Insulin directly regulates steroidogenesis via induction of the orphan nuclear receptor DAX-1 in testicular Leydig cells

Journal of Biological Chemistry

Volumn 288, Issue 22, 2013, Pages 15937-15946

  Ahn, Seung Won ^a   Gang, Gil Tae ^b   Kim, Yong Deuk ^a   Ahn, Ryun Sup ^c   Harris, Robert A ^d   Lee, Chul Ho ^b   Choi, Hueng Sik ^a,e  

^a Chonnam National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c CHA University   (South Korea)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Chonnam National University Medical School   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CRITICAL REGION; DIET-INDUCED OBESITY; INSULIN RECEPTORS; INSULIN RESISTANCE; LUTEINIZING HORMONES; NUCLEAR RECEPTORS; REGULATORY MECHANISM; TYPE-2 DIABETES;

CELL CULTURE; CELL MEMBRANES; ENZYMES; GENE EXPRESSION; MAMMALS; NUTRITION;

INSULIN;

CYCLIC AMP; FOLLITROPIN; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; LIVER RECEPTOR HOMOLOG 1; LUTEINIZING HORMONE; NUCLEAR RECEPTOR DAX 1; ORPHAN NUCLEAR RECEPTOR; PHOSPHOINSULIN RECEPTOR BETA; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADRENAL DISEASE; ADRENAL HYPOPLASIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CELL STRAIN; CELL STRAIN MA 10; CONTROLLED STUDY; GENE EXPRESSION; HORMONE ACTION; HUMAN; HUMAN CELL; HYPOPLASIA; LEYDIG CELL; LIPID DIET; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEROIDOGENESIS; X CHROMOSOME;

DAX-1; DIABETES; INSULIN; INSULIN RESISTANCE; NUCLEAR RECEPTORS; STEROIDOGENESIS;

ANIMALS; CELL LINE; DAX-1 ORPHAN NUCLEAR RECEPTOR; DIETARY FATS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GONADAL STEROID HORMONES; INSULIN; INSULIN RESISTANCE; LEYDIG CELLS; MALE; MICE; OBESITY; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

MUS;

EID: 84878404399     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.451773     Document Type: Article

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