Arginase 2 deficiency prevents oxidative stress and limits hyperoxia-induced retinal vascular degeneration

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Suwanpradid, Jutamas ^a   Rojas, Modesto ^a   Behzadian, M Ali ^a   Caldwell, R William ^a   Caldwell, Ruth B ^a,b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; ARGINASE; ARGINASE 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; ARG2 PROTEIN, MOUSE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; PEROXYNITROUS ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARGINASE 2 GENE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE; GENE DELETION; GENE EXPRESSION; HYPERARGININEMIA; MOLECULAR IMAGING; MOUSE; NONHUMAN; OXIDATIVE STRESS; RETINA CELL; RETINA NEOVASCULARIZATION; RETROLENTAL FIBROPLASIA; ANIMAL; ANTAGONISTS AND INHIBITORS; BOVINE; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENETICS; HUMAN; HYPEROXIA; METABOLISM; NEWBORN; PATHOLOGY; RETINA; RETINAL DEGENERATION; RETINAL NEOVASCULARIZATION; RETINOPATHY OF PREMATURITY;

ANIMALS; APOPTOSIS; ARGINASE; CATTLE; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; HUMANS; HYPEROXIA; INFANT, NEWBORN; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PEROXYNITROUS ACID; REACTIVE OXYGEN SPECIES; RETINA; RETINAL DEGENERATION; RETINAL NEOVASCULARIZATION; RETINOPATHY OF PREMATURITY; SUPEROXIDES;

EID: 84910625006     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110604     Document Type: Article

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