Lung inflammatory effects, tumorigenesis, and emphysema development in a long-term inhalation study with cigarette mainstream smoke in mice

Toxicological Sciences

Volumn 131, Issue 2, 2013, Pages 596-611

  Stinn, Walter ^a   Buettner, Ansgar ^a   Weiler, Horst ^a   Friedrichs, Baerbel ^a   Luetjen, Sonja ^a   van Overveld, Frans ^b   Meurrens, Kris ^b   Janssens, Kris ^a   Gebel, Stephan ^a   Stabbert, Regina ^c   Haussmann, Hans Juergen ^d  

^a Philip Morris Research Laboratories GmbH   (Germany)

^b Philip Morris Research Laboratories Bvba   (Belgium)

^c PHILIP MORRIS PRODUCTS S A   (Switzerland)

^d Toxicology Consultant ^*  (Germany)

Author keywords

A J mice; Cigarette mainstream smoke; Inhalation; Lung inflammation; Lung tumorigenesis; Pulmonary emphysema

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC DISEASE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMPHYSEMA; EXPOSURE; HISTOPATHOLOGY; INHALATION; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL CARCINOMA; LUNG CARCINOGENESIS; MALE; MORPHOMETRICS; MOUSE; NODULAR HYPERPLASIA; NONHUMAN; PARTICULATE MATTER; PNEUMONIA; SMOKING;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; EMPHYSEMA; INHALATION EXPOSURE; LUNG; MALE; MICE; PNEUMONIA; SMOKE; TOBACCO;

EID: 84873810977     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs312     Document Type: Article

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