Development of small-molecule inhibitors targeting adipose triglyceride lipase

Nature Chemical Biology

Volumn 9, Issue 12, 2013, Pages 785-787

  Mayer, Nicole ^a   Schweiger, Martina ^b   Romauch, Matthias ^b   Grabner, Gernot F ^b   Eichmann, Thomas O ^b   Fuchs, Elisabeth ^a   Ivkovic, Jakov ^a   Heier, Christoph ^b   Mrak, Irina ^b   Lass, Achim ^b   Höfler, Gerald ^c   Fledelius, Christian ^d   Zechner, Rudolf ^b   Zimmermann, Robert ^b   Breinbauer, Rolf ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b UNIVERSITY OF GRAZ   (Austria)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

^d NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TRIGLYCERIDE LIPASE; ATGLISTATIN; FAT DROPLET; FATTY ACID; FORSKOLIN; OLIVE OIL; SMALL MOLECULE TRANSPORT AGENT; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ADIPOCYTE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DYSLIPIDEMIA; ENZYME ACTIVITY; ENZYME IMMOBILIZATION; FATTY ACID METABOLISM; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LIPID STORAGE; LIPOLYSIS; METABOLIC DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; TRIACYLGLYCEROL LIPASE BLOOD LEVEL;

ADIPOSE TISSUE, WHITE; ANIMALS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INHIBITORY CONCENTRATION 50; LIPASE; MICE; MICE, KNOCKOUT; MOLECULAR STRUCTURE; PHENYLUREA COMPOUNDS;

EID: 84887995002     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1359     Document Type: Article

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