메뉴 건너뛰기




Volumn 7, Issue 3, 2014, Pages 685-692

Knockdown of glucose-regulated protein 78 abrogates chemoresistance of hypopharyngeal carcinoma cells to cisplatin induced by unfolded protein in response to severe hypoxia

Author keywords

Chemoresistance; Glucose regulated protein 78; Hypopharyngeal neoplasms; Hypoxia; Unfolded protein response

Indexed keywords

CISPLATIN; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PROTEIN BAX; PROTEIN BCL 2;

EID: 84893006132     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2013.1753     Document Type: Article
Times cited : (29)

References (22)
  • 1
    • 33646338594 scopus 로고    scopus 로고
    • Clinicopathologic significance of CD105 expression in squamous cell carcinoma of the hypopharynx
    • Chien CY, Su CY, Hwang CF, Chuang HC, Hsiao YC, Wu SL and Huang CC: Clinicopathologic significance of CD105 expression in squamous cell carcinoma of the hypopharynx. Head Neck28: 441-446, 2006.
    • (2006) Head Neck , vol.28 , pp. 441-446
    • Chien, C.Y.1    Su, C.Y.2    Hwang, C.F.3    Chuang, H.C.4    Hsiao, Y.C.5    Wu, S.L.6    Huang, C.C.7
  • 2
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown JM and Wilson WR: Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer4: 437-447, 2004.
    • (2004) Nat Rev Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 3
    • 54549089738 scopus 로고    scopus 로고
    • Hypoxia signalling through mTOR and the unfolded protein response in cancer
    • Wouters BG and Koritzinsky M: Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer8: 851-864, 2008.
    • (2008) Nat Rev Cancer , vol.8 , pp. 851-864
    • Wouters, B.G.1    Koritzinsky, M.2
  • 5
    • 77955467319 scopus 로고    scopus 로고
    • Regulation of autophagy by ATF4 in response to severe hypoxia
    • Rzymski T, Milani M, Pike L, et al: Regulation of autophagy by ATF4 in response to severe hypoxia. Oncogene29: 4424-4435, 2010.
    • (2010) Oncogene , vol.29 , pp. 4424-4435
    • Rzymski, T.1    Milani, M.2    Pike, L.3
  • 6
    • 33746886623 scopus 로고    scopus 로고
    • 'Translating' tumor hypoxia: Unfolded protein response (UPR)-dependent and UPR-independent pathways
    • Koumenis C and Wouters BG: 'Translating' tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways. Mol Cancer Res4: 423-436, 2006.
    • (2006) Mol Cancer Res , vol.4 , pp. 423-436
    • Koumenis, C.1    Wouters, B.G.2
  • 7
    • 0347285295 scopus 로고    scopus 로고
    • A trip to the ER: Coping with stress
    • Rutkowski DT and Kaufman RJ: A trip to the ER: coping with stress. Trends Cell Bio14: 20-28, 2004.
    • (2004) Trends Cell Bio , vol.14 , pp. 20-28
    • Rutkowski, D.T.1    Kaufman, R.J.2
  • 8
    • 84877588873 scopus 로고    scopus 로고
    • IGFBP-3 binds GRP78, stimulates autophagy and promotes the survival of breast cancer cells exposed to adverse microenvironments
    • Grkovic S, O'Reilly VC, Han S, Hong M, Baxter RC and FirthSM: IGFBP-3 binds GRP78, stimulates autophagy and promotes the survival of breast cancer cells exposed to adverse microenvironments. Oncogene32: 2412-2420, 2012.
    • (2012) Oncogene , vol.32 , pp. 2412-2420
    • Grkovic, S.1    O'Reilly, V.C.2    Han, S.3    Hong, M.4    Baxter, R.C.5    Firth, S.M.6
  • 9
    • 84865204083 scopus 로고    scopus 로고
    • Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK
    • Kandala PK and Srivastava SK: Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK. Oncotarget3: 435-449, 2012.
    • (2012) Oncotarget , vol.3 , pp. 435-449
    • Kandala, P.K.1    Srivastava, S.K.2
  • 10
    • 79251500991 scopus 로고    scopus 로고
    • Modulation of the unfolded protein response by GRP78 in prostate cancer
    • de Ridder G, Ray R, Misra UK and Pizzo SV: Modulation of the unfolded protein response by GRP78 in prostate cancer. Methods Enzymol489: 245-257, 2011.
    • (2011) Methods Enzymol , vol.489 , pp. 245-257
    • de Ridder, G.1    Ray, R.2    Misra, U.K.3    Pizzo, S.V.4
  • 12
    • 79952312086 scopus 로고    scopus 로고
    • Cancer stem cells may be mostly maintained by fluctuating hypoxia
    • Sun Q, Li X, Lu X and Di B: Cancer stem cells may be mostly maintained by fluctuating hypoxia. Med Hypotheses76: 471-473, 2011.
    • (2011) Med Hypotheses , vol.76 , pp. 471-473
    • Sun, Q.1    Li, X.2    Lu, X.3    Di, B.4
  • 13
    • 84862834833 scopus 로고    scopus 로고
    • Overexpression of GRP78 is associated with malignant transformation in epithelial ovarian tumors
    • Huang LW, Lin CY, Lee CC, Liu TZ and Jeng CJ: Overexpression of GRP78 is associated with malignant transformation in epithelial ovarian tumors. Appl Immunohistochem Mol Morphol20: 381-385, 2012.
    • (2012) Appl Immunohistochem Mol Morphol , vol.20 , pp. 381-385
    • Huang, L.W.1    Lin, C.Y.2    Lee, C.C.3    Liu, T.Z.4    Jeng, C.J.5
  • 14
    • 84355166534 scopus 로고    scopus 로고
    • Glucose-regulated protein 78 positivity as a predictor of poor survival in patients with renal cell carcinoma
    • Kuroda K, Horiguchi A, Asano T, et al: Glucose-regulated protein 78 positivity as a predictor of poor survival in patients with renal cell carcinoma. Urol Int87: 450-456, 2011.
    • (2011) Urol Int , vol.87 , pp. 450-456
    • Kuroda, K.1    Horiguchi, A.2    Asano, T.3
  • 16
    • 84871976930 scopus 로고    scopus 로고
    • Activation of the unfolded protein response during anoxia exposure in the turtle Trachemys scripta elegans
    • Krivoruchko A and Storey KB: Activation of the unfolded protein response during anoxia exposure in the turtle Trachemys scripta elegans. Mol Cell Biochem374: 91-103, 2013.
    • (2013) Mol Cell Biochem , vol.374 , pp. 91-103
    • Krivoruchko, A.1    Storey, K.B.2
  • 17
    • 35448967382 scopus 로고    scopus 로고
    • The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas
    • Pyrko P, Schönthal AH, Hofman FM, Chen TC and Lee AS: The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res67: 9809-9816, 2007.
    • (2007) Cancer Res , vol.67 , pp. 9809-9816
    • Pyrko, P.1    Schönthal, A.H.2    Hofman, F.M.3    Chen, T.C.4    Lee, A.S.5
  • 19
    • 34248549003 scopus 로고    scopus 로고
    • GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis
    • Fu Y, Li J and Lee AS: GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis. Cancer Res67: 3734-3740, 2007.
    • (2007) Cancer Res , vol.67 , pp. 3734-3740
    • Fu, Y.1    Li, J.2    Lee, A.S.3
  • 20
    • 79960400840 scopus 로고    scopus 로고
    • Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): Endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK)
    • Zhou H, Zhang Y, Fu Y, Chan L and Lee AS: Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK). J Biol Chem286: 25687-25696, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 25687-25696
    • Zhou, H.1    Zhang, Y.2    Fu, Y.3    Chan, L.4    Lee, A.S.5
  • 21
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, Aw TY and HolbrookNJ: Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol21: 1249-1259, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 22
    • 39049160268 scopus 로고    scopus 로고
    • Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development
    • Dong D, Ni M, Li J, et al: Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Res68: 498-505, 2008.
    • (2008) Cancer Res , vol.68 , pp. 498-505
    • Dong, D.1    Ni, M.2    Li, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.