Oxidative DNA damage and repair in teratogenesis and neurodevelopmental deficits

Birth Defects Research Part C - Embryo Today: Reviews

Volumn 90, Issue 2, 2010, Pages 103-109

  Wells, Peter G ^a   McCallum, Gordon P ^a   Lam, Kyla C H ^a   Henderson, Jeffrey T ^a   Ondovcik, Stephanie L ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; BENZO[A]PYRENE; CLADRIBINE; CYCLOPHOSPHAMIDE; CYTOCHROME P450; HYDROGEN PEROXIDE; HYDROXYL RADICAL; METHAMPHETAMINE; PHENYTOIN; PROSTAGLANDIN SYNTHASE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TERATOGENIC AGENT; THALIDOMIDE; XENOBIOTIC AGENT;

APOPTOSIS; ATAXIA TELANGIECTASIA; BIRTH DEFECT; CARCINOGENESIS; CHEMICAL MODIFICATION; COCKAYNE SYNDROME; COVALENT BOND; DEVELOPMENTAL DISORDER; DEVELOPMENTAL STAGE; DNA DAMAGE; DNA REPAIR; DOSE RESPONSE; DOUBLE STRANDED DNA BREAK; ELECTROENCEPHALOGRAM; ELECTROPHILICITY; EMBRYO; EMBRYO CULTURE; EMBRYO DEVELOPMENT; EMBRYOPATHY; ENZYME ACTIVATION; EXPOSURE; FETUS DEVELOPMENT; GENE MUTATION; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; IONIZING RADIATION; MACROMOLECULE; MITOCHONDRIAL ENERGY TRANSFER; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PREVALENCE; PRIORITY JOURNAL; RADIATION EXPOSURE; REVIEW; SIGNAL TRANSDUCTION; TERATOGENESIS;

ANIMALS; BENZO(A)PYRENE; DNA; DNA DAMAGE; DNA REPAIR; EMBRYO, MAMMALIAN; FEMALE; FETAL DISEASES; GUANINE; MALE; METABOLIC DETOXICATION, DRUG; MICE; MICE, KNOCKOUT; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHENYTOIN; PROTEINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TERATOGENS; THALIDOMIDE; TUMOR SUPPRESSOR PROTEIN P53; XENOBIOTICS;

ATAXIA TELANGIECTASIA;

EID: 77953503607     PISSN: 1542975X     EISSN: 15429768     Source Type: Journal    
DOI: 10.1002/bdrc.20177     Document Type: Review

References (20)

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2. Bhuller Y, Wells PG. 2006. A developmental role for ataxia-telangiectasia mutated in protecting the embryo from spontaneous and phenytoinenhanced embryopathies in culture. Toxicol Sci 93:156-163.
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