The antitumor natural compound falcarindiol promotes cancer cell death by inducing endoplasmic reticulum stress

Cell Death and Disease

Volumn 3, Issue 8, 2012, Pages

  Jin, H R ^a   Zhao, J ^a   Zhang, Z ^b,c   Liao, Y ^a   Wang, C Z ^b,c   Huang, W H ^d   Li, S P ^d   He, T C ^c   Yuan, C S ^b,c   Du, W ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d University of Macau   (Macao)

Author keywords

Apoptosis; ER stress; Falcarindiol; Proteasome; Unfolded protein response

Indexed keywords

CHAPERONE; FALCARINDIOL; FLUOROURACIL; GLUCOSE REGULATED PROTEIN 78; PROTEASOME; ALKYNE DERIVATIVE; ANTINEOPLASTIC AGENT; FATTY ALCOHOL; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CELL DEATH; COLON CANCER; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UNFOLDED PROTEIN RESPONSE; XENOGRAFT; ANIMAL; CELL STRAIN HCT116; COLORECTAL TUMOR; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; GENETICS; METABOLISM; TUMOR CELL LINE; UBIQUITINATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DIYNES; DRUG SYNERGISM; ENDOPLASMIC RETICULUM STRESS; FATTY ALCOHOLS; FLUOROURACIL; HCT116 CELLS; HEAT-SHOCK PROTEINS; HUMANS; MICE; TRANSPLANTATION, HETEROLOGOUS; UBIQUITINATION; UNFOLDED PROTEIN RESPONSE;

EID: 84865722080     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.122     Document Type: Article

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