Mechanistic analysis of nonoxygenated hypothermic machine perfusion's protection on warm ischemic kidney uncovers greater enos phosphorylation and vasodilation

American Journal of Transplantation

Volumn 14, Issue 11, 2014, Pages 2500-2514

  Chatauret, N ^a,b,c   Coudroy, R ^a,b,c   Delpech, P O ^a,b   Vandebrouck, C ^d   Hosni, S ^a,b   Scepi, M ^a,b,c   Hauet, T ^a,b,c,e,f  

^a INSERM   (France)

^b UNIVERSITÉ DE POITIERS   (France)

^c POITIERS UNIVERSITY HOSPITAL   (France)

^d France   (France)

^e CEMAGREF   (France)

^f Fédération Hospitalo Universitaires SUPORT Limoges Poitiers Tours   (France)

Author keywords

Basic (laboratory) research science; cellular biology; donors and donation: donation after circulatory death (DCD); ischemia reperfusion injury (IRI); kidney transplantation nephrology; organ perfusion and preservation

Indexed keywords

ADENYLATE KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; KRUPPEL LIKE FACTOR 2; NITRIC OXIDE; PROTEIN KINASE B; UNIVERSITY OF WISCONSIN SOLUTION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYOPRESERVATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; IN VIVO STUDY; KIDNEY CIRCULATION; KIDNEY CORTEX; KIDNEY GRAFT; KIDNEY ISCHEMIA; KIDNEY PERFUSION; KIDNEY TRANSPLANTATION; LASER DOPPLER FLOWMETRY; MALE; MICROCIRCULATION; NONHUMAN; NONOXYGENATED HYPOTHERMIC MACHINE PERFUSION; PORCINE MODEL; PROTEIN EXPRESSION; RENAL ARTERY; RENAL PROTECTION; REPERFUSION; SIGNAL TRANSDUCTION; TISSUE LEVEL; VASCULAR ENDOTHELIUM; VASODILATATION; ANIMAL; ENZYMOLOGY; INDUCED HYPOTHERMIA; ISCHEMIA; KIDNEY; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PIG; VASCULARIZATION;

ANIMALS; HYPOTHERMIA, INDUCED; ISCHEMIA; KIDNEY; MALE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; REPERFUSION; SWINE; VASODILATION;

EID: 84911389275     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12904     Document Type: Article

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