A novel immuno-competitive capture mass spectrometry strategy for protein-protein interaction profiling reveals that LATS kinases regulate HCV replication through NS5A phosphorylation

Molecular and Cellular Proteomics

Volumn 13, Issue 11, 2014, Pages 3040-3048

  Meistermann, Hélène ^a   Gao, Junjun ^b   Golling, Sabrina ^a   Lamerz, Jens ^a   Le Pogam, Sophie ^b   Tzouros, Manuel ^a   Sankabathula, Sailaja ^b   Gruenbaum, Lore ^b   Nájera, Isabel ^b   Langen, Hanno ^a   Klumpp, Klaus ^b   Augustin, Angélique ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; LARGE TUMOR SUPPRESSOR HOMOLOG 1; LARGE TUMOR SUPPRESSOR HOMOLOG 2; NONSTRUCTURAL PROTEIN 5A; PROTEIN KINASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; LATS1 PROTEIN, HUMAN; LATS2 PROTEIN, HUMAN; NS-5 PROTEIN, HEPATITIS C VIRUS; PHOSPHATIDYLINOSITOL PHOSPHATE 4-KINASE; PHOSPHOTRANSFERASE; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; PROTEOME; SMALL INTERFERING RNA; VIRUS PROTEIN;

ARTICLE; CELL INTERACTION; CELL LYSATE; CONTROLLED STUDY; FOLLOW UP; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOCOMPETITIVE CAPTURE MASS SPECTROMETRY; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STATISTICAL ANALYSIS; TANDEM MASS SPECTROMETRY; VIRUS REPLICATION; CELL LINE; DNA REPLICATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEPACIVIRUS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES; PROTEIN ANALYSIS; PROTEIN TERTIARY STRUCTURE; RNA INTERFERENCE; VIRUS GENOME;

HEPATITIS C VIRUS;

CELL LINE; DNA REPLICATION; GENOME, VIRAL; HEPACIVIRUS; HUMANS; MASS SPECTROMETRY; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEOME; RNA INTERFERENCE; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEINS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

EID: 84910633227     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M113.028977     Document Type: Article

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