Pseudo-infectious reporter virus particles for measuring antibody-mediated neutralization and enhancement of dengue virus infection

Methods in Molecular Biology

Volumn 1138, Issue , 2014, Pages 75-97

  Mukherjee, Swati ^a   Pierson, Theodore C ^a   Dowd, Kimberly A ^a  

^a NONE

Author keywords

Antibody neutralization; Antibody dependent enhancement (ADE); Dengue virus; Flavivirus; Replicon; Reporter virus particles (RVP)

Indexed keywords

FC RECEPTOR; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY;

ADHERENT CELL; ANTIBODY BLOOD LEVEL; ARTICLE; CELL CULTURE; DENGUE; DENGUE VIRUS; EXPRESSION VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONHUMAN; OPEN READING FRAME; PLASMID; PRIORITY JOURNAL; REPLICON; REPORTER GENE; SEROTYPE; STRUCTURAL GENE; TARGET CELL; TISSUE CULTURE; VIRION; VIRUS GENOME; VIRUS NEUTRALIZATION; VIRUS PARTICLE; CELL LINE; GENETIC COMPLEMENTATION; GENETICS; IMMUNOLOGY; METHODOLOGY; SERODIAGNOSIS; VIROLOGY; VIRUS LOAD;

DENGUE VIRUS; FLAVIVIRUS;

ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CELL LINE; DENGUE; DENGUE VIRUS; GENETIC COMPLEMENTATION TEST; HUMANS; NEUTRALIZATION TESTS; REPLICON; VIRAL LOAD; VIRION;

EID: 84910147384     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-0348-1_6     Document Type: Article

References (56)

1. Gubler DJ, Kuno G, Markoff L (2007) Flaviviruses. In: Knipe DM, Howley PM (eds) Fields virology. Lippincott-Raven, Philadelphia, pp 1154-1227
2. Monath TP (1994) Dengue: the risk to developed and developing countries. Proc Natl Acad Sci U S A 91:2395-2400
3. Halstead SB (2007) Dengue. Lancet 370: 1644-1652
4. Rico-Hesse R (1990) Molecular evolution and distribution of dengue viruses type 1 and 2 in nature. Virology 174:479-493
5. Holmes EC, Twiddy SS (2003) The origin, emergence and evolutionary genetics of dengue virus. Infect Genet Evol 3:19-28
6. Mukhopadhyay S, Kuhn RJ, Rossmann MG (2005) A structural perspective of the flavivirus life cycle. Nat Rev Microbiol 3:13-22
7. Lindenbach BD, Rice CM (2003) Molecular biology of flaviviruses. Adv Virus Res 59:23-61
8. Khromykh AA, Westaway EG (1997) Subgenomic replicons of the flavivirus Kunjin: construction and applications. J Virol 71: 1497-1505
9. Khromykh AA (2000) Replicon-based vectors of positive strand RNA viruses. Curr Opin Mol Therapeut 2:555-569
10. Hoenninger VM, Rouha H, Orlinger KK et al (2008) Analysis of the effects of alterations in the tick-borne encephalitis virus 3'-noncoding region on translation and RNA replication using reporter replicons. Virology 377:419-430
11. Chen Y-L, Yin Z, Duraiswamy J et al (2010) Inhibition of dengue virus RNA synthesis by an adenosine nucleoside. Antimicrob Agents Chemother 54(7):2932-2939
12. Suzuki R, Fayzulin R, Frolov I et al (2008) Identification of mutated cyclization sequences that permit efficient replication of West Nile virus genomes: use in safer propagation of a novel vaccine candidate. J Virol 82(14): 6942-6951
13. Liu WJ, Sedlak PL, Kondratieva N et al (2002) Complementation analysis of the flavivirus Kunjin NS3 and NS5 proteins defines the minimal regions essential for formation of a replication complex and shows a requirement of NS3 in cis for virus assembly. J Virol 76: 10766-10775
14. Khromykh AA, Meka H, Guyatt KJ et al (2001) Essential role of cyclization sequences in flavivirus RNA replication. J Virol 75: 6719-6728
15. Manzano M, Reichert ED, Polo S et al (2011) Identification of cis-acting elements in the 3 ' -untranslated region of the dengue virus type 2 RNA that modulate translation and replication. J Biol Chem 286: 22521-22534
16. Tilgner M, Deas TS, Shi P-Y (2005) The flavivirus-conserved penta-nucleotide in the 3' stem-loop of the West Nile virus genome requires a specific sequence and structure for RNA synthesis, but not for viral translation. Virology 331:375-386
17. Holden KL, Stein DA, Pierson TC et al (2006) Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure. Virology 344:439-452
18. Chang DC, Liu WJ, Anraku I et al (2008) Single-round infectious particles enhance immunogenicity of a DNA vaccine against West Nile virus. Nat Biotechnol 26:571-577
19. Harvey TJ, Anraku I, Linedale R et al (2003) Kunjin virus replicon vectors for human immunodeficiency virus vaccine development. J Virol 77:7796-7803
20. Suzuki R, Winkelmann ER, Mason PW (2009) Construction and characterization of a single-cycle chimeric flavivirus vaccine candidate that protects mice against lethal challenge with dengue virus type 2. J Virol 83(4): 1870-1880
21. Patkar CG, Larsen M, Owston M et al (2009) Identification of inhibitors of yellow fever virus replication using a replicon-based high-throughput assay. Antimicrob Agents Chemother 53:4103-4114
22. Puig-Basagoiti F, Qing M, Dong Hetal (2009) Identification and characterization of inhibitors of West Nile virus. Antiviral Res 83:71-79
23. Ishikawa T, Widman DG, Bourne N et al (2008) Construction and evaluation of a chi-meric pseudoinfectious virus vaccine to prevent Japanese encephalitis. Vaccine 26:2772-2781
24. Lo MK, Tilgner M, Shi PY (2003) Potential high-throughput assay for screening inhibitors of West Nile virus replication. J Virol 77(23): 12901-12906
25. Khromykh AA, Varnavski AN, Westaway EG (1998) Encapsidation of the flavivirus kunjin replicon RNA by using a complementation system providing Kunjin virus structural proteins in trans. J Virol 72:5967-5977
26. Pierson TC, Sánchez MD, Puffer BA et al (2006) A rapid and quantitative assay for measuring antibody-mediated neutralization of West Nile virus infection. Virology 346:53-65
27. Jones CT, Patkar CG, Kuhn RJ (2005) Construction and applications of yellow fever virus replicons. Virology 331:247-259
28. Scholle F, Girard YA, Zhao Q et al (2004) trans-Packaged West Nile virus-like particles: infectious properties in vitro and in infected mosquito vectors. J Virol 78:11605-11614
29. Puig-Basagoiti F, Deas TS, Ren P et al (2005) High-throughput assays using a luciferase-expressing replicon, virus-like particles, and full-length virus for West Nile virus drug discovery. Antimicrob Agents Chemother 49: 4980-4988
30. Ansarah-Sobrinho C, Nelson S, lost CA et al (2008) Temperature-dependent production of pseudoinfectious dengue reporter virus particles by complementation. Virology 381:67-74
31. Harvey TJ, Liu WJ, Wang XJ et al (2004) Tetracycline-inducible packaging cell line for production of flavivirus replicon particles. J Virol 78:531-538
32. Mattia K, Puffer BA, Williams KL et al (2011) Dengue reporter virus particles for measuring neutralizing antibodies against each of the four dengue serotypes. PloS One 6:e27252
33. Dowd KA, Jost CA, Durbin AP et al (2011) A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus. PLoS Pathog 7:e1002111
34. Varnavski AN, Young PR, Khromykh AA (2000) Stable high-level expression of heter-ologous genes in vitro and in vivo by noncyto-pathic DNA-based Kunjin virus replicon vectors. J Virol 74:4394-4403
35. Pierson TC, Diamond MS, Ahmed AA et al (2005) An infectious West Nile virus that expresses a GFP reporter gene. Virology 334:28-40
36. Yamshchikov V, Mishin V, Cominelli F (2001) A new strategy in design of + RNA virus infectious clones enabling their stable propagation in E. coli. Virology 281:272-280
37. Mishin VP, Cominelli F, Yamshchikov VF (2001) A "minimal" approach in design of flavivirus infectious DNA. Virus Res 81: 113-123
38. Varnavski AN, Khromykh AA (1999) Noncytopathic flavivirus replicon RNA-based system for expression and delivery of heterolo-gous genes. Virology 255:366-375
39. Davis CW, Nguyen H-Y, Hanna SL et al (2006) West Nile virus discriminates between DC-SIGN and DC-SIGNR for cellular attachment and infection. J Virol 80:1290-1301
40. Qing M, Liu W, Yuan Z et al (2010) A high-throughput assay using dengue-1 virus-like particles for drug discovery. Antiviral Res 86:163-171
41. Sukupolvi-Petty S, Austin SK, Engle M et al (2010) Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2. J Virol 84:9227-9239
42. Nelson S, Poddar S, Lin T-Y et al (2009) Protonation of individual histidine residues is not required for the pH-dependent entry of west nile virus: evaluation of the "histidine switch" hypothesis. J Virol 83:12631-12635
43. Nelson S, Jost CA, Xu Q et al (2008) Maturation of West Nile virus modulates sensitivity to antibody-mediated neutralization. PLoS Pathog 4:e1000060
44. Pierson TC, Diamond MS (2012) Degrees of maturity: the complex structure and biology of flaviviruses. Curr Opin Virol 2:168-175
45. Kuhn RJ, Zhang W, Rossmann MG et al (2002) Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell 108:717-725
46. Yu IM, Zhang W, Holdaway HA et al (2008) Structure of the immature dengue virus at low pH primes proteolytic maturation. Science 319:1834-1837
47. Gollins SW, Porterfield JS (1986) The uncoat-ing and infectivity of the flavivirus West Nile on interaction with cells: effects of pH and ammonium chloride. J Gen Virol 67(Pt 9): 1941-1950
48. Cherrier MV, Kaufmann B, Nybakken GE et al (2009) Structural basis for the preferential recognition of immature flaviviruses by a fusionloop antibody. EMBO J 28:3269-3276
49. Lundholt BK, Scudder KM, Pagliaro L (2003) A simple technique for reducing edge effect in cell-based assays. J Biomol Screen 8: 566-570
50. Pierson TC, Xu Q, Nelson S etal (2007) The stoichiometry of antibody-mediated neutralization and enhancement of West Nile virus infection. Cell Host Microbe 1:135-145
51. Klasse PJ, Sattentau QJ (2001) Mechanisms of virus neutralization by antibody. Curr Top Microbiol Immunol 260:87-108
52. Wang P-G, Kudelko M, Lo Jet al (2009) Efficient assembly and secretion of recombinant subviral particles of the four dengue sero-types using native prM and E proteins. PloS One 4:e8325
53. Halstead SB (2003) Neutralization and antibody-dependent enhancement of dengue viruses. Adv Virus Res 60:421-467
54. Morens DM, Halstead SB, Marchette NJ (1987) Profiles of antibody-dependent enhancement of dengue virus type 2 infection. Microb Pathog 3:231-237
55. Muñoz-Jordan JL, Sánchez-Burgos GG, Laurent-Rolle M et al (2003) Inhibition of interferon signaling by dengue virus. Proc Natl Acad Sci U S A 100:14333-14338
56. Lok S-M, Kostyuchenko V, Nybakken GE et al (2008) Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nat Struct Mol Biol 15: 312-317