MicroRNA dysregulation, gene networks and risk for schizophrenia in 22q11.2 deletion syndrome

Frontiers in Neurology

Volumn 5, Issue NOV, 2014, Pages

  Merico, Daniele ^a   Costain, Gregory ^b   Butcher, Nancy J ^b,c   Warnica, William ^b   Ogura, Lucas ^b   Alfred, Simon E ^b   Brzustowicz, Linda M ^d   Bassett, Anne S ^b,c,e,f,g  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d Life Sciences Building Rutgers University   (United States)

^e TORONTO GENERAL HOSPITAL   (Canada)

^f UNIVERSITY HEALTH NETWORK   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

22q11 deletion syndrome; 22q11.2; Congenital cardiac defect; DGCR8; DiGeorge syndrome; Disease gene prediction; DLGAP; Dopamine; Gene dosage; Glutamate; GRIA1; microRNA; miR 1286; miR 1306; miR 185; miR 3618; miR 4761; miR 649; miR 6816; Pathway analysis; Protein interaction network; Schizophrenia; Synapse

Indexed keywords

BONE MORPHOGENETIC PROTEIN; MICRORNA; MICRORNA 1286; MICRORNA 1306; MICRORNA 185; MICRORNA 3618; MICRORNA 4761; MICRORNA 649; MICRORNA 6816; MITOGEN ACTIVATED PROTEIN KINASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ARTICLE; BRAIN FUNCTION; CHROMOSOME DELETION 22Q11; COPY NUMBER VARIATION; DGCR8 GENE; GENE; GENE DOSAGE; GENE FUNCTION; GENE MAPPING; GENE TARGETING; GENETIC ANALYSIS; GENETIC PREDISPOSITION; GENETIC REGULATION; HEMIZYGOSITY; HUMAN; NONHUMAN; PROTEIN INTERACTION; RISK ASSESSMENT; SCHIZOPHRENIA; SIGNAL TRANSDUCTION;

EID: 84911364655     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2014.00238     Document Type: Article

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