메뉴 건너뛰기




Volumn 9, Issue 11, 2014, Pages

Rnd3 regulates lung cancer cell proliferation through Notch signaling

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; NOTCH INTRACELLULAR DOMAIN PROTEIN; NOTCH RECEPTOR; PROTEASOME; PROTEIN RND3; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HES1 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; RND3 PROTEIN, HUMAN;

EID: 84910671550     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0111897     Document Type: Article
Times cited : (30)

References (36)
  • 1
    • 58349091690 scopus 로고    scopus 로고
    • Gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity
    • Meng RD, Shelton CC, Li YM, Qin LX, Notterman D, et al. (2009) gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity. Cancer Res 69:573-582.
    • (2009) Cancer Res , vol.69 , pp. 573-582
    • Meng, R.D.1    Shelton, C.C.2    Li, Y.M.3    Qin, L.X.4    Notterman, D.5
  • 2
    • 34249936877 scopus 로고    scopus 로고
    • Notch signaling inhibits growth of the human lung adenocarcinoma cell line A549
    • Zheng Q, Qin H, Zhang H, Li J, Hou L, et al. (2007) Notch signaling inhibits growth of the human lung adenocarcinoma cell line A549. Oncology reports 17:847-852.
    • (2007) Oncology Reports , vol.17 , pp. 847-852
    • Zheng, Q.1    Qin, H.2    Zhang, H.3    Li, J.4    Hou, L.5
  • 3
    • 34548599785 scopus 로고    scopus 로고
    • Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung
    • Chen Y, De Marco MA, Graziani I, Gazdar AF, Strack PR, et al. (2007) Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung. Cancer Res 67:7954-7959.
    • (2007) Cancer Res , vol.67 , pp. 7954-7959
    • Chen, Y.1    De Marco, M.A.2    Graziani, I.3    Gazdar, A.F.4    Strack, P.R.5
  • 6
    • 0036232358 scopus 로고    scopus 로고
    • Socius is a novel Rnd GTPaseinteracting protein involved in disassembly of actin stress fibers
    • Katoh H, Harada A, Mori K, Negishi M (2002) Socius is a novel Rnd GTPaseinteracting protein involved in disassembly of actin stress fibers. Molecular and cellular biology 22:2952-2964.
    • (2002) Molecular and Cellular Biology , vol.22 , pp. 2952-2964
    • Katoh, H.1    Harada, A.2    Mori, K.3    Negishi, M.4
  • 8
    • 84876112231 scopus 로고    scopus 로고
    • Suppression of RND3 activity by AES downregulation promotes cancer cell proliferation and invasion
    • Xia H, Li M, Chen L, Leng W, Yuan D, et al. (2013) Suppression of RND3 activity by AES downregulation promotes cancer cell proliferation and invasion. Int J Mol Med 31:1081-1086.
    • (2013) Int J Mol Med , vol.31 , pp. 1081-1086
    • Xia, H.1    Li, M.2    Chen, L.3    Leng, W.4    Yuan, D.5
  • 9
    • 33845420563 scopus 로고    scopus 로고
    • RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress
    • Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, der CJ, et al. (2006) RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress. Curr Biol 16:2466-2472.
    • (2006) Curr Biol , vol.16 , pp. 2466-2472
    • Ongusaha, P.P.1    Kim, H.G.2    Boswell, S.A.3    Ridley, A.J.4    Der, C.J.5
  • 10
    • 84872138430 scopus 로고    scopus 로고
    • RhoE is frequently down-regulated in hepatocellular carcinoma (HCC) and suppresses HCC invasion through antagonizing the Rho/Rho-kinase/myosin phosphatase target pathway
    • Ma W, Wong CC, Tung EK, Wong CM, Ng IO (2013) RhoE is frequently down-regulated in hepatocellular carcinoma (HCC) and suppresses HCC invasion through antagonizing the Rho/Rho-kinase/myosin phosphatase target pathway. Hepatology 57:152-161.
    • (2013) Hepatology , vol.57 , pp. 152-161
    • Ma, W.1    Wong, C.C.2    Tung, E.K.3    Wong, C.M.4    Ng, I.O.5
  • 11
    • 84868099035 scopus 로고    scopus 로고
    • RhoE functions as a tumor suppressor in esophageal squamous cell carcinoma and modulates the PTEN/PI3 K/Akt signaling pathway
    • Zhao H, Yang J, Fan T, Li S, Ren X (2012) RhoE functions as a tumor suppressor in esophageal squamous cell carcinoma and modulates the PTEN/PI3 K/Akt signaling pathway. Tumour Biol 33:1363-1374.
    • (2012) Tumour Biol , vol.33 , pp. 1363-1374
    • Zhao, H.1    Yang, J.2    Fan, T.3    Li, S.4    Ren, X.5
  • 12
    • 78649771814 scopus 로고    scopus 로고
    • Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells
    • Belgiovine C, Frapolli R, Bonezzi K, Chiodi I, Favero F, et al. (2010) Reduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cells. PLoS One 5:e14154.
    • (2010) PLoS One , vol.5 , pp. e14154
    • Belgiovine, C.1    Frapolli, R.2    Bonezzi, K.3    Chiodi, I.4    Favero, F.5
  • 13
    • 4444355324 scopus 로고    scopus 로고
    • RhoE inhibits cell cycle progression and Ras-induced transformation
    • Villalonga P, Guasch RM, Riento K, Ridley AJ (2004) RhoE inhibits cell cycle progression and Ras-induced transformation. Mol Cell Biol 24:7829-7840.
    • (2004) Mol Cell Biol , vol.24 , pp. 7829-7840
    • Villalonga, P.1    Guasch, R.M.2    Riento, K.3    Ridley, A.J.4
  • 14
    • 38849185196 scopus 로고    scopus 로고
    • PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE
    • Pinner S, Sahai E (2008) PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE. Nature cell biology 10:127-137.
    • (2008) Nature Cell Biology , vol.10 , pp. 127-137
    • Pinner, S.1    Sahai, E.2
  • 15
    • 0035838950 scopus 로고    scopus 로고
    • Pharmacological profile of hydroxy fasudil as a selective rho kinase inhibitor on ischemic brain damage
    • Satoh S, Utsunomiya T, Tsurui K, Kobayashi T, Ikegaki I, et al. (2001) Pharmacological profile of hydroxy fasudil as a selective rho kinase inhibitor on ischemic brain damage. Life Sci 69:1441-1453.
    • (2001) Life Sci , vol.69 , pp. 1441-1453
    • Satoh, S.1    Utsunomiya, T.2    Tsurui, K.3    Kobayashi, T.4    Ikegaki, I.5
  • 16
    • 0037007054 scopus 로고    scopus 로고
    • Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina
    • Masumoto A, Mohri M, Shimokawa H, Urakami L, Usui M, et al. (2002) Suppression of coronary artery spasm by the Rho-kinase inhibitor fasudil in patients with vasospastic angina. Circulation 105:1545-1547.
    • (2002) Circulation , vol.105 , pp. 1545-1547
    • Masumoto, A.1    Mohri, M.2    Shimokawa, H.3    Urakami, L.4    Usui, M.5
  • 17
    • 18044392754 scopus 로고    scopus 로고
    • Determination of guinea-pig cortical gamma-secretase activity ex vivo following the systemic administration of a gamma-secretase inhibitor
    • Grimwood S, Hogg J, Jay MT, Lad AM, Lee V, et al. (2005) Determination of guinea-pig cortical gamma-secretase activity ex vivo following the systemic administration of a gamma-secretase inhibitor. Neuropharmacology 48:1002-1011.
    • (2005) Neuropharmacology , vol.48 , pp. 1002-1011
    • Grimwood, S.1    Hogg, J.2    Jay, M.T.3    Lad, A.M.4    Lee, V.5
  • 18
    • 84894597284 scopus 로고    scopus 로고
    • Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy
    • Liu J, Mao Z, Huang J, Xie S, Liu T (2014) Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy. Biochem Biophys Res Commun 444:670-675.
    • (2014) Biochem Biophys Res Commun , vol.444 , pp. 670-675
    • Liu, J.1    Mao, Z.2    Huang, J.3    Xie, S.4    Liu, T.5
  • 19
    • 84892180066 scopus 로고    scopus 로고
    • Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control
    • Marcelo KL, Sills TM, Coskun S, Vasavada H, Sanglikar S, et al. (2013) Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control. Dev Cell 27:504-515.
    • (2013) Dev Cell , vol.27 , pp. 504-515
    • Marcelo, K.L.1    Sills, T.M.2    Coskun, S.3    Vasavada, H.4    Sanglikar, S.5
  • 20
    • 84901016625 scopus 로고    scopus 로고
    • Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer
    • Dai Y, Wilson G, Huang B, Peng M, Teng G, et al. (2014) Silencing of Jagged1 inhibits cell growth and invasion in colorectal cancer. Cell death & disease 5:e1170.
    • (2014) Cell Death & Disease , vol.5 , pp. e1170
    • Dai, Y.1    Wilson, G.2    Huang, B.3    Peng, M.4    Teng, G.5
  • 21
    • 84877842070 scopus 로고    scopus 로고
    • Genetic deletion of Rnd3 results in aqueductal stenosis leading to hydrocephalus through up-regulation of Notch signaling
    • Lin X, Liu B, Yang X, Yue X, Diao L, et al. (2013) Genetic deletion of Rnd3 results in aqueductal stenosis leading to hydrocephalus through up-regulation of Notch signaling. Proc Natl Acad Sci U S A 110:8236-8241.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 8236-8241
    • Lin, X.1    Liu, B.2    Yang, X.3    Yue, X.4    Diao, L.5
  • 22
    • 0037663379 scopus 로고    scopus 로고
    • Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain
    • McGill MA, McGlade CJ (2003) Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J Biol Chem 278:23196-23203.
    • (2003) J Biol Chem , vol.278 , pp. 23196-23203
    • McGill, M.A.1    McGlade, C.J.2
  • 23
    • 84861563951 scopus 로고    scopus 로고
    • Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion
    • Grise F, Sena S, Bidaud-Meynard A, Baud J, Hiriart JB, et al. (2012) Rnd3/RhoE Is down-regulated in hepatocellular carcinoma and controls cellular invasion. Hepatology 55:1766-1775.
    • (2012) Hepatology , vol.55 , pp. 1766-1775
    • Grise, F.1    Sena, S.2    Bidaud-Meynard, A.3    Baud, J.4    Hiriart, J.B.5
  • 25
    • 0034672412 scopus 로고    scopus 로고
    • Growth-suppressive effect of non-steroidal anti-inflammatory drugs on 11 colon-cancer cell lines and fluorescence differential display of genes whose expression is influenced by sulindac
    • Akashi H, Han HJ, Iizaka M, Nakamura Y (2000) Growth-suppressive effect of non-steroidal anti-inflammatory drugs on 11 colon-cancer cell lines and fluorescence differential display of genes whose expression is influenced by sulindac. Int J Cancer 88:873-880.
    • (2000) Int J Cancer , vol.88 , pp. 873-880
    • Akashi, H.1    Han, H.J.2    Iizaka, M.3    Nakamura, Y.4
  • 26
    • 0030598834 scopus 로고    scopus 로고
    • Simultaneous suppression of progression marker genes in the highly malignant human melanoma cell line BLM after transfection with the adenovirus-5 E1A gene
    • van Groningen JJ, Cornelissen IM, van Muijen GN, Bloemers HP, Swart GW (1996) Simultaneous suppression of progression marker genes in the highly malignant human melanoma cell line BLM after transfection with the adenovirus-5 E1A gene. Biochem Biophys Res Commun 225:808-816.
    • (1996) Biochem Biophys Res Commun , vol.225 , pp. 808-816
    • Van Groningen, J.J.1    Cornelissen, I.M.2    Van Muijen, G.N.3    Bloemers, H.P.4    Swart, G.W.5
  • 27
    • 34548547220 scopus 로고    scopus 로고
    • Overexpression of RhoE has a prognostic value in non-small cell lung cancer
    • Zhang C, Zhou F, Li N, Shi S, Feng X, et al. (2007) Overexpression of RhoE has a prognostic value in non-small cell lung cancer. Annals of surgical oncology 14:2628-2635.
    • (2007) Annals of Surgical Oncology , vol.14 , pp. 2628-2635
    • Zhang, C.1    Zhou, F.2    Li, N.3    Shi, S.4    Feng, X.5
  • 28
    • 34548225160 scopus 로고    scopus 로고
    • Overexpression of RhoE in Non-small Cell Lung Cancer (NSCLC) is associated with smoking and correlates with DNA copy number changes
    • Cuiyan Z, Jie H, Fang Z, Kezhi Z, Junting W, et al. (2007) Overexpression of RhoE in Non-small Cell Lung Cancer (NSCLC) is associated with smoking and correlates with DNA copy number changes. Cancer Biol Ther 6:335-342.
    • (2007) Cancer Biol Ther , vol.6 , pp. 335-342
    • Cuiyan, Z.1    Jie, H.2    Fang, Z.3    Kezhi, Z.4    Junting, W.5
  • 29
    • 23944518729 scopus 로고    scopus 로고
    • Small G-protein RhoE is underexpressed in prostate cancer and induces cell cycle arrest and apoptosis
    • Bektic J, Pfeil K, Berger AP, Ramoner R, Pelzer A, et al. (2005) Small G-protein RhoE is underexpressed in prostate cancer and induces cell cycle arrest and apoptosis. Prostate 64:332-340.
    • (2005) Prostate , vol.64 , pp. 332-340
    • Bektic, J.1    Pfeil, K.2    Berger, A.P.3    Ramoner, R.4    Pelzer, A.5
  • 30
    • 79952763999 scopus 로고    scopus 로고
    • Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling
    • Pacary E, Heng J, Azzarelli R, Riou P, Castro D, et al. (2011) Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron 69:1069-1084.
    • (2011) Neuron , vol.69 , pp. 1069-1084
    • Pacary, E.1    Heng, J.2    Azzarelli, R.3    Riou, P.4    Castro, D.5
  • 31
    • 79954564683 scopus 로고    scopus 로고
    • Rnd-ing up RhoA activity to link neurogenesis with steps in neuronal migration
    • Li J, Anton ES (2011) Rnd-ing up RhoA activity to link neurogenesis with steps in neuronal migration. Dev Cell 20:409-410.
    • (2011) Dev Cell , vol.20 , pp. 409-410
    • Li, J.1    Anton, E.S.2
  • 32
    • 79956017928 scopus 로고    scopus 로고
    • FOXD3 regulates migration properties and Rnd3 expression in melanoma cells
    • Katiyar P, Aplin AE (2011) FOXD3 Regulates Migration Properties and Rnd3 Expression in Melanoma Cells. Molecular cancer research: MCR 9:545-552.
    • (2011) Molecular Cancer Research: MCR , vol.9 , pp. 545-552
    • Katiyar, P.1    Aplin, A.E.2
  • 34
    • 84897411810 scopus 로고    scopus 로고
    • Small GTPase RhoE/Rnd3 Is a critical regulator of Notch1 signaling
    • Zhu Z, Todorova K, Lee KK, Wang J, Kwon E, et al. (2014) Small GTPase RhoE/Rnd3 Is a Critical Regulator of Notch1 Signaling. Cancer Res 74:2082-2093.
    • (2014) Cancer Res , vol.74 , pp. 2082-2093
    • Zhu, Z.1    Todorova, K.2    Lee, K.K.3    Wang, J.4    Kwon, E.5
  • 35
    • 84871735961 scopus 로고    scopus 로고
    • RhoE is associated with relapse and prognosis of patients with colorectal cancer
    • Zhou J, Yang J, Li K, Mo P, Feng B, et al. (2013) RhoE is associated with relapse and prognosis of patients with colorectal cancer. Annals of surgical oncology 20:175-182.
    • (2013) Annals of Surgical Oncology , vol.20 , pp. 175-182
    • Zhou, J.1    Yang, J.2    Li, K.3    Mo, P.4    Feng, B.5
  • 36
    • 84859910902 scopus 로고    scopus 로고
    • Down-regulation of RhoE is associated with progression and poor prognosis in hepatocellular carcinoma
    • Luo H, Dong Z, Zou J, Zeng Q, Wu D, et al. (2012) Down-regulation of RhoE is associated with progression and poor prognosis in hepatocellular carcinoma. J Surg Oncol 105:699-704.
    • (2012) J Surg Oncol , vol.105 , pp. 699-704
    • Luo, H.1    Dong, Z.2    Zou, J.3    Zeng, Q.4    Wu, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.