4(1H)-pyridone and 4(1H)-quinolone derivatives as antimalarials with erythrocytic, exoerythrocytic, and transmission blocking activities

Current Topics in Medicinal Chemistry

Volumn 14, Issue 14, 2014, Pages 1693-1705

  Monastyrskyi, Andrii ^a   Kyle, Dennis E ^b   Manetsch, Roman ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

1,2,3,4 tetrahydroacdridone; 4(1H) quinolone; Antimalarial activity; Phenoxyethoxy 4(1H) quinolone; Structure property relationship; Structureactivity relationship

Indexed keywords

1,2,3,4 TETRAHYDROACRIDONE; 2 ARYL 3 ESTER 4(1H) QUINOLONES; 3 ARYL 4(1H) QUINOLONE; 3 ESTER 4 (1H) QUINOLONE; 4 (1H) PYRIDONE; 4(1H) QUINOLONE DERIVATIVE; ANTIMALARIAL AGENT; ATOVAQUONE; CHLOROQUINE; CLOPIDOL; DIHYDROACRIDINEDIONE; FLOXACRINE; HYDROXY 2 DODECYL 4(1H) QUINOLONE; PHENOXYETHOXY 4(1H) QUINOLONE; PHENOXYETHOXY ESTER QUINOLONES; PRIMAQUINE; TETRAHYDROACRIDONE; UNCLASSIFIED DRUG; PYRIDONE DERIVATIVE; QUINOLONE DERIVATIVE;

ANTIMALARIAL ACTIVITY; ARTICLE; DISEASE ERADICATION; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG EFFICACY; EC50; ERYTHROCYTIC ACTIVITY; EXOERYTHROCYTIC ACTIVITY; IC50; LIFE CYCLE; MALARIA CONTROL; MORTALITY; NONHUMAN; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION; TRANSMISSION BLOCKING ACTIVITY; ANIMAL; CHEMISTRY; DRUG EFFECTS; ERYTHROCYTE; MALARIA; PRECLINICAL STUDY; TRANSMISSION;

ANIMALS; ANTIMALARIALS; DRUG EVALUATION, PRECLINICAL; ERYTHROCYTES; MALARIA; PYRIDONES; QUINOLONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84911421525     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026614666140808124638     Document Type: Article

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