-
1
-
-
0032568802
-
Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development
-
Ahmed Y., Hayashi S., Levine A., Wieschaus E. Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development. Cell 1998, 93:1171-1182.
-
(1998)
Cell
, vol.93
, pp. 1171-1182
-
-
Ahmed, Y.1
Hayashi, S.2
Levine, A.3
Wieschaus, E.4
-
2
-
-
0036339813
-
Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development
-
Ahmed Y., Nouri A., Wieschaus E. Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development. Development 2002, 129:1751-1762.
-
(2002)
Development
, vol.129
, pp. 1751-1762
-
-
Ahmed, Y.1
Nouri, A.2
Wieschaus, E.3
-
3
-
-
0036389796
-
Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs
-
Akong K., Grevengoed E.E., Price M.H., McCartney B.M., Hayden M.A., DeNofrio J.C., Peifer M. Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs. Dev Biol. 2002, 250:91-100.
-
(2002)
Dev Biol.
, vol.250
, pp. 91-100
-
-
Akong, K.1
Grevengoed, E.E.2
Price, M.H.3
McCartney, B.M.4
Hayden, M.A.5
DeNofrio, J.C.6
Peifer, M.7
-
4
-
-
0036387184
-
Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations
-
Akong K., McCartney B.M., Peifer M. Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Dev. Biol. 2002, 250:71-90.
-
(2002)
Dev. Biol.
, vol.250
, pp. 71-90
-
-
Akong, K.1
McCartney, B.M.2
Peifer, M.3
-
5
-
-
34247231997
-
A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer
-
Amos-Landgraf J.M., Kwong L.N., Kendziorski C.M., Reichelderfer M., Torrealba J., Weichert J., Haag J.D., Chen K.S., Waller J.L., Gould M.N., Dove W.F. A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer. Proc. Natl. Acad. Sci. USA 2007, 104:4036-4041.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4036-4041
-
-
Amos-Landgraf, J.M.1
Kwong, L.N.2
Kendziorski, C.M.3
Reichelderfer, M.4
Torrealba, J.5
Weichert, J.6
Haag, J.D.7
Chen, K.S.8
Waller, J.L.9
Gould, M.N.10
Dove, W.F.11
-
6
-
-
0037173081
-
Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon
-
Anderson C.B., Neufeld K.L., White R.L. Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon. Proc. Natl. Acad. Sci. USA 2002, 99:8683-8688.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8683-8688
-
-
Anderson, C.B.1
Neufeld, K.L.2
White, R.L.3
-
7
-
-
0028947862
-
Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase
-
Andjelkovic M., Jones P.F., Grossniklaus U., Cron P., Schier A.F., Dick M., Bilbe G., Hemmings B.A. Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase. J. Biol. Chem. 1995, 270:4066-4075.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 4066-4075
-
-
Andjelkovic, M.1
Jones, P.F.2
Grossniklaus, U.3
Cron, P.4
Schier, A.F.5
Dick, M.6
Bilbe, G.7
Hemmings, B.A.8
-
8
-
-
0034644526
-
Linking colorectal cancer to Wnt signaling
-
Bienz M., Clevers H. Linking colorectal cancer to Wnt signaling. Cell 2000, 103:311-320.
-
(2000)
Cell
, vol.103
, pp. 311-320
-
-
Bienz, M.1
Clevers, H.2
-
9
-
-
4043170088
-
Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors
-
Bilder D. Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors. Genes Dev. 2004, 18:1909-1925.
-
(2004)
Genes Dev.
, vol.18
, pp. 1909-1925
-
-
Bilder, D.1
-
10
-
-
80755174406
-
Maintaining tissue homeostasis: dynamic control of somatic stem cell activity
-
Biteau B., Hochmuth C.E., Jasper H. Maintaining tissue homeostasis: dynamic control of somatic stem cell activity. Cell Stem Cell 2011, 9:402-411.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 402-411
-
-
Biteau, B.1
Hochmuth, C.E.2
Jasper, H.3
-
11
-
-
79955133184
-
EGF signaling regulates the proliferation of intestinal stem cells in Drosophila
-
Biteau B., Jasper H. EGF signaling regulates the proliferation of intestinal stem cells in Drosophila. Development 2011, 138:1045-1055.
-
(2011)
Development
, vol.138
, pp. 1045-1055
-
-
Biteau, B.1
Jasper, H.2
-
12
-
-
85047688110
-
Somatic mutations in familial adenomatous polyps. Nuclear translocation of beta-catenin requires more than biallelic APC inactivation
-
Blaker H., Scholten M., Sutter C., Otto H.F., Penzel R. Somatic mutations in familial adenomatous polyps. Nuclear translocation of beta-catenin requires more than biallelic APC inactivation. Am. J. Clin. Pathol. 2003, 120:418-423.
-
(2003)
Am. J. Clin. Pathol.
, vol.120
, pp. 418-423
-
-
Blaker, H.1
Scholten, M.2
Sutter, C.3
Otto, H.F.4
Penzel, R.5
-
13
-
-
0023256456
-
Prevalence of ras gene mutations in human colorectal cancers
-
Bos J.L., Fearon E.R., Hamilton S.R., Verlaan-de Vries M., van Boom J.H., van der Eb A.J., Vogelstein B. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987, 327:293-297.
-
(1987)
Nature
, vol.327
, pp. 293-297
-
-
Bos, J.L.1
Fearon, E.R.2
Hamilton, S.R.3
Verlaan-de Vries, M.4
van Boom, J.H.5
van der Eb, A.J.6
Vogelstein, B.7
-
14
-
-
0028211876
-
Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis
-
Brand A.H., Perrimon N. Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. Genes Dev. 1994, 8:629-639.
-
(1994)
Genes Dev.
, vol.8
, pp. 629-639
-
-
Brand, A.H.1
Perrimon, N.2
-
15
-
-
78650397479
-
Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection
-
Buchon N., Broderick N.A., Kuraishi T., Lemaitre B. Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol. 2010, 8:152.
-
(2010)
BMC Biol.
, vol.8
, pp. 152
-
-
Buchon, N.1
Broderick, N.A.2
Kuraishi, T.3
Lemaitre, B.4
-
16
-
-
58949101489
-
Intestinal stem cells in mammals and Drosophila
-
Casali A., Batlle E. Intestinal stem cells in mammals and Drosophila. Cell Stem Cell 2009, 4:124-127.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 124-127
-
-
Casali, A.1
Batlle, E.2
-
17
-
-
57649107878
-
Activation of wingless targets requires bipartite recognition of DNA by TCF
-
Chang M.V., Chang J.L., Gangopadhyay A., Shearer A., Cadigan K.M. Activation of wingless targets requires bipartite recognition of DNA by TCF. Curr. Biol. 2008, 18:1877-1881.
-
(2008)
Curr. Biol.
, vol.18
, pp. 1877-1881
-
-
Chang, M.V.1
Chang, J.L.2
Gangopadhyay, A.3
Shearer, A.4
Cadigan, K.M.5
-
18
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127:469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
19
-
-
70349301437
-
APC as a master regulator of intestinal homeostasis and transformation: from flies to vertebrates
-
Cordero J., Vidal M., Sansom O. APC as a master regulator of intestinal homeostasis and transformation: from flies to vertebrates. Cell Cycle 2009, 8:2926-2931.
-
(2009)
Cell Cycle
, vol.8
, pp. 2926-2931
-
-
Cordero, J.1
Vidal, M.2
Sansom, O.3
-
20
-
-
84858414020
-
Cellular metabolism and disease: what do metabolic outliers teach us?
-
DeBerardinis R.J., Thompson C.B. Cellular metabolism and disease: what do metabolic outliers teach us?. Cell 2012, 148:1132-1144.
-
(2012)
Cell
, vol.148
, pp. 1132-1144
-
-
DeBerardinis, R.J.1
Thompson, C.B.2
-
21
-
-
77953492385
-
Nuclear beta-catenin expression and Wnt signalling: in defence of the dogma
-
Fodde R., Tomlinson I. Nuclear beta-catenin expression and Wnt signalling: in defence of the dogma. J. Pathol. 2010, 221:239-241.
-
(2010)
J. Pathol.
, vol.221
, pp. 239-241
-
-
Fodde, R.1
Tomlinson, I.2
-
22
-
-
0023262990
-
Detection of high incidence of K-ras oncogenes during human colon tumorigenesis
-
Forrester K., Almoguera C., Han K., Grizzle W.E., Perucho M. Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature 1987, 327:298-303.
-
(1987)
Nature
, vol.327
, pp. 298-303
-
-
Forrester, K.1
Almoguera, C.2
Han, K.3
Grizzle, W.E.4
Perucho, M.5
-
23
-
-
0030584086
-
Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye
-
Freeman M. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 1996, 87:651-660.
-
(1996)
Cell
, vol.87
, pp. 651-660
-
-
Freeman, M.1
-
24
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J., Thliveris A., Samowitz W., Carlson M., Gelbert L., Albertsen H., Joslyn G., Stevens J., Spirio L., Robertson M., et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 1991, 66:589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
Albertsen, H.6
Joslyn, G.7
Stevens, J.8
Spirio, L.9
Robertson, M.10
-
25
-
-
0036125041
-
A Drosophila APC tumour suppressor homologue functions in cellular adhesion
-
Hamada F., Bienz M. A Drosophila APC tumour suppressor homologue functions in cellular adhesion. Nat. Cell Biol. 2002, 4:208-213.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 208-213
-
-
Hamada, F.1
Bienz, M.2
-
26
-
-
34247176773
-
Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development
-
Hayden M.A., Akong K., Peifer M. Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development. Dev. Biol. 2007, 305:358-376.
-
(2007)
Dev. Biol.
, vol.305
, pp. 358-376
-
-
Hayden, M.A.1
Akong, K.2
Peifer, M.3
-
27
-
-
33846600427
-
PTEN-deficient intestinal stem cells initiate intestinal polyposis
-
He X.C., Yin T., Grindley J.C., Tian Q., Sato T., Tao W.A., Dirisina R., Porter-Westpfahl K.S., Hembree M., Johnson T., Wiedemann L.M., Barrett T.A., Hood L., Wu H., Li L. PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat. Genet. 2007, 39:189-198.
-
(2007)
Nat. Genet.
, vol.39
, pp. 189-198
-
-
He, X.C.1
Yin, T.2
Grindley, J.C.3
Tian, Q.4
Sato, T.5
Tao, W.A.6
Dirisina, R.7
Porter-Westpfahl, K.S.8
Hembree, M.9
Johnson, T.10
Wiedemann, L.M.11
Barrett, T.A.12
Hood, L.13
Wu, H.14
Li, L.15
-
28
-
-
6944224156
-
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling
-
He X.C., Zhang J., Tong W.G., Tawfik O., Ross J., Scoville D.H., Tian Q., Zeng X., He X., Wiedemann L.M., Mishina Y., Li L. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat. Genet. 2004, 36:1117-1121.
-
(2004)
Nat. Genet.
, vol.36
, pp. 1117-1121
-
-
He, X.C.1
Zhang, J.2
Tong, W.G.3
Tawfik, O.4
Ross, J.5
Scoville, D.H.6
Tian, Q.7
Zeng, X.8
He, X.9
Wiedemann, L.M.10
Mishina, Y.11
Li, L.12
-
29
-
-
0032032657
-
Activation of the beta-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations
-
Iwao K., Nakamori S., Kameyama M., Imaoka S., Kinoshita M., Fukui T., Ishiguro S., Nakamura Y., Miyoshi Y. Activation of the beta-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations. Cancer Res. 1998, 58:1021-1026.
-
(1998)
Cancer Res.
, vol.58
, pp. 1021-1026
-
-
Iwao, K.1
Nakamori, S.2
Kameyama, M.3
Imaoka, S.4
Kinoshita, M.5
Fukui, T.6
Ishiguro, S.7
Nakamura, Y.8
Miyoshi, Y.9
-
30
-
-
33749320834
-
APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression
-
Janssen K.P., Alberici P., Fsihi H., Gaspar C., Breukel C., Franken P., Rosty C., Abal M., El Marjou F., Smits R., Louvard D., Fodde R., Robine S. APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression. Gastroenterology 2006, 131:1096-1109.
-
(2006)
Gastroenterology
, vol.131
, pp. 1096-1109
-
-
Janssen, K.P.1
Alberici, P.2
Fsihi, H.3
Gaspar, C.4
Breukel, C.5
Franken, P.6
Rosty, C.7
Abal, M.8
El Marjou, F.9
Smits, R.10
Louvard, D.11
Fodde, R.12
Robine, S.13
-
31
-
-
80455173895
-
Intestinal stem cells in the adult Drosophila midgut
-
Jiang H., Edgar B.A. Intestinal stem cells in the adult Drosophila midgut. Exp. Cell Res. 2011, 317:2780-2788.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 2780-2788
-
-
Jiang, H.1
Edgar, B.A.2
-
32
-
-
78650977190
-
EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila
-
Jiang H., Grenley M.O., Bravo M.J., Blumhagen R.Z., Edgar B.A. EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila. Cell Stem Cell 2011, 8:84-95.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 84-95
-
-
Jiang, H.1
Grenley, M.O.2
Bravo, M.J.3
Blumhagen, R.Z.4
Edgar, B.A.5
-
33
-
-
0029116143
-
Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia
-
Kinch M.S., Clark G.J., Der C.J., Burridge K. Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia. J. Cell Biol. 1995, 130:461-471.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 461-471
-
-
Kinch, M.S.1
Clark, G.J.2
Der, C.J.3
Burridge, K.4
-
34
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler K.W., Nilbert M.C., Su L.K., Vogelstein B., Bryan T.M., Levy D.B., Smith K.J., Preisinger A.C., Hedge P., McKechnie D., et al. Identification of FAP locus genes from chromosome 5q21. Science 1991, 253:661-665.
-
(1991)
Science
, vol.253
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.K.3
Vogelstein, B.4
Bryan, T.M.5
Levy, D.B.6
Smith, K.J.7
Preisinger, A.C.8
Hedge, P.9
McKechnie, D.10
-
35
-
-
0037023584
-
Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex
-
Kramps T., Peter O., Brunner E., Nellen D., Froesch B., Chatterjee S., Murone M., Zullig S., Basler K. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell 2002, 109:47-60.
-
(2002)
Cell
, vol.109
, pp. 47-60
-
-
Kramps, T.1
Peter, O.2
Brunner, E.3
Nellen, D.4
Froesch, B.5
Chatterjee, S.6
Murone, M.7
Zullig, S.8
Basler, K.9
-
36
-
-
0030040790
-
Two distinct roles for Ras in a developmentally regulated cell migration
-
Lee T., Feig L., Montell D.J. Two distinct roles for Ras in a developmentally regulated cell migration. Development 1996, 122:409-418.
-
(1996)
Development
, vol.122
, pp. 409-418
-
-
Lee, T.1
Feig, L.2
Montell, D.J.3
-
37
-
-
0035341376
-
Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development
-
Lee T., Luo L. Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development. Trends Neurosci. 2001, 24:251-254.
-
(2001)
Trends Neurosci.
, vol.24
, pp. 251-254
-
-
Lee, T.1
Luo, L.2
-
38
-
-
69549113488
-
Adenomatous polyposis coli regulates Drosophila intestinal stem cell proliferation
-
Lee W.C., Beebe K., Sudmeier L., Micchelli C.A. Adenomatous polyposis coli regulates Drosophila intestinal stem cell proliferation. Development 2009, 136:2255-2264.
-
(2009)
Development
, vol.136
, pp. 2255-2264
-
-
Lee, W.C.1
Beebe, K.2
Sudmeier, L.3
Micchelli, C.A.4
-
39
-
-
0029830237
-
The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth
-
Leevers S.J., Weinkove D., MacDougall L.K., Hafen E., Waterfield M.D. The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. EMBO J. 1996, 15:6584-6594.
-
(1996)
EMBO J.
, vol.15
, pp. 6584-6594
-
-
Leevers, S.J.1
Weinkove, D.2
MacDougall, L.K.3
Hafen, E.4
Waterfield, M.D.5
-
40
-
-
77951833362
-
Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling
-
Li X., Han Y., Xi R. Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling. Genes Dev. 2010, 24:933-946.
-
(2010)
Genes Dev.
, vol.24
, pp. 933-946
-
-
Li, X.1
Han, Y.2
Xi, R.3
-
41
-
-
54549104587
-
Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells
-
Lin G., Xu N., Xi R. Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells. Nature 2008, 455:1119-1123.
-
(2008)
Nature
, vol.455
, pp. 1119-1123
-
-
Lin, G.1
Xu, N.2
Xi, R.3
-
42
-
-
77950367306
-
Paracrine unpaired signaling through the JAK/STAT pathway controls self-renewal and lineage differentiation of Drosophila intestinal stem cells
-
Lin G., Xu N., Xi R. Paracrine unpaired signaling through the JAK/STAT pathway controls self-renewal and lineage differentiation of Drosophila intestinal stem cells. J. Mol. Cell Biol. 2010, 2:37-49.
-
(2010)
J. Mol. Cell Biol.
, vol.2
, pp. 37-49
-
-
Lin, G.1
Xu, N.2
Xi, R.3
-
43
-
-
70349324516
-
Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways
-
Luo F., Brooks D.G., Ye H., Hamoudi R., Poulogiannis G., Patek C.E., Winton D.J., Arends M.J. Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways. Int. J. Exp. Pathol. 2009, 90:558-574.
-
(2009)
Int. J. Exp. Pathol.
, vol.90
, pp. 558-574
-
-
Luo, F.1
Brooks, D.G.2
Ye, H.3
Hamoudi, R.4
Poulogiannis, G.5
Patek, C.E.6
Winton, D.J.7
Arends, M.J.8
-
44
-
-
0028086441
-
Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion
-
Luo L., Liao Y.J., Jan L.Y., Jan Y.N. Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. Genes Dev. 1994, 8:1787-1802.
-
(1994)
Genes Dev.
, vol.8
, pp. 1787-1802
-
-
Luo, L.1
Liao, Y.J.2
Jan, L.Y.3
Jan, Y.N.4
-
45
-
-
67650230896
-
Wnt/beta-catenin signaling: components, mechanisms, and diseases
-
MacDonald B.T., Tamai K., He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 2009, 17:9-26.
-
(2009)
Dev. Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
46
-
-
0034789121
-
Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin
-
McCartney B.M., McEwen D.G., Grevengoed E., Maddox P., Bejsovec A., Peifer M. Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin. Nat. Cell Biol. 2001, 3:933-938.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 933-938
-
-
McCartney, B.M.1
McEwen, D.G.2
Grevengoed, E.3
Maddox, P.4
Bejsovec, A.5
Peifer, M.6
-
47
-
-
33745919542
-
Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila
-
McCartney B.M., Price M.H., Webb R.L., Hayden M.A., Holot L.M., Zhou M., Bejsovec A., Peifer M. Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. Development 2006, 133:2407-2418.
-
(2006)
Development
, vol.133
, pp. 2407-2418
-
-
McCartney, B.M.1
Price, M.H.2
Webb, R.L.3
Hayden, M.A.4
Holot, L.M.5
Zhou, M.6
Bejsovec, A.7
Peifer, M.8
-
48
-
-
31444452338
-
Evidence that stem cells reside in the adult Drosophila midgut epithelium
-
Micchelli C.A., Perrimon N. Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature 2006, 439:475-479.
-
(2006)
Nature
, vol.439
, pp. 475-479
-
-
Micchelli, C.A.1
Perrimon, N.2
-
49
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
Morin P.J., Sparks A.B., Korinek V., Barker N., Clevers H., Vogelstein B., Kinzler K.W. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997, 275:1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
50
-
-
0032568795
-
Coordination of growth and cell division in the Drosophila wing
-
Neufeld T.P., de la Cruz A.F., Johnston L.A., Edgar B.A. Coordination of growth and cell division in the Drosophila wing. Cell 1998, 93:1183-1193.
-
(1998)
Cell
, vol.93
, pp. 1183-1193
-
-
Neufeld, T.P.1
de la Cruz, A.F.2
Johnston, L.A.3
Edgar, B.A.4
-
51
-
-
77951008504
-
Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas
-
Obrador-Hevia A., Chin S.F., Gonzalez S., Rees J., Vilardell F., Greenson J.K., Cordero D., Moreno V., Caldas C., Capella G. Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas. J. Pathol. 2010, 221:57-67.
-
(2010)
J. Pathol.
, vol.221
, pp. 57-67
-
-
Obrador-Hevia, A.1
Chin, S.F.2
Gonzalez, S.3
Rees, J.4
Vilardell, F.5
Greenson, J.K.6
Cordero, D.7
Moreno, V.8
Caldas, C.9
Capella, G.10
-
52
-
-
31444444485
-
The adult Drosophila posterior midgut is maintained by pluripotent stem cells
-
Ohlstein B., Spradling A. The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature 2006, 439:470-474.
-
(2006)
Nature
, vol.439
, pp. 470-474
-
-
Ohlstein, B.1
Spradling, A.2
-
53
-
-
0028047389
-
Wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo
-
Peifer M., Sweeton D., Casey M., Wieschaus E. wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. Development 1994, 120:369-380.
-
(1994)
Development
, vol.120
, pp. 369-380
-
-
Peifer, M.1
Sweeton, D.2
Casey, M.3
Wieschaus, E.4
-
54
-
-
65549159598
-
A two-step model for colon adenoma initiation and progression caused by APC loss
-
Phelps R.A., Chidester S., Dehghanizadeh S., Phelps J., Sandoval I.T., Rai K., Broadbent T., Sarkar S., Burt R.W., Jones D.A. A two-step model for colon adenoma initiation and progression caused by APC loss. Cell 2009, 137:623-634.
-
(2009)
Cell
, vol.137
, pp. 623-634
-
-
Phelps, R.A.1
Chidester, S.2
Dehghanizadeh, S.3
Phelps, J.4
Sandoval, I.T.5
Rai, K.6
Broadbent, T.7
Sarkar, S.8
Burt, R.W.9
Jones, D.A.10
-
55
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell S.M., Zilz N., Beazer-Barclay Y., Bryan T.M., Hamilton S.R., Thibodeau S.N., Vogelstein B., Kinzler K.W. APC mutations occur early during colorectal tumorigenesis. Nature 1992, 359:235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
Vogelstein, B.7
Kinzler, K.W.8
-
56
-
-
0037022292
-
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis
-
Roberts R.B., Min L., Washington M.K., Olsen S.J., Settle S.H., Coffey R.J., Threadgill D.W. Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis. Proc. Natl. Acad. Sci. USA 2002, 99:1521-1526.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1521-1526
-
-
Roberts, R.B.1
Min, L.2
Washington, M.K.3
Olsen, S.J.4
Settle, S.H.5
Coffey, R.J.6
Threadgill, D.W.7
-
57
-
-
33748988989
-
Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo
-
Sansom O.J., Meniel V., Wilkins J.A., Cole A.M., Oien K.A., Marsh V., Jamieson T.J., Guerra C., Ashton G.H., Barbacid M., Clarke A.R. Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo. Proc. Natl. Acad. Sci. USA 2006, 103:14122-14127.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 14122-14127
-
-
Sansom, O.J.1
Meniel, V.2
Wilkins, J.A.3
Cole, A.M.4
Oien, K.A.5
Marsh, V.6
Jamieson, T.J.7
Guerra, C.8
Ashton, G.H.9
Barbacid, M.10
Clarke, A.R.11
-
58
-
-
2942668475
-
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
-
Sansom O.J., Reed K.R., Hayes A.J., Ireland H., Brinkmann H., Newton I.P., Batlle E., Simon-Assmann P., Clevers H., Nathke I.S., Clarke A.R., Winton D.J. Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes Dev. 2004, 18:1385-1390.
-
(2004)
Genes Dev.
, vol.18
, pp. 1385-1390
-
-
Sansom, O.J.1
Reed, K.R.2
Hayes, A.J.3
Ireland, H.4
Brinkmann, H.5
Newton, I.P.6
Batlle, E.7
Simon-Assmann, P.8
Clevers, H.9
Nathke, I.S.10
Clarke, A.R.11
Winton, D.J.12
-
59
-
-
79953649222
-
The adult Drosophila gastric and stomach organs are maintained by a multipotent stem cell pool at the foregut/midgut junction in the cardia (proventriculus)
-
Singh S.R., Zeng X., Zheng Z., Hou S.X. The adult Drosophila gastric and stomach organs are maintained by a multipotent stem cell pool at the foregut/midgut junction in the cardia (proventriculus). Cell Cycle 2011, 10:1109-1120.
-
(2011)
Cell Cycle
, vol.10
, pp. 1109-1120
-
-
Singh, S.R.1
Zeng, X.2
Zheng, Z.3
Hou, S.X.4
-
60
-
-
0032521433
-
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer
-
Sparks A.B., Morin P.J., Vogelstein B., Kinzler K.W. Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res. 1998, 58:1130-1134.
-
(1998)
Cancer Res.
, vol.58
, pp. 1130-1134
-
-
Sparks, A.B.1
Morin, P.J.2
Vogelstein, B.3
Kinzler, K.W.4
-
61
-
-
80055094597
-
Quiescent gastric stem cells maintain the adult Drosophila stomach
-
Strand M., Micchelli C.A. Quiescent gastric stem cells maintain the adult Drosophila stomach. Proc. Natl. Acad. Sci. USA 2011, 108:17696-17701.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 17696-17701
-
-
Strand, M.1
Micchelli, C.A.2
-
62
-
-
48349135915
-
The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling
-
Takashima S., Mkrtchyan M., Younossi-Hartenstein A., Merriam J.R., Hartenstein V. The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling. Nature 2008, 454:651-655.
-
(2008)
Nature
, vol.454
, pp. 651-655
-
-
Takashima, S.1
Mkrtchyan, M.2
Younossi-Hartenstein, A.3
Merriam, J.R.4
Hartenstein, V.5
-
63
-
-
0033827119
-
Combinatorial chemoprevention of intestinal neoplasia
-
Torrance C.J., Jackson P.E., Montgomery E., Kinzler K.W., Vogelstein B., Wissner A., Nunes M., Frost P., Discafani C.M. Combinatorial chemoprevention of intestinal neoplasia. Nat. Med. 2000, 6:1024-1028.
-
(2000)
Nat. Med.
, vol.6
, pp. 1024-1028
-
-
Torrance, C.J.1
Jackson, P.E.2
Montgomery, E.3
Kinzler, K.W.4
Vogelstein, B.5
Wissner, A.6
Nunes, M.7
Frost, P.8
Discafani, C.M.9
-
64
-
-
0030999806
-
Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
-
van de Wetering M., Cavallo R., Dooijes D., van Beest M., van Es J., Loureiro J., Ypma A., Hursh D., Jones T., Bejsovec A., Peifer M., Mortin M., Clevers H. Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 1997, 88:789-799.
-
(1997)
Cell
, vol.88
, pp. 789-799
-
-
van de Wetering, M.1
Cavallo, R.2
Dooijes, D.3
van Beest, M.4
van Es, J.5
Loureiro, J.6
Ypma, A.7
Hursh, D.8
Jones, T.9
Bejsovec, A.10
Peifer, M.11
Mortin, M.12
Clevers, H.13
-
65
-
-
67650757497
-
A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila
-
Webb R.L., Zhou M.N., McCartney B.M. A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila. Development 2009, 136:1283-1293.
-
(2009)
Development
, vol.136
, pp. 1283-1293
-
-
Webb, R.L.1
Zhou, M.N.2
McCartney, B.M.3
-
66
-
-
0033828645
-
Mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye
-
Weber U., Paricio N., Mlodzik M. mediates Frizzled-induced R3/R4 cell fate distinction and planar polarity determination in the Drosophila eye. Development 2000, 127:3619-3629.
-
(2000)
Development
, vol.127
, pp. 3619-3629
-
-
Weber, U.1
Paricio, N.2
Mlodzik, M.3
-
67
-
-
41949105179
-
Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling
-
Wu X., Tu X., Joeng K.S., Hilton M.J., Williams D.A., Long F. Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling. Cell 2008, 133:340-353.
-
(2008)
Cell
, vol.133
, pp. 340-353
-
-
Wu, X.1
Tu, X.2
Joeng, K.S.3
Hilton, M.J.4
Williams, D.A.5
Long, F.6
-
68
-
-
79955521176
-
EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells
-
Xu N., Wang S.Q., Tan D., Gao Y., Lin G., Xi R. EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells. Dev. Biol. 2011, 354:31-43.
-
(2011)
Dev. Biol.
, vol.354
, pp. 31-43
-
-
Xu, N.1
Wang, S.Q.2
Tan, D.3
Gao, Y.4
Lin, G.5
Xi, R.6
-
69
-
-
0141483737
-
Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome
-
Yamashita Y.M., Jones D.L., Fuller M.T. Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science 2003, 301:1547-1550.
-
(2003)
Science
, vol.301
, pp. 1547-1550
-
-
Yamashita, Y.M.1
Jones, D.L.2
Fuller, M.T.3
-
70
-
-
18244389736
-
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta-catenin signaling is activated in human colon tumors
-
Yan D., Wiesmann M., Rohan M., Chan V., Jefferson A.B., Guo L., Sakamoto D., Caothien R.H., Fuller J.H., Reinhard C., Garcia P.D., Randazzo F.M., Escobedo J., Fantl W.J., Williams L.T. Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta-catenin signaling is activated in human colon tumors. Proc. Natl. Acad. Sci. USA 2001, 98:14973-14978.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14973-14978
-
-
Yan, D.1
Wiesmann, M.2
Rohan, M.3
Chan, V.4
Jefferson, A.B.5
Guo, L.6
Sakamoto, D.7
Caothien, R.H.8
Fuller, J.H.9
Reinhard, C.10
Garcia, P.D.11
Randazzo, F.M.12
Escobedo, J.13
Fantl, W.J.14
Williams, L.T.15
-
71
-
-
77649185151
-
Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II
-
Zimmerman S.G., Thorpe L.M., Medrano V.R., Mallozzi C.A., McCartney B.M. Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II. Dev. Biol. 2010, 340:54-66.
-
(2010)
Dev. Biol.
, vol.340
, pp. 54-66
-
-
Zimmerman, S.G.1
Thorpe, L.M.2
Medrano, V.R.3
Mallozzi, C.A.4
McCartney, B.M.5
|