Perillaldehyde attenuates cerebral ischemia-reperfusion injury-triggered overexpression of inflammatory cytokines via modulating Akt/JNK pathway in the rat brain cortex

Biochemical and Biophysical Research Communications

Volumn 454, Issue 1, 2014, Pages 65-70

  Xu, Lixing ^a   Li, Yuebi ^a   Fu, Qiang ^a   Ma, Shiping ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Akt; Apoptotic cell death; Inflammatory cytokines; Ischaemia reperfusion injury; JNK; Perillaldehyde

Indexed keywords

CASPASE 3; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PERILLALDEHYDE; PROTEIN BAX; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; BAX PROTEIN, RAT; CASP3 PROTEIN, RAT; CYTOKINE; TERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MEGADOSE; ENZYME PHOSPHORYLATION; EXPERIMENTAL NEUROLOGIC DISEASE; GENE OVEREXPRESSION; LOW DRUG DOSE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHAM PROCEDURE; WESTERN BLOTTING; ANIMAL; BLOOD; BRAIN INJURIES; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BRAIN INJURIES; BRAIN ISCHEMIA; CASPASE 3; CYTOKINES; DISEASE MODELS, ANIMAL; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MAP KINASE SIGNALING SYSTEM; MONOTERPENES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84910662662     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.10.025     Document Type: Article

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