BDC12-4.1 T-cell receptor transgenic insulin-specific CD4 T cells are resistant to in vitro differentiation into functional Foxp3+ T regulatory cells

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Sarikonda, Ghanashyam ^a   Fousteri, Georgia ^a,c   Sachithanantham, Sowbarnika ^a   Miller, Jacqueline F ^a   Dave, Amy ^a   Juntti, Therese ^a   Coppieters, Ken T ^b   Von Herrath, Matthias ^a,b  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b NOVO NORDISK INC   (United States)

^c SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD69 ANTIGEN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; AUTOANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; INSULIN; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNOREACTIVITY; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN SYNTHESIS; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PHENOTYPE; PLASTICITY; POLARIZATION; PROTEIN BINDING; REGULATORY T LYMPHOCYTE; SPLEEN CELL; TH1 CELL; TH17 CELL; TH2 CELL; THYMOCYTE; ADOPTIVE TRANSFER; ANIMAL; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 1; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; NONOBESE DIABETIC MOUSE; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; AUTOANTIGENS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 1; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; INSULIN; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES, REGULATORY;

EID: 84911479095     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112242     Document Type: Article

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