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Volumn 53, Issue 11, 2012, Pages 6833-6850

eNOS overexpression exacerbates vascular closure in the obliterative phase of OIR and increases angiogenic drive in the subsequent proliferative stage

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GREEN FLUORESCENT PROTEIN; NITRIC OXIDE SYNTHASE; NITRITE; OXYGEN; REACTIVE OXYGEN METABOLITE; TETRAHYDROBIOPTERIN; VASCULOTROPIN; NOS3 PROTEIN, MOUSE;

EID: 84871853431     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-9797     Document Type: Article
Times cited : (19)

References (50)
  • 1
    • 0028123090 scopus 로고
    • Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy
    • Adamis AP, Miller JW, Bernal MT, et al. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol. 1994; 118:445-450.
    • (1994) Am J Ophthalmol. , vol.118 , pp. 445-450
    • Adamis, A.P.1    Miller, J.W.2    Bernal, M.T.3
  • 2
    • 0027942607 scopus 로고
    • Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders
    • Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med. 1994; 331:1480-1487.
    • (1994) N Engl J Med. , vol.331 , pp. 1480-1487
    • Aiello, L.P.1    Avery, R.L.2    Arrigg, P.G.3
  • 3
    • 0028815295 scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization
    • Pierce E, Avery R, Foley E, Aiello L, Smith L. Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization. Proc Natl Acad Sci U S A. 1995;92:905-909.
    • (1995) Proc Natl Acad Sci U S A. , vol.92 , pp. 905-909
    • Pierce, E.1    Avery, R.2    Foley, E.3    Aiello, L.4    Smith, L.5
  • 4
    • 0029074024 scopus 로고
    • Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia
    • Stone J, Itin A, Alon T, et al. Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J Neurosci. 1995;15: 4738-4747.
    • (1995) J Neurosci. , vol.15 , pp. 4738-4747
    • Stone, J.1    Itin, A.2    Alon, T.3
  • 5
    • 0033882794 scopus 로고    scopus 로고
    • Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization
    • Ozaki H, Seo M-S, Ozaki K, et al. Blockade of vascular endothelial cell growth factor receptor signaling is sufficient to completely prevent retinal neovascularization. Am J Pathol. 2000;156:697-707.
    • (2000) Am J Pathol. , vol.156 , pp. 697-707
    • Ozaki, H.1    Seo, M.-S.2    Ozaki, K.3
  • 6
    • 56149103354 scopus 로고    scopus 로고
    • Endogenous VEGF is required for visual function: Evidence for a survival role on Muller cells and photoreceptors
    • Saint-Geniez M, Maharaj ASR, Walshe TE, et al. Endogenous VEGF is required for visual function: evidence for a survival role on Muller cells and photoreceptors. PLoS ONE. 2008;3: e3554.
    • (2008) PLoS ONE. , vol.3
    • Saint-Geniez, M.1    Maharaj, A.S.R.2    Walshe, T.E.3
  • 7
    • 0035103934 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase mediates the change from retinal to vitreal neovascularization in ischemic retinopathy
    • Sennlaub F, Courtois Y, Goureau O. Inducible nitric oxide synthase mediates the change from retinal to vitreal neovascularization in ischemic retinopathy. J Clin Invest. 2001;107: 717-725.
    • (2001) J Clin Invest. , vol.107 , pp. 717-725
    • Sennlaub, F.1    Courtois, Y.2    Goureau, O.3
  • 8
    • 13244257265 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-α improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy
    • Gardiner TA, Gibson DS, de Gooyer TE, de la Cruz VF, McDonald DM, Stitt AW. Inhibition of tumor necrosis factor-α improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy. Am J Pathol. 2005;166:637-644.
    • (2005) Am J Pathol. , vol.166 , pp. 637-644
    • Gardiner, T.A.1    Gibson, D.S.2    de Gooyer, T.E.3    de la Cruz, V.F.4    McDonald, D.M.5    Stitt, A.W.6
  • 9
    • 2642597076 scopus 로고    scopus 로고
    • Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells
    • Papapetropoulos A, García-Cardeña G, Madri J, Sessa W. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest. 1997;100:3131-3139.
    • (1997) J Clin Invest. , vol.100 , pp. 3131-3139
    • Papapetropoulos, A.1    García-Cardeña, G.2    Madri, J.3    Sessa, W.4
  • 10
    • 0031008458 scopus 로고    scopus 로고
    • Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis
    • Ziche M, Morbidelli L, Choudhuri R, et al. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis. J Clin Invest. 1997;99:2625-2634.
    • (1997) J Clin Invest. , vol.99 , pp. 2625-2634
    • Ziche, M.1    Morbidelli, L.2    Choudhuri, R.3
  • 11
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature. 1999;399: 601-605.
    • (1999) Nature. , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 13
    • 0035171032 scopus 로고    scopus 로고
    • Reduced severity of oxygeninduced retinopathy in eNOS-deficient mice
    • Brooks SE, Gu X, Samuel S, et al. Reduced severity of oxygeninduced retinopathy in eNOS-deficient mice. Invest Ophthalmol Vis Sci. 2001;42:222-228.
    • (2001) Invest Ophthalmol Vis Sci. , vol.42 , pp. 222-228
    • Brooks, S.E.1    Gu, X.2    Samuel, S.3
  • 14
    • 0036197157 scopus 로고    scopus 로고
    • Nitric oxide is proangiogenic in the retina and choroid
    • Ando A, Yang A, Mori K, et al. Nitric oxide is proangiogenic in the retina and choroid. J Cell Physiol. 2002;191:116-124.
    • (2002) J Cell Physiol. , vol.191 , pp. 116-124
    • Ando, A.1    Yang, A.2    Mori, K.3
  • 15
    • 0037219525 scopus 로고    scopus 로고
    • Enhancement of ischemiainduced angiogenesis by eNOS overexpression
    • Amano K, Matsubara H, Iba O, et al. Enhancement of ischemiainduced angiogenesis by eNOS overexpression. Hypertension. 2003;41:156-162.
    • (2003) Hypertension. , vol.41 , pp. 156-162
    • Amano, K.1    Matsubara, H.2    Iba, O.3
  • 16
    • 0242361643 scopus 로고    scopus 로고
    • Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model
    • Namba T, Koike H, Murakami K, et al. Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model. Circulation. 2003;108:2250-2257.
    • (2003) Circulation. , vol.108 , pp. 2250-2257
    • Namba, T.1    Koike, H.2    Murakami, K.3
  • 17
    • 0029074024 scopus 로고
    • Development of retinal vasculature is mediated by hypoxia-induced endothelial growth factor expression by neuroglia
    • Stone J. Development of retinal vasculature is mediated by hypoxia-induced endothelial growth factor expression by neuroglia. J Neurosci. 1995;15:4738-4747.
    • (1995) J Neurosci. , vol.15 , pp. 4738-4747
    • Stone, J.1
  • 18
    • 0037815292 scopus 로고    scopus 로고
    • VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia
    • Gerhardt H, Golding M, Fruttiger M, et al. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J Cell Biol. 2003;161:1163-1177.
    • (2003) J Cell Biol. , vol.161 , pp. 1163-1177
    • Gerhardt, H.1    Golding, M.2    Fruttiger, M.3
  • 19
    • 0032475865 scopus 로고    scopus 로고
    • Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • Xia Y, Tsai AL, Berka V, Zweier JL. Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem. 1998;273:25804-25808.
    • (1998) J Biol Chem. , vol.273 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 20
    • 17844364194 scopus 로고    scopus 로고
    • New insights into the retinal circulation: Inflammatory lipid mediators in ischemic retinopathy
    • Hardy P, Beauchamp M, Sennlaub F, et al. New insights into the retinal circulation: inflammatory lipid mediators in ischemic retinopathy. Prostaglandins Leukot Essent Fatty Acids. 2005; 72:301-325.
    • (2005) Prostaglandins Leukot Essent Fatty Acids. , vol.72 , pp. 301-325
    • Hardy, P.1    Beauchamp, M.2    Sennlaub, F.3
  • 21
    • 45549090431 scopus 로고    scopus 로고
    • Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model
    • Saito Y, Uppal A, Byfield G, Budd S, Hartnett ME. Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model. Invest Ophthalmol Vis Sci. 2008;49:1591-1598.
    • (2008) Invest Ophthalmol Vis Sci. , vol.49 , pp. 1591-1598
    • Saito, Y.1    Uppal, A.2    Byfield, G.3    Budd, S.4    Hartnett, M.E.5
  • 22
    • 34247395052 scopus 로고    scopus 로고
    • Hyperoxia inhibits several critical aspects of vascular development
    • Uno K, Merges CA, Grebe R, Lutty GA, Prow TW. Hyperoxia inhibits several critical aspects of vascular development. Dev Dyn. 2007;236:981-990.
    • (2007) Dev Dyn. , vol.236 , pp. 981-990
    • Uno, K.1    Merges, C.A.2    Grebe, R.3    Lutty, G.A.4    Prow, T.W.5
  • 23
    • 28644431994 scopus 로고    scopus 로고
    • Transarachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration
    • Kermorvant-Duchemin E, Sennlaub F, Sirinyan M, et al. Transarachidonic acids generated during nitrative stress induce a thrombospondin-1-dependent microvascular degeneration. Nat Med. 2005;11:1339-1345.
    • (2005) Nat Med. , vol.11 , pp. 1339-1345
    • Kermorvant-Duchemin, E.1    Sennlaub, F.2    Sirinyan, M.3
  • 24
    • 0035814951 scopus 로고    scopus 로고
    • Endothelial regulation of vasomotion in apoE-deficient mice: Implications for interactions between peroxynitrite and tetrahydrobiopterin
    • Laursen JB, Somers M, Kurz S, et al. Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin. Circulation. 2001;103:1282-1288.
    • (2001) Circulation. , vol.103 , pp. 1282-1288
    • Laursen, J.B.1    Somers, M.2    Kurz, S.3
  • 25
    • 0036330231 scopus 로고    scopus 로고
    • Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice
    • Ozaki M, Kawashima S, Yamashita T, et al. Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice. J Clin Invest. 2002; 110:331-340.
    • (2002) J Clin Invest. , vol.110 , pp. 331-340
    • Ozaki, M.1    Kawashima, S.2    Yamashita, T.3
  • 26
    • 2242491782 scopus 로고    scopus 로고
    • Reduction of blood pressure, plasma cholesterol, and atherosclerosis by elevated endothelial nitric oxide
    • van Haperen R, de Waard M, van Deel E, et al. Reduction of blood pressure, plasma cholesterol, and atherosclerosis by elevated endothelial nitric oxide. J Biol Chem. 2002;277: 48803-48807.
    • (2002) J Biol Chem. , vol.277 , pp. 48803-48807
    • van Haperen, R.1    de Waard, M.2    van Deel, E.3
  • 27
    • 0141648341 scopus 로고    scopus 로고
    • Functional expression of endothelial nitric oxide synthase fused to green fluorescent protein in transgenic mice
    • van Haperen R, Cheng C, Mees BME, et al. Functional expression of endothelial nitric oxide synthase fused to green fluorescent protein in transgenic mice. Am J Pathol. 2003; 163:1677-1686.
    • (2003) Am J Pathol. , vol.163 , pp. 1677-1686
    • van Haperen, R.1    Cheng, C.2    Mees, B.M.E.3
  • 28
    • 28444449470 scopus 로고    scopus 로고
    • Shear stress affects the intracellular distribution of eNOS: Direct demonstration by a novel in vivo technique
    • Cheng C, van Haperen R, de Waard M, et al. Shear stress affects the intracellular distribution of eNOS: direct demonstration by a novel in vivo technique. Blood. 2005;106:3691-3698.
    • (2005) Blood. , vol.106 , pp. 3691-3698
    • Cheng, C.1    van Haperen, R.2    de Waard, M.3
  • 30
    • 77953260611 scopus 로고    scopus 로고
    • Reduced nitrooxidative stress and neural cell death suggests a protective role for microglial cells in TNF-/-mice in ischemic retinopathy
    • Stevenson L, Matesanz N, Colhoun L, et al. Reduced nitrooxidative stress and neural cell death suggests a protective role for microglial cells in TNF-/-mice in ischemic retinopathy. Invest Ophthalmol Vis Sc. 2010;51:3291-3299.
    • (2010) Invest Ophthalmol Vis Sc. , vol.51 , pp. 3291-3299
    • Stevenson, L.1    Matesanz, N.2    Colhoun, L.3
  • 31
    • 79955978712 scopus 로고    scopus 로고
    • Docosahexaenoic acid improves the nitroso-redox balance and reduces VEGF mediated angiogenic signaling in microvascular endothelial cells
    • Matesanz N, Park G, McAllister H, et al. Docosahexaenoic acid improves the nitroso-redox balance and reduces VEGF mediated angiogenic signaling in microvascular endothelial cells. Invest Ophthalmol Vis Sci. 2010;51:6815-6825.
    • (2010) Invest Ophthalmol Vis Sci. , vol.51 , pp. 6815-6825
    • Matesanz, N.1    Park, G.2    McAllister, H.3
  • 32
    • 11244262363 scopus 로고    scopus 로고
    • Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration
    • Suchting S, Heal P, Tahtis K, Stewart LM, Bicknell R. Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration. FASEB J. 2004;19:121-123.
    • (2004) FASEB J. , vol.19 , pp. 121-123
    • Suchting, S.1    Heal, P.2    Tahtis, K.3    Stewart, L.M.4    Bicknell, R.5
  • 33
    • 0039397709 scopus 로고    scopus 로고
    • Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the NOS caveolin binding domain in vivo
    • Garcia-Cardena G, Martasek P, Masters BS, et al. Dissecting the interaction between nitric oxide synthase (NOS) and caveolin. Functional significance of the NOS caveolin binding domain in vivo. J Biol Chem. 1997;272:25437-25440.
    • (1997) J Biol Chem. , vol.272 , pp. 25437-25440
    • Garcia-Cardena, G.1    Martasek, P.2    Masters, B.S.3
  • 34
    • 0030953208 scopus 로고    scopus 로고
    • Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin
    • Michel JB, Feron O, Sacks D, Michel T. Reciprocal regulation of endothelial nitric-oxide synthase by Ca2+-calmodulin and caveolin. J Biol Chem. 1997;272:15583-15586.
    • (1997) J Biol Chem. , vol.272 , pp. 15583-15586
    • Michel, J.B.1    Feron, O.2    Sacks, D.3    Michel, T.4
  • 35
    • 0029901663 scopus 로고    scopus 로고
    • Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation-implications for nitric oxide signaling
    • Garcia-Cardena G, Oh P, Liu JW, Schnitzer JE, Sessa WC. Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation-implications for nitric oxide signaling. Proc Natl Acad Sci U S A. 1996;93:6448-6453.
    • (1996) Proc Natl Acad Sci U S A. , vol.93 , pp. 6448-6453
    • Garcia-Cardena, G.1    Oh, P.2    Liu, J.W.3    Schnitzer, J.E.4    Sessa, W.C.5
  • 36
    • 0030853953 scopus 로고    scopus 로고
    • Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity
    • Ju H, Zou R, Venema VJ, Venema RC. Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity. J Biol Chem. 1997;272:18522-18525.
    • (1997) J Biol Chem. , vol.272 , pp. 18522-18525
    • Ju, H.1    Zou, R.2    Venema, V.J.3    Venema, R.C.4
  • 37
    • 0033542414 scopus 로고    scopus 로고
    • Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
    • Fulton D, Gratton J-P, McCabe TJ, et al. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature. 1999;399:597-601.
    • (1999) Nature. , vol.399 , pp. 597-601
    • Fulton, D.1    Gratton, J.-P.2    McCabe, T.J.3
  • 38
    • 11144222283 scopus 로고    scopus 로고
    • Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells
    • McDonald D, Alp N, Channon K. Functional comparison of the endothelial nitric oxide synthase Glu298Asp polymorphic variants in human endothelial cells. Pharmacogenetics. 2004; 14:831-839.
    • (2004) Pharmacogenetics. , vol.14 , pp. 831-839
    • McDonald, D.1    Alp, N.2    Channon, K.3
  • 39
    • 0029005204 scopus 로고
    • The effect of oxygen on vasoformative cell division. Evidence that "physiological hypoxia" is the stimulus for normal retinal vasculogenesis
    • Chan-Ling T, Gock B, Stone J. The effect of oxygen on vasoformative cell division. Evidence that "physiological hypoxia" is the stimulus for normal retinal vasculogenesis. Invest Ophthalmol Vis Sci. 1995;36:1201-1214.
    • (1995) Invest Ophthalmol Vis Sci. , vol.36 , pp. 1201-1214
    • Chan-Ling, T.1    Gock, B.2    Stone, J.3
  • 40
    • 0035956947 scopus 로고    scopus 로고
    • Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability
    • Fukumura D, Gohongi T, Kadambi A, et al. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci U S A. 2001;98:2604-2609.
    • (2001) Proc Natl Acad Sci U S A. , vol.98 , pp. 2604-2609
    • Fukumura, D.1    Gohongi, T.2    Kadambi, A.3
  • 41
    • 22144456034 scopus 로고    scopus 로고
    • NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels
    • Kashiwagi S, Izumi Y, Gohongi T, et al. NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels. J Clin Invest. 2005;115: 1816-1827.
    • (2005) J Clin Invest. , vol.115 , pp. 1816-1827
    • Kashiwagi, S.1    Izumi, Y.2    Gohongi, T.3
  • 42
    • 33750629961 scopus 로고    scopus 로고
    • A VEGF165-induced phenotypic switch from increased vessel density to increased vessel diameter and increased endothelial NOS activity
    • Parsons-Wingerter P, Chandrasekharan UM, McKay TL, et al. A VEGF165-induced phenotypic switch from increased vessel density to increased vessel diameter and increased endothelial NOS activity. Microvasc Res. 2006;72:91-100.
    • (2006) Microvasc Res. , vol.72 , pp. 91-100
    • Parsons-Wingerter, P.1    Chandrasekharan, U.M.2    McKay, T.L.3
  • 43
    • 0036954803 scopus 로고    scopus 로고
    • Novel role of gp91phoxcontaining NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis
    • Ushio-Fukai M, Tang Y, Fukai T, et al. Novel role of gp91phoxcontaining NAD(P)H oxidase in vascular endothelial growth factor-induced signaling and angiogenesis. Circ Res. 2002;91: 1160-1167.
    • (2002) Circ Res. , vol.91 , pp. 1160-1167
    • Ushio-Fukai, M.1    Tang, Y.2    Fukai, T.3
  • 44
    • 25144513156 scopus 로고    scopus 로고
    • Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy
    • Al-Shabrawey M, Bartoli M, El-Remessy AB, et al. Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy. Am J Pathol. 2005;167:599-607.
    • (2005) Am J Pathol. , vol.167 , pp. 599-607
    • Al-Shabrawey, M.1    Bartoli, M.2    El-Remessy, A.B.3
  • 45
    • 34547788817 scopus 로고    scopus 로고
    • Peroxynitrite mediates VEGF's angiogenic signal and function via a nitrationindependent mechanism in endothelial cells
    • El-Remessy AB, Al-Shabrawey M, Platt DH, et al. Peroxynitrite mediates VEGF's angiogenic signal and function via a nitrationindependent mechanism in endothelial cells. Am J Pathol. 2007;21:2528-2539.
    • (2007) Am J Pathol. , vol.21 , pp. 2528-2539
    • El-Remessy, A.B.1    Al-Shabrawey, M.2    Platt, D.H.3
  • 46
    • 33746641678 scopus 로고    scopus 로고
    • NADPH oxidasederived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes
    • Ebrahimian TG, Heymes C, You D, et al. NADPH oxidasederived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes. Am J Pathol. 2006;169:719-728.
    • (2006) Am J Pathol. , vol.169 , pp. 719-728
    • Ebrahimian, T.G.1    Heymes, C.2    You, D.3
  • 47
    • 52749092933 scopus 로고    scopus 로고
    • Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation
    • Li Calzi S, Purich DL, Chang KH, et al. Carbon monoxide and nitric oxide mediate cytoskeletal reorganization in microvascular cells via vasodilator-stimulated phosphoprotein phosphorylation. Diabetes. 2008;57:2488-2494.
    • (2008) Diabetes. , vol.57 , pp. 2488-2494
    • Li Calzi, S.1    Purich, D.L.2    Chang, K.H.3
  • 48
    • 70349579202 scopus 로고    scopus 로고
    • Nox2-containing NADPH oxidase deficiency confers protection from hindlimb ischemia in conditions of increased oxidative stress
    • Haddad P, Dussault S, Groleau J, et al. Nox2-containing NADPH oxidase deficiency confers protection from hindlimb ischemia in conditions of increased oxidative stress. Arterioscler Thromb Vasc Biol. 2009;29:1522-1528.
    • (2009) Arterioscler Thromb Vasc Biol. , vol.29 , pp. 1522-1528
    • Haddad, P.1    Dussault, S.2    Groleau, J.3
  • 49
    • 27644537902 scopus 로고    scopus 로고
    • Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: Insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression
    • Bendall JK, Alp NJ, Warrick N, et al. Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression. Circ Res. 2005;97: 864-871.
    • (2005) Circ Res. , vol.97 , pp. 864-871
    • Bendall, J.K.1    Alp, N.J.2    Warrick, N.3
  • 50
    • 34250836426 scopus 로고    scopus 로고
    • A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression
    • Takaya T, Hirata K-I, Yamashita T, et al. A specific role for eNOS-derived reactive oxygen species in atherosclerosis progression. Arterioscler Thromb Vasc Biol. 2007;27:1632-1637.
    • (2007) Arterioscler Thromb Vasc Biol. , vol.27 , pp. 1632-1637
    • Takaya, T.1    Hirata, K.-I.2    Yamashita, T.3


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