-
1
-
-
0036284423
-
Activated mitogen-activated protein kinase expression during human breast tumorigenesis and breast cancer progression
-
COI: 1:CAS:528:DC%2BD38Xlt1CrtLo%3D
-
Adeyinka A, Nui Y, Cherlet T, Snell L, Watson PH, Murphy LC (2002) Activated mitogen-activated protein kinase expression during human breast tumorigenesis and breast cancer progression. Clin Cancer Res 8:1747–1753
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1747-1753
-
-
Adeyinka, A.1
Nui, Y.2
Cherlet, T.3
Snell, L.4
Watson, P.H.5
Murphy, L.C.6
-
2
-
-
84863171522
-
OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing
-
Booth L, Cazanave SC, Hamed HA, Yacoub A, Ogretmen B, Chen CS, Grant S, Dent P (2012) OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing. Cancer Biol Ther 13:224–236. doi:10.4161/cbt.13.4.18877
-
(2012)
Cancer Biol Ther
, vol.13
, pp. 224-236
-
-
Booth, L.1
Cazanave, S.C.2
Hamed, H.A.3
Yacoub, A.4
Ogretmen, B.5
Chen, C.S.6
Grant, S.7
Dent, P.8
-
3
-
-
84859962402
-
GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells
-
COI: 1:CAS:528:DC%2BC38XmsVGgtL0%3D
-
Chang YJ, Huang YP, Li ZL, Chen CH (2012) GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells. PLoS One 7:e35123. doi:10.1371/journal.pone.0035123
-
(2012)
PLoS One
, vol.7
, pp. e35123
-
-
Chang, Y.J.1
Huang, Y.P.2
Li, Z.L.3
Chen, C.H.4
-
4
-
-
39049160268
-
Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development
-
Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS (2008) Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Res 68:498–505. doi:10.1158/0008-5472.CAN-07-2950
-
(2008)
Cancer Res
, vol.68
, pp. 498-505
-
-
Dong, D.1
Ni, M.2
Li, J.3
Xiong, S.4
Ye, W.5
Virrey, J.J.6
Mao, C.7
Ye, R.8
Wang, M.9
Pen, L.10
Dubeau, L.11
Groshen, S.12
Hofman, F.M.13
Lee, A.S.14
-
5
-
-
0032793067
-
B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway
-
COI: 1:CAS:528:DyaK1MXkvVKjsrg%3D
-
Erhardt P, Schremser EJ, Cooper GM (1999) B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway. Mol Cell Biol 19:5308–5315
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5308-5315
-
-
Erhardt, P.1
Schremser, E.J.2
Cooper, G.M.3
-
6
-
-
84878867532
-
Inhibition of GRP78 expression reverses cisplatin resistance in human ovarian cancer
-
COI: 1:CAS:528:DC%2BC3sXhtlGntLbN
-
Fan LM, Su J, Dong H, Wei M, Cui MH (2013) Inhibition of GRP78 expression reverses cisplatin resistance in human ovarian cancer. Zhonghua Yi Xue Za Zhi 93:1341–1344
-
(2013)
Zhonghua Yi Xue Za Zhi
, vol.93
, pp. 1341-1344
-
-
Fan, L.M.1
Su, J.2
Dong, H.3
Wei, M.4
Cui, M.H.5
-
7
-
-
70349562390
-
Chemoprophylaxis for colorectal cancer: opportunities and challenges
-
Fang JY (2009) Chemoprophylaxis for colorectal cancer: opportunities and challenges. Zhonghua Nei Ke Za Zhi 48:93–94
-
(2009)
Zhonghua Nei Ke Za Zhi
, vol.48
, pp. 93-94
-
-
Fang, J.Y.1
-
8
-
-
84881032285
-
GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy
-
Firczuk M, Gabrysiak M, Barankiewicz J, Domagala A, Nowis D, Kujawa M, Jankowska-Steifer E, Wachowska M, Glodkowska-Mrowka E, Korsak B, Winiarska M, Golab J (2013) GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy. Cell Death Dis 4:e741. doi:10.1038/cddis.2013.265
-
(2013)
Cell Death Dis
, vol.e741
, pp. 4
-
-
Firczuk, M.1
Gabrysiak, M.2
Barankiewicz, J.3
Domagala, A.4
Nowis, D.5
Kujawa, M.6
Jankowska-Steifer, E.7
Wachowska, M.8
Glodkowska-Mrowka, E.9
Korsak, B.10
Winiarska, M.11
Golab, J.12
-
9
-
-
58049209726
-
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium
-
COI: 1:CAS:528:DC%2BD1cXhsFamu7vF
-
Fu Y, Wey S, Wang M, Ye R, Liao CP, Roy-Burman P, Lee AS (2008) Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium. Proc Natl Acad Sci USA 105:19444–19449. doi:10.1073/pnas.0807691105
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19444-19449
-
-
Fu, Y.1
Wey, S.2
Wang, M.3
Ye, R.4
Liao, C.P.5
Roy-Burman, P.6
Lee, A.S.7
-
10
-
-
84899578117
-
Unexpected low-dose toxicity of the universal solvent DMSO
-
COI: 1:CAS:528:DC%2BC2cXks1Sgs7Y%3D
-
Galvao J, Davis B, Tilley M, Normando E, Duchen MR, Cordeiro MF (2014) Unexpected low-dose toxicity of the universal solvent DMSO. FASEB J 28:1317–1330. doi:10.1096/fj.13-235440
-
(2014)
FASEB J
, vol.28
, pp. 1317-1330
-
-
Galvao, J.1
Davis, B.2
Tilley, M.3
Normando, E.4
Duchen, M.R.5
Cordeiro, M.F.6
-
11
-
-
77954174203
-
Association between epidural analgesia and cancer recurrence after colorectal cancer surgery
-
Gottschalk A, Ford JG, Regelin CC, You J, Mascha EJ, Sessler DI, Durieux ME, Nemergut EC (2010) Association between epidural analgesia and cancer recurrence after colorectal cancer surgery. Anesthesiology 113:27–34. doi:10.1097/ALN.0b013e3181de6d0d
-
(2010)
Anesthesiology
, vol.113
, pp. 27-34
-
-
Gottschalk, A.1
Ford, J.G.2
Regelin, C.C.3
You, J.4
Mascha, E.J.5
Sessler, D.I.6
Durieux, M.E.7
Nemergut, E.C.8
-
12
-
-
0036437307
-
Transcriptional and translational control in the mammalian unfolded protein response
-
COI: 1:CAS:528:DC%2BD38XptVOqs70%3D
-
Harding HP, Calfon M, Urano F, Novoa I, Ron D (2002) Transcriptional and translational control in the mammalian unfolded protein response. Annu Rev Cell Dev Biol 18:575–599. doi:10.1146/annurev.cellbio.18.011402.160624
-
(2002)
Annu Rev Cell Dev Biol
, vol.18
, pp. 575-599
-
-
Harding, H.P.1
Calfon, M.2
Urano, F.3
Novoa, I.4
Ron, D.5
-
13
-
-
84870005734
-
Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity
-
COI: 1:CAS:528:DC%2BC38XhsVeitLvE
-
Hardy B, Raiter A, Yakimov M, Vilkin A, Niv Y (2012) Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity. Cell Oncol (Dordr) 35:345–354. doi:10.1007/s13402-012-0094-4
-
(2012)
Cell Oncol (Dordr)
, vol.35
, pp. 345-354
-
-
Hardy, B.1
Raiter, A.2
Yakimov, M.3
Vilkin, A.4
Niv, Y.5
-
14
-
-
35448958407
-
Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis
-
COI: 1:CAS:528:DC%2BD2sXhtFOnsb%2FL
-
Jiang CC, Chen LH, Gillespie S, Wang YF, Kiejda KA, Zhang XD, Hersey P (2007) Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis. Cancer Res 67:9750–9761. doi:10.1158/0008-5472.CAN-07-2047
-
(2007)
Cancer Res
, vol.67
, pp. 9750-9761
-
-
Jiang, C.C.1
Chen, L.H.2
Gillespie, S.3
Wang, Y.F.4
Kiejda, K.A.5
Zhang, X.D.6
Hersey, P.7
-
15
-
-
84865722080
-
The antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stress
-
Jin HR, Zhao J, Zhang Z, Liao Y, Wang CZ, Huang WH, Li SP, He TC, Yuan CS, Du W (2012) The antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stress. Cell Death Dis 3:e376. doi:10.1038/cddis.2012.122
-
(2012)
Cell Death Dis
, vol.e376
, pp. 3
-
-
Jin, H.R.1
Zhao, J.2
Zhang, Z.3
Liao, Y.4
Wang, C.Z.5
Huang, W.H.6
Li, S.P.7
He, T.C.8
Yuan, C.S.9
Du, W.10
-
16
-
-
34248571826
-
GRP78 induction in cancer: therapeutic and prognostic implications
-
COI: 1:CAS:528:DC%2BD2sXkt1KjtLo%3D
-
Lee AS (2007) GRP78 induction in cancer: therapeutic and prognostic implications. Cancer Res 67:3496–3499. doi:10.1158/0008-5472.CAN-07-0325
-
(2007)
Cancer Res
, vol.67
, pp. 3496-3499
-
-
Lee, A.S.1
-
17
-
-
84885042254
-
GRP78 mediates radiation resistance of a stem cell-like subpopulation within the MCF-7 breast cancer cell line
-
COI: 1:CAS:528:DC%2BC3sXhsl2htbzP
-
Li B, Cheng XL, Yang YP, Li ZQ (2013) GRP78 mediates radiation resistance of a stem cell-like subpopulation within the MCF-7 breast cancer cell line. Oncol Rep 30:2119–2126. doi:10.3892/or.2013.2710
-
(2013)
Oncol Rep
, vol.30
, pp. 2119-2126
-
-
Li, B.1
Cheng, X.L.2
Yang, Y.P.3
Li, Z.Q.4
-
18
-
-
34547113328
-
Serum matrix metalloproteinase 7 levels identifies poor prognosis advanced colorectal cancer patients
-
Maurel J, Nadal C, Garcia-Albeniz X, Gallego R, Carcereny E, Almendro V, Mármol M, Gallardo E, Maria Augé J, Longarón R, Martínez-Fernandez A, Molina R, Castells A, Gascón P (2007) Serum matrix metalloproteinase 7 levels identifies poor prognosis advanced colorectal cancer patients. Int J Cancer 121:1066–1071. doi:10.1002/ijc.22799
-
(2007)
Int J Cancer
, vol.121
, pp. 1066-1071
-
-
Maurel, J.1
Nadal, C.2
Garcia-Albeniz, X.3
Gallego, R.4
Carcereny, E.5
Almendro, V.6
Mármol, M.7
Gallardo, E.8
Maria Augé, J.9
Longarón, R.10
Martínez-Fernandez, A.11
Molina, R.12
Castells, A.13
Gascón, P.14
-
19
-
-
33947236886
-
Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway
-
COI: 1:CAS:528:DC%2BD2sXhvF2htrk%3D
-
Mhaidat NM, Zhang XD, Jiang CC, Hersey P (2007) Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway. Clin Cancer Res 13:1308–1314. doi:10.1158/1078-0432.CCR-06-2216
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1308-1314
-
-
Mhaidat, N.M.1
Zhang, X.D.2
Jiang, C.C.3
Hersey, P.4
-
20
-
-
38049130514
-
Melanoma cell sensitivity to Docetaxel-induced apoptosis is determined by class III beta-tubulin levels
-
COI: 1:CAS:528:DC%2BD1cXpsF2ntA%3D%3D
-
Mhaidat NM, Thorne RF, de Bock CE, Zhang XD, Hersey P (2008) Melanoma cell sensitivity to Docetaxel-induced apoptosis is determined by class III beta-tubulin levels. FEBS Lett 582:267–272. doi:10.1016/j.febslet.2007.12.014
-
(2008)
FEBS Lett
, vol.582
, pp. 267-272
-
-
Mhaidat, N.M.1
Thorne, R.F.2
de Bock, C.E.3
Zhang, X.D.4
Hersey, P.5
-
21
-
-
84861813700
-
Altholactone induces apoptotic cell death in human colorectal cancer cells
-
COI: 1:CAS:528:DC%2BC38XnvFOgtrc%3D
-
Mhaidat NM, Abdul-Razzak KK, Alkofahi AS, Alsarhan AM, Aldaher AN, Thorne RF (2012) Altholactone induces apoptotic cell death in human colorectal cancer cells. Phytother Res 26:926–931. doi:10.1002/ptr.3666
-
(2012)
Phytother Res
, vol.26
, pp. 926-931
-
-
Mhaidat, N.M.1
Abdul-Razzak, K.K.2
Alkofahi, A.S.3
Alsarhan, A.M.4
Aldaher, A.N.5
Thorne, R.F.6
-
22
-
-
84893006132
-
Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia
-
COI: 1:CAS:528:DC%2BC2cXntlKktr4%3D
-
Pi L, Li X, Song Q, Shen Y, Lu X, Di B (2014) Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia. Oncol Lett 7:685–692. doi:10.3892/ol.2013.1753
-
(2014)
Oncol Lett
, vol.7
, pp. 685-692
-
-
Pi, L.1
Li, X.2
Song, Q.3
Shen, Y.4
Lu, X.5
Di, B.6
-
23
-
-
35448967382
-
The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas
-
COI: 1:CAS:528:DC%2BD2sXhtFOnsb3P
-
Pyrko P, Schonthal AH, Hofman FM, Chen TC, Lee AS (2007) The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res 67:9809–9816. doi:10.1158/0008-5472.CAN-07-0625
-
(2007)
Cancer Res
, vol.67
, pp. 9809-9816
-
-
Pyrko, P.1
Schonthal, A.H.2
Hofman, F.M.3
Chen, T.C.4
Lee, A.S.5
-
24
-
-
0038080911
-
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation
-
COI: 1:CAS:528:DC%2BD3sXkt1Wisb8%3D
-
Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, Lee AS (2003) Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. J Biol Chem 278:20915–20924. doi:10.1074/jbc.M212328200
-
(2003)
J Biol Chem
, vol.278
, pp. 20915-20924
-
-
Reddy, R.K.1
Mao, C.2
Baumeister, P.3
Austin, R.C.4
Kaufman, R.J.5
Lee, A.S.6
-
25
-
-
35348827324
-
That which does not kill me makes me stronger: adapting to chronic ER stress
-
COI: 1:CAS:528:DC%2BD2sXhtF2lsbrK
-
Rutkowski DT, Kaufman RJ (2007) That which does not kill me makes me stronger: adapting to chronic ER stress. Trends Biochem Sci 32:469–476. doi:10.1016/j.tibs.2007.09.003
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 469-476
-
-
Rutkowski, D.T.1
Kaufman, R.J.2
-
26
-
-
33751069967
-
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
-
Rutkowski DT, Arnold SM, Miller CN, Wu J, Li J, Gunnison KM, Mori K, Sadighi Akha AA, Raden D, Kaufman RJ (2006) Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol 4:e374. doi:10.1371/journal.pbio.0040374
-
(2006)
PLoS Biol
, vol.e374
, pp. 4
-
-
Rutkowski, D.T.1
Arnold, S.M.2
Miller, C.N.3
Wu, J.4
Li, J.5
Gunnison, K.M.6
Mori, K.7
Sadighi Akha, A.A.8
Raden, D.9
Kaufman, R.J.10
-
27
-
-
22244446505
-
The mammalian unfolded protein response
-
Schroder M, Kaufman RJ (2005) The mammalian unfolded protein response. Annu Rev Biochem 74:739–789. doi:10.1146/annurev.biochem.73.011303.074134
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
28
-
-
84881106311
-
A specific expression profile of heat-shock proteins and glucose-regulated proteins is associated with response to neoadjuvant chemotherapy in oesophageal adenocarcinomas
-
Slotta-Huspenina J, Wolff C, Drecoll E, Feith M, Bettstetter M, Malinowsky K, Bauer L, Becker K, Ott K, Höfler H, Becker KF, Langer R (2013) A specific expression profile of heat-shock proteins and glucose-regulated proteins is associated with response to neoadjuvant chemotherapy in oesophageal adenocarcinomas. Br J Cancer 109:370–378. doi:10.1038/bjc.2013.319
-
(2013)
Br J Cancer
, vol.109
, pp. 370-378
-
-
Slotta-Huspenina, J.1
Wolff, C.2
Drecoll, E.3
Feith, M.4
Bettstetter, M.5
Malinowsky, K.6
Bauer, L.7
Becker, K.8
Ott, K.9
Höfler, H.10
Becker, K.F.11
Langer, R.12
-
29
-
-
84863134363
-
Clinical appearance of liver metastases from colorectal cancer
-
Takahashi K, Yamaguchi T, Matsumoto H, Nakano D, Watanabe F (2011) Clinical appearance of liver metastases from colorectal cancer. Nihon Rinsho 69(Suppl 3):162–165
-
(2011)
Nihon Rinsho
, vol.69
, pp. 162-165
-
-
Takahashi, K.1
Yamaguchi, T.2
Matsumoto, H.3
Nakano, D.4
Watanabe, F.5
-
30
-
-
80855128127
-
Glucose regulated protein 78 (GRP78) is overexpressed in colorectal carcinoma and regulates colorectal carcinoma cell growth and apoptosis
-
COI: 1:CAS:528:DC%2BC3MXhsVSqtr3L
-
Xing X, Li Y, Liu H, Wang L, Sun L (2011) Glucose regulated protein 78 (GRP78) is overexpressed in colorectal carcinoma and regulates colorectal carcinoma cell growth and apoptosis. Acta Histochem 113:777–782. doi:10.1016/j.acthis.2010.11.006
-
(2011)
Acta Histochem
, vol.113
, pp. 777-782
-
-
Xing, X.1
Li, Y.2
Liu, H.3
Wang, L.4
Sun, L.5
-
31
-
-
84896030993
-
Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer
-
Yang L, Yang S, Liu J, Wang X, Ji J, Cao Y, Lu K, Wang J, Gao Y (2014) Expression of GRP78 predicts taxane-based therapeutic resistance and recurrence of human gastric cancer. Exp Mol Pathol 96:235–241. doi:10.1016/j.yexmp.2014.02.011
-
(2014)
Exp Mol Pathol
, vol.96
, pp. 235-241
-
-
Yang, L.1
Yang, S.2
Liu, J.3
Wang, X.4
Ji, J.5
Cao, Y.6
Lu, K.7
Wang, J.8
Gao, Y.9
-
32
-
-
2942755868
-
Signaling the unfolded protein response from the endoplasmic reticulum
-
COI: 1:CAS:528:DC%2BD2cXkvVWhtb8%3D
-
Zhang K, Kaufman RJ (2004) Signaling the unfolded protein response from the endoplasmic reticulum. J Biol Chem 279:25935–25938. doi:10.1074/jbc.R400008200
-
(2004)
J Biol Chem
, vol.279
, pp. 25935-25938
-
-
Zhang, K.1
Kaufman, R.J.2
-
33
-
-
84893205768
-
Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3 K and enhances PI(3,4,5)P3 production
-
COI: 1:CAS:528:DC%2BC3sXhsl2jtLrF
-
Zhang Y, Tseng CC, Tsai YL, Fu X, Schiff R, Lee AS (2013) Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3 K and enhances PI(3,4,5)P3 production. PLoS One 8:e80071. doi:10.1371/journal.pone.0080071
-
(2013)
PLoS One
, vol.8
, pp. e80071
-
-
Zhang, Y.1
Tseng, C.C.2
Tsai, Y.L.3
Fu, X.4
Schiff, R.5
Lee, A.S.6
|