2000) Molecular farming of pharmaceutical proteins. Transgenic Res 9: 279-299.
    • (2000) Transgenic Res , vol.9 , pp. 279-299
    • Fischer, R.1    Emans, N.2
  • 28
    • 37749007243 scopus 로고    scopus 로고
    • HIRecombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans
    • Rademacher T, Sack M, Arcalis E, Stadlmann J, Balzer S, et al. (2008)HIRecombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GlcNAc N-glycans. Plant Biotechnol J 6: 189-201.
    • (2008) Plant Biotechnol J , vol.6 , pp. 189-201
    • Rademacher, T.1    Sack, M.2    Arcalis, E.3    Stadlmann, J.4    Balzer, S.5
  • 29
    • 84865726152 scopus 로고    scopus 로고
    • Monoclonal tobacco cell lines with enhanced recombinant protein yields can be generated from heterogeneous cell suspension cultures by flow sorting
    • Kirchhoff J, Raven N, Boes A, Roberts J, Russell S, et al. (2012) Monoclonal tobacco cell lines with enhanced recombinant protein yields can be generated from heterogeneous cell suspension cultures by flow sorting. Plant Biotechnol J 10: 936-944.
    • (2012) Plant Biotechnol J , vol.10 , pp. 936-944
    • Kirchhoff, J.1    Raven, N.2    Boes, A.3    Roberts, J.4    Russell, S.5
  • 30
    • 84896707009 scopus 로고    scopus 로고
    • Available: Accessed 2013 October 31
    • The IEDB Analysis Resource. (2011) Available: http://tools.immuneepitope. org/analyze/html/mhc-II-binding.html. Accessed 2013 October 31.
    • (2011) The IEDB Analysis Resource
  • 31
    • 0030857850 scopus 로고    scopus 로고
    • Complement-mediated lysis of Plasmodium falciparum gametes by malaria- immune human sera is associated with antibodies to the gamete surface antigen Pfs230
    • Healer J, Mcguinness D, Hopcroft P, Haley S, Carter R, et al. (1997) Complement-mediated lysis of Plasmodium falciparum gametes by malaria-immune human sera is associated with antibodies to the gamete surface antigen pfs230. Infect Immun 65: 3017-3023. (Pubitemid 27342372)
    • (1997) Infection and Immunity , vol.65 , Issue.8 , pp. 3017-3023
    • Healer, J.1    McGuinness, D.2    Hopcroft, P.3    Haley, S.4    Carter, R.5    Riley, E.6
  • 32
    • 77950053031 scopus 로고    scopus 로고
    • Erythrocyte invasion and functionally inhibitory antibodies in Plasmodium falciparum malaria
    • Persson K (2010) Erythrocyte invasion and functionally inhibitory antibodies in Plasmodium falciparum malaria. Acta trop 114: 138-143.
    • (2010) Acta Trop , vol.114 , pp. 138-143
    • Persson, K.1
  • 33
    • 0001200134 scopus 로고
    • The promoter of tl-DNA gene 5 controls the tissue-specific expression of chimeric genes carried by a novel type of agrobacterium binary vector
    • Koncz C, Schell J (1986) The promoter of tl-DNA gene 5 controls the tissue-specific expression of chimeric genes carried by a novel type of agrobacterium binary vector. Mol Genet Genomics 204: 383-396.
    • (1986) Mol Genet Genomics , vol.204 , pp. 383-396
    • Koncz, C.1    Schell, J.2
  • 35
    • 68849097943 scopus 로고    scopus 로고
    • pEAQ: Versatile expression vectors for easy and quick transient expression of heterologous proteins in plants
    • Sainsbury F, Thuenemann EC, Lomonossoff GP (2009) pEAQ: versatile expression vectors for easy and quick transient expression of heterologous proteins in plants. Plant Biotechnol J 7: 682-693.
    • (2009) Plant Biotechnol J , vol.7 , pp. 682-693
    • Sainsbury, F.1    Thuenemann, E.C.2    Lomonossoff, G.P.3
  • 37
    • 16444369701 scopus 로고    scopus 로고
    • Production of Desmodus rotundus salivary plasminogen activator alpha1 (DSPAalpha1) in tobacco is hampered by proteolysis
    • DOI 10.1002/bit.20410
    • Schiermeyer A, Schinkel H, Apel S, Fischer R, Schillberg S (2005) Production of Desmodus rotundas salivary plasminogen activator alpha 1 (DSPA alpha 1) in tobacco is hampered by proteolysis. Biotechnol Bioeng 89: 848-858. (Pubitemid 40476484)
    • (2005) Biotechnology and Bioengineering , vol.89 , Issue.7 , pp. 848-858
    • Schiermeyer, A.1    Schinkel, H.2    Apel, S.3    Fischer, R.4    Schillberg, S.5
  • 38
    • 79960872123 scopus 로고    scopus 로고
    • A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children
    • Bélard S, Issifou S, Hounkpatin AB, Schaumburg F, Ngoa UA, et al. (2011) A randomized controlled phase Ib trial of the malaria vaccine candidate GMZ2 in African children. PloS One 6: e22525.
    • (2011) PloS One , vol.6
    • Bélard, S.1    Issifou, S.2    Hounkpatin, A.B.3    Schaumburg, F.4    Ngoa, U.A.5
  • 39
    • 77956481961 scopus 로고    scopus 로고
    • Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambaréné, Gabon
    • Mordmüller B, Szywon K, Greutelaers B, Esen M, Mewono L, et al. (2010) Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambaréné, Gabon. Vaccine 28: 6698-6703.
    • (2010) Vaccine , vol.28 , pp. 6698-6703
    • Mordmüller, B.1    Szywon, K.2    Greutelaers, B.3    Esen, M.4    Mewono, L.5
  • 40
    • 46249103583 scopus 로고    scopus 로고
    • A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits
    • Remarque EJ, Faber BW, Kocken CHM, Thomas AW (2008) A diversity-covering approach to immunization with Plasmodium falciparum apical membrane antigen 1 induces broader allelic recognition and growth inhibition responses in rabbits. Infect Immun 76: 2660-2670.
    • (2008) Infect Immun , vol.76 , pp. 2660-2670
    • Remarque, E.J.1    Faber, B.W.2    Kocken, C.H.M.3    Thomas, A.W.4
  • 41
    • 84863304598 scopus 로고    scopus 로고
    • R Core Team. R Foundation for Statistical Computing. Available
    • R Core Team (2012). R: A language and environment for statistical computing. R Foundation for Statistical Computing. Available: http://www.R-project.org.
    • (2012) R: A Language and Environment for Statistical Computing
  • 42
    • 0019837431 scopus 로고
    • Complete in vitro maturation of Plasmodium falciparum gametocytes
    • Ifediba T, Vanderberg JP (1981) Complete in vitro maturation of Plasmodium falciparum gametocytes. Nature 29: 364-366. (Pubitemid 12202857)
    • (1981) Nature , vol.294 , Issue.5839 , pp. 364-366
    • Ifediba, T.1    Vanderberg, J.P.2
  • 44
    • 84872585440 scopus 로고    scopus 로고
    • Malaria parasites co-opt human factor H to prevent complement-mediated lysis in the mosquito midgut
    • In press
    • Simon N, Lasonder E, Scheuermayer M, Kuehn A, Tews S, et al. (2013) Malaria parasites co-opt human factor H to prevent complement-mediated lysis in the mosquito midgut. Cell Host Microbe: In press.
    • (2013) Cell Host Microbe
    • Simon, N.1    Lasonder, E.2    Scheuermayer, M.3    Kuehn, A.4    Tews, S.5
  • 45
    • 0013649045 scopus 로고
    • Experiments upon the feeding of Aedes aegypti through animal membranes with a view to applying the method to the chemotherapy of malaria
    • Bishop A, Gilchrist BM (1946) Experiments upon the feeding of Aedes aegypti through animal membranes with a view to applying the method to the chemotherapy of malaria. Parasitology 37: 85-100.
    • (1946) Parasitology , vol.37 , pp. 85-100
    • Bishop, A.1    Gilchrist, B.M.2
  • 47
    • 0028472203 scopus 로고
    • Effects of para-aminobenzoic acid, insulin, and gentamicin on Plasmodium falciparum development in anopheline mosquitoes (Diptera: Culicidae)
    • Beier MS, Pumpuni CB, Beier JC, Davis JR (1994) Effects of para-aminobenzoic acid, insulin, and gentamicin on Plasmodium falciparum development in anopheline mosquitoes (Diptera: Culicidae). J Med Entomol 31: 561-565.
    • (1994) J Med Entomol , vol.31 , pp. 561-565
    • Beier, M.S.1    Pumpuni, C.B.2    Beier, J.C.3    Davis, J.R.4
  • 48
    • 0012134349 scopus 로고    scopus 로고
    • Available: Accessed 2013 October 31
    • Joosse SA (2011) Fisher's exact test. Available: http://in-silico.net/ tools/statistics/fisher-exact-test. Accessed 2013 October 31.
    • (2011) Fisher's Exact Test
    • Joosse, S.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.