메뉴 건너뛰기




Volumn 209, Issue , 2014, Pages 131-146

Mechanism of sympathetic activation and blood pressure elevation in humans and animals following acute intermittent hypoxia

Author keywords

Autonomic nervous system; Hypertension; Long term facilitation; Reflexes; Serotonin; Sleep apnea; Sympathetic nervous system; Sympathoexcitation

Indexed keywords

ACUTE INTERMITTENT HYPOXIA; ARTICLE; BLOOD PRESSURE; BRAIN CIRCULATION; BRAIN REGION; CAROTID BODY CHEMORECEPTOR; CHEMORECEPTOR REFLEX; HUMAN; HYPERTENSION; INTERMITTENT HYPOXIA; MUSCLE SYMPATHETIC NERVE ACTIVITY; NERVE CELL PLASTICITY; NONHUMAN; PARAVENTRICULAR NUCLEUS; PREGANGLIONIC NERVE CELL; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; ROSTRAL VENTROLATERAL MEDULLA; ADRENERGIC SYSTEM; ANIMAL; ANOXIA; COMPLICATION; PATHOPHYSIOLOGY; SLEEP DISORDERED BREATHING;

EID: 84910647922     PISSN: 00796123     EISSN: 18757855     Source Type: Book Series    
DOI: 10.1016/B978-0-444-63274-6.00007-2     Document Type: Chapter
Times cited : (26)

References (85)
  • 1
    • 0000657016 scopus 로고
    • Discharges in mammalian sympathetic nerves
    • Adrian E.D., Bronk D.W., Philips G. Discharges in mammalian sympathetic nerves. J. Physiol. 1932, 74:115-133.
    • (1932) J. Physiol. , vol.74 , pp. 115-133
    • Adrian, E.D.1    Bronk, D.W.2    Philips, G.3
  • 2
    • 79954424275 scopus 로고    scopus 로고
    • Role of angiotensin in the rostral ventrolateral medulla in the development and maintenance of hypertension
    • Allen A.M. Role of angiotensin in the rostral ventrolateral medulla in the development and maintenance of hypertension. Curr. Opin. Pharmacol. 2011, 11:117-123.
    • (2011) Curr. Opin. Pharmacol. , vol.11 , pp. 117-123
    • Allen, A.M.1
  • 3
    • 0027970226 scopus 로고
    • Serotoninergic and nonserotoninergic neurons in the medullary raphe system have axon collateral projections to autonomic and somatic cell groups in the medulla and spinal cord
    • Allen G.V., Cechetto D.F. Serotoninergic and nonserotoninergic neurons in the medullary raphe system have axon collateral projections to autonomic and somatic cell groups in the medulla and spinal cord. J. Comp. Neurol. 1994, 350:357-366.
    • (1994) J. Comp. Neurol. , vol.350 , pp. 357-366
    • Allen, G.V.1    Cechetto, D.F.2
  • 4
    • 0037008391 scopus 로고    scopus 로고
    • Serotonergic projections to the rostroventrolateral medulla from midbrain and raphe nuclei
    • Bago M., Marson L., Dean C. Serotonergic projections to the rostroventrolateral medulla from midbrain and raphe nuclei. Brain Res. 2002, 945:249-258.
    • (2002) Brain Res. , vol.945 , pp. 249-258
    • Bago, M.1    Marson, L.2    Dean, C.3
  • 5
    • 0030738644 scopus 로고    scopus 로고
    • Blood pressure response to chronic episodic hypoxia: role of the sympathetic nervous system
    • Bao G., Metreveli N., Li R., Taylor A., Fletcher E.C. Blood pressure response to chronic episodic hypoxia: role of the sympathetic nervous system. J. Appl. Physiol. 1997, 83:95-101.
    • (1997) J. Appl. Physiol. , vol.83 , pp. 95-101
    • Bao, G.1    Metreveli, N.2    Li, R.3    Taylor, A.4    Fletcher, E.C.5
  • 6
    • 84859567338 scopus 로고    scopus 로고
    • Recurrent laryngeal nerve activity exhibits a 5-HT-mediated long-term facilitation and enhanced response to hypoxia following acute intermittent hypoxia in rat
    • Bautista T.G., Xing T., Fong A.Y., Pilowsky P.M. Recurrent laryngeal nerve activity exhibits a 5-HT-mediated long-term facilitation and enhanced response to hypoxia following acute intermittent hypoxia in rat. J. Appl. Physiol. 2012, 112:1144-1156.
    • (2012) J. Appl. Physiol. , vol.112 , pp. 1144-1156
    • Bautista, T.G.1    Xing, T.2    Fong, A.Y.3    Pilowsky, P.M.4
  • 7
    • 0037216240 scopus 로고    scopus 로고
    • Intermittent hypoxia induces phrenic long-term facilitation in carotid-denervated rats
    • Bavis R.W., Mitchell G.S. Intermittent hypoxia induces phrenic long-term facilitation in carotid-denervated rats. J. Appl. Physiol. 2003, 94:399-409.
    • (2003) J. Appl. Physiol. , vol.94 , pp. 399-409
    • Bavis, R.W.1    Mitchell, G.S.2
  • 10
    • 3242660893 scopus 로고    scopus 로고
    • Effects of simulated obstructive sleep apnoea on the human carotid baroreceptor-vascular resistance reflex
    • Cooper V.L., Bowker C.M., Pearson S.B., Elliott M.W., Hainsworth R. Effects of simulated obstructive sleep apnoea on the human carotid baroreceptor-vascular resistance reflex. J. Physiol. 2004, 557:1055-1065.
    • (2004) J. Physiol. , vol.557 , pp. 1055-1065
    • Cooper, V.L.1    Bowker, C.M.2    Pearson, S.B.3    Elliott, M.W.4    Hainsworth, R.5
  • 11
    • 33847732727 scopus 로고    scopus 로고
    • Daytime variability of baroreflex function in patients with obstructive sleep apnoea: implications for hypertension
    • Cooper V.L., Elliott M.W., Pearson S.B., Taylor C.M., Mohammed M.M., Hainsworth R. Daytime variability of baroreflex function in patients with obstructive sleep apnoea: implications for hypertension. Exp. Physiol. 2007, 92:391-398.
    • (2007) Exp. Physiol. , vol.92 , pp. 391-398
    • Cooper, V.L.1    Elliott, M.W.2    Pearson, S.B.3    Taylor, C.M.4    Mohammed, M.M.5    Hainsworth, R.6
  • 12
    • 14944348969 scopus 로고    scopus 로고
    • A role for the paraventricular nucleus of the hypothalamus in the autonomic control of heart and kidney
    • Coote J.H. A role for the paraventricular nucleus of the hypothalamus in the autonomic control of heart and kidney. Exp. Physiol. 2005, 90:169-173.
    • (2005) Exp. Physiol. , vol.90 , pp. 169-173
    • Coote, J.H.1
  • 13
    • 55949102247 scopus 로고    scopus 로고
    • Intermittent activation of peripheral chemoreceptors in awake rats induces Fos expression in rostral ventrolateral medulla-projecting neurons in the paraventricular nucleus of the hypothalamus
    • Cruz J.C., Bonagamba L.G., Machado B.H., Biancardi V.C., Stern J.E. Intermittent activation of peripheral chemoreceptors in awake rats induces Fos expression in rostral ventrolateral medulla-projecting neurons in the paraventricular nucleus of the hypothalamus. Neuroscience 2008, 157:463-472.
    • (2008) Neuroscience , vol.157 , pp. 463-472
    • Cruz, J.C.1    Bonagamba, L.G.2    Machado, B.H.3    Biancardi, V.C.4    Stern, J.E.5
  • 14
    • 19344373310 scopus 로고    scopus 로고
    • Time-dependent modulation of carotid body afferent activity during and after intermittent hypoxia
    • Cummings K.J., Wilson R.J. Time-dependent modulation of carotid body afferent activity during and after intermittent hypoxia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005, 288:R1571-R1580.
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.288
    • Cummings, K.J.1    Wilson, R.J.2
  • 15
    • 0942287686 scopus 로고    scopus 로고
    • Hypoxia-mediated prolonged elevation of sympathetic nerve activity after periods of intermittent hypoxic apnea
    • Cutler M.J., Muenter Swift N., Keller D.M., Wasmund W.L., Smith M.L. Hypoxia-mediated prolonged elevation of sympathetic nerve activity after periods of intermittent hypoxic apnea. J. Appl. Physiol. 2004, 96:754-761.
    • (2004) J. Appl. Physiol. , vol.96 , pp. 754-761
    • Cutler, M.J.1    Muenter Swift, N.2    Keller, D.M.3    Wasmund, W.L.4    Smith, M.L.5
  • 17
    • 78651104672 scopus 로고    scopus 로고
    • Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea
    • da Silva A.Q., Fontes M.A., Kanagy N.L. Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea. Brain Res. 2011, 1368:231-238.
    • (2011) Brain Res. , vol.1368 , pp. 231-238
    • da Silva, A.Q.1    Fontes, M.A.2    Kanagy, N.L.3
  • 19
    • 33846235510 scopus 로고    scopus 로고
    • Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat
    • Dick T.E., Hsieh Y.H., Wang N., Prabhakar N. Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat. Exp. Physiol. 2007, 92:87-97.
    • (2007) Exp. Physiol. , vol.92 , pp. 87-97
    • Dick, T.E.1    Hsieh, Y.H.2    Wang, N.3    Prabhakar, N.4
  • 20
    • 0026656461 scopus 로고
    • Carotid chemoreceptors, systemic blood pressure, and chronic episodic hypoxia mimicking sleep apnea
    • Fletcher E.C., Lesske J., Behm R., Miller Iii C.C., Stauss H., Unger T. Carotid chemoreceptors, systemic blood pressure, and chronic episodic hypoxia mimicking sleep apnea. J. Appl. Physiol. 1992, 72:1978-1984.
    • (1992) J. Appl. Physiol. , vol.72 , pp. 1978-1984
    • Fletcher, E.C.1    Lesske, J.2    Behm, R.3    Miller Iii, C.C.4    Stauss, H.5    Unger, T.6
  • 21
    • 0032870245 scopus 로고    scopus 로고
    • Renin activity and blood pressure in response to chronic episodic hypoxia
    • Fletcher E.C., Bao G., Li R. Renin activity and blood pressure in response to chronic episodic hypoxia. Hypertension 1999, 34:309-314.
    • (1999) Hypertension , vol.34 , pp. 309-314
    • Fletcher, E.C.1    Bao, G.2    Li, R.3
  • 22
    • 0036090004 scopus 로고    scopus 로고
    • Blood pressure response to chronic episodic hypoxia: the renin-angiotensin system
    • Fletcher E.C., Orolinova N., Bader M. Blood pressure response to chronic episodic hypoxia: the renin-angiotensin system. J. Appl. Physiol. 2002, 92:627-633.
    • (2002) J. Appl. Physiol. , vol.92 , pp. 627-633
    • Fletcher, E.C.1    Orolinova, N.2    Bader, M.3
  • 23
    • 77955983313 scopus 로고    scopus 로고
    • Intermittent hypoxia increases arterial blood pressure in humans through a renin-angiotensin system-dependent mechanism
    • Foster G.E., Hanly P.J., Ahmed S.B., Beaudin A.E., Pialoux V., Poulin M.J. Intermittent hypoxia increases arterial blood pressure in humans through a renin-angiotensin system-dependent mechanism. Hypertension 2010, 56:369-377.
    • (2010) Hypertension , vol.56 , pp. 369-377
    • Foster, G.E.1    Hanly, P.J.2    Ahmed, S.B.3    Beaudin, A.E.4    Pialoux, V.5    Poulin, M.J.6
  • 24
    • 0032911907 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapnia
    • Greenberg H.E., Sica A., Batson D., Scharf S.M. Chronic intermittent hypoxia increases sympathetic responsiveness to hypoxia and hypercapnia. J. Appl. Physiol. 1999, 86:298-305.
    • (1999) J. Appl. Physiol. , vol.86 , pp. 298-305
    • Greenberg, H.E.1    Sica, A.2    Batson, D.3    Scharf, S.M.4
  • 25
    • 0033596516 scopus 로고    scopus 로고
    • Expression of c-fos in the rat brainstem after chronic intermittent hypoxia
    • Greenberg H.E., Sica A.L., Scharf S.M., Ruggiero D.A. Expression of c-fos in the rat brainstem after chronic intermittent hypoxia. Brain Res. 1999, 816:638-645.
    • (1999) Brain Res. , vol.816 , pp. 638-645
    • Greenberg, H.E.1    Sica, A.L.2    Scharf, S.M.3    Ruggiero, D.A.4
  • 27
    • 0033837666 scopus 로고    scopus 로고
    • Neural structures that mediate sympathoexcitation during hypoxia
    • Guyenet P.G. Neural structures that mediate sympathoexcitation during hypoxia. Respir. Physiol. 2000, 121:147-162.
    • (2000) Respir. Physiol. , vol.121 , pp. 147-162
    • Guyenet, P.G.1
  • 28
    • 33745712914 scopus 로고    scopus 로고
    • The sympathetic control of blood pressure
    • Guyenet P.G. The sympathetic control of blood pressure. Nat. Rev. Neurosci. 2006, 7:335-346.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 335-346
    • Guyenet, P.G.1
  • 29
    • 34248578612 scopus 로고    scopus 로고
    • Sympathetic chemoreflex responses in obstructive sleep apnea and effects of continuous positive airway pressure therapy
    • Imadojemu V.A., Mawji Z., Kunselman A., Gray K.S., Hogeman C.S., Leuenberger U.A. Sympathetic chemoreflex responses in obstructive sleep apnea and effects of continuous positive airway pressure therapy. Chest 2007, 131:1406-1413.
    • (2007) Chest , vol.131 , pp. 1406-1413
    • Imadojemu, V.A.1    Mawji, Z.2    Kunselman, A.3    Gray, K.S.4    Hogeman, C.S.5    Leuenberger, U.A.6
  • 30
    • 77954414533 scopus 로고    scopus 로고
    • Carotid sinus nerve stimulation, but not intermittent hypoxia, induces respiratory LTF in adult rats exposed to neonatal intermittent hypoxia
    • Julien C.A., Niane L., Kinkead R., Bairam A., Joseph V. Carotid sinus nerve stimulation, but not intermittent hypoxia, induces respiratory LTF in adult rats exposed to neonatal intermittent hypoxia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2010, 299:R192-R205.
    • (2010) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.299
    • Julien, C.A.1    Niane, L.2    Kinkead, R.3    Bairam, A.4    Joseph, V.5
  • 31
    • 84940277647 scopus 로고    scopus 로고
    • Exposure to acute intermittent hypoxia (IH) prolongs sympathoexcitatory and pressor responses evoked by NMDA in the hypothalamic paraventricular nucleus (PVN)
    • 899.10
    • Kandlikar S.S., Andrade M.A., Calderson A.S., Toney G.M. Exposure to acute intermittent hypoxia (IH) prolongs sympathoexcitatory and pressor responses evoked by NMDA in the hypothalamic paraventricular nucleus (PVN). FASEB J. 2012, 26:899.10.
    • (2012) FASEB J. , vol.26
    • Kandlikar, S.S.1    Andrade, M.A.2    Calderson, A.S.3    Toney, G.M.4
  • 32
    • 77949493287 scopus 로고    scopus 로고
    • Increased vasopressin transmission from the paraventricular nucleus to the rostral medulla augments cardiorespiratory outflow in chronic intermittent hypoxia-conditioned rats
    • Kc P., Balan K.V., Tjoe S.S., Martin R.J., Lamanna J.C., Haxhiu M.A., Dick T.E. Increased vasopressin transmission from the paraventricular nucleus to the rostral medulla augments cardiorespiratory outflow in chronic intermittent hypoxia-conditioned rats. J. Physiol. 2010, 588:725-740.
    • (2010) J. Physiol. , vol.588 , pp. 725-740
    • Kc, P.1    Balan, K.V.2    Tjoe, S.S.3    Martin, R.J.4    Lamanna, J.C.5    Haxhiu, M.A.6    Dick, T.E.7
  • 34
    • 0034032809 scopus 로고    scopus 로고
    • Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea
    • Kraiczi H., Hedner J., Peker Y., Grote L. Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea. Am. J. Respir. Crit. Care Med. 2000, 161:1423-1428.
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 1423-1428
    • Kraiczi, H.1    Hedner, J.2    Peker, Y.3    Grote, L.4
  • 35
    • 33744944517 scopus 로고    scopus 로고
    • Enhanced sympathetic outflow and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats
    • Lai C.J., Yang C.C.H., Hsu Y.Y., Lin Y.N., Kuo T.B.J. Enhanced sympathetic outflow and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats. J. Appl. Physiol. 2006, 100:1974-1982.
    • (2006) J. Appl. Physiol. , vol.100 , pp. 1974-1982
    • Lai, C.J.1    Yang, C.C.H.2    Hsu, Y.Y.3    Lin, Y.N.4    Kuo, T.B.J.5
  • 37
    • 34548410831 scopus 로고    scopus 로고
    • Short-term intermittent hypoxia enhances sympathetic responses to continuous hypoxia in humans
    • Leuenberger U.A., Hogeman C.S., Quraishi S., Linton-Frazier L., Gray K.S. Short-term intermittent hypoxia enhances sympathetic responses to continuous hypoxia in humans. J. Appl. Physiol. 2007, 103:835-842.
    • (2007) J. Appl. Physiol. , vol.103 , pp. 835-842
    • Leuenberger, U.A.1    Hogeman, C.S.2    Quraishi, S.3    Linton-Frazier, L.4    Gray, K.S.5
  • 38
    • 34547872784 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia impairs baroreflex control of heart rate but enhances heart rate responses to vagal efferent stimulation in anesthetized mice
    • Lin M., Liu R., Gozal D., Wead W.B., Chapleau M.W., Wurster R., Cheng Z. Chronic intermittent hypoxia impairs baroreflex control of heart rate but enhances heart rate responses to vagal efferent stimulation in anesthetized mice. Am. J. Physiol. Heart Circ. Physiol. 2007, 293:H997-H1006.
    • (2007) Am. J. Physiol. Heart Circ. Physiol. , vol.293
    • Lin, M.1    Liu, R.2    Gozal, D.3    Wead, W.B.4    Chapleau, M.W.5    Wurster, R.6    Cheng, Z.7
  • 40
    • 33751313602 scopus 로고    scopus 로고
    • Serotonin potentiates sympathetic responses evoked by spinal NMDA
    • Madden C.J., Morrison S.F. Serotonin potentiates sympathetic responses evoked by spinal NMDA. J. Physiol. 2006, 577:525-537.
    • (2006) J. Physiol. , vol.577 , pp. 525-537
    • Madden, C.J.1    Morrison, S.F.2
  • 41
    • 33846188463 scopus 로고    scopus 로고
    • Is there a link between intermittent hypoxia-induced respiratory plasticity and obstructive sleep apnoea?
    • Mahamed S., Mitchell G.S. Is there a link between intermittent hypoxia-induced respiratory plasticity and obstructive sleep apnoea?. Exp. Physiol. 2007, 92:27-37.
    • (2007) Exp. Physiol. , vol.92 , pp. 27-37
    • Mahamed, S.1    Mitchell, G.S.2
  • 42
    • 0025195336 scopus 로고
    • Stimulation of serotonin2 receptors in the ventrolateral medulla of the cat results in nonuniform increases in sympathetic outflow
    • Mandal A.K., Kellar K.J., Norman W.P., Gillis R.A. Stimulation of serotonin2 receptors in the ventrolateral medulla of the cat results in nonuniform increases in sympathetic outflow. Circ. Res. 1990, 67:1267-1280.
    • (1990) Circ. Res. , vol.67 , pp. 1267-1280
    • Mandal, A.K.1    Kellar, K.J.2    Norman, W.P.3    Gillis, R.A.4
  • 43
    • 77949571119 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia augments chemoreflex control of sympathetic activity: role of the angiotensin II type 1 receptor
    • Marcus N.J., Li Y.L., Bird C.E., Schultz H.D., Morgan B.J. Chronic intermittent hypoxia augments chemoreflex control of sympathetic activity: role of the angiotensin II type 1 receptor. Respir. Physiol. Neurobiol. 2010, 171:36-45.
    • (2010) Respir. Physiol. Neurobiol. , vol.171 , pp. 36-45
    • Marcus, N.J.1    Li, Y.L.2    Bird, C.E.3    Schultz, H.D.4    Morgan, B.J.5
  • 44
    • 79952455399 scopus 로고    scopus 로고
    • Experimental protocols and preparations to study respiratory long term facilitation
    • Mateika J.H., Sandhu K.S. Experimental protocols and preparations to study respiratory long term facilitation. Respir. Physiol. Neurobiol. 2011, 176:1-11.
    • (2011) Respir. Physiol. Neurobiol. , vol.176 , pp. 1-11
    • Mateika, J.H.1    Sandhu, K.S.2
  • 45
    • 0036891958 scopus 로고    scopus 로고
    • Effect of hypoxic episode number and severity on ventilatory long-term facilitation in awake rats
    • McGuire M., Zhang Y., White D.P., Ling L. Effect of hypoxic episode number and severity on ventilatory long-term facilitation in awake rats. J. Appl. Physiol. 2002, 93:2155-2161.
    • (2002) J. Appl. Physiol. , vol.93 , pp. 2155-2161
    • McGuire, M.1    Zhang, Y.2    White, D.P.3    Ling, L.4
  • 46
    • 0141455510 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia enhances ventilatory long-term facilitation in awake rats
    • McGuire M., Zhang Y., White D.P., Ling L. Chronic intermittent hypoxia enhances ventilatory long-term facilitation in awake rats. J. Appl. Physiol. 2003, 95:1499-1508.
    • (2003) J. Appl. Physiol. , vol.95 , pp. 1499-1508
    • McGuire, M.1    Zhang, Y.2    White, D.P.3    Ling, L.4
  • 47
    • 0030658764 scopus 로고    scopus 로고
    • Short-term potentiation of carotid sinus nerve inputs to neurons in the nucleus of the solitary tract
    • Mifflin S.W. Short-term potentiation of carotid sinus nerve inputs to neurons in the nucleus of the solitary tract. Respir. Physiol. 1997, 110:229-236.
    • (1997) Respir. Physiol. , vol.110 , pp. 229-236
    • Mifflin, S.W.1
  • 49
    • 79959354634 scopus 로고    scopus 로고
    • Intermittent hypoxia-induced sensitization of central chemoreceptors contributes to sympathetic nerve activity during late expiration in rats
    • Molkov Y.I., Zoccal D.B., Moraes D.J., Paton J.F., Machado B.H., Rybak I.A. Intermittent hypoxia-induced sensitization of central chemoreceptors contributes to sympathetic nerve activity during late expiration in rats. J. Neurophysiol. 2011, 105:3080-3091.
    • (2011) J. Neurophysiol. , vol.105 , pp. 3080-3091
    • Molkov, Y.I.1    Zoccal, D.B.2    Moraes, D.J.3    Paton, J.F.4    Machado, B.H.5    Rybak, I.A.6
  • 50
    • 0037381920 scopus 로고    scopus 로고
    • Abnormal vasoactive hormones and 24-hour blood pressure in obstructive sleep apnea
    • Moller D.S., Lind P., Strunge B., Pedersen E.B. Abnormal vasoactive hormones and 24-hour blood pressure in obstructive sleep apnea. Am. J. Hypertens. 2003, 16:274-280.
    • (2003) Am. J. Hypertens. , vol.16 , pp. 274-280
    • Moller, D.S.1    Lind, P.2    Strunge, B.3    Pedersen, E.B.4
  • 51
    • 33745758872 scopus 로고    scopus 로고
    • Effect of repetitive hypoxic apnoeas on baroreflex function in humans
    • Monahan K.D., Leuenberger U.A., Ray C.A. Effect of repetitive hypoxic apnoeas on baroreflex function in humans. J. Physiol. 2006, 574:605-613.
    • (2006) J. Physiol. , vol.574 , pp. 605-613
    • Monahan, K.D.1    Leuenberger, U.A.2    Ray, C.A.3
  • 52
    • 0029156225 scopus 로고
    • Combined hypoxia and hypercapnia evokes long-lasting sympathetic activation in humans
    • Morgan B.J., Crabtree D.C., Palta M., Skatrud J.B. Combined hypoxia and hypercapnia evokes long-lasting sympathetic activation in humans. J. Appl. Physiol. 1995, 79:205-213.
    • (1995) J. Appl. Physiol. , vol.79 , pp. 205-213
    • Morgan, B.J.1    Crabtree, D.C.2    Palta, M.3    Skatrud, J.B.4
  • 53
    • 0035870836 scopus 로고    scopus 로고
    • Changes in cat medullary neurone firing rates and synchrony following induction of respiratory long-term facilitation
    • Morris K.F., Shannon R., Lindsey B.G. Changes in cat medullary neurone firing rates and synchrony following induction of respiratory long-term facilitation. J. Physiol. 2001, 532:483-497.
    • (2001) J. Physiol. , vol.532 , pp. 483-497
    • Morris, K.F.1    Shannon, R.2    Lindsey, B.G.3
  • 54
    • 0032406637 scopus 로고    scopus 로고
    • Baroreflex control of sympathetic nerve activity and heart rate in obstructive sleep apnea
    • Narkiewicz K., Pesek C.A., Kato M., Phillips B.G., Davison D.E., Somers V.K. Baroreflex control of sympathetic nerve activity and heart rate in obstructive sleep apnea. Hypertension 1998, 32:1039-1043.
    • (1998) Hypertension , vol.32 , pp. 1039-1043
    • Narkiewicz, K.1    Pesek, C.A.2    Kato, M.3    Phillips, B.G.4    Davison, D.E.5    Somers, V.K.6
  • 55
    • 0032539896 scopus 로고    scopus 로고
    • Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apnea
    • Narkiewicz K., van de Borne P.J., Montano N., Dyken M.E., Phillips B.G., Somers V.K. Contribution of tonic chemoreflex activation to sympathetic activity and blood pressure in patients with obstructive sleep apnea. Circulation 1998, 97:943-945.
    • (1998) Circulation , vol.97 , pp. 943-945
    • Narkiewicz, K.1    van de Borne, P.J.2    Montano, N.3    Dyken, M.E.4    Phillips, B.G.5    Somers, V.K.6
  • 56
    • 0033534086 scopus 로고    scopus 로고
    • Nocturnal continuous positive airway pressure decreases daytime sympathetic traffic in obstructive sleep apnea
    • Narkiewicz K., Kato M., Phillips B.G., Pesek C.A., Davison D.E., Somers V.K. Nocturnal continuous positive airway pressure decreases daytime sympathetic traffic in obstructive sleep apnea. Circulation 1999, 100:2332-2335.
    • (1999) Circulation , vol.100 , pp. 2332-2335
    • Narkiewicz, K.1    Kato, M.2    Phillips, B.G.3    Pesek, C.A.4    Davison, D.E.5    Somers, V.K.6
  • 58
    • 0030218959 scopus 로고    scopus 로고
    • In vitro responses of VLM neurons to hypoxia after normobaric hypoxic acclimatization
    • Nolan P.C., Waldrop T.G. In vitro responses of VLM neurons to hypoxia after normobaric hypoxic acclimatization. Respir. Physiol. 1996, 105:23-33.
    • (1996) Respir. Physiol. , vol.105 , pp. 23-33
    • Nolan, P.C.1    Waldrop, T.G.2
  • 59
    • 0035783413 scopus 로고    scopus 로고
    • Selective cardiorespiratory and catecholaminergic areas express the hypoxia-inducible factor-1alpha (HIF-1alpha) under in vivo hypoxia in rat brainstem
    • Pascual O., Denavit-Saubie M., Dumas S., Kietzmann T., Ghilini G., Mallet J., Pequignot J.M. Selective cardiorespiratory and catecholaminergic areas express the hypoxia-inducible factor-1alpha (HIF-1alpha) under in vivo hypoxia in rat brainstem. Eur. J. Neurosci. 2001, 14:1981-1991.
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 1981-1991
    • Pascual, O.1    Denavit-Saubie, M.2    Dumas, S.3    Kietzmann, T.4    Ghilini, G.5    Mallet, J.6    Pequignot, J.M.7
  • 60
    • 0042691713 scopus 로고    scopus 로고
    • Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas
    • Peng Y.J., Overholt J.L., Kline D., Kumar G.K., Prabhakar N.R. Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:10073-10078.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 10073-10078
    • Peng, Y.J.1    Overholt, J.L.2    Kline, D.3    Kumar, G.K.4    Prabhakar, N.R.5
  • 61
    • 80054699503 scopus 로고    scopus 로고
    • Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase
    • Peng Y.J., Raghuraman G., Khan S.A., Kumar G.K., Prabhakar N.R. Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase. J. Appl. Physiol. 2011, 111:964-970.
    • (2011) J. Appl. Physiol. , vol.111 , pp. 964-970
    • Peng, Y.J.1    Raghuraman, G.2    Khan, S.A.3    Kumar, G.K.4    Prabhakar, N.R.5
  • 63
    • 0028170188 scopus 로고
    • 5-Hydoxytryptamine evokes depolarizations and membrane potential oscillations in rat sympathetic preganglionic neurones
    • Pickering A.E., Spanswick D., Logan S.D. 5-Hydoxytryptamine evokes depolarizations and membrane potential oscillations in rat sympathetic preganglionic neurones. J. Physiol. 1994, 480:109-121.
    • (1994) J. Physiol. , vol.480 , pp. 109-121
    • Pickering, A.E.1    Spanswick, D.2    Logan, S.D.3
  • 64
    • 84755161048 scopus 로고    scopus 로고
    • Spontaneous rhythmogenic capabilities of sympathetic neuronal assemblies in the rat spinal cord slice
    • Pierce M.L., Deuchars J., Deuchars S.A. Spontaneous rhythmogenic capabilities of sympathetic neuronal assemblies in the rat spinal cord slice. Neuroscience 2010, 170:827-838.
    • (2010) Neuroscience , vol.170 , pp. 827-838
    • Pierce, M.L.1    Deuchars, J.2    Deuchars, S.A.3
  • 65
    • 78049387065 scopus 로고    scopus 로고
    • Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia
    • Prabhakar N.R., Kumar G.K. Mechanisms of sympathetic activation and blood pressure elevation by intermittent hypoxia. Respir. Physiol. Neurobiol. 2010, 174:156-161.
    • (2010) Respir. Physiol. Neurobiol. , vol.174 , pp. 156-161
    • Prabhakar, N.R.1    Kumar, G.K.2
  • 66
    • 33846253979 scopus 로고    scopus 로고
    • Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia
    • Prabhakar N.R., Dick T.E., Nanduri J., Kumar G.K. Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia. Exp. Physiol. 2007, 92:39-44.
    • (2007) Exp. Physiol. , vol.92 , pp. 39-44
    • Prabhakar, N.R.1    Dick, T.E.2    Nanduri, J.3    Kumar, G.K.4
  • 67
    • 0038605887 scopus 로고    scopus 로고
    • Roles for CCK1 and 5-HT3 receptors in the effects of CCK on presympathetic vasomotor neuronal discharge in the rat
    • Saita M., Verberne A.J. Roles for CCK1 and 5-HT3 receptors in the effects of CCK on presympathetic vasomotor neuronal discharge in the rat. Br. J. Pharmacol. 2003, 139:415-423.
    • (2003) Br. J. Pharmacol. , vol.139 , pp. 415-423
    • Saita, M.1    Verberne, A.J.2
  • 68
    • 2642555563 scopus 로고    scopus 로고
    • HIF1 and oxygen sensing in the brain
    • Sharp F.R., Bernaudin M. HIF1 and oxygen sensing in the brain. Nat. Rev. Neurosci. 2004, 5:437-448.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 437-448
    • Sharp, F.R.1    Bernaudin, M.2
  • 69
    • 79952581618 scopus 로고    scopus 로고
    • Altered sympathetic reflexes and vascular reactivity in rats after exposure to chronic intermittent hypoxia
    • Silva A.Q., Schreihofer A.M. Altered sympathetic reflexes and vascular reactivity in rats after exposure to chronic intermittent hypoxia. J. Physiol. 2011, 589:1463-1476.
    • (2011) J. Physiol. , vol.589 , pp. 1463-1476
    • Silva, A.Q.1    Schreihofer, A.M.2
  • 70
    • 78049375936 scopus 로고    scopus 로고
    • Is augmented central respiratory-sympathetic coupling involved in the generation of hypertension?
    • Simms A.E., Paton J.F., Allen A.M., Pickering A.E. Is augmented central respiratory-sympathetic coupling involved in the generation of hypertension?. Respir. Physiol. Neurobiol. 2010, 174:89-97.
    • (2010) Respir. Physiol. Neurobiol. , vol.174 , pp. 89-97
    • Simms, A.E.1    Paton, J.F.2    Allen, A.M.3    Pickering, A.E.4
  • 71
    • 0027754005 scopus 로고
    • Chemoreflexes-responses, interactions and implications for sleep apnea
    • Somers V.K., Abboud F.M. Chemoreflexes-responses, interactions and implications for sleep apnea. Sleep 1993, 16:S30-S33.
    • (1993) Sleep , vol.16
    • Somers, V.K.1    Abboud, F.M.2
  • 73
    • 52149086125 scopus 로고    scopus 로고
    • Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. In collaboration with the National Heart, Lung, and Blood Institute N
    • Somers V.K., White D.P., Amin R., Abraham W.T., Costa F., Culebras A., Daniels S., Floras J.S., Hunt C.E., Olson L.J., Pickering T.G., Russell R., Woo M., Young T. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. In collaboration with the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health). Circulation 2008, 118:1080-1111.
    • (2008) Circulation , vol.118 , pp. 1080-1111
    • Somers, V.K.1    White, D.P.2    Amin, R.3    Abraham, W.T.4    Costa, F.5    Culebras, A.6    Daniels, S.7    Floras, J.S.8    Hunt, C.E.9    Olson, L.J.10    Pickering, T.G.11    Russell, R.12    Woo, M.13    Young, T.14
  • 74
    • 33646144198 scopus 로고    scopus 로고
    • Impaired control of renal sympathetic nerve activity following neonatal intermittent hypoxia in rats
    • Soukhova-O'Hare G.K., Roberts A.M., Gozal D. Impaired control of renal sympathetic nerve activity following neonatal intermittent hypoxia in rats. Neurosci. Lett. 2006, 399:181-185.
    • (2006) Neurosci. Lett. , vol.399 , pp. 181-185
    • Soukhova-O'Hare, G.K.1    Roberts, A.M.2    Gozal, D.3
  • 75
    • 0028133633 scopus 로고
    • Central neural mechanisms mediating excitation of sympathetic neurons by hypoxia
    • Sun M.K., Reis D.J. Central neural mechanisms mediating excitation of sympathetic neurons by hypoxia. Prog. Neurobiol. 1994, 44:197-219.
    • (1994) Prog. Neurobiol. , vol.44 , pp. 197-219
    • Sun, M.K.1    Reis, D.J.2
  • 76
    • 72049104808 scopus 로고    scopus 로고
    • Intermittent hypoxia induces functional recovery following cervical spinal injury
    • Vinit S., Lovett-Barr M.R., Mitchell G.S. Intermittent hypoxia induces functional recovery following cervical spinal injury. Respir. Physiol. Neurobiol. 2009, 169:210-217.
    • (2009) Respir. Physiol. Neurobiol. , vol.169 , pp. 210-217
    • Vinit, S.1    Lovett-Barr, M.R.2    Mitchell, G.S.3
  • 77
    • 0037380939 scopus 로고    scopus 로고
    • Central nervous system blockade by peripheral administration of AT1 receptor blockers
    • Wang J.M., Tan J., Leenen F.H. Central nervous system blockade by peripheral administration of AT1 receptor blockers. J. Cardiovasc. Pharmacol. 2003, 41:593-599.
    • (2003) J. Cardiovasc. Pharmacol. , vol.41 , pp. 593-599
    • Wang, J.M.1    Tan, J.2    Leenen, F.H.3
  • 79
    • 0034807744 scopus 로고    scopus 로고
    • Exposure to hypoxia produces long-lasting sympathetic activation in humans
    • Xie A., Skatrud J.B., Puleo D.S., Morgan B.J. Exposure to hypoxia produces long-lasting sympathetic activation in humans. J. Appl. Physiol. 2001, 91:1555-1562.
    • (2001) J. Appl. Physiol. , vol.91 , pp. 1555-1562
    • Xie, A.1    Skatrud, J.B.2    Puleo, D.S.3    Morgan, B.J.4
  • 80
    • 77955765792 scopus 로고    scopus 로고
    • Acute intermittent hypoxia in rat in vivo elicits a robust increase in tonic sympathetic nerve activity that is independent of respiratory drive
    • Xing T., Pilowsky P.M. Acute intermittent hypoxia in rat in vivo elicits a robust increase in tonic sympathetic nerve activity that is independent of respiratory drive. J. Physiol. 2010, 588:3075-3088.
    • (2010) J. Physiol. , vol.588 , pp. 3075-3088
    • Xing, T.1    Pilowsky, P.M.2
  • 82
    • 47249118848 scopus 로고    scopus 로고
    • Increased sympathetic outflow in juvenile rats submitted to chronic intermittent hypoxia correlates with enhanced expiratory activity
    • Zoccal D.B., Simms A.E., Bonagamba L.G., Braga V.A., Pickering A.E., Paton J.F., Machado B.H. Increased sympathetic outflow in juvenile rats submitted to chronic intermittent hypoxia correlates with enhanced expiratory activity. J. Physiol. 2008, 586:3253-3265.
    • (2008) J. Physiol. , vol.586 , pp. 3253-3265
    • Zoccal, D.B.1    Simms, A.E.2    Bonagamba, L.G.3    Braga, V.A.4    Pickering, A.E.5    Paton, J.F.6    Machado, B.H.7
  • 83
    • 68949103657 scopus 로고    scopus 로고
    • Sympathetic-mediated hypertension of awake juvenile rats submitted to chronic intermittent hypoxia is not linked to baroreflex dysfunction
    • Zoccal D.B., Bonagamba L.G., Paton J.F., Machado B.H. Sympathetic-mediated hypertension of awake juvenile rats submitted to chronic intermittent hypoxia is not linked to baroreflex dysfunction. Exp. Physiol. 2009, 94:972-983.
    • (2009) Exp. Physiol. , vol.94 , pp. 972-983
    • Zoccal, D.B.1    Bonagamba, L.G.2    Paton, J.F.3    Machado, B.H.4
  • 84
    • 80555123093 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia augments sympatho-excitatory response to ATP but not to l-glutamate in the RVLM of rats
    • Zoccal D.B., Huidobro-Toro J.P., Machado B.H. Chronic intermittent hypoxia augments sympatho-excitatory response to ATP but not to l-glutamate in the RVLM of rats. Auton. Neurosci. 2011, 165:156-162.
    • (2011) Auton. Neurosci. , vol.165 , pp. 156-162
    • Zoccal, D.B.1    Huidobro-Toro, J.P.2    Machado, B.H.3
  • 85
    • 0037155770 scopus 로고    scopus 로고
    • Brain angiotensin II: new insights into its role in sympathetic regulation
    • Zucker I.H. Brain angiotensin II: new insights into its role in sympathetic regulation. Circ. Res. 2002, 90:503-505.
    • (2002) Circ. Res. , vol.90 , pp. 503-505
    • Zucker, I.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.