Oxidative DNA damage in the in utero initiation of postnatal neurodevelopmental deficits by normal fetal and ethanol-enhanced oxidative stress in oxoguanine glycosylase 1 knockout mice

Free Radical Biology and Medicine

Volumn 78, Issue , 2015, Pages 23-29

  Miller Pinsler, Lutfiya ^a   Pinto, Daniel J ^a   Wells, Peter G ^a,b  

^a Harvard Universny   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Behavioraldeficits; DNA oxidation; Ethanol; Freeradicals; Neurodevelopmentaldeficits; OGG1 mice; Passiveavoidance; Phenylbutylnitrone; Reactiveoxygenspecies

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALCOHOL; OXOGUANINE GLYCOSYLASE 1; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG; 8-OXO-7-HYDRODEOXYGUANOSINE; AMINE OXIDE; CENTRAL DEPRESSANT AGENT; DEOXYGUANOSINE; DNA GLYCOSYLTRANSFERASE; OGG1 PROTEIN, MOUSE; PHENYL-N-TERT-BUTYLNITRONE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ARTICLE; DNA DAMAGE; DNA REPAIR; FETUS; FETUS WEIGHT; GENOTYPE; KNOCKOUT MOUSE; LATENT PERIOD; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PASSIVE AVOIDANCE TEST; PHENOTYPE; POSTNATAL DEVELOPMENT; PROGENY; SIGNAL TRANSDUCTION; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL EMBRYO; AVOIDANCE BEHAVIOR; BRAIN; C57BL MOUSE; CHEMICALLY INDUCED; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECTS; DRUG THERAPY; FEMALE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; PREGNANCY; PRENATAL EXPOSURE;

MUS;

ANIMALS; AVOIDANCE LEARNING; BRAIN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CYCLIC N-OXIDES; DEOXYGUANOSINE; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; EMBRYO, MAMMALIAN; ETHANOL; FEMALE; FETUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENOTYPE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; REACTIVE OXYGEN SPECIES;

EID: 84911469202     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.09.026     Document Type: Article

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