Anti-GITR agonist therapy intrinsically enhances CD8 T Cell responses to chronic lymphocytic choriomeningitis virus (lcmv), thereby circumventing lcmv-induced downregulation of costimulatory gitr ligand on APC

Journal of Immunology

Volumn 193, Issue 10, 2014, Pages 5033-5043

  Clouthier, Derek L ^a   Zhou, Angela C ^a   Watts, Tania H ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CYTOKINE RECEPTOR AGONIST; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR AGONIST; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR LIGAND; PROGRAMMED DEATH 1 RECEPTOR; UNCLASSIFIED DRUG; ANTIBODY; PDCD1 PROTEIN, MOUSE; TNFSF18 PROTEIN, MOUSE; TUMOR NECROSIS FACTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELLULAR IMMUNITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG TARGETING; FEMALE; IN VIVO STUDY; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MACROPHAGE; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SPLENOMEGALY; TH1 CELL; VIRUS LOAD; AGONISTS; ANIMAL; C57BL MOUSE; DENDRITIC CELL; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; IMMUNOTHERAPY; PATHOLOGY; SIGNAL TRANSDUCTION; VIROLOGY;

ANIMALS; ANTIBODIES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; FEMALE; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; IMMUNOTHERAPY; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MACROPHAGES; MICE; MICE, INBRED C57BL; PROGRAMMED CELL DEATH 1 RECEPTOR; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TUMOR NECROSIS FACTORS;

EID: 84910119679     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401002     Document Type: Article

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