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Volumn 30, Issue 8, 2014, Pages 767-776

Profound defects in β-cell function in screen-detected type 2 diabetes are not improved with glucose-lowering treatment in the Early Diabetes Intervention Program (EDIP)

Author keywords

Acarbose; Hyperglycaemic clamp; Insulin; Obesity; Oral glucose tolerance test

Indexed keywords

ACARBOSE; GLUCOSE; INSULIN; PLACEBO; GLYCOSIDASE INHIBITOR;

EID: 84910600265     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.2553     Document Type: Article
Times cited : (9)

References (26)
  • 1
    • 0037283601 scopus 로고    scopus 로고
    • The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes
    • Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 2003; 46(1): 3-19.
    • (2003) Diabetologia , vol.46 , Issue.1 , pp. 3-19
    • Kahn, S.E.1
  • 2
    • 33745863033 scopus 로고    scopus 로고
    • Islet beta cell failure in type 2 diabetes
    • Prentki M, Nolan CJ. Islet beta cell failure in type 2 diabetes. J Clin Invest 2006; 116(7): 1802-1812.
    • (2006) J Clin Invest , vol.116 , Issue.7 , pp. 1802-1812
    • Prentki, M.1    Nolan, C.J.2
  • 3
    • 33845286208 scopus 로고    scopus 로고
    • Treating postprandial hyperglycemia does not appear to delay progression of early type 2 diabetes: the early diabetes intervention program
    • Kirkman MS, Shankar RR, Shankar S, et al. Treating postprandial hyperglycemia does not appear to delay progression of early type 2 diabetes: the early diabetes intervention program. Diabetes Care 2006; 29(9): 2095-2101.
    • (2006) Diabetes Care , vol.29 , Issue.9 , pp. 2095-2101
    • Kirkman, M.S.1    Shankar, R.R.2    Shankar, S.3
  • 4
    • 60849095141 scopus 로고    scopus 로고
    • A study of the effects of acarbose on glucose metabolism in patients predisposed to developing diabetes: the Dutch acarbose intervention study in persons with impaired glucose tolerance (DAISI)
    • Nijpels G, Boorsma W, Dekker JM, Kostense PJ, Bouter LM, Heine RJ. A study of the effects of acarbose on glucose metabolism in patients predisposed to developing diabetes: the Dutch acarbose intervention study in persons with impaired glucose tolerance (DAISI). Diabetes Metab Res Rev 2008; 24(8): 611-616.
    • (2008) Diabetes Metab Res Rev , vol.24 , Issue.8 , pp. 611-616
    • Nijpels, G.1    Boorsma, W.2    Dekker, J.M.3    Kostense, P.J.4    Bouter, L.M.5    Heine, R.J.6
  • 5
    • 0018520840 scopus 로고
    • Glucose clamp technique: a method for quantifying insulin secretion and resistance
    • DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237(3): E214-E223.
    • (1979) Am J Physiol , vol.237 , Issue.3 , pp. E214-E223
    • DeFronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 6
    • 0024216145 scopus 로고
    • Islet dysfunction in non-insulin-dependent diabetes mellitus
    • Kahn SE, Porte D Jr. Islet dysfunction in non-insulin-dependent diabetes mellitus. Am J Med 1988; 85(5A): 4-8.
    • (1988) Am J Med , vol.85 A , Issue.5 , pp. 4-8
    • Kahn, S.E.1    Porte Jr, D.2
  • 7
    • 0026666403 scopus 로고
    • Simultaneous assessment of insulin secretion and insulin sensitivity using a hyperglycemia clamp
    • Mitrakou A, Vuorinen-Markkola H, Raptis G, et al. Simultaneous assessment of insulin secretion and insulin sensitivity using a hyperglycemia clamp. J Clin Endocrinol Metab 1992; 75(2): 379-382.
    • (1992) J Clin Endocrinol Metab , vol.75 , Issue.2 , pp. 379-382
    • Mitrakou, A.1    Vuorinen-Markkola, H.2    Raptis, G.3
  • 8
    • 79951716917 scopus 로고    scopus 로고
    • From pre-diabetes to type 2 diabetes in obese youth: pathophysiological characteristics along the spectrum of glucose dysregulation
    • Bacha F, Lee S, Gungor N, Arslanian SA. From pre-diabetes to type 2 diabetes in obese youth: pathophysiological characteristics along the spectrum of glucose dysregulation. Diabetes Care 2010; 33(10): 2225-2231.
    • (2010) Diabetes Care , vol.33 , Issue.10 , pp. 2225-2231
    • Bacha, F.1    Lee, S.2    Gungor, N.3    Arslanian, S.A.4
  • 9
    • 0033960006 scopus 로고    scopus 로고
    • Reduced beta-cell compensation to the insulin resistance associated with obesity in members of Caucasian familial type 2 diabetic kindreds
    • Elbein SC, Wegner K, Kahn SE. Reduced beta-cell compensation to the insulin resistance associated with obesity in members of Caucasian familial type 2 diabetic kindreds. Diabetes Care 2000; 23(2): 221-227.
    • (2000) Diabetes Care , vol.23 , Issue.2 , pp. 221-227
    • Elbein, S.C.1    Wegner, K.2    Kahn, S.E.3
  • 10
    • 0035216023 scopus 로고    scopus 로고
    • Importance of early phase insulin secretion to intravenous glucose tolerance in subjects with type 2 diabetes mellitus
    • Kahn SE, Montgomery B, Howell W, et al. Importance of early phase insulin secretion to intravenous glucose tolerance in subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab 2001; 86(12): 5824-5829.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.12 , pp. 5824-5829
    • Kahn, S.E.1    Montgomery, B.2    Howell, W.3
  • 11
    • 84857422984 scopus 로고    scopus 로고
    • Evidence for early defects in insulin sensitivity and secretion before the onset of glucose dysregulation in obese youths: a longitudinal study
    • Giannini C, Weiss R, Cali A, et al. Evidence for early defects in insulin sensitivity and secretion before the onset of glucose dysregulation in obese youths: a longitudinal study. Diabetes 2012; 61(3): 606-614.
    • (2012) Diabetes , vol.61 , Issue.3 , pp. 606-614
    • Giannini, C.1    Weiss, R.2    Cali, A.3
  • 12
    • 79956204186 scopus 로고    scopus 로고
    • The relationship between {beta}-cell function and glycated hemoglobin: results from the veterans administration genetic epidemiology study
    • Kanat M, Winnier D, Norton L, et al. The relationship between {beta}-cell function and glycated hemoglobin: results from the veterans administration genetic epidemiology study. Diabetes Care 2011; 34(4): 1006-1010.
    • (2011) Diabetes Care , vol.34 , Issue.4 , pp. 1006-1010
    • Kanat, M.1    Winnier, D.2    Norton, L.3
  • 13
    • 67649111182 scopus 로고    scopus 로고
    • Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study
    • Tabak AG, Jokela M, Akbaraly TN, Brunner EJ, Kivimaki M, Witte DR. Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study. Lancet 2009; 373(9682): 2215-2221.
    • (2009) Lancet , vol.373 , Issue.9682 , pp. 2215-2221
    • Tabak, A.G.1    Jokela, M.2    Akbaraly, T.N.3    Brunner, E.J.4    Kivimaki, M.5    Witte, D.R.6
  • 14
    • 35649024167 scopus 로고    scopus 로고
    • Annual incidence and relative risk of diabetes in people with various categories of dysglycemia: a systematic overview and meta-analysis of prospective studies
    • Gerstein HC, Santaguida P, Raina P, et al. Annual incidence and relative risk of diabetes in people with various categories of dysglycemia: a systematic overview and meta-analysis of prospective studies. Diabetes Res Clin Pract 2007; 78(3): 305-312.
    • (2007) Diabetes Res Clin Pract , vol.78 , Issue.3 , pp. 305-312
    • Gerstein, H.C.1    Santaguida, P.2    Raina, P.3
  • 15
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346(6): 393-403.
    • (2002) N Engl J Med , vol.346 , Issue.6 , pp. 393-403
    • Knowler, W.C.1    Barrett-Connor, E.2    Fowler, S.E.3
  • 16
    • 84874826222 scopus 로고    scopus 로고
    • Pathogenesis of prediabetes: role of the liver in isolated fasting hyperglycemia and combined fasting and postprandial hyperglycemia
    • Basu R, Barosa C, Jones J, et al. Pathogenesis of prediabetes: role of the liver in isolated fasting hyperglycemia and combined fasting and postprandial hyperglycemia. J Clin Endocrinol Metab 2013; 98(3): E409-E417.
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.3 , pp. E409-E417
    • Basu, R.1    Barosa, C.2    Jones, J.3
  • 17
    • 33845514375 scopus 로고    scopus 로고
    • Pathogenesis of pre-diabetes: mechanisms of fasting and postprandial hyperglycemia in people with impaired fasting glucose and/or impaired glucose tolerance
    • Bock G, Dalla Man C, Campioni M, et al. Pathogenesis of pre-diabetes: mechanisms of fasting and postprandial hyperglycemia in people with impaired fasting glucose and/or impaired glucose tolerance. Diabetes 2006; 55(12): 3536-3549.
    • (2006) Diabetes , vol.55 , Issue.12 , pp. 3536-3549
    • Bock, G.1    Dalla Man, C.2    Campioni, M.3
  • 18
    • 0037097039 scopus 로고    scopus 로고
    • Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial
    • Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, Laakso M. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet 2002; 359(9323): 2072-2077.
    • (2002) Lancet , vol.359 , Issue.9323 , pp. 2072-2077
    • Chiasson, J.L.1    Josse, R.G.2    Gomis, R.3    Hanefeld, M.4    Karasik, A.5    Laakso, M.6
  • 19
    • 80054090833 scopus 로고    scopus 로고
    • Effects of exenatide on measures of beta-cell function after 3 years in metformin-treated patients with type 2 diabetes
    • Bunck MC, Corner A, Eliasson B, et al. Effects of exenatide on measures of beta-cell function after 3 years in metformin-treated patients with type 2 diabetes. Diabetes Care 2011; 34(9): 2041-2047.
    • (2011) Diabetes Care , vol.34 , Issue.9 , pp. 2041-2047
    • Bunck, M.C.1    Corner, A.2    Eliasson, B.3
  • 20
    • 84869111529 scopus 로고    scopus 로고
    • Exenatide plus metformin compared with metformin alone on beta-cell function in patients with Type 2 diabetes
    • Derosa G, Franzetti IG, Querci F, et al. Exenatide plus metformin compared with metformin alone on beta-cell function in patients with Type 2 diabetes. Diabet Med J Br Diabet Assoc 2012; 29(12): 1515-1523.
    • (2012) Diabet Med J Br Diabet Assoc , vol.29 , Issue.12 , pp. 1515-1523
    • Derosa, G.1    Franzetti, I.G.2    Querci, F.3
  • 21
    • 79959807374 scopus 로고    scopus 로고
    • Type 2 diabetes can be prevented with early pharmacological intervention
    • DeFronzo RA, Abdul-Ghani M. Type 2 diabetes can be prevented with early pharmacological intervention. Diabetes Care 2011; 34(Suppl 2): S202-S209.
    • (2011) Diabetes Care , vol.34 , pp. S202-S209
    • DeFronzo, R.A.1    Abdul-Ghani, M.2
  • 22
    • 43849105857 scopus 로고    scopus 로고
    • Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial
    • Weng J, Li Y, Xu W, et al. Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial. Lancet 2008; 371(9626): 1753-1760.
    • (2008) Lancet , vol.371 , Issue.9626 , pp. 1753-1760
    • Weng, J.1    Li, Y.2    Xu, W.3
  • 23
    • 84862857064 scopus 로고    scopus 로고
    • Beta-cell function preservation after 3.5 years of intensive diabetes therapy
    • Harrison LB, Adams-Huet B, Raskin P, Lingvay I. Beta-cell function preservation after 3.5 years of intensive diabetes therapy. Diabetes Care 2012; 35(7): 1406-1412.
    • (2012) Diabetes Care , vol.35 , Issue.7 , pp. 1406-1412
    • Harrison, L.B.1    Adams-Huet, B.2    Raskin, P.3    Lingvay, I.4
  • 24
    • 75549090118 scopus 로고    scopus 로고
    • Defining and characterizing the progression of type 2 diabetes
    • Fonseca VA. Defining and characterizing the progression of type 2 diabetes. Diabetes Care 2009; 32(Suppl 2): S151-S156.
    • (2009) Diabetes Care , vol.32 , pp. S151-S156
    • Fonseca, V.A.1
  • 25
    • 79959803070 scopus 로고    scopus 로고
    • Incretin effects on beta-cell function, replication, and mass: the human perspective
    • Garber AJ. Incretin effects on beta-cell function, replication, and mass: the human perspective. Diabetes Care 2011; 34(Suppl 2): S258-S263.
    • (2011) Diabetes Care , vol.34 , pp. S258-S263
    • Garber, A.J.1
  • 26
    • 84890171908 scopus 로고    scopus 로고
    • Acarbose compared with metformin as initial therapy in patients with newly diagnosed type 2 diabetes: an open-label, noninferiority randomised trial
    • Yang W, Liu J, Shan Z, et al. Acarbose compared with metformin as initial therapy in patients with newly diagnosed type 2 diabetes: an open-label, noninferiority randomised trial. Lancet Diabet Endocrinol 2014; 2(1):46-55.
    • (2014) Lancet Diabet Endocrinol , vol.2 , Issue.1 , pp. 46-55
    • Yang, W.1    Liu, J.2    Shan, Z.3


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