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Volumn 23, Issue 2, 2000, Pages 221-227

Reduced β-cell compensation to the insulin resistance associated with obesity in members of caucasian familial type 2 diabetic kindreds

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; TOLBUTAMIDE;

EID: 0033960006     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.23.2.221     Document Type: Article
Times cited : (96)

References (32)
  • 2
    • 0025663581 scopus 로고
    • Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents
    • Warram JH, Martin BC, Krolewski AS: Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents. Ann Intern Med 113:909-915, 1990
    • (1990) Ann Intern Med , vol.113 , pp. 909-915
    • Warram, J.H.1    Martin, B.C.2    Krolewski, A.S.3
  • 5
    • 0031016728 scopus 로고    scopus 로고
    • Familiality of physical and metabolic characteristics that predict the development of non-insulin-dependent diabetes mellitus in Pima Indians
    • Sakul H, Pratley R, Cardon L, Ravussin E, Mott D, Bogardus C: Familiality of physical and metabolic characteristics that predict the development of non-insulin-dependent diabetes mellitus in Pima Indians. Am J Hum Genet 60:651-656, 1997
    • (1997) Am J Hum Genet , vol.60 , pp. 651-656
    • Sakul, H.1    Pratley, R.2    Cardon, L.3    Ravussin, E.4    Mott, D.5    Bogardus, C.6
  • 7
    • 0033312608 scopus 로고    scopus 로고
    • Heritability of pancreatic β-cell function among nondiabetic members of Caucasian familial type 2 diabetes kindreds
    • Elbein SC, Hasstedt SJ, Wegner K, Kahn SE: Heritability of pancreatic β-cell function among nondiabetic members of Caucasian familial type 2 diabetes kindreds. J Clin Endocrinol Metab 84:1398-1403, 1999
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1398-1403
    • Elbein, S.C.1    Hasstedt, S.J.2    Wegner, K.3    Kahn, S.E.4
  • 8
    • 0029022819 scopus 로고
    • Pancreatic beta-cell dysfunction as the primary genetic lesion in NIDDM: Evidence from studies in normal glucose-tolerant individuals with a first-degree NIDDM relative
    • Pimenta W, Korytkowski M, Mitrakou A, Jenssen T, Yki-Jarvinen H, Evron W, Dailey G, Gerich J: Pancreatic beta-cell dysfunction as the primary genetic lesion in NIDDM: evidence from studies in normal glucose-tolerant individuals with a first-degree NIDDM relative. JAMA 273:1851-1861, 1993
    • (1993) JAMA , vol.273 , pp. 1851-1861
    • Pimenta, W.1    Korytkowski, M.2    Mitrakou, A.3    Jenssen, T.4    Yki-Jarvinen, H.5    Evron, W.6    Dailey, G.7    Gerich, J.8
  • 9
    • 0028837903 scopus 로고
    • Insulin secretion, insulin action, and hepatic glucose production in identical twins discordant for non-insulin-dependent diabetes mellitus
    • Vaag A, Henriksen JE, Madsbad S, Holm N, Beck-Nielsen H: Insulin secretion, insulin action, and hepatic glucose production in identical twins discordant for non-insulin-dependent diabetes mellitus. J Clin Invest 95:690-698, 1995
    • (1995) J Clin Invest , vol.95 , pp. 690-698
    • Vaag, A.1    Henriksen, J.E.2    Madsbad, S.3    Holm, N.4    Beck-Nielsen, H.5
  • 10
  • 11
    • 0019810028 scopus 로고
    • Physiologic evaluation of factors controlling glucose tolerance in man
    • Bergman RN, Phillips SP, Cobelli C: Physiologic evaluation of factors controlling glucose tolerance in man. J Clin Invest 68: 1456-1467, 1981
    • (1981) J Clin Invest , vol.68 , pp. 1456-1467
    • Bergman, R.N.1    Phillips, S.P.2    Cobelli, C.3
  • 13
    • 0026091812 scopus 로고
    • Insulin resistance in obese and nonobese man
    • Caro JF: Insulin resistance in obese and nonobese man. J Clin Endocrinol Metab 73: 691-695, 1991
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 691-695
    • Caro, J.F.1
  • 14
    • 0025350772 scopus 로고
    • Impact of obesity on insulin action in volunteers with normal glucose tolerance: Demonstration of a threshold for the adverse effect of obesity
    • Campbell PJ, Gerich JE: Impact of obesity on insulin action in volunteers with normal glucose tolerance: demonstration of a threshold for the adverse effect of obesity. J Clin Endocrinol Metab 70:1114-1118, 1990
    • (1990) J Clin Endocrinol Metab , vol.70 , pp. 1114-1118
    • Campbell, P.J.1    Gerich, J.E.2
  • 15
    • 0030884698 scopus 로고    scopus 로고
    • Insulin resistance and hypersecretion in obesity. European group for the study of insulin resistance (EGIR)
    • Ferrannim E, Natali A, Bell P, Cavallo-Perin P, Lalic N, Mingrone G: Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR). J Clin Invest 100:1166-1173, 1997
    • (1997) J Clin Invest , vol.100 , pp. 1166-1173
    • Ferrannim, E.1    Natali, A.2    Bell, P.3    Cavallo-Perin, P.4    Lalic, N.5    Mingrone, G.6
  • 16
    • 2642640421 scopus 로고    scopus 로고
    • Obesity-independent hyperinsulinemia in nondiabetic first-degree relatives of individuals with type 2 diabetes
    • Ishikawa M, Pruneda ML, Adams-Huet B, Raskin P: Obesity-independent hyperinsulinemia in nondiabetic first-degree relatives of individuals with type 2 diabetes. Diabetes 47:788-792, 1998
    • (1998) Diabetes , vol.47 , pp. 788-792
    • Ishikawa, M.1    Pruneda, M.L.2    Adams-Huet, B.3    Raskin, P.4
  • 17
    • 0022365713 scopus 로고
    • International criteria for the diagnosis of diabetes and impaired glucose tolerance
    • Harris MI, Hadden WC, Knowler WC, Bennett PH: International criteria for the diagnosis of diabetes and impaired glucose tolerance. Diabetes Care 8:562-567, 1985
    • (1985) Diabetes Care , vol.8 , pp. 562-567
    • Harris, M.I.1    Hadden, W.C.2    Knowler, W.C.3    Bennett, P.H.4
  • 19
    • 0008442916 scopus 로고    scopus 로고
    • Validation of a 25-sample tolbutamide-modified intravenous glucose tolerance test to phenotype subjects for genetic studies of NIDDM
    • Prigeon RL, Kahn SE, ADA GENNID Study Group: Validation of a 25-sample tolbutamide-modified intravenous glucose tolerance test to phenotype subjects for genetic studies of NIDDM. Diabetes 46 (Suppl. 1): 138A-138A, 1997
    • (1997) Diabetes , vol.46 , Issue.SUPPL. 1
    • Prigeon, R.L.1    Kahn, S.E.2
  • 20
    • 0022797049 scopus 로고
    • MINMOD: A computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test
    • Pacini G, Bergman RN: MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comput Methods Programs Biomed 23:113-122, 1986
    • (1986) Comput Methods Programs Biomed , vol.23 , pp. 113-122
    • Pacini, G.1    Bergman, R.N.2
  • 22
    • 0026575758 scopus 로고
    • Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin dependent diabetes mellitus
    • Vaag A, Henriksen JE, Beck Nielsen H: Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin dependent diabetes mellitus. J Clin Invest 89:782-788, 1992
    • (1992) J Clin Invest , vol.89 , pp. 782-788
    • Vaag, A.1    Henriksen, J.E.2    Nielsen, H.3
  • 24
    • 0030229676 scopus 로고    scopus 로고
    • In vivo glucose metabolism, insulin secretion, and insulin action in Europids with non-insulin dependent diabetes mellitus (NIDDM) and their first degree relatives
    • Beck Nielsen H, Henriksen JE, Alford F, Hother-Nielson O: In vivo glucose metabolism, insulin secretion, and insulin action in Europids with non-insulin dependent diabetes mellitus (NIDDM) and their first degree relatives. Diabet Med 13:S78-S84, 1996
    • (1996) Diabet Med , vol.13
    • Beck Nielsen, H.1    Henriksen, J.E.2    Alford, F.3    Hother-Nielson, O.4
  • 25
    • 0029880488 scopus 로고    scopus 로고
    • β-cell dysfunction independent of obesity and glucose intolerance in polycystic ovary syndrome
    • Dunaif A, Finegood DT: β-Cell dysfunction independent of obesity and glucose intolerance in polycystic ovary syndrome. J Clin Endocrinol Metab 81:942-947, 1996
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 942-947
    • Dunaif, A.1    Finegood, D.T.2
  • 28
    • 0030965884 scopus 로고    scopus 로고
    • Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leplm on insulin secretion
    • Emilsson V, Liu YL, Cawthorne MA, Morton NM, Davenport M: Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leplm on insulin secretion. Diabetes 46: 313-316, 1997
    • (1997) Diabetes , vol.46 , pp. 313-316
    • Emilsson, V.1    Liu, Y.L.2    Cawthorne, M.A.3    Morton, N.M.4    Davenport, M.5
  • 29
    • 0032478314 scopus 로고    scopus 로고
    • Fatty acid-induced beta cell apoptosis: A link between obesity and diabetes
    • Shimabukuro M, Zhou YT, Levi M, Unger RH: Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci U S A 95:2498-2502, 1998
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 2498-2502
    • Shimabukuro, M.1    Zhou, Y.T.2    Levi, M.3    Unger, R.H.4
  • 30
    • 0029927782 scopus 로고    scopus 로고
    • Elevated plasma glucose 2 h postchallenge predicts defects in β-cell function
    • Byrne MM, Sturis J, Sobel RJ, Polonsky KS: Elevated plasma glucose 2 h postchallenge predicts defects in β-cell function. Am J Physiol 270:E572-E579, 1996
    • (1996) Am J Physiol , vol.270
    • Byrne, M.M.1    Sturis, J.2    Sobel, R.J.3    Polonsky, K.S.4
  • 31
    • 0030762562 scopus 로고    scopus 로고
    • Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance
    • Cavaghan MK, Ehrmann DA, Byrne MM, Polonsky KS: Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance. J Clin Invest 100:530-537, 1997
    • (1997) J Clin Invest , vol.100 , pp. 530-537
    • Cavaghan, M.K.1    Ehrmann, D.A.2    Byrne, M.M.3    Polonsky, K.S.4
  • 32
    • 0030855145 scopus 로고    scopus 로고
    • Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome
    • Ehrmann DA, Schneider DJ, Sobel BE, Cavaghan MK, Imperial J, Rosenfield RL, Polonsky KS: Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome. J Clin Endocrinol Metab 82:2108-2116, 1997
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2108-2116
    • Ehrmann, D.A.1    Schneider, D.J.2    Sobel, B.E.3    Cavaghan, M.K.4    Imperial, J.5    Rosenfield, R.L.6    Polonsky, K.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.