Iro/IRX transcription factors negatively regulate Dpp/TGF-β pathway activity during intestinal tumorigenesis

EMBO Reports

Volumn 15, Issue 11, 2014, Pages 1210-1218

  Martorell, Òscar ^a,b   Barriga, Francisco M ^a   Merlos Suárez, Anna ^a   Attolini, Camille Stephan Otto ^a   Casanova, Jordi ^a,b   Batlle, Eduard ^a,c   Sancho, Elena ^a   Casali, Andreu ^a  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^c INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

Dpp; EGFR Ras; TGF ; Wnt

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR IRO IRX; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; DPP PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; EYE PROTEIN; HOMEODOMAIN PROTEIN; IRX3 PROTEIN, HUMAN; IRX5 PROTEIN, HUMAN; MIRR PROTEIN, DROSOPHILA;

ADENOMA; ANIMAL CELL; ARTICLE; CANCER GROWTH; CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DROSOPHILA; GENE EXPRESSION; GENE INTERACTION; GENE MUTATION; HUMAN; HUMAN CELL; INTESTINE CARCINOGENESIS; NONHUMAN; SIGNAL TRANSDUCTION; UPREGULATION; ADENOCARCINOMA; ANIMAL; CELL CULTURE; COLORECTAL TUMOR; GENETICS; INTESTINE; METABOLISM; TUMOR CELL LINE;

ADENOCARCINOMA; ANIMALS; CARCINOGENESIS; CELL LINE, TUMOR; CELLS, CULTURED; COLORECTAL NEOPLASMS; DROSOPHILA; DROSOPHILA PROTEINS; EYE PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; INTESTINES; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84910113806     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201438622     Document Type: Article

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