-
1
-
-
76049092146
-
Acyl-CoA synthesis, lipid metabolism and lipotoxicity
-
Li, L. O., Klett, E. L., and Coleman, R. A. (2010) Acyl-CoA synthesis, lipid metabolism and lipotoxicity. Biochim. Biophys. Acta 1801, 246-251
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 246-251
-
-
Li, L.O.1
Klett, E.L.2
Coleman, R.A.3
-
2
-
-
77953868236
-
Lipid-induced insulin resistance: Unravelling the mechanism
-
Samuel, V. T., Petersen, K. F., and Shulman, G. I. (2010) Lipid-induced insulin resistance: unravelling the mechanism. Lancet 375, 2267-2277
-
(2010)
Lancet
, vol.375
, pp. 2267-2277
-
-
Samuel, V.T.1
Petersen, K.F.2
Shulman, G.I.3
-
3
-
-
76049091112
-
Lipid homeostasis, lipotoxicity and the metabolic syndrome
-
Unger, R. H., Clark, G. O., Scherer, P. E., and Orci, L. (2010) Lipid homeostasis, lipotoxicity and the metabolic syndrome. Biochim. Biophys. Acta 1801, 209-214
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 209-214
-
-
Unger, R.H.1
Clark, G.O.2
Scherer, P.E.3
Orci, L.4
-
4
-
-
77953356804
-
Gluttony, sloth and the metabolic syndrome: A roadmap to lipotoxicity
-
Unger, R. H., and Scherer, P. E. (2010) Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity. Trends Endocrinol. Metab. 21, 345-352
-
(2010)
Trends Endocrinol. Metab.
, vol.21
, pp. 345-352
-
-
Unger, R.H.1
Scherer, P.E.2
-
5
-
-
80053408094
-
Fatty acids, obesity, and insulin resistance: Time for a reevaluation
-
Karpe, F., Dickmann, J. R., and Frayn, K. N. (2011) Fatty acids, obesity, and insulin resistance: time for a reevaluation. Diabetes 60, 2441-2449
-
(2011)
Diabetes
, vol.60
, pp. 2441-2449
-
-
Karpe, F.1
Dickmann, J.R.2
Frayn, K.N.3
-
6
-
-
70349496577
-
Relationship between body fat mass and free fatty acid kinetics in men and women
-
Mittendorfer, B., Magkos, F., Fabbrini, E., Mohammed, B. S., and Klein, S. (2009) Relationship between body fat mass and free fatty acid kinetics in men and women. Obesity 17, 1872-1877
-
(2009)
Obesity
, vol.17
, pp. 1872-1877
-
-
Mittendorfer, B.1
Magkos, F.2
Fabbrini, E.3
Mohammed, B.S.4
Klein, S.5
-
7
-
-
8844226709
-
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase
-
Zimmermann, R., Strauss, J. G., Haemmerle, G., Schoiswohl, G., Birner-Gruenberger, R., Riederer, M., Lass, A., Neuberger, G., Eisenhaber, F., Hermetter, A., and Zechner, R. (2004) Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. Science 306, 1383-1386
-
(2004)
Science
, vol.306
, pp. 1383-1386
-
-
Zimmermann, R.1
Strauss, J.G.2
Haemmerle, G.3
Schoiswohl, G.4
Birner-Gruenberger, R.5
Riederer, M.6
Lass, A.7
Neuberger, G.8
Eisenhaber, F.9
Hermetter, A.10
Zechner, R.11
-
8
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
Haemmerle, G., Lass, A., Zimmermann, R., Gorkiewicz, G., Meyer, C., Rozman, J., Heldmaier, G., Maier, R., Theussl, C., Eder, S., Kratky, D., Wagner, E. F., Klingenspor, M., Hoefler, G., and Zechner, R. (2006) Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312, 734-737
-
(2006)
Science
, vol.312
, pp. 734-737
-
-
Haemmerle, G.1
Lass, A.2
Zimmermann, R.3
Gorkiewicz, G.4
Meyer, C.5
Rozman, J.6
Heldmaier, G.7
Maier, R.8
Theussl, C.9
Eder, S.10
Kratky, D.11
Wagner, E.F.12
Klingenspor, M.13
Hoefler, G.14
Zechner, R.15
-
9
-
-
68049092870
-
Neutral lipid storage disease: Genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5
-
Schweiger, M., Lass, A., Zimmermann, R., Eichmann, T. O., and Zechner, R. (2009) Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5. Am. J. Physiol. Endocrinol. Metab. 297, E289-E296
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
, pp. E289-E296
-
-
Schweiger, M.1
Lass, A.2
Zimmermann, R.3
Eichmann, T.O.4
Zechner, R.5
-
10
-
-
84887995002
-
Development of small-molecule inhibitors targeting adipose triglyceride lipase
-
Mayer, N., Schweiger, M., Romauch, M., Grabner, G. F., Eichmann, T. O., Fuchs, E., Ivkovic, J., Heier, C., Mrak, I., Lass, A., Höfler, G., Fledelius, C., Zechner, R., Zimmermann, R., and Breinbauer, R. (2013) Development of small-molecule inhibitors targeting adipose triglyceride lipase. Nat. Chem. Biol. 9, 785-787
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 785-787
-
-
Mayer, N.1
Schweiger, M.2
Romauch, M.3
Grabner, G.F.4
Eichmann, T.O.5
Fuchs, E.6
Ivkovic, J.7
Heier, C.8
Mrak, I.9
Lass, A.10
Höfler, G.11
Fledelius, C.12
Zechner, R.13
Zimmermann, R.14
Breinbauer, R.15
-
11
-
-
79960091939
-
Adipose triglyceride lipase contributes to cancer-associated cachexia
-
Das, S. K., Eder, S., Schauer, S., Diwoky, C., Temmel, H., Guertl, B., Gorkiewicz, G., Tamilarasan, K. P., Kumari, P., Trauner, M., Zimmermann, R., Vesely, P., Haemmerle, G., Zechner, R., and Hoefler, G. (2011) Adipose triglyceride lipase contributes to cancer-associated cachexia. Science 333, 233-238
-
(2011)
Science
, vol.333
, pp. 233-238
-
-
Das, S.K.1
Eder, S.2
Schauer, S.3
Diwoky, C.4
Temmel, H.5
Guertl, B.6
Gorkiewicz, G.7
Tamilarasan, K.P.8
Kumari, P.9
Trauner, M.10
Zimmermann, R.11
Vesely, P.12
Haemmerle, G.13
Zechner, R.14
Hoefler, G.15
-
12
-
-
78650107057
-
Lipolysis - A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores
-
Lass, A., Zimmermann, R., Oberer, M., and Zechner, R. (2011) Lipolysis-a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores. Prog. Lipid Res. 50, 14-27
-
(2011)
Prog. Lipid Res.
, vol.50
, pp. 14-27
-
-
Lass, A.1
Zimmermann, R.2
Oberer, M.3
Zechner, R.4
-
13
-
-
84896861094
-
Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A
-
Nagy, H. M., Paar, M., Heier, C., Moustafa, T., Hofer, P., Haemmerle, G., Lass, A., Zechner, R., Oberer, M., and Zimmermann, R. (2014) Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A. Biochim. Biophys. Acta 1841, 588-594
-
(2014)
Biochim. Biophys. Acta
, vol.1841
, pp. 588-594
-
-
Nagy, H.M.1
Paar, M.2
Heier, C.3
Moustafa, T.4
Hofer, P.5
Haemmerle, G.6
Lass, A.7
Zechner, R.8
Oberer, M.9
Zimmermann, R.10
-
14
-
-
33646128723
-
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome
-
Lass, A., Zimmermann, R., Haemmerle, G., Riederer, M., Schoiswohl, G., Schweiger, M., Kienesberger, P., Strauss, J. G., Gorkiewicz, G., and Zechner, R. (2006) Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. Cell Metab. 3, 309-319
-
(2006)
Cell Metab.
, vol.3
, pp. 309-319
-
-
Lass, A.1
Zimmermann, R.2
Haemmerle, G.3
Riederer, M.4
Schoiswohl, G.5
Schweiger, M.6
Kienesberger, P.7
Strauss, J.G.8
Gorkiewicz, G.9
Zechner, R.10
-
15
-
-
80054778472
-
The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively
-
Cornaciu, I., Boeszoermenyi, A., Lindermuth, H., Nagy, H. M., Cerk, I. K., Ebner, C., Salzburger, B., Gruber, A., Schweiger, M., Zechner, R., Lass, A., Zimmermann, R., and Oberer, M. (2011) The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively. PLoS One 6, e26349
-
(2011)
PLoS One
, vol.6
, pp. e26349
-
-
Cornaciu, I.1
Boeszoermenyi, A.2
Lindermuth, H.3
Nagy, H.M.4
Cerk, I.K.5
Ebner, C.6
Salzburger, B.7
Gruber, A.8
Schweiger, M.9
Zechner, R.10
Lass, A.11
Zimmermann, R.12
Oberer, M.13
-
16
-
-
84893134937
-
1 switch gene 2 (G0S2)
-
1 switch gene 2 (G0S2). J. Biol. Chem. 289, 1905-1916
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 1905-1916
-
-
Heckmann, B.L.1
Zhang, X.2
Xie, X.3
Saarinen, A.4
Lu, X.5
Yang, X.6
Liu, J.7
-
17
-
-
77956865739
-
Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2
-
Lu, X., Yang, X., and Liu, J. (2010) Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2. Cell Cycle 9, 2719-2725
-
(2010)
Cell Cycle
, vol.9
, pp. 2719-2725
-
-
Lu, X.1
Yang, X.2
Liu, J.3
-
18
-
-
84867364913
-
G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase
-
Schweiger, M., Paar, M., Eder, C., Brandis, J., Moser, E., Gorkiewicz, G., Grond, S., Radner, F. P., Cerk, I., Cornaciu, I., Oberer, M., Kersten, S., Zechner, R., Zimmermann, R., and Lass, A. (2012) G0/G1 switch gene-2 regulates human adipocyte lipolysis by affecting activity and localization of adipose triglyceride lipase. J. Lipid Res. 53, 2307-2317
-
(2012)
J. Lipid Res.
, vol.53
, pp. 2307-2317
-
-
Schweiger, M.1
Paar, M.2
Eder, C.3
Brandis, J.4
Moser, E.5
Gorkiewicz, G.6
Grond, S.7
Radner, F.P.8
Cerk, I.9
Cornaciu, I.10
Oberer, M.11
Kersten, S.12
Zechner, R.13
Zimmermann, R.14
Lass, A.15
-
19
-
-
84881484385
-
The G0/G1 switch gene 2 is an important regulator of hepatic triglyceride metabolism
-
Wang, Y., Zhang, Y., Qian, H., Lu, J., Zhang, Z., Min, X., Lang, M., Yang, H., Wang, N., and Zhang, P. (2013) The G0/G1 switch gene 2 is an important regulator of hepatic triglyceride metabolism. PLoS One 8, e72315
-
(2013)
PLoS One
, vol.8
, pp. e72315
-
-
Wang, Y.1
Zhang, Y.2
Qian, H.3
Lu, J.4
Zhang, Z.5
Min, X.6
Lang, M.7
Yang, H.8
Wang, N.9
Zhang, P.10
-
20
-
-
77249118270
-
1 switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase
-
1 switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase. Cell Metab. 11, 194-205
-
(2010)
Cell Metab.
, vol.11
, pp. 194-205
-
-
Yang, X.1
Lu, X.2
Lombès, M.3
Rha, G.B.4
Chi, Y.I.5
Guerin, T.M.6
Smart, E.J.7
Liu, J.8
-
21
-
-
81755171447
-
Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes
-
Yang, X., Zhang, X., Heckmann, B. L., Lu, X., and Liu, J. (2011) Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes. J. Biol. Chem. 286, 40477-40485
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 40477-40485
-
-
Yang, X.1
Zhang, X.2
Heckmann, B.L.3
Lu, X.4
Liu, J.5
-
22
-
-
0031760438
-
Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2)
-
Bächner, D., Ahrens, M., Schröder, D., Hoffmann, A., Lauber, J., Betat, N., Steinert, P., Flohé, L., and Gross, G. (1998) Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev. Dyn. 213, 398-411
-
(1998)
Dev. Dyn.
, vol.213
, pp. 398-411
-
-
Bächner, D.1
Ahrens, M.2
Schröder, D.3
Hoffmann, A.4
Lauber, J.5
Betat, N.6
Steinert, P.7
Flohé, L.8
Gross, G.9
-
23
-
-
29144451332
-
The G0/G1 switch gene 2 is a novel PPAR target gene
-
Zandbergen, F., Mandard, S., Escher, P., Tan, N. S., Patsouris, D., Jatkoe, T., Rojas-Caro, S., Madore, S., Wahli, W., Tafuri, S., Müller, M., and Kersten, S. (2005) The G0/G1 switch gene 2 is a novel PPAR target gene. Biochem. J. 392, 313-324
-
(2005)
Biochem. J.
, vol.392
, pp. 313-324
-
-
Zandbergen, F.1
Mandard, S.2
Escher, P.3
Tan, N.S.4
Patsouris, D.5
Jatkoe, T.6
Rojas-Caro, S.7
Madore, S.8
Wahli, W.9
Tafuri, S.10
Müller, M.11
Kersten, S.12
-
24
-
-
84902256587
-
G0/G1 switch gene 2 has a critical role in adipocyte differentiation
-
Choi, H., Lee, H., Kim, T. H., Kim, H. J., Lee, Y. J., Lee, S. J., Yu, J. H., Kim, D., Kim, K. S., Park, S. W., and Kim, J. W. (2014) G0/G1 switch gene 2 has a critical role in adipocyte differentiation. Cell Death Differ. 21, 1071-1080
-
(2014)
Cell Death Differ.
, vol.21
, pp. 1071-1080
-
-
Choi, H.1
Lee, H.2
Kim, T.H.3
Kim, H.J.4
Lee, Y.J.5
Lee, S.J.6
Yu, J.H.7
Kim, D.8
Kim, K.S.9
Park, S.W.10
Kim, J.W.11
-
25
-
-
84899884588
-
Mice lacking G0S2 are lean and cold-tolerant
-
Ma, T., Lopez-Aguiar, A. G., Li, A., Lu, Y., Sekula, D., Nattie, E. E., Freemantle, S., and Dmitrovsky, E. (2014) Mice lacking G0S2 are lean and cold-tolerant. Cancer Biol. Ther. 15, 643-650
-
(2014)
Cancer Biol. Ther.
, vol.15
, pp. 643-650
-
-
Ma, T.1
Lopez-Aguiar, A.G.2
Li, A.3
Lu, Y.4
Sekula, D.5
Nattie, E.E.6
Freemantle, S.7
Dmitrovsky, E.8
-
26
-
-
84894484467
-
Targeted disruption of G0/G1 switch gene 2 enhances adipose lipolysis, alters hepatic energy balance, and alleviates high-fat diet-induced liver steatosis
-
Zhang, X., Xie, X., Heckmann, B. L., Saarinen, A. M., Czyzyk, T. A., and Liu, J. (2014) Targeted disruption of G0/G1 switch gene 2 enhances adipose lipolysis, alters hepatic energy balance, and alleviates high-fat diet-induced liver steatosis. Diabetes 63, 934-946
-
(2014)
Diabetes
, vol.63
, pp. 934-946
-
-
Zhang, X.1
Xie, X.2
Heckmann, B.L.3
Saarinen, A.M.4
Czyzyk, T.A.5
Liu, J.6
-
27
-
-
84894472160
-
Adipose triglyceride lipase and G0/G1 switch gene 2: Approaching proof of concept
-
Nielsen, T. S., and Møller, N. (2014) Adipose triglyceride lipase and G0/G1 switch gene 2: approaching proof of concept. Diabetes 63, 847-849
-
(2014)
Diabetes
, vol.63
, pp. 847-849
-
-
Nielsen, T.S.1
Møller, N.2
-
28
-
-
33749407193
-
ChREBP∗Mlx is the principal mediator of glucose-induced gene expression in the liver
-
Ma, L., Robinson, L. N., and Towle, H. C. (2006) ChREBP∗Mlx is the principal mediator of glucose-induced gene expression in the liver. J. Biol. Chem. 281, 28721-28730
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 28721-28730
-
-
Ma, L.1
Robinson, L.N.2
Towle, H.C.3
-
29
-
-
34249660144
-
TXNIP regulates peripheral glucose metabolism in humans
-
Parikh, H., Carlsson, E., Chutkow, W. A., Johansson, L. E., Storgaard, H., Poulsen, P., Saxena, R., Ladd, C., Schulze, P. C., Mazzini, M. J., Jensen, C. B., Krook, A., Björnholm, M., Tornqvist, H., Zierath, J. R., Ridderstra˚le, M., Altshuler, D., Lee, R. T., Vaag, A., Groop, L. C., and Mootha, V. K. (2007) TXNIP regulates peripheral glucose metabolism in humans. PLoS Med. 4, e158
-
(2007)
PLoS Med.
, vol.4
, pp. e158
-
-
Parikh, H.1
Carlsson, E.2
Chutkow, W.A.3
Johansson, L.E.4
Storgaard, H.5
Poulsen, P.6
Saxena, R.7
Ladd, C.8
Schulze, P.C.9
Mazzini, M.J.10
Jensen, C.B.11
Krook, A.12
Björnholm, M.13
Tornqvist, H.14
Zierath, J.R.15
Ridderstra˚le, M.16
Altshuler, D.17
Lee, R.T.18
Vaag, A.19
Groop, L.C.20
Mootha, V.K.21
more..
-
30
-
-
84863574094
-
Reduced mRNA and protein expression of perilipin A and G0/G1 switch gene 2 (G0S2) in human adipose tissue in poorly controlled type 2 diabetes
-
Nielsen, T. S., Kampmann, U., Nielsen, R. R., Jessen, N., Orskov, L., Pedersen, S. B., Jørgensen, J. O., Lund, S., and Møller, N. (2012) Reduced mRNA and protein expression of perilipin A and G0/G1 switch gene 2 (G0S2) in human adipose tissue in poorly controlled type 2 diabetes. J. Clin. Endocrinol. Metab. 97, E1348-E1352
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
, pp. E1348-E1352
-
-
Nielsen, T.S.1
Kampmann, U.2
Nielsen, R.R.3
Jessen, N.4
Orskov, L.5
Pedersen, S.B.6
Jørgensen, J.O.7
Lund, S.8
Møller, N.9
-
31
-
-
84861664376
-
The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells
-
Yamada, T., Park, C. S., Burns, A., Nakada, D., and Lacorazza, H. D. (2012) The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells. PLoS One 7, e38280
-
(2012)
PLoS One
, vol.7
, pp. e38280
-
-
Yamada, T.1
Park, C.S.2
Burns, A.3
Nakada, D.4
Lacorazza, H.D.5
-
32
-
-
84892515213
-
G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol
-
Yamada, T., Park, C. S., Shen, Y., Rabin, K. R., and Lacorazza, H. D. (2014) G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol. Leuk. Res. 38, 210-217
-
(2014)
Leuk. Res.
, vol.38
, pp. 210-217
-
-
Yamada, T.1
Park, C.S.2
Shen, Y.3
Rabin, K.R.4
Lacorazza, H.D.5
-
33
-
-
70149097778
-
Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2
-
Welch, C., Santra, M. K., El-Assaad, W., Zhu, X., Huber, W. E., Keys, R. A., Teodoro, J. G., and Green, M. R. (2009) Identification of a protein, G0S2, that lacks Bcl-2 homology domains and interacts with and antagonizes Bcl-2. Cancer Res. 69, 6782-6789
-
(2009)
Cancer Res.
, vol.69
, pp. 6782-6789
-
-
Welch, C.1
Santra, M.K.2
El-Assaad, W.3
Zhu, X.4
Huber, W.E.5
Keys, R.A.6
Teodoro, J.G.7
Green, M.R.8
-
34
-
-
0031419262
-
Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) in cultured human blood mononuclear cells
-
Cristillo, A. D., Heximer, S. P., Russell, L., and Forsdyke, D. R. (1997) Cyclosporin A inhibits early mRNA expression of G0/G1 switch gene 2 (G0S2) in cultured human blood mononuclear cells. DNA Cell Biol. 16, 1449-1458
-
(1997)
DNA Cell Biol.
, vol.16
, pp. 1449-1458
-
-
Cristillo, A.D.1
Heximer, S.P.2
Russell, L.3
Forsdyke, D.R.4
-
35
-
-
22544480310
-
Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules
-
Koczan, D., Guthke, R., Thiesen, H. J., Ibrahim, S. M., Kundt, G., Krentz, H., Gross, G., and Kunz, M. (2005) Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules. Eur. J. Dermatol. 15, 251-257
-
(2005)
Eur. J. Dermatol.
, vol.15
, pp. 251-257
-
-
Koczan, D.1
Guthke, R.2
Thiesen, H.J.3
Ibrahim, S.M.4
Kundt, G.5
Krentz, H.6
Gross, G.7
Kunz, M.8
-
36
-
-
33750912016
-
Isolation and expression profiling of genes upregulated in bone marrowderived mononuclear cells of rheumatoid arthritis patients
-
Nakamura, N., Shimaoka, Y., Tougan, T., Onda, H., Okuzaki, D., Zhao, H., Fujimori, A., Yabuta, N., Nagamori, I., Tanigawa, A., Sato, J., Oda, T., Hayashida, K., Suzuki, R., Yukioka, M., Nojima, H., and Ochi, T. (2006) Isolation and expression profiling of genes upregulated in bone marrowderived mononuclear cells of rheumatoid arthritis patients. DNA Res. 13, 169-183
-
(2006)
DNA Res.
, vol.13
, pp. 169-183
-
-
Nakamura, N.1
Shimaoka, Y.2
Tougan, T.3
Onda, H.4
Okuzaki, D.5
Zhao, H.6
Fujimori, A.7
Yabuta, N.8
Nagamori, I.9
Tanigawa, A.10
Sato, J.11
Oda, T.12
Hayashida, K.13
Suzuki, R.14
Yukioka, M.15
Nojima, H.16
Ochi, T.17
-
37
-
-
0026094018
-
A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated
-
Russell, L., and Forsdyke, D. R. (1991) A human putative lymphocyte G0/G1 switch gene containing a CpG-rich island encodes a small basic protein with the potential to be phosphorylated. DNA Cell Biol. 10, 581-591
-
(1991)
DNA Cell Biol.
, vol.10
, pp. 581-591
-
-
Russell, L.1
Forsdyke, D.R.2
-
38
-
-
84891933726
-
Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation
-
Kioka, H., Kato, H., Fujikawa, M., Tsukamoto, O., Suzuki, T., Imamura, H., Nakano, A., Higo, S., Yamazaki, S., Matsuzaki, T., Takafuji, K., Asanuma, H., Asakura, M., Minamino, T., Shintani, Y., Yoshida, M., Noji, H., Kitakaze, M., Komuro, I., Asano, Y., and Takashima, S. (2014) Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation. Proc. Natl. Acad. Sci. U.S.A. 111, 273-278
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 273-278
-
-
Kioka, H.1
Kato, H.2
Fujikawa, M.3
Tsukamoto, O.4
Suzuki, T.5
Imamura, H.6
Nakano, A.7
Higo, S.8
Yamazaki, S.9
Matsuzaki, T.10
Takafuji, K.11
Asanuma, H.12
Asakura, M.13
Minamino, T.14
Shintani, Y.15
Yoshida, M.16
Noji, H.17
Kitakaze, M.18
Komuro, I.19
Asano, Y.20
Takashima, S.21
more..
-
39
-
-
77949877527
-
Identification of G0S2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches
-
Kusakabe, M., Kutomi, T., Watanabe, K., Emoto, N., Aki, N., Kage, H., Hamano, E., Kitagawa, H., Nagase, T., Sano, A., Yoshida, Y., Fukami, T., Murakawa, T., Nakajima, J., Takamoto, S., Ota, S., Fukayama, M., Yatomi, Y., Ohishi, N., and Takai, D. (2010) Identification of G0S2 as a gene frequently methylated in squamous lung cancer by combination of in silico and experimental approaches. Int. J. Cancer 126, 1895-1902
-
(2010)
Int. J. Cancer
, vol.126
, pp. 1895-1902
-
-
Kusakabe, M.1
Kutomi, T.2
Watanabe, K.3
Emoto, N.4
Aki, N.5
Kage, H.6
Hamano, E.7
Kitagawa, H.8
Nagase, T.9
Sano, A.10
Yoshida, Y.11
Fukami, T.12
Murakawa, T.13
Nakajima, J.14
Takamoto, S.15
Ota, S.16
Fukayama, M.17
Yatomi, Y.18
Ohishi, N.19
Takai, D.20
more..
-
40
-
-
70450253169
-
Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists
-
Kusakabe, M., Watanabe, K., Emoto, N., Aki, N., Kage, H., Nagase, T., Nakajima, J., Yatomi, Y., Ohishi, N., and Takai, D. (2009) Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists. Biochem. Biophys. Res. Commun. 390, 1283-1287
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 1283-1287
-
-
Kusakabe, M.1
Watanabe, K.2
Emoto, N.3
Aki, N.4
Kage, H.5
Nagase, T.6
Nakajima, J.7
Yatomi, Y.8
Ohishi, N.9
Takai, D.10
-
41
-
-
4344628907
-
Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing
-
Tokumaru, Y., Yamashita, K., Osada, M., Nomoto, S., Sun, D. I., Xiao, Y., Hoque, M. O., Westra, W. H., Califano, J. A., and Sidransky, D. (2004) Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing. Cancer Res. 64, 5982-5987
-
(2004)
Cancer Res.
, vol.64
, pp. 5982-5987
-
-
Tokumaru, Y.1
Yamashita, K.2
Osada, M.3
Nomoto, S.4
Sun, D.I.5
Xiao, Y.6
Hoque, M.O.7
Westra, W.H.8
Califano, J.A.9
Sidransky, D.10
-
42
-
-
77951245602
-
The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase
-
Gruber, A., Cornaciu, I., Lass, A., Schweiger, M., Poeschl, M., Eder, C., Kumari, M., Schoiswohl, G., Wolinski, H., Kohlwein, S. D., Zechner, R., Zimmermann, R., and Oberer, M. (2010) The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase. J. Biol. Chem. 285, 12289-12298
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 12289-12298
-
-
Gruber, A.1
Cornaciu, I.2
Lass, A.3
Schweiger, M.4
Poeschl, M.5
Eder, C.6
Kumari, M.7
Schoiswohl, G.8
Wolinski, H.9
Kohlwein, S.D.10
Zechner, R.11
Zimmermann, R.12
Oberer, M.13
-
43
-
-
77954658402
-
Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomyces cerevisiae
-
Heier, C., Taschler, U., Rengachari, S., Oberer, M., Wolinski, H., Natter, K., Kohlwein, S. D., Leber, R., and Zimmermann, R. (2010) Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta 1801, 1063-1071
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 1063-1071
-
-
Heier, C.1
Taschler, U.2
Rengachari, S.3
Oberer, M.4
Wolinski, H.5
Natter, K.6
Kohlwein, S.D.7
Leber, R.8
Zimmermann, R.9
-
44
-
-
41949084516
-
Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase
-
Kienesberger, P. C., Lass, A., Preiss-Landl, K., Wolinski, H., Kohlwein, S. D., Zimmermann, R., and Zechner, R. (2008) Identification of an insulin-regulated lysophospholipase with homology to neuropathy target esterase. J. Biol. Chem. 283, 5908-5917
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5908-5917
-
-
Kienesberger, P.C.1
Lass, A.2
Preiss-Landl, K.3
Wolinski, H.4
Kohlwein, S.D.5
Zimmermann, R.6
Zechner, R.7
-
45
-
-
84894100520
-
Measurement of lipolysis
-
Schweiger, M., Eichmann, T. O., Taschler, U., Zimmermann, R., Zechner, R., and Lass, A. (2014) Measurement of lipolysis. Methods Enzymol. 538, 171-193
-
(2014)
Methods Enzymol.
, vol.538
, pp. 171-193
-
-
Schweiger, M.1
Eichmann, T.O.2
Taschler, U.3
Zimmermann, R.4
Zechner, R.5
Lass, A.6
-
46
-
-
79955958008
-
Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance
-
Taschler, U., Radner, F. P., Heier, C., Schreiber, R., Schweiger, M., Schoiswohl, G., Preiss-Landl, K., Jaeger, D., Reiter, B., Koefeler, H. C., Wojciechowski, J., Theussl, C., Penninger, J. M., Lass, A., Haemmerle, G., Zechner, R., and Zimmermann, R. (2011) Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J. Biol. Chem. 286, 17467-17477
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17467-17477
-
-
Taschler, U.1
Radner, F.P.2
Heier, C.3
Schreiber, R.4
Schweiger, M.5
Schoiswohl, G.6
Preiss-Landl, K.7
Jaeger, D.8
Reiter, B.9
Koefeler, H.C.10
Wojciechowski, J.11
Theussl, C.12
Penninger, J.M.13
Lass, A.14
Haemmerle, G.15
Zechner, R.16
Zimmermann, R.17
-
47
-
-
77049143386
-
The determination of enzyme inhibitor constants
-
Dixon, M. (1953) The determination of enzyme inhibitor constants. Biochem. J. 55, 170-171
-
(1953)
Biochem. J.
, vol.55
, pp. 170-171
-
-
Dixon, M.1
-
48
-
-
33846029180
-
Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism
-
Schweiger, M., Schreiber, R., Haemmerle, G., Lass, A., Fledelius, C., Jacobsen, P., Tornqvist, H., Zechner, R., and Zimmermann, R. (2006) Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism. J. Biol. Chem. 281, 40236-40241
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 40236-40241
-
-
Schweiger, M.1
Schreiber, R.2
Haemmerle, G.3
Lass, A.4
Fledelius, C.5
Jacobsen, P.6
Tornqvist, H.7
Zechner, R.8
Zimmermann, R.9
-
49
-
-
0346962962
-
Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase
-
Ebdrup, S., Sørensen, L. G., Olsen, O. H., and Jacobsen, P. (2004) Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase. J. Med. Chem. 47, 400-410
-
(2004)
J. Med. Chem.
, vol.47
, pp. 400-410
-
-
Ebdrup, S.1
Sørensen, L.G.2
Olsen, O.H.3
Jacobsen, P.4
-
50
-
-
66349121084
-
Mammalian patatin domain containing proteins: A family with diverse lipolytic activities involved in multiple biological functions
-
Kienesberger, P. C., Oberer, M., Lass, A., and Zechner, R. (2009) Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions. J. Lipid Res. 50, S63-S68
-
(2009)
J. Lipid Res.
, vol.50
, pp. S63-S68
-
-
Kienesberger, P.C.1
Oberer, M.2
Lass, A.3
Zechner, R.4
-
51
-
-
78650851786
-
Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation
-
Hoy, A. J., Bruce, C. R., Turpin, S. M., Morris, A. J., Febbraio, M. A., and Watt, M. J. (2011) Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation. Endocrinology 152, 48-58
-
(2011)
Endocrinology
, vol.152
, pp. 48-58
-
-
Hoy, A.J.1
Bruce, C.R.2
Turpin, S.M.3
Morris, A.J.4
Febbraio, M.A.5
Watt, M.J.6
-
52
-
-
71049114611
-
Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling
-
Kienesberger, P. C., Lee, D., Pulinilkunnil, T., Brenner, D. S., Cai, L., Magnes, C., Koefeler, H. C., Streith, I. E., Rechberger, G. N., Haemmerle, G., Flier, J. S., Zechner, R., Kim, Y. B., and Kershaw, E. E. (2009) Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling. J. Biol. Chem. 284, 30218-30229
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 30218-30229
-
-
Kienesberger, P.C.1
Lee, D.2
Pulinilkunnil, T.3
Brenner, D.S.4
Cai, L.5
Magnes, C.6
Koefeler, H.C.7
Streith, I.E.8
Rechberger, G.N.9
Haemmerle, G.10
Flier, J.S.11
Zechner, R.12
Kim, Y.B.13
Kershaw, E.E.14
-
53
-
-
0021247036
-
Inhibition of the hormone-sensitive lipase in adipose tissue by long-chain fatty acyl coenzyme A
-
Severson, D. L., and Hurley, B. (1984) Inhibition of the hormone-sensitive lipase in adipose tissue by long-chain fatty acyl coenzyme A. Lipids 19, 134-138
-
(1984)
Lipids
, vol.19
, pp. 134-138
-
-
Severson, D.L.1
Hurley, B.2
-
54
-
-
84860465005
-
Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase
-
Kumari, M., Schoiswohl, G., Chitraju, C., Paar, M., Cornaciu, I., Rangrez, A. Y., Wongsiriroj, N., Nagy, H. M., Ivanova, P. T., Scott, S. A., Knittelfelder, O., Rechberger, G. N., Birner-Gruenberger, R., Eder, S., Brown, H. A., Haemmerle, G., Oberer, M., Lass, A., Kershaw, E. E., Zimmermann, R., and Zechner, R. (2012) Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase. Cell Metab. 15, 691-702
-
(2012)
Cell Metab.
, vol.15
, pp. 691-702
-
-
Kumari, M.1
Schoiswohl, G.2
Chitraju, C.3
Paar, M.4
Cornaciu, I.5
Rangrez, A.Y.6
Wongsiriroj, N.7
Nagy, H.M.8
Ivanova, P.T.9
Scott, S.A.10
Knittelfelder, O.11
Rechberger, G.N.12
Birner-Gruenberger, R.13
Eder, S.14
Brown, H.A.15
Haemmerle, G.16
Oberer, M.17
Lass, A.18
Kershaw, E.E.19
Zimmermann, R.20
Zechner, R.21
more..
-
55
-
-
73249123539
-
A novel clinical entity: Triglyceride deposit cardiomyovasculopathy
-
Hirano, K. (2009) A novel clinical entity: triglyceride deposit cardiomyovasculopathy. J. Atheroscler. Thromb. 16, 702-705
-
(2009)
J. Atheroscler. Thromb.
, vol.16
, pp. 702-705
-
-
Hirano, K.1
-
56
-
-
84893118765
-
Combinatorial peptide libraries: Mining for cell-binding peptides
-
Gray, B. P., and Brown, K. C. (2014) Combinatorial peptide libraries: mining for cell-binding peptides. Chem. Rev. 114, 1020-1081
-
(2014)
Chem. Rev.
, vol.114
, pp. 1020-1081
-
-
Gray, B.P.1
Brown, K.C.2
-
57
-
-
77957017973
-
Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue
-
Hossen, M. N., Kajimoto, K., Akita, H., Hyodo, M., Ishitsuka, T., and Harashima, H. (2010) Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue. J. Control Release 147, 261-268
-
(2010)
J. Control Release
, vol.147
, pp. 261-268
-
-
Hossen, M.N.1
Kajimoto, K.2
Akita, H.3
Hyodo, M.4
Ishitsuka, T.5
Harashima, H.6
-
58
-
-
2942703809
-
Reversal of obesity by targeted ablation of adipose tissue
-
Kolonin, M. G., Saha, P. K., Chan, L., Pasqualini, R., and Arap, W. (2004) Reversal of obesity by targeted ablation of adipose tissue. Nat. Med. 10, 625-632
-
(2004)
Nat. Med.
, vol.10
, pp. 625-632
-
-
Kolonin, M.G.1
Saha, P.K.2
Chan, L.3
Pasqualini, R.4
Arap, W.5
-
59
-
-
47749132272
-
The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding
-
Schweiger, M., Schoiswohl, G., Lass, A., Radner, F. P., Haemmerle, G., Malli, R., Graier, W., Cornaciu, I., Oberer, M., Salvayre, R., Fischer, J., Zechner, R., and Zimmermann, R. (2008) The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding. J. Biol. Chem. 283, 17211-17220
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 17211-17220
-
-
Schweiger, M.1
Schoiswohl, G.2
Lass, A.3
Radner, F.P.4
Haemmerle, G.5
Malli, R.6
Graier, W.7
Cornaciu, I.8
Oberer, M.9
Salvayre, R.10
Fischer, J.11
Zechner, R.12
Zimmermann, R.13
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