메뉴 건너뛰기




Volumn 15, Issue 18, 2014, Pages 2741-2749

Luseogliflozin for the treatment of type 2 diabetes

Author keywords

Luseogliflozin; Sodium glucose cotransport; Sodium glucose cotransporter 2 inhibitor; Type 2 diabetes mellitus

Indexed keywords

LUSEOGLIFLOZIN; PLACEBO; 1,5-ANHYDRO-1-(5-(4-ETHOXYBENZYL)-2-METHOXY-4-METHYLPHENYL)-1-THIOGLUCITOL; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; SODIUM GLUCOSE COTRANSPORTER 2; SORBITOL;

EID: 84910685028     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1517/14656566.2014.978290     Document Type: Article
Times cited : (30)

References (31)
  • 1
    • 77951199006 scopus 로고    scopus 로고
    • 6th edition. Available from[Last accessed 29 January 2014]
    • International Diabetes Federation. IDF Diabetes Atlas. 6th edition. Available from: http://www.idf.org/diabetesatlas/[Last accessed 29 January 2014]
    • International Diabetes Federation IDF Diabetes Atlas
  • 2
    • 84866268783 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes: A patient-centered approach position statement of the american diabetes association ada and the european association for the study of diabetes (easd
    • Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes: a patient-centered approach position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012;35: 1364-79
    • (2012) Diabetes Care , vol.35 , pp. 1364-1379
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 3
    • 84890566037 scopus 로고    scopus 로고
    • American association of clinical endocrinologists' comprehensive diabetes management algorithm 2013 consensus statement
    • Garber AJ, Abrahamson M, Barzilay J, et al. American Association of Clinical Endocrinologists' comprehensive diabetes management algorithm 2013 consensus statement. Endocr Pract 2013;19: 536-57
    • (2013) Endocr Pract , vol.19 , pp. 536-557
    • Garber, A.J.1    Abrahamson, M.2    Barzilay, J.3
  • 4
    • 84856740961 scopus 로고    scopus 로고
    • Oral pharmacologic treatment of type 2 diabetes mellitus: A clinical practice guideline from the american college of physicians
    • Qaseem A, Humphrey LL, Sweet DE, et al. Oral pharmacologic treatment of type 2 diabetes mellitus: a clinical practice guideline from the American College of Physicians. Ann Intern Med 2012;156: 218-31
    • (2012) Ann Intern Med , vol.156 , pp. 218-231
    • Qaseem, A.1    Humphrey, L.L.2    Sweet, D.E.3
  • 5
    • 84857226676 scopus 로고    scopus 로고
    • DPP-4 inhibition and islet function
    • Ahren B. DPP-4 inhibition and islet function. J Diabetes Investig 2012;3: 3-10
    • (2012) J Diabetes Investig , vol.3 , pp. 3-10
    • Ahren, B.1
  • 6
    • 84878360808 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide and glucagonlike peptide-1: Incretin actions beyond the pancreas
    • Seino Y, Yabe D. Glucose-dependent insulinotropic polypeptide and glucagonlike peptide-1: incretin actions beyond the pancreas. J Diabetes Investig 2013;4: 108-30
    • (2013) J Diabetes Investig , vol.4 , pp. 108-130
    • Seino, Y.1    Yabe, D.2
  • 7
    • 84856751751 scopus 로고    scopus 로고
    • Association of hba1c levels with vascular complications and death in patients with type 2 diabetes: Evidence of glycaemic thresholds
    • Zoungas S, Chalmers J, Ninomiya T, et al. Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Diabetologia 2012;55: 636-43
    • (2012) Diabetologia , vol.55 , pp. 636-643
    • Zoungas, S.1    Chalmers, J.2    Ninomiya, T.3
  • 8
    • 84869745717 scopus 로고    scopus 로고
    • Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes
    • Clar C, Gill JA, Court R, et al. Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes. BMJ Open 2012;2: e001007
    • (2012) BMJ Open , vol.2 , pp. e001007
    • Clar, C.1    Gill, J.A.2    Court, R.3
  • 9
    • 79961228970 scopus 로고    scopus 로고
    • Ts-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (sglt2) inhibitor with antihyperglycaemic activity
    • Yamamoto K, Uchida S, Kitano K, et al. TS-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with antihyperglycaemic activity. Br J Pharmacol 2011;164: 181-91
    • (2011) Br J Pharmacol , vol.164 , pp. 181-191
    • Yamamoto, K.1    Uchida, S.2    Kitano, K.3
  • 10
    • 84860183617 scopus 로고    scopus 로고
    • A novel approach to control hyperglycemia in type 2 diabetes: Sodium glucose co-Transport (SGLT) inhibitors: Systematic review and meta-Analysis of randomized trials
    • Musso G, Gambino R, Cassader M, et al. A novel approach to control hyperglycemia in type 2 diabetes: sodium glucose co-Transport (SGLT) inhibitors: systematic review and meta-Analysis of randomized trials. Ann Med 2012;44: 375-93
    • (2012) Ann Med , vol.44 , pp. 375-393
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 11
    • 84877922239 scopus 로고    scopus 로고
    • Ipragliflozin and other sodium-glucose cotransporter-2 (sglt2) inhibitors in the treatment of type 2 diabetes: Preclinical and clinical data
    • Kurosaki E, Ogasawara H. Ipragliflozin and other sodium-glucose cotransporter-2 (SGLT2) inhibitors in the treatment of type 2 diabetes: preclinical and clinical data. Pharmacol Ther 2013;139: 51-9
    • (2013) Pharmacol Ther , vol.139 , pp. 51-59
    • Kurosaki, E.1    Ogasawara, H.2
  • 13
    • 77951143723 scopus 로고    scopus 로고
    • 1S-1, 5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-Thio-Dglucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment
    • Kakinuma H, Oi T, Hashimoto-Tsuchiya Y, et al. (1S)-1, 5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-Thio-Dglucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment. J Med Chem 2010;53: 3247-61
    • (2010) J Med Chem , vol.53 , pp. 3247-3261
    • Kakinuma, H.1    Oi, T.2    Hashimoto-Tsuchiya, Y.3
  • 14
    • 84910597695 scopus 로고    scopus 로고
    • Tokyo: Taisho Pharmaceutical Co., Ltd., 2014. Available from[Last accessed 12 August 2014] In Japanese
    • Lusefi-Tablets 2.5/5 mg package insert. Tokyo: Taisho Pharmaceutical Co., Ltd., 2014. Available from: http://www.info. pmda.go.jp/go/pack/3969020F1020-1-01/[Last accessed 12 August 2014]; In Japanese
    • Lusefi-Tablets 2.5/5 Mg Package Insert
  • 15
    • 84910654569 scopus 로고    scopus 로고
    • Pharmacokinetics and prediction of drug-drug interaction of ts-071 a selective sglt2 inhibitor
    • 16-18 November 2011; Hiroshima, Japan;. Poster Session 2-P2-28
    • Chino Y, Hasegawa M, Hachiuma K, et al. Pharmacokinetics and prediction of drug-drug interaction of TS-071 a selective SGLT2 inhibitor. 26th JSSX Annual Meeting; 16-18 November 2011; Hiroshima, Japan;. Poster Session 2-P2-28
    • 26th JSSX Annual Meeting
    • Chino, Y.1    Hasegawa, M.2    Hachiuma, K.3
  • 17
    • 84910635281 scopus 로고    scopus 로고
    • Tokyo: Taisho Pharmaceutical Co., Ltd., 2014. Available from[Last accessed 12 August 2014] In Japanese
    • The pharmaceutical interview form, supplemental to the package insert for Lusefi-Tablets 2.5/5 mg. Tokyo: Taisho Pharmaceutical Co., Ltd., 2014. Available from: http://www.info. pmda.go.jp/go/pack/3969020F1020-1-01/[Last accessed 12 August 2014]; In Japanese
    • Pharmaceutical Interview Form, Supplemental to the Package Insert for Lusefi-Tablets 2.5/5 Mg
  • 18
    • 84898890575 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and pharmacodynamics of single and multiple luseogliflozin dosing in healthy japanese males: A randomized, single-blind, placebo-controlled trial
    • Sasaki T, Seino Y, Fukatsu A, et al. Safety, pharmacokinetics, and pharmacodynamics of single and multiple luseogliflozin dosing in healthy japanese males: a randomized, single-blind, placebo-controlled trial. Adv Ther 2014;31: 345-61
    • (2014) Adv Ther , vol.31 , pp. 345-361
    • Sasaki, T.1    Seino, Y.2    Fukatsu, A.3
  • 19
    • 84910620581 scopus 로고    scopus 로고
    • Ts-071, a novel potent and highly selective renal sodium-glucose co-Transporter 2 (sglt2) inhibitor, increases urinary glucose excretion and reduces plasma glucose levels in japanese patients with type 2 diabetes mellitus
    • Annual Meeting; 12-16 September 2011; Lisbon, Portugal; Poster 846
    • Sasaki T, Seino Y, Fukatsu A, et al. TS-071, a novel potent and highly selective renal sodium-glucose co-Transporter 2 (SGLT2) inhibitor, increases urinary glucose excretion and reduces plasma glucose levels in Japanese patients with type 2 diabetes mellitus. 47th European Association for the Study of Diabetes (EASD) Annual Meeting; 12-16 September 2011; Lisbon, Portugal; Poster 846
    • 47th European Association for the Study of Diabetes (EASD
    • Sasaki, T.1    Seino, Y.2    Fukatsu, A.3
  • 20
    • 84910672428 scopus 로고    scopus 로고
    • Effects of gender and age on the pharmacokinetics and pharmacodynamics of luseogliflozin (TS-071), a selective SGLT2 inhibitor
    • 8-12 June 2012; Philadelphia, PA, USA; Poster 1069-p
    • Sasaki M.,Seino Y.,Samukawa Y, et al. Effects of gender and age on the pharmacokinetics and pharmacodynamics of luseogliflozin (TS-071), a selective SGLT2 inhibitor 72nd Scientific Sessions of the American Diabetes Association 8-12 June 2012; Philadelphia, PA, USA; Poster 1069-p
    • 72nd Scientific Sessions of the American Diabetes Association
    • Sasaki, M.1    Seino, Y.2    Samukawa, Y.3
  • 21
    • 84910620044 scopus 로고    scopus 로고
    • Luseogliflozin (TS-071), a selective SGLT2 inhibitor, improves glycemic control in Japanese type 2 diabetic subjects with renal impairment
    • Annual Meeting; 1-5 October 2012; Berlin, Germany; Poster 741
    • Haneda M., Seino Y., Sasaki T., et al. Luseogliflozin (TS-071), a selective SGLT2 inhibitor, improves glycemic control in Japanese type 2 diabetic subjects with renal impairment 48th European Association for the Study of Diabetes (EASD Annual Meeting; 1-5 October 2012; Berlin, Germany; Poster 741
    • 48th European Association for the Study of Diabetes (EASD
    • Haneda, M.1    Seino, Y.2    Sasaki, T.3
  • 22
    • 84903557735 scopus 로고    scopus 로고
    • Efficacy and safety of luseogliflozin as monotherapy in Japanese patients with type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled, phase 3 study
    • Seino Y, Sasaki T, Fukatsu A, et al. Efficacy and safety of luseogliflozin as monotherapy in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled, phase 3 study. Curr Med Res Opin 2014;30: 1245-55
    • (2014) Curr Med Res Opin , vol.30 , pp. 1245-1255
    • Seino, Y.1    Sasaki, T.2    Fukatsu, A.3
  • 25
    • 84883810898 scopus 로고    scopus 로고
    • Urinary tract infections in patients with diabetes treated with dapagliflozin
    • Johnsson KM, Ptaszynska A, Schmitz B, et al. Urinary tract infections in patients with diabetes treated with dapagliflozin. J Diabetes Complications 2013;27: 473-8
    • (2013) J Diabetes Complications , vol.27 , pp. 473-478
    • Johnsson, K.M.1    Ptaszynska, A.2    Schmitz, B.3
  • 26
    • 84883799810 scopus 로고    scopus 로고
    • Vulvovaginitis and balanitis in patients with diabetes treated with dapagliflozin
    • Johnsson KM, Ptaszynska A, Schmitz B, et al. Vulvovaginitis and balanitis in patients with diabetes treated with dapagliflozin. J Diabetes Complications 2013;27: 479-84
    • (2013) J Diabetes Complications , vol.27 , pp. 479-484
    • Johnsson, K.M.1    Ptaszynska, A.2    Schmitz, B.3
  • 28
    • 84910596883 scopus 로고    scopus 로고
    • Ono Pharmaceutical Co., Ltd., Osaka, AstraZeneca, London. Available from Last accessed 12 August 2014]
    • Forxiga-receives regulatory approval in Japan for the treatment of type 2 diabetes [media release]. Ono Pharmaceutical Co., Ltd., Osaka, AstraZeneca, London. Available from: http://www.astrazeneca.com/Media/Pressreleases/Article/20140324-forxiga-japanapproval [Last accessed 12 August 2014]
    • Forxiga-receives Regulatory Approval in Japan for the Treatment of Type 2 Diabetes [Media Release
  • 29
    • 84902296808 scopus 로고    scopus 로고
    • Tofogliflozin: First global approval
    • Poole RM, Prossler JE. Tofogliflozin: first global approval. Drugs 2014;74: 939-44
    • (2014) Drugs , vol.74 , pp. 939-944
    • Poole, R.M.1    Prossler, J.E.2
  • 30
    • 84910594693 scopus 로고    scopus 로고
    • Mitsubishi Tanabe Pharma Corporation, Osaka; Daiichi Sankyo Co., Ltd., Tokyo. Available from [Last accessed 25 August 2014]
    • Marketing and manufacturing approval in Japan received for Canaglu-Tablets 100 mg [media release]. Mitsubishi Tanabe Pharma Corporation, Osaka; Daiichi Sankyo Co., Ltd., Tokyo. Available from: http://www.mt-pharma. co.jp/e/release/nr/2014/pdf/e-MTPC140704.pdf [Last accessed 25 August 2014]
    • Marketing and Manufacturing Approval in Japan Received for Canaglu-Tablets 100 Mg [Media Release
  • 31
    • 84902242668 scopus 로고    scopus 로고
    • Dose-finding study of luseogliflozin in japanese patients with type 2 diabetes mellitus: A 12-week, randomized, doubleblind, placebo-controlled, phase ii study
    • Seino Y, Sasaki T, Fukatsu A, et al. Dose-finding study of luseogliflozin in Japanese patients with type 2 diabetes mellitus: a 12-week, randomized, doubleblind, placebo-controlled, phase II study. Curr Med Res Opin 2014;30: 1231-44
    • (2014) Curr Med Res Opin , vol.30 , pp. 1231-1244
    • Seino, Y.1    Sasaki, T.2    Fukatsu, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.