How can dialyzer designs improve solute clearances for hemodialysis patients?

Hemodialysis International

Volumn 18, Issue S1, 2014, Pages S43-S47

  Davenport, Andrew ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Adsorption; Dialyzer; Diffusion; Hemodiafiltration; Hemodialysis

Indexed keywords

POLYMER; POLYSULFONE; POVIDONE; DIALYSIS FLUID;

ADSORPTION; ARTICLE; ARTIFICIAL KIDNEY; BLOOD FLOW VELOCITY; CHRONIC KIDNEY DISEASE; CLEARANCE; COMPLEMENT ACTIVATION; DIALYSATE; HEMODIAFILTRATION; HEMODIALYSIS PATIENT; HOLLOW FIBER; HYDRAULIC PERMEABILITY; OXIDATION; UREMIA; CHEMISTRY; DEVICES; EQUIPMENT DESIGN; HUMAN; PROCEDURES; RENAL REPLACEMENT THERAPY;

DIALYSIS SOLUTIONS; EQUIPMENT DESIGN; HUMANS; RENAL DIALYSIS;

EID: 84910642358     PISSN: 14927535     EISSN: 15424758     Source Type: Journal    
DOI: 10.1111/hdi.12223     Document Type: Article

References (36)

1. Twardowski ZJ. History of haemodialyzers' design. Hemodial Int. 2008; 12:173-210.
2. Kiil F. Development of parallel flow artificial kidney. Acta Chir Scand. 1960; (Suppl 253):142-150.
3. Craddock PR, Fehr J, Brigham KL, Kronenberg RS, Jacob HS. Complement and leukocyte-mediated pulmonary dysfunction in haemodialysis. N Engl J Med. 1977; 296:769-774.
4. Davenport A, Davison AM, Will EJ. Does membrane biocompatibility effect cardiovascular stability in critically ill patients treated by machine haemofiltration? Kidney Int. 1993; 43(Suppl 41):S230-S234.
5. Schiffl H, Lang SM, König A, Strasser T, Haider MC, Held E. Biocompatible membranes in acute renal failure: Prospective case-controlled study. Lancet. 1994; 344:570-572.
6. Davenport A. Can dialyzer membrane selection affect outcomes in patients with acute kidney injury requiring dialysis? Hemodial Int. 2009; 13(Suppl 1):S13-S17.
7. Davenport A. The role of dialyzer membrane flux in bio-incompatibility. Hemodial Int. 2008; 12(Suppl 2):S29-S33.
8. Ronco C, Bowry SK, Brendolan A, etal. Hemodialyzer: From macro-design to membrane nanostructure; the case of the FX-class of hemodialyzers. Kidney Int Suppl. 2002; 80:126-142.
9. Davenport A, Will EJ, Davison AM. The effect of the direction of dialysate flow on the efficiency of CAVHD. Blood Purif. 1990; 8:329-336.
10. Leypoldt JK, Kamerath CD, Gilson JF, Friederichs G. Dialyzer clearances and mass transfer-area coefficients for small solutes at low dialysate flow rates. ASAIO J. 2006; 52:404-409.
11. Davenport A. Membrane designs and composition for hemodialysis, hemofiltration and hemodialfiltration: Past, present and future. Minerva Urol Nefrol. 2010; 62:29-40.
12. Leypoldt JK, Cheung AK, Chirananthavat T, Gilson JF, Kamerath CD, Deeter RB. Hollow fiber shape alters solute clearances in high flux hemodialyzers. ASAIO J. 2003; 49:81-87.
13. Kim JC, Garzotto F, Cruz DN, etal. Computational modeling of effects of mechanical shaking on hemodynamics in hollow fibers. Int J Artif Organs. 2012; 35:301-307.
14. Gura V, Davenport A, Beizai M, Ezon C, Ronco C. Beta2-microglobulin and phosphate clearances using a wearable artificial kidney: A pilot study. Am J Kidney Dis. 2009; 54:104-111.
15. Hirano A, Kida S, Yamamoto K, Sakai K. Experimental evaluation of flow and dialysis performance of hollow-fiber dialyzers with different packing densities. J Artif Organs. 2012; 15:168-175.
16. Leypoldt JK, Cheung AK. Increases in mass transfer-area coefficients and urea Kt/V with increasing dialysate flow rate are greater for high-flux dialyzers. Am J Kidney Dis. 2001; 38:575-579.
17. Ward RA, Idoux JW, Hamdan H, Ouseph R, Depner TA, Golper TA. Dialysate flow rate and delivered Kt/Vurea for dialyzers with enhanced dialysate flow distribution. Clin J Am Soc Nephrol. 2011; 6:2235-2239.
18. Hirano A, Yamamoto K, Matsuda M, etal. Evaluation of dialyzer jacket structure and hollow-fiber dialysis membranes to achieve high dialysis performance. Ther Apher Dial. 2011; 15:66-74.
19. Yamamoto K, Matsuda M, Hirano A, etal. Computational evaluation of dialysis fluid flow in dialyzers with variously designed jackets. Artif Organs. 2009; 33:481-486.
20. Schmidt JJ, Hafer C, Clajus C, etal. New high-cutoff dialyzer allows improved middle molecule clearance without an increase in albumin loss: A clinical crossover comparison in extended dialysis. Blood Purif. 2012; 34:246-252.
21. Hutchison CA, Harding S, Mead G, etal. Serum free-light chain removal by high cutoff hemodialysis: Optimizing removal and supportive care. Artif Organs. 2008; 32:910-917.
22. Davenport A. Role of dialysis technology in the removal of uremic toxins. Hemodial Int. 2011; 15(Suppl 1):S49-S53.
23. Krieter DH, Hackl A, Rodriguez A, etal. Protein-bound uraemic toxin removal in haemodialysis and post-dilution haemodiafiltration. Nephrol Dial Transplant. 2010; 25:212-218.
24. Vernon K, Peasegood J, Riddell A, Davenport A. Dialyzers designed to increase internal filtration do not result in significantly increased platelet activation and thrombin generation. Nephron Clin Pract. 2011; 117:c403-c408.
25. Omichi M, Matsusaki M, Maruyama I, Akashi M. Improvement of blood compatibility on polysulfone-polyvinylpyrrolidone blend films as a model membrane of dialyzer by physical adsorption of recombinant soluble human thrombomodulin (ART-123). J Biomater Sci Polym Ed. 2012; 23:593-608.
26. Tattersall JE, Ward RA, EUDIAL group. Online haemodiafiltration: Definition, dose quantification and safety revisited. Nephrol Dial Transplant. 2013; 28:542-550.
27. Cross J, Davenport A. Does online hemodiafiltration lead to reduction in trace elements and vitamins? Hemodial Int. 2011; 15:509-514.
28. Schindler R, Beck W, Deppisch R, etal. Short bacterial DNA fragments: Detection in dialysate and induction of cytokines. J Am Soc Nephrol. 2004; 15:3207-3214.
29. DeAngelis RA, Reis ES, Ricklin D, Lambris JD. Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysis. Immunobiology. 2012; 217:1097-1105.
30. Davenport A. Optimization of heparin anticoagulation for haemodialysis. Hemodial Int. 2011; 15(Suppl 1):S43-S48.
31. Lavaud S, Paris B, Maheut H, etal. Assessment of the heparin-binding AN69 ST hemodialysis membrane: II. Clinical studies without heparin administration. ASAIO J. 2005; 51:348-351.
32. Ferraro B, Galli F, Frei B, etal. Peroxynitrite-induced oxidation of plasma lipids is enhanced in stable haemodialysis patients. Kidney Int. 2003; 63:2207-2213.
33. Betjes MG, Hoekstra FM, Klepper M, Postma SM, Vaessen LM. Vitamin E-coated dialyzer membranes down regulate expression of monocyte adhesion and co-stimulatory molecules. Blood Purif. 2004; 22:510-517.
34. Tijink MS, Wester M, Glorieux G, etal. Mixed matrix hollow fiber membranes for removal of protein-bound toxins from human plasma. Biomaterials. 2013; 34:7819-7828.
35. Tuhy AR, Anderson EK, Jovanovic GN. Urea separation in flat-plate microchannel hemodialyzer; experiment and modelling. Biomed Microdevices. 2012; 14:595-602.
36. Davenport A. Intradialytic complications during haemodialysis. Hemodial Int. 2006; 10:162-167.