Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model

Interdisciplinary Toxicology

Volumn 7, Issue 2, 2014, Pages 73-84

  Luettich, Karsta ^a   Xiang, Yang ^a   Iskandar, Anita ^a   Sewer, Alain ^a   Martin, Florian ^a   Talikka, Marja ^a   Vanscheeuwijck, Patrick ^a,b   Berges, An ^b   Veljkovic, Emilija ^a   Gonzalez Suarez, Ignacio ^a   Schlage, Walter ^a   Hoeng, Julia ^a   Peitsch, Manuel ^a  

^a PHILIP MORRIS PRODUCTS S A   (Switzerland)

^b Philip Morris Research Laboratories Bvba   (Belgium)

Author keywords

A J mouse; cigarette smoke exposure; gene expression; lung tumorigenesis; microRNA (miRNA) expression

Indexed keywords

CIGARETTE SMOKE; GLYCOSAMINOGLYCAN; MESSENGER RNA; MICRORNA; SPHINGOLIPID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE INTERACTION; GLYCOSAMINOGLYCAN METABOLISM; HISTOPATHOLOGY; HUMORAL IMMUNITY; IMMUNOSURVEILLANCE; LUNG ADENOMA; LUNG CARCINOMA; LUNG PARENCHYMA; LUNG TUMOR; MALE; MOUSE; NODULAR HYPERPLASIA; NONHUMAN; SMOKING; SPHINGOLIPID METABOLISM; SUPPORT VECTOR MACHINE; TUMOR GROWTH;

EID: 84910677974     PISSN: 13376853     EISSN: 13379569     Source Type: Journal    
DOI: 10.2478/intox-2014-0010     Document Type: Article

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