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Volumn 91, Issue 4, 2014, Pages

Progressive obesity alters ovarian folliculogenesis with impacts on pro-inflammatory and steroidogenic signaling in female mice

Author keywords

Inflammation; Obesity; Ovary; Steroidogenesis

Indexed keywords

3BETA HYDROXY DELTA5 STEROID DEHYDROGENASE; AROMATASE; CD3 ANTIGEN; CD4 ANTIGEN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERMEDIN; MACROPHAGE DERIVED CHEMOKINE; MESSENGER RNA; RANTES; STEROIDOGENIC ACUTE REGULATORY PROTEIN; CYTOKINE; GLUCOSE BLOOD LEVEL; STEROID;

EID: 84911406795     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.114.121343     Document Type: Article
Times cited : (64)

References (91)
  • 1
    • 70849106162 scopus 로고    scopus 로고
    • The mammalian ovary from genesis to revelation
    • Edson MA, Nagaraja AK, Matzuk MM. The mammalian ovary from genesis to revelation. Endocr Rev 2009; 30:624-712.
    • (2009) Endocr Rev , vol.30 , pp. 624-712
    • Edson, M.A.1    Nagaraja, A.K.2    Matzuk, M.M.3
  • 2
    • 0022578632 scopus 로고
    • Hormonal regulation of P450scc (20,22-desmolase) and P450c17 (17 alpha-hydroxylase/17, 20-lyase) in cultured human granulosa cells
    • Voutilainen R, Tapanainen J, Chung BC, Matteson KJ, Miller WL. Hormonal regulation of P450scc (20,22-desmolase) and P450c17 (17 alpha-hydroxylase/17, 20-lyase) in cultured human granulosa cells. J Clin Endocrinol Metab 1986; 63:202-207.
    • (1986) J Clin Endocrinol Metab , vol.63 , pp. 202-207
    • Voutilainen, R.1    Tapanainen, J.2    Chung, B.C.3    Matteson, K.J.4    Miller, W.L.5
  • 3
    • 33744933179 scopus 로고    scopus 로고
    • Ovarian steroids: the good, the bad, and the signals that raise them
    • Jamnongjit M, Hammes SR. Ovarian steroids: the good, the bad, and the signals that raise them. Cell Cycle 2006; 5:1178-1183.
    • (2006) Cell Cycle , vol.5 , pp. 1178-1183
    • Jamnongjit, M.1    Hammes, S.R.2
  • 4
    • 0025759101 scopus 로고
    • Regulation of luteinizing hormone receptor messenger ribonucleic acid levels by gonadotropins, growth factors, and gonadotropin-releasing hormone in cultured rat granulosa cells
    • Piquette GN, LaPolt PS, Oikawa M, Hsueh AJ. Regulation of luteinizing hormone receptor messenger ribonucleic acid levels by gonadotropins, growth factors, and gonadotropin-releasing hormone in cultured rat granulosa cells. Endocrinol 1991; 128:2449-2456.
    • (1991) Endocrinol , vol.128 , pp. 2449-2456
    • Piquette, G.N.1    LaPolt, P.S.2    Oikawa, M.3    Hsueh, A.J.4
  • 5
    • 0023117109 scopus 로고
    • Steroidogenesis in the human fetal adrenal: a role for cholesterol synthesized de novo
    • Mason JI, Rainey WE. Steroidogenesis in the human fetal adrenal: a role for cholesterol synthesized de novo. J Clin Endocrinol Metab 1987; 64: 140-147.
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 140-147
    • Mason, J.I.1    Rainey, W.E.2
  • 6
    • 33847235315 scopus 로고    scopus 로고
    • StAR search-what we know about how the steroidogenic acute regulatory protein mediates mitochondrial cholesterol import
    • Miller WL. StAR search-what we know about how the steroidogenic acute regulatory protein mediates mitochondrial cholesterol import. Mol Endocrinol 2007; 21:589-601.
    • (2007) Mol Endocrinol , vol.21 , pp. 589-601
    • Miller, W.L.1
  • 7
    • 0022770127 scopus 로고
    • Cytochromes P-450 and the regulation of steroid synthesis
    • Hall PF. Cytochromes P-450 and the regulation of steroid synthesis. Steroids 1986; 48:131-196.
    • (1986) Steroids , vol.48 , pp. 131-196
    • Hall, P.F.1
  • 8
    • 0018449722 scopus 로고
    • Cholesterol side-chain cleavage, cytochrome P450, and the control of steroidogenesis
    • Simpson ER. Cholesterol side-chain cleavage, cytochrome P450, and the control of steroidogenesis. Mol Cell Endocrinol 1979; 13:213-227.
    • (1979) Mol Cell Endocrinol , vol.13 , pp. 213-227
    • Simpson, E.R.1
  • 9
    • 18844381164 scopus 로고    scopus 로고
    • Minireview: cellular redox state regulates hydroxysteroid dehydrogenase activity and intracellular hormone potency
    • Agarwal AK, Auchus RJ. Minireview: cellular redox state regulates hydroxysteroid dehydrogenase activity and intracellular hormone potency. Endocrinol 2005; 146:2531-2538.
    • (2005) Endocrinol , vol.146 , pp. 2531-2538
    • Agarwal, A.K.1    Auchus, R.J.2
  • 10
    • 0033304948 scopus 로고    scopus 로고
    • Medroxyprogesterone acetate and dexamethasone are competitive inhibitors of different human steroidogenic enzymes
    • Lee TC, Miller WL, Auchus RJ. Medroxyprogesterone acetate and dexamethasone are competitive inhibitors of different human steroidogenic enzymes. J Clin Endocrinol Metab 1999; 84:2104-2110.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2104-2110
    • Lee, T.C.1    Miller, W.L.2    Auchus, R.J.3
  • 11
    • 72449127495 scopus 로고    scopus 로고
    • Ovarian function and obesity-interrelationship, impact on women's reproductive lifespan and treatment options
    • Rachón D, Teede H. Ovarian function and obesity-interrelationship, impact on women's reproductive lifespan and treatment options. Mol Cell Endocrinol 2010; 316:172-179.
    • (2010) Mol Cell Endocrinol , vol.316 , pp. 172-179
    • Rachón, D.1    Teede, H.2
  • 12
    • 79955813822 scopus 로고    scopus 로고
    • Obesity and reproductive performance in women
    • Ogbuji QC. Obesity and reproductive performance in women. Afr J Reprod Health 2010; 14:143-151.
    • (2010) Afr J Reprod Health , vol.14 , pp. 143-151
    • Ogbuji, Q.C.1
  • 13
    • 77956199207 scopus 로고    scopus 로고
    • The adverse effects of obesity on conception and implantation
    • Brewer CJ, Balen AH. The adverse effects of obesity on conception and implantation. Reproduction 2010; 140:347-364.
    • (2010) Reproduction , vol.140 , pp. 347-364
    • Brewer, C.J.1    Balen, A.H.2
  • 14
    • 84861956278 scopus 로고    scopus 로고
    • National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications
    • Blencowe H, Cousens S, Oestergaard MZ, Chou D, Moller AB, Narwal R, Adler A, Vera Garcia C, Rohde S, Say L, Lawn JE. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 2012; 379:2162-2172.
    • (2012) Lancet , vol.379 , pp. 2162-2172
    • Blencowe, H.1    Cousens, S.2    Oestergaard, M.Z.3    Chou, D.4    Moller, A.B.5    Narwal, R.6    Adler, A.7    Vera Garcia, C.8    Rohde, S.9    Say, L.10    Lawn, J.E.11
  • 16
    • 42949086900 scopus 로고    scopus 로고
    • Maternal obesity: a problem for both mother and child
    • Rasmussen KM, Kjolhede CL. Maternal obesity: a problem for both mother and child. Obesity 2008; 16:929-931.
    • (2008) Obesity , vol.16 , pp. 929-931
    • Rasmussen, K.M.1    Kjolhede, C.L.2
  • 18
    • 0033925817 scopus 로고    scopus 로고
    • Obesity, insulin, sex steroids and ovulation
    • Nestler JE. Obesity, insulin, sex steroids and ovulation. Int J Obes Relat Metab Disord 2000; 24(suppl 2):S71-73.
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. S71-S73
    • Nestler, J.E.1
  • 19
    • 33748751562 scopus 로고    scopus 로고
    • Review article: The impact of obesity on reproduction in women with polycystic ovary syndrome
    • Pasquali R, Gambineri A, Pagotto U. Review article: The impact of obesity on reproduction in women with polycystic ovary syndrome. Br J Obstet Gynecol 2006; 113:1148-1159.
    • (2006) Br J Obstet Gynecol , vol.113 , pp. 1148-1159
    • Pasquali, R.1    Gambineri, A.2    Pagotto, U.3
  • 20
    • 72949100543 scopus 로고    scopus 로고
    • Inflammatory pathways in female reproductive health and disease
    • Jabbour HN, Sales KJ, Catalano RD, Norman JE. Inflammatory pathways in female reproductive health and disease. Reproduction 2009; 138: 903-919.
    • (2009) Reproduction , vol.138 , pp. 903-919
    • Jabbour, H.N.1    Sales, K.J.2    Catalano, R.D.3    Norman, J.E.4
  • 24
    • 78650324794 scopus 로고    scopus 로고
    • Extra- and intra-ovarian factors in polycystic ovary syndrome: impact on oocyte maturation and embryo developmental competence
    • Qiao J, Feng HL. Extra- and intra-ovarian factors in polycystic ovary syndrome: impact on oocyte maturation and embryo developmental competence. Hum Reprod Update 2011; 17:17-33.
    • (2011) Hum Reprod Update , vol.17 , pp. 17-33
    • Qiao, J.1    Feng, H.L.2
  • 25
    • 0029988804 scopus 로고    scopus 로고
    • Elevated interleukin-6 levels in the ovarian hyperstimulation syndrome: ovarian immunohistochemical localization of interleukin-6 signal
    • Loret de Mola JR, Flores JP, Baumgardner GP, Goldfarb JM, Gindlesperger V, Friedlander MA. Elevated interleukin-6 levels in the ovarian hyperstimulation syndrome: ovarian immunohistochemical localization of interleukin-6 signal. Obstet Gynecol 1996; 87:581-587.
    • (1996) Obstet Gynecol , vol.87 , pp. 581-587
    • Loret de Mola, J.R.1    Flores, J.P.2    Baumgardner, G.P.3    Goldfarb, J.M.4    Gindlesperger, V.5    Friedlander, M.A.6
  • 26
    • 0029788225 scopus 로고    scopus 로고
    • Ovarian hyperstimulation syndrome: pre-ovulatory serum concentrations of interleukin-6, interleukin-1 receptor antagonist and tumour necrosis factor-alpha cannot predict its occurrence
    • Loret de Mola JR, Baumgardner GP, Goldfarb JM, Friedlander MA. Ovarian hyperstimulation syndrome: pre-ovulatory serum concentrations of interleukin-6, interleukin-1 receptor antagonist and tumour necrosis factor-alpha cannot predict its occurrence. Hum Reprod 1996; 11: 1377-1380.
    • (1996) Hum Reprod , vol.11 , pp. 1377-1380
    • Loret de Mola, J.R.1    Baumgardner, G.P.2    Goldfarb, J.M.3    Friedlander, M.A.4
  • 27
    • 33846682591 scopus 로고    scopus 로고
    • The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells
    • Kulbe H, Thompson R, Wilson JL, Robinson S, Hagemann T, Fatah R, Gould D, Ayhan A, Balkwill F. The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells. Cancer Res 2007; 67:585-592.
    • (2007) Cancer Res , vol.67 , pp. 585-592
    • Kulbe, H.1    Thompson, R.2    Wilson, J.L.3    Robinson, S.4    Hagemann, T.5    Fatah, R.6    Gould, D.7    Ayhan, A.8    Balkwill, F.9
  • 28
    • 79957466111 scopus 로고    scopus 로고
    • Prognostic significance of IL-6 and IL-8 ascites levels in ovarian cancer patients
    • Lane D, Matte I, Rancourt C, Piché A. Prognostic significance of IL-6 and IL-8 ascites levels in ovarian cancer patients. BMC Cancer 2011; 11:210.
    • (2011) BMC Cancer , vol.11 , pp. 210
    • Lane, D.1    Matte, I.2    Rancourt, C.3    Piché, A.4
  • 29
    • 13444302907 scopus 로고    scopus 로고
    • Up-regulation of interleukin-6 in human ovarian cancer cell via a Gi/PI3KAkt/ NF-kappaB pathway by lysophosphatidic acid, an ovarian canceractivating factor
    • Chou CH, Wei LH, Kuo ML, Huang YJ, Lai KP, Chen CA, Hsieh CY. Up-regulation of interleukin-6 in human ovarian cancer cell via a Gi/PI3KAkt/ NF-kappaB pathway by lysophosphatidic acid, an ovarian canceractivating factor. Carcinogenesis 2005; 26:45-52.
    • (2005) Carcinogenesis , vol.26 , pp. 45-52
    • Chou, C.H.1    Wei, L.H.2    Kuo, M.L.3    Huang, Y.J.4    Lai, K.P.5    Chen, C.A.6    Hsieh, C.Y.7
  • 30
    • 0034079249 scopus 로고    scopus 로고
    • Elevated expression of tumour necrosis factor alpha in cultured granulosa cells from women with endometriosis
    • Carlberg M, Nejaty J, Fröysa B, Guan Y, Söder O, Bergqvist A. Elevated expression of tumour necrosis factor alpha in cultured granulosa cells from women with endometriosis. Hum Reprod 2000; 15:1250-1255.
    • (2000) Hum Reprod , vol.15 , pp. 1250-1255
    • Carlberg, M.1    Nejaty, J.2    Fröysa, B.3    Guan, Y.4    Söder, O.5    Bergqvist, A.6
  • 32
    • 0029004532 scopus 로고
    • Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur
    • Klebig ML, Wilkinson JE, Geisler JG, Woychik RP. Ectopic expression of the agouti gene in transgenic mice causes obesity, features of type II diabetes, and yellow fur. Proc Natl Acad Sci U S A 1995; 92:4728-4732.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4728-4732
    • Klebig, M.L.1    Wilkinson, J.E.2    Geisler, J.G.3    Woychik, R.P.4
  • 36
    • 84887992771 scopus 로고    scopus 로고
    • Diet-induced obesity alters immune cell infiltration and expression of inflammatory cytokine genes in mouse ovarian and peri-ovarian adipose depot tissues
    • Nteeba J, Ortinau LC, Perfield JW, Keating AF. Diet-induced obesity alters immune cell infiltration and expression of inflammatory cytokine genes in mouse ovarian and peri-ovarian adipose depot tissues. Mol Reprod Develop 2013; 80:948-958.
    • (2013) Mol Reprod Develop , vol.80 , pp. 948-958
    • Nteeba, J.1    Ortinau, L.C.2    Perfield, J.W.3    Keating, A.F.4
  • 37
    • 41949105511 scopus 로고    scopus 로고
    • Impact of obesity on female fertility and fertility treatment
    • Zain MM, Norman RJ. Impact of obesity on female fertility and fertility treatment. Womens Health (Lond Engl) 2008; 4:183-194.
    • (2008) Womens Health (Lond Engl) , vol.4 , pp. 183-194
    • Zain, M.M.1    Norman, R.J.2
  • 38
    • 0031835060 scopus 로고    scopus 로고
    • Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment
    • Clark AM, Thornley B, Tomlinson L, Galletley C, Norman RJ. Weight loss in obese infertile women results in improvement in reproductive outcome for all forms of fertility treatment. Hum Reprod 1998; 13: 1502-1505.
    • (1998) Hum Reprod , vol.13 , pp. 1502-1505
    • Clark, A.M.1    Thornley, B.2    Tomlinson, L.3    Galletley, C.4    Norman, R.J.5
  • 42
    • 0018343872 scopus 로고
    • The association of obesity with infertility and related menstrual abnormalities in women
    • Hartz AJ, Barboriak PN, Wong A, Katayama KP, Rimm AA. The association of obesity with infertility and related menstrual abnormalities in women. Int J Obes 1979; 3:57-73.
    • (1979) Int J Obes , vol.3 , pp. 57-73
    • Hartz, A.J.1    Barboriak, P.N.2    Wong, A.3    Katayama, K.P.4    Rimm, A.A.5
  • 43
    • 0028843928 scopus 로고
    • Weight loss results in significant improvement in pregnancy and ovulation rates in anovulatory obese women
    • Clark AM, Ledger W, Galletly C, Tomlinson L, Blaney F, Wang X, Norman RJ. Weight loss results in significant improvement in pregnancy and ovulation rates in anovulatory obese women. Hum Reprod 1995; 10: 2705-2712.
    • (1995) Hum Reprod , vol.10 , pp. 2705-2712
    • Clark, A.M.1    Ledger, W.2    Galletly, C.3    Tomlinson, L.4    Blaney, F.5    Wang, X.6    Norman, R.J.7
  • 44
    • 84884907518 scopus 로고    scopus 로고
    • Obesity reduces uterine receptivity: clinical experience from 9, 587 first cycles of ovum donation with normal weight donors
    • Bellver J, Pellicer A, Garcia-Velasco JA, Ballesteros A, Remohi J, Meseguer M. Obesity reduces uterine receptivity: clinical experience from 9, 587 first cycles of ovum donation with normal weight donors. Fertil Steril 2013; 100:1050-1058.
    • (2013) Fertil Steril , vol.100 , pp. 1050-1058
    • Bellver, J.1    Pellicer, A.2    Garcia-Velasco, J.A.3    Ballesteros, A.4    Remohi, J.5    Meseguer, M.6
  • 46
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444: 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 47
    • 34548639473 scopus 로고    scopus 로고
    • Obesity-induced inflammation: a metabolic dialogue in the language of inflammation
    • Ferrante AW. Obesity-induced inflammation: a metabolic dialogue in the language of inflammation. J Intern Med 2007; 262:408-414.
    • (2007) J Intern Med , vol.262 , pp. 408-414
    • Ferrante, A.W.1
  • 48
    • 84855955819 scopus 로고    scopus 로고
    • Genes involved in the immediate early response and epithelial-mesenchymal transition are regulated by adipocytokines in the female reproductive tract
    • Yang Z, Norwood KA, Smith JE, Kerl JG, Wood JR. Genes involved in the immediate early response and epithelial-mesenchymal transition are regulated by adipocytokines in the female reproductive tract. Mol Reprod Dev 2012; 79:128-137.
    • (2012) Mol Reprod Dev , vol.79 , pp. 128-137
    • Yang, Z.1    Norwood, K.A.2    Smith, J.E.3    Kerl, J.G.4    Wood, J.R.5
  • 51
    • 0022686988 scopus 로고
    • Effects of obesity on insulin and glucose metabolism in cyclic heifers
    • McCann JP, Reimers TJ. Effects of obesity on insulin and glucose metabolism in cyclic heifers. J Anim Sci 1986; 62:772-782.
    • (1986) J Anim Sci , vol.62 , pp. 772-782
    • McCann, J.P.1    Reimers, T.J.2
  • 52
    • 77954953291 scopus 로고    scopus 로고
    • Obesity and reproductive hormone levels in the transition to menopause
    • Freeman EW, Sammel MD, Lin H, Gracia CR. Obesity and reproductive hormone levels in the transition to menopause. Menopause 2010; 17: 718-726.
    • (2010) Menopause , vol.17 , pp. 718-726
    • Freeman, E.W.1    Sammel, M.D.2    Lin, H.3    Gracia, C.R.4
  • 53
  • 55
    • 84897481540 scopus 로고    scopus 로고
    • Impact of obesity on ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene in mice
    • Nteeba J, Ganesan S, Keating AF. Impact of obesity on ovotoxicity induced by 7, 12-dimethylbenz[a]anthracene in mice. Biol Reprod 2014; 90:68.
    • (2014) Biol Reprod , vol.90 , pp. 68
    • Nteeba, J.1    Ganesan, S.2    Keating, A.F.3
  • 58
    • 0037188816 scopus 로고    scopus 로고
    • Insulin but not insulin-like growth factor-1 promotes the primordial to primary follicle transition
    • Kezele PR, Nilsson EE, Skinner MK. Insulin but not insulin-like growth factor-1 promotes the primordial to primary follicle transition. Mol Cell Endocrinol 2002; 192:37-43.
    • (2002) Mol Cell Endocrinol , vol.192 , pp. 37-43
    • Kezele, P.R.1    Nilsson, E.E.2    Skinner, M.K.3
  • 59
    • 0042315398 scopus 로고    scopus 로고
    • Regulation of ovarian primordial follicle assembly and development by estrogen and progesterone: endocrine model of follicle assembly
    • Kezele P, Skinner MK. Regulation of ovarian primordial follicle assembly and development by estrogen and progesterone: endocrine model of follicle assembly. Endocrinol 2003; 144:3329-3337.
    • (2003) Endocrinol , vol.144 , pp. 3329-3337
    • Kezele, P.1    Skinner, M.K.2
  • 62
    • 34547118106 scopus 로고    scopus 로고
    • Estradiol, progesterone, and genistein inhibit oocyte nest breakdown and primordial follicle assembly in the neonatal mouse ovary in vitro and in vivo
    • Chen Y, Jefferson WN, Newbold RR, Padilla-Banks E, Pepling ME. Estradiol, progesterone, and genistein inhibit oocyte nest breakdown and primordial follicle assembly in the neonatal mouse ovary in vitro and in vivo. Endocrinol 2007; 148:3580-3590.
    • (2007) Endocrinol , vol.148 , pp. 3580-3590
    • Chen, Y.1    Jefferson, W.N.2    Newbold, R.R.3    Padilla-Banks, E.4    Pepling, M.E.5
  • 63
    • 32844475300 scopus 로고    scopus 로고
    • Stem cell factor (SCF)-kit mediated phosphatidylinositol 3 (PI3) kinase signaling during mammalian oocyte growth and early follicular development
    • Liu K. Stem cell factor (SCF)-kit mediated phosphatidylinositol 3 (PI3) kinase signaling during mammalian oocyte growth and early follicular development. Front Biosci 2006; 11:126-135.
    • (2006) Front Biosci , vol.11 , pp. 126-135
    • Liu, K.1
  • 64
    • 84883307792 scopus 로고    scopus 로고
    • High fat diet induced obesity alters ovarian phosphatidylinositol-3 kinase signaling gene expression
    • Nteeba J, Ross JW, Perfield Ii JW, Keating AF. High fat diet induced obesity alters ovarian phosphatidylinositol-3 kinase signaling gene expression. Reprod Toxicol 2013; 42:68-77.
    • (2013) Reprod Toxicol , vol.42 , pp. 68-77
    • Nteeba, J.1    Ross, J.W.2    Perfield Ii, J.W.3    Keating, A.F.4
  • 65
    • 84878404399 scopus 로고    scopus 로고
    • Insulin directly regulates steroidogenesis via induction of the orphan nuclear receptor DAX-1 in testicular Leydig cells
    • Ahn SW, Gang G-T, Kim YD, Ahn R-S, Harris RA, Lee C-H, Choi H-S. Insulin directly regulates steroidogenesis via induction of the orphan nuclear receptor DAX-1 in testicular Leydig cells. J Biol Chem 2013; 288: 15937-15946.
    • (2013) J Biol Chem , vol.288 , pp. 15937-15946
    • Ahn, S.W.1    Gang, G.-T.2    Kim, Y.D.3    Ahn, R.-S.4    Harris, R.A.5    Lee, C.-H.6    Choi, H.-S.7
  • 66
    • 0021995144 scopus 로고
    • Effect of insulin on porcine granulosa cells: implications of a possible receptor mediated action
    • Otani T, Maruo T, Yukimura N, Mochizuki M. Effect of insulin on porcine granulosa cells: implications of a possible receptor mediated action. Acta Endocrinol (Copenh) 1985; 108:104-110.
    • (1985) Acta Endocrinol (Copenh) , vol.108 , pp. 104-110
    • Otani, T.1    Maruo, T.2    Yukimura, N.3    Mochizuki, M.4
  • 67
    • 0029328269 scopus 로고
    • The ovarian insulin and insulin-like growth factor system with an emphasis on domestic animals
    • Spicer LJ, Echternkamp SE. The ovarian insulin and insulin-like growth factor system with an emphasis on domestic animals. Domest Anim Endocrinol 1995; 12:223-245.
    • (1995) Domest Anim Endocrinol , vol.12 , pp. 223-245
    • Spicer, L.J.1    Echternkamp, S.E.2
  • 68
    • 0038076237 scopus 로고    scopus 로고
    • Energetics and reproductive effort
    • Ellison PT. Energetics and reproductive effort. Am J Hum Biol 2003; 15: 342-351.
    • (2003) Am J Hum Biol , vol.15 , pp. 342-351
    • Ellison, P.T.1
  • 69
    • 84876722233 scopus 로고    scopus 로고
    • Relationships between biomarkers of inflammation, ovarian steroids, and age at menarche in a rural Polish sample
    • Clancy KB, Klein LD, Ziomkiewicz A, Nenko I, Jasienska G, Bribiescas RG. Relationships between biomarkers of inflammation, ovarian steroids, and age at menarche in a rural Polish sample. Am J Hum Biol 2013; 25: 389-398.
    • (2013) Am J Hum Biol , vol.25 , pp. 389-398
    • Clancy, K.B.1    Klein, L.D.2    Ziomkiewicz, A.3    Nenko, I.4    Jasienska, G.5    Bribiescas, R.G.6
  • 70
    • 79957977553 scopus 로고    scopus 로고
    • Obesity is associated with a higher level of proinflammatory cytokines in follicular fluid of women undergoing medically assisted procreation (PMA) programs
    • La Vignera S, Condorelli R, Bellanca S, La Rosa B, Mousaví A, Busà B, Vicari LO, Vicari E. Obesity is associated with a higher level of proinflammatory cytokines in follicular fluid of women undergoing medically assisted procreation (PMA) programs. Eur Rev Med Pharmacol Sci 2011; 15:267-273.
    • (2011) Eur Rev Med Pharmacol Sci , vol.15 , pp. 267-273
    • La Vignera, S.1    Condorelli, R.2    Bellanca, S.3    La Rosa, B.4    Mousaví, A.5    Busà, B.6    Vicari, L.O.7    Vicari, E.8
  • 71
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995; 95:2409-2415.
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 72
    • 0028968879 scopus 로고
    • The expression of tumor necrosis factor in human adipose tissue Regulation by obesity, weight loss, and relationship to lipoprotein lipase.
    • Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB. The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 1995; 95:2111-2119.
    • (1995) J Clin Invest , vol.95 , pp. 2111-2119
    • Kern, P.A.1    Saghizadeh, M.2    Ong, J.M.3    Bosch, R.J.4    Deem, R.5    Simsolo, R.B.6
  • 73
    • 0030028606 scopus 로고    scopus 로고
    • The expression of TNF alpha by human muscle Relationship to insulin resistance.
    • Saghizadeh M, Ong JM, Garvey WT, Henry RR, Kern PA. The expression of TNF alpha by human muscle. Relationship to insulin resistance. J Clin Invest 1996; 97:1111-1116.
    • (1996) J Clin Invest , vol.97 , pp. 1111-1116
    • Saghizadeh, M.1    Ong, J.M.2    Garvey, W.T.3    Henry, R.R.4    Kern, P.A.5
  • 74
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993; 259:87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 75
    • 0027972524 scopus 로고
    • Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance
    • Hofmann C, Lorenz K, Braithwaite SS, Colca JR, Palazuk BJ, Hotamisligil GS, Spiegelman BM. Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance. Endocrinol 1994; 134:264-270.
    • (1994) Endocrinol , vol.134 , pp. 264-270
    • Hofmann, C.1    Lorenz, K.2    Braithwaite, S.S.3    Colca, J.R.4    Palazuk, B.J.5    Hotamisligil, G.S.6    Spiegelman, B.M.7
  • 76
    • 0029340581 scopus 로고
    • [Effect of interleukin-2 and interleukin-6 on ovary in the ovulatory period-establishment of the new ovarian perfusion system and influence of interleukins on ovulation rate and steroid secretion]
    • Mikuni M. [Effect of interleukin-2 and interleukin-6 on ovary in the ovulatory period-establishment of the new ovarian perfusion system and influence of interleukins on ovulation rate and steroid secretion]. Hokkaido Igaku Zasshi 1995; 70:561-572.
    • (1995) Hokkaido Igaku Zasshi , vol.70 , pp. 561-572
    • Mikuni, M.1
  • 77
    • 0031978447 scopus 로고    scopus 로고
    • Effects of interleukin (IL)-6 on luteinizing hormone- and IL-1beta-induced ovulation and steroidogenesis in the rat ovary
    • Van der Hoek KH, Woodhouse CM, Brännström M, Norman RJ. Effects of interleukin (IL)-6 on luteinizing hormone- and IL-1beta-induced ovulation and steroidogenesis in the rat ovary. Biol Reprod 1998; 58: 1266-1271.
    • (1998) Biol Reprod , vol.58 , pp. 1266-1271
    • Van der Hoek, K.H.1    Woodhouse, C.M.2    Brännström, M.3    Norman, R.J.4
  • 78
    • 0025184072 scopus 로고
    • Immunological evidence for a human ovarian tumor necrosis factor-alpha
    • Roby KF, Weed J, Lyles R, Terranova PF. Immunological evidence for a human ovarian tumor necrosis factor-alpha. J Clin Endocrinol Metab 1990; 71:1096-1102.
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 1096-1102
    • Roby, K.F.1    Weed, J.2    Lyles, R.3    Terranova, P.F.4
  • 79
    • 0025773340 scopus 로고
    • Cytokine-mediated regulation of ovarian function. Tumor necrosis factor alpha inhibits gonadotropin-supported ovarian androgen biosynthesis.
    • Andreani CL, Payne DW, Packman JN, Resnick CE, Hurwitz A, Adashi EY. Cytokine-mediated regulation of ovarian function. Tumor necrosis factor alpha inhibits gonadotropin-supported ovarian androgen biosynthesis. J Biol Chem 1991; 266:6761-6766.
    • (1991) J Biol Chem , vol.266 , pp. 6761-6766
    • Andreani, C.L.1    Payne, D.W.2    Packman, J.N.3    Resnick, C.E.4    Hurwitz, A.5    Adashi, E.Y.6
  • 82
    • 0033863752 scopus 로고    scopus 로고
    • Relationships between concentrations of tumor necrosis factor-alpha and nitric oxide in follicular fluid and oocyte quality
    • Lee KS, Joo BS, Na YJ, Yoon MS, Choi OH, Kim WW. Relationships between concentrations of tumor necrosis factor-alpha and nitric oxide in follicular fluid and oocyte quality. J Assist Reprod Genet 2000; 17: 222-228.
    • (2000) J Assist Reprod Genet , vol.17 , pp. 222-228
    • Lee, K.S.1    Joo, B.S.2    Na, Y.J.3    Yoon, M.S.4    Choi, O.H.5    Kim, W.W.6
  • 83
    • 0036153776 scopus 로고    scopus 로고
    • Inducible and endothelial nitric oxide synthase: genetic background affects ovulation in mice
    • Hefler LA, Gregg AR. Inducible and endothelial nitric oxide synthase: genetic background affects ovulation in mice. Fertil Steril 2002; 77: 147-151.
    • (2002) Fertil Steril , vol.77 , pp. 147-151
    • Hefler, L.A.1    Gregg, A.R.2
  • 86
    • 28244443591 scopus 로고    scopus 로고
    • Oxidative stress and its implications in female infertility-a clinician's perspective
    • Agarwal A, Gupta S, Sharma R. Oxidative stress and its implications in female infertility-a clinician's perspective. Reprod Biomed Online 2005; 11:641-650.
    • (2005) Reprod Biomed Online , vol.11 , pp. 641-650
    • Agarwal, A.1    Gupta, S.2    Sharma, R.3
  • 87
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-jB activation pathways and their role in innate and adaptive immunity
    • Bonizzi G, Karin M. The two NF-jB activation pathways and their role in innate and adaptive immunity. Trends Immunol 2004; 25:280-288.
    • (2004) Trends Immunol , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 88
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS, Ghosh S. Signaling to NF-kappaB. Genes Dev 2004; 18: 2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 89
    • 0033216629 scopus 로고    scopus 로고
    • NF-kappaB as a primary regulator of the stress response
    • Mercurio F, Manning AM. NF-kappaB as a primary regulator of the stress response. Oncogene 1999; 18:6163-6171.
    • (1999) Oncogene , vol.18 , pp. 6163-6171
    • Mercurio, F.1    Manning, A.M.2
  • 90
    • 75749094013 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-alpha on porcine oocyte meiosis progression, spindle organization, and chromosome alignment
    • Ma CH, Yan LY, Qiao J, Sha W, Li L, Chen Y, Sun QY. Effects of tumor necrosis factor-alpha on porcine oocyte meiosis progression, spindle organization, and chromosome alignment. Fertil Steril 2010; 93:920-926.
    • (2010) Fertil Steril , vol.93 , pp. 920-926
    • Ma, C.H.1    Yan, L.Y.2    Qiao, J.3    Sha, W.4    Li, L.5    Chen, Y.6    Sun, Q.Y.7
  • 91
    • 84858718448 scopus 로고    scopus 로고
    • NF-kappaB and the link between inflammation and cancer
    • DiDonato J, Mercurio F, Karin M. NF-kappaB and the link between inflammation and cancer. Immunol Rev 2012; 246:379-400.
    • (2012) Immunol Rev , vol.246 , pp. 379-400
    • DiDonato, J.1    Mercurio, F.2    Karin, M.3


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