Hypothesis-independent pathway analysis implicates GABA and Acetyl-CoA metabolism in primary open-angle glaucoma and normal-pressure glaucoma

Human Genetics

Volumn 133, Issue 10, 2014, Pages 1319-1330

  Bailey, Jessica N Cooke ^a,t   Yaspan, Brian L ^a,u   Pasquale, Louis R ^b   Hauser, Michael A ^c   Kang, Jae H ^b   Loomis, Stephanie J ^b   Brilliant, Murray ^d   Budenz, Donald L ^e   Christen, William G ^f   Fingert, John ^g   Gaasterland, Douglas ^h   Gaasterland, Terry ⁱ   Kraft, Peter ^j   Lee, Richard K ^k   Lichter, Paul R ^l   Liu, Yutao ^c   McCarty, Catherine A ^m   Moroi, Sayoko E ^l   Richards, Julia E ^l   Realini, Tony ⁿ   Schuman, Joel S ^o   Scott, William K ^p   Singh, Kuldev ^q   Sit, Arthur J ^r   Vollrath, Douglas ^q   Wollstein, Gadi ^o   Zack, Donald J ^s   Zhang, Kang ⁱ   Pericak Vance, Margaret A ^p   Allingham, R Rand ^c   Weinreb, Robert N ⁱ   Haines, Jonathan L ^a,t   Wiggs, Janey L ^b   more..

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d MARSHFIELD CLINIC   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g UNIVERSITY OF IOWA   (United States)

^h Eye Doctors of Washington   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^k UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^l UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^m ESSENTIA INSTITUTE OF RURAL HEALTH   (United States)

ⁿ West Virginia University Eye Institute   (United States)

^o UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^p UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^q STANFORD UNIVERSITY   (United States)

^r MAYO CLINIC   (United States)

^s JOHNS HOPKINS UNIVERSITY   (United States)

^t CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^u GENENTECH INC   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID; 4 AMINOBUTYRIC ACID; ACETYL COENZYME A; ALDEHYDE DEHYDROGENASE; HLA ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLALANINE; SONIC HEDGEHOG PROTEIN; TRYPTOPHAN; TYROSINE;

ALLELE; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; ENZYME METABOLISM; GENETIC ALGORITHM; GENETIC ASSOCIATION; GLAUCOMA; HEMATOPOIETIC CELL; HUMAN; INTRAOCULAR PRESSURE; MAJOR CLINICAL STUDY; MULTIGENE FAMILY; NORMAL PRESSURE GLAUCOMA; OPEN ANGLE GLAUCOMA; PATHOGENESIS; PATHWAY ANALYSIS BY RANDOMIZATION INCORPORATING STRUCTURE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; BIOLOGICAL MODEL; CASE CONTROL STUDY; CLUSTER ANALYSIS; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; METABOLISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ERINACEIDAE;

ACETYL COENZYME A; CASE-CONTROL STUDIES; CLUSTER ANALYSIS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GENETIC PREDISPOSITION TO DISEASE; GLAUCOMA; GLAUCOMA, OPEN-ANGLE; HUMANS; INTRAOCULAR PRESSURE; MALE; METABOLIC NETWORKS AND PATHWAYS; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84911001878     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-014-1468-7     Document Type: Article

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