Performance evaluation of Sysmex XN hematology analyzer in umbilical cord blood: A comparison study with Sysmex XE-2100

Clinical Chemistry and Laboratory Medicine

Volumn 52, Issue 12, 2014, Pages 1771-1779

  Kim, Hanah ^a   Hur, Mina ^a   Choi, Sang Gyeu ^a   Moon, Hee Won ^a   Yun, Yeo Min ^a   Hwang, Han Sung ^a   Kwon, Han Sung ^a   Sohn, In Sook ^a  

^a Konkuk University School of Medicine   (South Korea)

Author keywords

cord blood; flag; performance; Sysmex XE 2100; Sysmex XN.

Indexed keywords

HEMOGLOBIN;

ARTICLE; BLAST CELL; BLOOD ANALYSIS; BLOOD CELL COUNT; COMPARATIVE STUDY; EOSINOPHIL COUNT; ERYTHROCYTE COUNT; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FEMALE; GRANULOCYTE; HEMATOLOGICAL PARAMETERS; HEMATOLOGY ANALYZER; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN TISSUE; LEUKOCYTE DIFFERENTIAL COUNT; LYMPHOCYTE; LYMPHOCYTE COUNT; MALE; MONOCYTE; NEUTROPHIL COUNT; NEWBORN; RETICULOCYTE COUNT; SENSITIVITY AND SPECIFICITY; THROMBOCYTE COUNT; UMBILICAL CORD BLOOD; ADULT; BIRTH WEIGHT; CYTOLOGY; DEVICES; EVALUATION STUDY; FETUS BLOOD; GESTATIONAL AGE; LEUKOCYTE; MIDDLE AGED; PROCEDURES; YOUNG ADULT;

ADULT; BIRTH WEIGHT; BLOOD CELL COUNT; FEMALE; FETAL BLOOD; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; LEUKOCYTES; LYMPHOCYTES; MIDDLE AGED; YOUNG ADULT;

EID: 84910127685     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2014-0392     Document Type: Article

References (28)

1. Kang SH, Kim HK, Ham CK, Lee DS, Cho HI. Comparison of four hematology analyzers, CELL-DYN Sapphire, ADVIA 120, Coulter LH 750, and Sysmex XE-2100, in terms of clinical usefulness. Int J Lab Hematol 2008;30:480-6.
2. Meintker L, Ringwald J, Rauh M, Krause SW. Comparison of automated differential blood cell counts from Abbott Sapphire, Siemens Advia 120, Beckman Coulter DxH 800, and Sysmex XE-2100 in normal and pathologic samples. Am J Clin Pathol 2013;139:641-50.
3. Tan BT, Nava AJ, George TI. Evaluation of the Beckman Coulter UniCel DxH 800, Beckman Coulter LH 780, and Abbott Diagnostics Cell-Dyn Sapphire hematology analyzers on adult specimens in a tertiary care hospital. Am J Clin Pathol 2011;135:939-51.
4. Hotton J, Broothaers J, Swaelens C, Cantinieaux B. Performance and abnormal cell flagging comparisons of three automated blood cell counters: Cell-Dyn Sapphire, DxH-800, and XN-2000. Am J Clin Pathol 2013;140:845-52.
5. Hur M, Cho JH, Kim H, Hong MH, Moon HW, Yun YM, et al. Optimization of laboratory workflow in clinical hematology laboratory with reduced manual slide review: Comparison between Sysmex XE-2100 and ABX Pentra DX120. Int J Lab Hematol 2011;33:434-40.
6. Park BG, Park CJ, Kim S, Yoon CH, Kim DH, Jang S, et al. Comparison of the Cytodiff flow cytometric leucocyte differential count system with the Sysmex XE-2100 and Beckman Coulter UniCel DxH 800. Int J Lab Hematol 2012;34:584-93.
7. Briggs C, Longair I, Kumar P, Singh D, Machin SJ. Performance evaluation of the Sysmex haematology XN modular system. J Clin Pathol 2012;65:1024-30.
8. Seo JY, Lee ST, Kim SH. Performance evaluation of the new hematology analyzer Sysmex XN-series. Int J Lab Hematol 2014. doi: 10.1111/ijlh.12254. [Epub ahead of print 12 May 2014].
9. Kim JE, Kim BR, Woo KS, Han JY. Evaluation of the leukocyte differential on a new automated flow cytometry hematology analyzer. Int J Lab Hematol 2012;34:547-50.
10. Kim MJ, Park Q, Kim MH, Shin JW, Kim HO. Comparison of the accuracy of noninvasive hemoglobin sensor (NBM-200) and portable hemoglobinometer (HemoCue) with an automated hematology analyzer (LH500) in blood donor screening. Ann Lab Med 2013;33:261-7.
11. Gac F, Thibert JB, Le Berre C, Le Priol J, Semana G, Fest T, et al. Evaluation of CytoDiff™ on cord blood WBC differential. Int J Lab Hematol 2013;35:46-54.
12. Walka MM, Sonntag J, Kage A, Dudenhausen JW, Obladen M. Complete blood counts from umbilical cords of healthy term newborns by two automated cytometers. Acta Haematol 1998; 100:167-73.
13. Kwon MJ, Nam MH, Kim SH, Lim CS, Lee CK, Cho Y, et al. Evaluation of the nucleated red blood cell count in neonates using the Beckman Coulter UniCel DxH 800 analyzer. Int J Lab Hematol 2011;33:620-8.
14. Carroll PD, Nankervis CA, Iams J, Kelleher K. Umbilical cord blood as a replacement source for admission complete blood count in premature infants. J Perinatol 2012;32:97-102.
15. Kim H, Hur M, Choi SG, Kim BH, Moon HW, Yun YM, et al. Evaluation of ABX Pentra DX 120 and Sysmex XE-2100 in umbilical cord blood. Int J Lab Hematol 2013;35:658-65.
16. Fujimoto K. Principles of measurement in hematology analyzers manufactured by Sysmex Corporation. Sysmex J Int 1999;9:31-40.
17. Tantanate C. Spurious white blood cell count from a new automated Sysmex XN hematology analyzer. Int J Lab Hematol 2014. doi: 10.1111/ijlh.12200. [Epub ahead of print 14 Mar 2014].
18. Clinical and Laboratory Standards Institute. Reference leukocyte (WBC) differential count (proportional) and evaluation of instrumental methods; approved standard, 2nd ed. Wayne, PA: CLSI, 2007.
19. McArthur JR, editor. ASH education book. Philadelphia: Hematology Am Soc Hematol Educ Program, 2000:457-74.
20. Simson E, McFadden S, Barnes P, Machin S, editors. International Society for Laboratory Hematology Consensus Guidelines. Available from: Http://www.islh.org/web/consensus-rules.php. Accessed on 20 May 2014.
21. Eilertsen H, Vøllestad NK, Hagve TA. The usefulness of blast flags on the Sysmex XE-5000 is questionable. Am J Clin Pathol 2013;139:633-40.
22. Taylor R. Interpretation of the correlation coefficient: A basic review. J Diagn Med Sonogr 1990;1:35-9.
23. Tanaka Y, Tanaka Y, Gondo K, Maruki Y, Kondo T, Asai S, et al. Performance evaluation of platelet counting by novel fluorescent dye staining in the XN-Series automated hematology analyzers. J Clin Lab Anal 2014. doi: 10.1002/jcla.21691. [Epub ahead of print 19 Mar 2014].
24. Lesesve JF, Benbih M, Lecompte T. Accurate basophils counting: Not an easy goal! Clin Lab Haematol 2005;27:143-4.
25. Amundsen EK, Henriksson CE, Holthe MR, Urdal P. Is the blood basophil count sufficiently precise, accurate, and specific?: Three automated hematology instruments and flow cytometry compared. Am J Clin Pathol 2012;137:86-92.
26. Briggs CJ, Linssen J, Longair I, Machin SJ. Improved flagging rates on the Sysmex XE-5000 compared with the XE-2100 reduce the number of manual film reviews and increase laboratory productivity. Am J Clin Pathol 2011;136:309-16.
27. Pranke P, Failace RR, Allebrandt WF, Steibel G, Schmidt F, Nardi NB. Hematologic and immunophenotypic characterization of human umbilical cord blood. Acta Haematol 2001;105:71-6.
28. Newcomb JD, Sanberg PR, Klasko SK, Willing AE. Umbilical cord blood research: Current and future perspectives. Cell Transplant 2007;16:151-8.