Omics and biotechnology of arsenic stress and detoxification in plants: Current updates and prospective

Environment International

Volumn 74, Issue , 2015, Pages 221-230

  Kumar, Smita ^a,c   Dubey, Rama Shanker ^b   Tripathi, Rudra Deo ^a   Chakrabarty, Debasis ^a   Trivedi, Prabodh Kumar ^a  

^a CSIR NATIONAL BOTANICAL RESEARCH INSTITUTE   (India)

^b BANARAS HINDU UNIVERSITY   (India)

^c UNIVERSITY OF LUCKNOW   (India)

Author keywords

Arsenic; Metabolomic; Proteomic; Rice; Transcriptomic; Transgenic plants

Indexed keywords

ARSENIC; BIOTECHNOLOGY; DETOXIFICATION; FOOD PRODUCTS; GROUNDWATER; HEALTH HAZARDS; WATER POLLUTION;

METABOLOMICS; PROTEOMIC; RICE; TRANSCRIPTOMIC; TRANSGENIC PLANTS;

FOOD MICROBIOLOGY;

ANTIOXIDANT; ARSENIC; POLLUTANT; PROTEOME; TRANSCRIPTOME;

ANTHROPOGENIC SOURCE; ARSENIC; BIOACCUMULATION; BIOTECHNOLOGY; CROP PRODUCTION; DETOXIFICATION; ENVIRONMENTAL STRESS; GENOMICS; PLANT;

BIOACCUMULATION; BIOMICS; BIOTECHNOLOGY; BIOTRANSFORMATION; DETOXIFICATION; ENVIRONMENTAL STRESS; FOOD CONTAMINATION; FUNCTIONAL GENOMICS; GENE EXPRESSION; METABOLOMICS; METAL TOLERANCE; NONHUMAN; PHYTOREMEDIATION; PLANT; PLANT DEFENSE; PLANT DEVELOPMENT; PLANT GENE; PLANT GROWTH; PLANT METABOLISM; PLANT STRESS; PROTEOMICS; REVIEW; SOURCE SINK RELATIONSHIP; TRANSCRIPTOMICS; TRANSGENIC PLANT; FOOD CHAIN; GENETICS; GENOMICS; METABOLISM; METABOLOME; PHARMACOKINETICS; PHYSIOLOGICAL STRESS; POLLUTANT;

ARSENIC; BIOTECHNOLOGY; ENVIRONMENTAL POLLUTANTS; FOOD CHAIN; FOOD CONTAMINATION; GENOMICS; METABOLOME; PLANTS; PLANTS, GENETICALLY MODIFIED; PROTEOME; STRESS, PHYSIOLOGICAL; TRANSCRIPTOME;

EID: 84910066019     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2014.10.019     Document Type: Review

References (128)

1. Abercrombie J.M., Halfhill M.D., Ranjan P., Rao M.R., Saxton A.M., Yuan J.S., Stewart C.N. Transcriptional responses of Arabidopsis thaliana plants to As(V) stress. BMC Plant Biol. 2008, 8:87-96.
2. Ahsan N., Lee D.G., Alam I., Kim P.J., Lee J.J., Ahn Y.O., Kwak S.S., Lee I.J., Bahk J.D., Kang K.Y., Renaut J., Komatsu S., Lee B.H. Comparative proteomic study of arsenic induced differentially expressed proteins in rice roots reveals glutathione plays a central role during As stress. Proteomics 2008, 8:3561-3576.
3. Ahsan N., Lee D.G., Kim K.H., Alam I., Lee S.H., Lee K.W., Lee H., Lee B.H. Analysis of arsenic stress induced differentially expressed proteins in rice leaves by two-dimensional gel electrophoresis coupled with mass spectrometry. Chemosphere 2010, 78:224-231.
4. Ali W., Isner J.C., Isayenkov S.V., Liu W., Zhao F.J., Maathuis F.J.M. Heterologous expression of the yeast arsenite efflux system ACR3 improves Arabidopsis thaliana tolerance to arsenic stress. New Phytol. 2012, 194:716-723.
5. Banerjee M., Banerjee N., Bhattacharjee P., Mondal D., Lythgoe P.R., Martinez M., Pan J., Polya D.A., Giri A.K. High arsenic in rice is associated with elevated genotoxic effects in humans. Sci. Rep. 2013, 3:1-8.
6. Bleeker P.M., Hakvoort H.W.J., Bliek M., Souer E., Schat H. Enhanced arsenate reduction by a CDC25-like tyrosine phosphatase explains increased phytochelatin accumulation in arsenate-tolerant Holcus lanatus. Plant J. 2006, 45:917-929.
7. Bona E., Cattaneo C., Cesaro P., Marsano F., Lingua G., Cavaletto M., Berta G. Proteomic analysis of Pteris vittata fronds: two arbuscular mycorrhizal fungi differentially modulate protein expression under arsenic contamination. Proteomics 2010, 10:3811-3834.
8. Bondada B.R., Ma L.Q. Tolerance of heavy metals in vascular plants: arsenic hyperaccumulation by Chinese Brake fern (Pteris vittata L.). Pteridology in the New Millennium 2003, 1:397-420.
9. Borak J., Hosgood H.D. Seafood arsenic: implications for human risk assessment. Regul. Toxicol. Pharmacol. 2007, 47:204-212.
10. Carey A.M., Scheckel K.G., Lombi E., Newville M., Choi Y., Norton G.J., Charnock J.M., Feldmann J., Price A.H., Meharg A.A. Grain unloading of arsenic species in rice. Plant Physiol. 2010, 152:309-319.
11. Chakrabarty D., Trivedi P.K., Misra P., Tiwari M., Shri M., Shukla D., Kumar S., Rai A., Pandey A., Nigam D., Tripathi R.D., Tuli R. Comparative transcriptome analysis of arsenate and arsenite stresses in rice seedlings. Chemosphere 2009, 74:688-702.
12. Chen Y., Xu W., Shen H., Yan H., Xu W., He Z., Ma M. Engineering arsenic tolerance and hyperaccumulation in plants for phytoremediation by a PvACR3 transgenic approach. Environ. Sci. Technol. 2013, 47:9355-9362.
13. Choudhury B., Mitra S., Biswas A.K. Regulation of sugar metabolism in rice (Oryza sativa L.) seedlings under arsenate toxicity and its improvement by phosphate. Physiol. Mol. Biol. Plants 2010, 16:59-68.
14. Dave R., Mishra A., Tripathi R.D., Dwivedi S., Tripathi P., Dixit G., Sharma Y.K., Trivedi P.K., Corpus F.J., Barroso J.B., Chakrabarty D. Arsenate and arsenite exposure modulate antioxidants and amino acids in contrasting arsenic accumulating rice (Oryza sativa L.) genotypes. J. Hazard. Mater. 2013, 262:1123-1131.
15. Dave R., Singh P.K., Tripathi P., Shri M., Dixit G., Dwivedi S., Chakrabarty D., Trivedi P.K., Sharma Y.K., Dhankher O.P., Corpas F.J., Barroso J.B., Tripathi R.D. Arsenite tolerance is related to proportional thiolic metabolite synthesis in rice (Oryza sativa L.). Arch. Environ. Contam. Toxicol. 2013, 64:235-242.
16. Dhankher O.P., Li Y., Rosen B.P., Shi J., Salt D., Senecoff J.F., Sashti N.A., Meagher R.B. Engineering tolerance and hyperaccumulation of arsenic in plants by combining arsenate reductase and γ-glutamylcysteinesynthetase expression. Nat. Biotechnol. 2002, 20:1140-1145.
17. Dhankher O.P., Rosen B.P., McKinney E.C., Meagher R.B. Hyperaccumulation of arsenic in the shoots of Arabidopsis silenced for arsenate reductase (ACR2). Proc. Natl. Acad. Sci. U. S. A. 2005, 103:5413-5418.
18. Duan G., Kamiya T., Ishikawa S., Arao T., Fujiwara T. Expressing ScACR3 in rice enhanced arsenite efflux and reduced arsenic accumulation in rice grains. Plant Cell Physiol. 2012, 53:154-163.
19. Dubey S., Misra P., Dwivedi S., Chatterjee S., Bag S.K., Mantri S., Asif M.H., Rai A., Kumar S., Shri M., Tripathi P., Tripathi R.D., Trivedi P.K., Chakrabarty D., Tuli R. Transcriptomic and metabolomic shifts in rice roots in response to Cr(VI) stress. BMC Genomics 2010, 11:648.
20. Dubey S., Shri M., Misra P., Lakhwani D., Bag S.K., Asif M.H., Trivedi P.K., Tripathi R.D., Chakrabarty D. Heavy metals induce oxidative stress and genome-wide modulation in transcriptome of rice root. Funct. Integr. Genomics 2014, 14:401-417.
21. Duquesnoy I., Goupil P., Nadaud I., Branlard G., Piquet-Pissaloux A., Ledoigt G. Identification of Agrostis tenuis leaf proteins in response to As(V) and As(III) induced stress using a proteomics approach. Plant Sci. 2009, 176:206-213.
22. Dwivedi S., Tripathi R.D., Srivastava S., Singh R., Kumar A., Tripathi P., Dave P., Rai U.N., Chakrabarty D., Trivedi P.K., Tuli R., Adhikari B., Bag M.K. Arsenic accumulation profile effects trace nutrients in different rice (Oryza sativa L.) genotypes. Protoplasma 2010, 245:113-124.
23. Dwivedi S., Tripathi R.D., Tripathi P., Kumar A., Dave R., Mishra S., Singh R., Sharma D., Rai U., Debasis C., Trivedi P.K., Adhikari B., Bag M., Dhankher O.P., Rakesh R. Arsenate exposure affects amino acids, mineral nutrient status and antioxidants in rice (Oryza sativa L.) genotypes. Environ. Sci. Technol. 2010, 44:9542-9549.
24. Dwivedi S., Mishra A., Dave R., Kumar A., Tripathi P., Srivastava S., Chakrabarty D., Trivedi P.K., Adhikari B., Norton G., Tripathi R.D., Nautiyal C.S. Arsenic affects essential and non-essential amino acids differentially in rice grains: inadequacy of amino acids in rice based diet. Environ. Int. 2012, 46C:16-22.
25. Fayiga A.O., Ma L.Q., Santos J., Rathinasabapathi B., Stamps B., Littell R.C. Effects of arsenic species and concentrations on arsenic accumulation by different fern species in a hydroponic system. Int. J. Phytoremediation 2005, 7:230-240.
26. Francesconi K., Visoottiviseth P., Sridokchan W., Goessler W. Arsenic species in an arsenic hyperaccumulating fern, Pityrogramma calomelanos: a potential phytoremediator of arsenic-contaminated soils. Sci. Total Environ. 2002, 284:27-35.
27. Gasic K., Korban S.S. Transgenic Indian mustard (Brassica juncea) plants expressing an Arabidopsis phytochelatin synthase (AtPCS1) exhibit enhanced As and Cd tolerance. Plant Mol. Biol. 2007, 64:361-369.
28. Gautam N., Verma P.K., Verma S., Tripathi R.D., Trivedi P.K., Adhikari B., Chakrabarty D. Genome-wide identification of rice Class I metallothionein gene: tissue expression patterns and induction in response to heavy metal stress. Funct. Integr. Genomics 2012, 12:635-647.
29. Ghosh M., Shen J., Rosen B.P. Pathways of As(III) detoxification in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:5001-5006.
30. Grispen V.M.J., Irtelli B., Hakvoorta H.J., Vooijs R., Bliek B., Bookum W.M., Verkleij J.A.C., Schat H. Expression of the Arabidopsis metallothionein 2b enhances arsenite sensitivity and root to shoot translocation in tobacco. Environ. Exp. Bot. 2009, 66:69-73.
31. Gulz P.A., Gupta S.K., Schulin R. Arsenic accumulation of common plants from contaminated soils. Plant Soil 2005, 272:337-347.
32. Guo J., Dai X., Xu W., Ma M. Overexpressing GSH1 and AsPCS1 simultaneously increases the tolerance and accumulation of cadmium and arsenic in Arabidopsis thaliana. Chemosphere 2008, 72:1020-1026.
33. Gupta M., Ahmad M.A. Arsenate induced differential response in rice genotypes. Ecotoxicol. Environ. Saf. 2014, 107:46-54.
34. Huang J.H., Scherr F., Matzner E. Demethylation of dimethylarsinic acid and arsenobetaine in different organic soils. Water Air Soil Pollut. 2007, 182:31-41.
35. Huang J., Zhang Y., Peng J.S., Zhong C., Yi H.Y., Ow D.W., Gong J.M. Fission yeast HMT1 lowers seed cadmium through phytochelatin-dependent vacuolar sequestration in Arabidopsis. Plant Physiol. 2012, 158:1779-1788.
36. Indriolo E., Na G.N., Ellis D., Salt D.E., Banks J.A. A vacuolar arsenite transporter necessary for arsenic tolerance in the arsenic hyperaccumulating fern Pteris vittata is missing in flowering plants. Plant Cell 2010, 22:2045-2057.
37. Jia Y., Huang H., Chen Z., Zhu Y.G. Arsenic uptake by rice is influenced by microbe-mediated arsenic redox changes in the rhizosphere. Environ. Sci. Technol. 2014, 48:1001-1007.
38. Jin Y.H., Dunlap P.E., McBride S.J., Al-Refai H., Bushel P.R., Freedman J.H. Global transcriptome and deletome profiles of yeast exposed to transition metals. PLoS Genet. 2008, 4:1-14.
39. Kumar S., Asif M.H., Chakrabarty D., Tripathi R.D., Trivedi P.K. Differential expression and alternative splicing of rice sulphate transporter family members regulate sulphur status during plant growth, development and stress conditions. Funct. Integr. Genomics 2011, 11:259-273.
40. Kumar S., Asif M.H., Chakrabarty D., Tripathi R.D., Dubey R.S., Trivedi P.K. Differential expression of rice Lambda class GST gene family members during plant growth, development, and in response to stress conditions. Plant Mol. Biol. Report. 2013, 31:569-580.
41. Kumar S., Asif M.H., Chakrabarty D., Tripathi R.D., Dubey R.S., Trivedi P.K. Expression of a rice Lambda class of glutathione S-transferase, OsGSTL2, in Arabidopsis provides tolerance to heavy metal and other abiotic stresses. J. Hazard. Mater. 2013, 249:228-237.
42. Lam S.H., Winata C.L., Tong Y., Korzh S., Lim W.S., Korzh V., Spitsbergen J., Mathavan S., Miller L.D., Liu E.T., Gong Z. Transcriptome kinetics of arsenic-induced adaptive response in zebrafish liver. Physiol. Genomics 2006, 27:351-361.
43. Le Blanc M.S., Lima A., Montello P., Kim T., Meagher R.B., Merkle S. Enhanced arsenic tolerance of transgenic eastern cottonwood plants expressing gamma-glutamylcysteine synthetase. Int. J. Phytoremediation 2011, 13:657-673.
44. Leung H.M., Wu F.Y., Cheung K.C., Ye Z.H., Wong M.H. The effect of arbuscular mycorrhizal fungi and phosphate amendement on arsenic uptake, accumulation and growth of Pteris vittata in As-contaminated soil. Int. J. Phytoremediation 2010, 12:384-403.
45. Li Y., Dhankher O.P., Carreira L., Lee D., Chen A., Schroeder J.I., Balish R.S., Meagher R.B. Overexpression of phytochelatin synthase in Arabidopsis leads to enhanced arsenic tolerance and cadmium hypersensitivity. Plant Cell Physiol. 2004, 45:1787-1797.
46. Li Y., Dhankher O.P., Carreira L., Balish R.S., Meagher R.B. Arsenic and mercury tolerance and cadmium sensitivity in Arabidopsis plants expressing bacterial gamma-glutamylcysteinesynthetase. Environ. Toxicol. Chem. 2005, 24:1376-1386.
47. Li Y., Dhankher O.P., Carreira L., Smith A.P., Meagher R.B. The shoot-specific expression of γ-glutamylcysteine synthetase directs the long-distance transport of thiol-peptides to roots conferring tolerance to mercury and arsenic. Plant Physiol. 2006, 141:288-298.
48. Li R.Y., Ago Y., Liu W.J., Mitani N., Feldmann J., McGrath S.P., Ma J.F., Zhao F.J. The rice aquaporin Lsi1 mediates uptake of methylated arsenic species. Plant Physiol. 2009, 150:2071-2080.
49. Li H., Man Y.B., Ye Z.H., Wu S.C., Wong M.H. Do arbuscular mycorrhizal fungi affect arsenic accumulation and speciation in rice with different radial oxygen loss?. J. Hazard. Mater. 2013, 262:1098-1104.
50. Liu Q., Zhang H. Molecular identification and analysis of arsenite stress-responsive miRNAs in rice. J. Agric. Food Chem. 2012, 60:6524-6536.
51. Liu W.J., Wood B.A., Raab A., McGrath S.P., Zhao F.J., Feldmann J. Complexation of arsenite with phytochelatins reduces arsenite efflux and translocation from roots to shoots in Arabidopsis. Plant Physiol. 2010, 152:2211-2221.
52. Liu Y., Li M., Han C., Wu F., Tu B., Pingfang Y. Comparative proteomic analysis of rice shoots exposed to high arsenate. J. Integr. Plant Biol. 2013, 55:965-978.
53. Lizama A.K., Fletcher T.D., Sun G. Removal processes for arsenic in constructed wetlands. Chemosphere 2011, 84:1032-1043.
54. Logoteta B., Xu X.Y., Macnair M.R., McGrath S.P., Zhao F.J. Arsenite efflux is not enhanced in the arsenate-tolerant phenotype of Holcus lanatus. New Phytol. 2009, 183:340-348.
55. Ma L.Q., Komar K.M., Tu C., Zhang W., Cai Y., Kennelley E.D. A fern that hyperaccumulates arsenic. Nature 2001, 409:579.
56. Ma J.F., Yamaji N., Mitani N., Xu X.Y., Su Y.H., McGrath S.P., Zhao F.J. Transporters of arsenite in rice and their role in arsenic accumulation in rice grain. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:9931-9935.
57. + exchange in Saccharomyces cerevisiae. BBA Biomembr. 2011, 1808:1855-1859.
58. Meharg A.A. Variation in arsenic accumulation - hyperaccumulation in ferns and their allies. New Phytol. 2003, 157:25-31.
59. Meharg A.A., Macnair M.R. Suppression of the high-affinity phosphate-uptake system: a mechanism of arsenate tolerance in Holcus lanatus L. J. Exp. Bot. 1992, 43:519-524.
60. Meng Y.L., Liu Z., Rosen B.P. As(III) and Sb(III) uptake by GlpF and efflux by ArsB in Escherichia coli. J. Biol. Chem. 2004, 279:18334-18341.
61. Meng X.Y., Qin J., Wang L.H., Duan G.L., Sun G.X., Wu H.L., Chu C.C., Ling H.Q., Rosen B.P., Zhu Y.G. Arsenic biotransformation and volatilization in transgenic rice. New Phytol. 2011, 191:49-56.
62. Mirza N., Mahmood Q., Shah M.M., Pervez A., Sultan S. Plants as useful vectors to reduce environmental toxic arsenic content. Sci. World J. 2014, 2014:1-11.
63. Mishra S., Dubey R.S. Inhibition of ribonuclease and protease activities in arsenic exposed rice seedlings: role of proline as enzyme protectant. J. Plant Physiol. 2006, 163:927-936.
64. Mishra P., Dubey R.S. Excess nickel modulates activities of carbohydrate metabolizing enzymes and induces accumulation of sugars by upregulating acid invertase and sucrose synthase in rice seedlings. Biometals 2013, 26:97-111.
65. Mishra S., Srivastava S., Tripathi R.D., Trivedi P.K. Thiol metabolism and antioxidant systems complement each other during arsenate detoxification in Ceratophyllum demersum L. Aquat. Toxicol. 2008, 86:205-215.
66. Mishra S., Wellenreuther G., Mattusch J., Stark H.J., Kupper H. Speciation and Distribution of arsenic in the nonhyperaccumulator macrophyte Ceratophyllum demersum. Plant Physiol. 2013, 163:1396-1408.
67. Mosa K.A., Kumar K., Chhikara S., Mcdermott J., Liu Z., Musante C., White J.C., Dhankher O.P. Members of rice plasma membrane intrinsic proteins subfamily are involved in arsenite permeability and tolerance in plants. Transgenic Res. 2012, 21:1265-1277.
68. Navaza A.P., Bayon M.M., LeDuc D.L., Terry N., Sanz-Medel A. Study of phytochelatins and other related thiols as complexing biomolecules of As and Cd in wild type and genetically modified Brassica juncea plants. J. Mass Spectrom. 2006, 41:323-331.
69. Neumann R.B., Ashfaque K.N., Badruzzaman A.B.M., Ali M.A., Shoemaker J.K., Harvey C.F. Anthropogenic influences on groundwater arsenic concentrations in Bangladesh. Nat. Geosci. 2010, 3:46-52.
70. Newcombe C., Raab A., Williams P.N., Deacon C., Haris P.I., Meharg A.A., Feldmann J. Accumulation or production of arsenobetaine in humans?. J. Environ. Monit. 2010, 12:832-837.
71. Norton G.J., Lou-Hing D.E., Meharg A.A., Price A.H. Rice-arsenate interactions in hydroponics: whole genome transcriptional analysis. J. Exp. Bot. 2008, 59:2267-2276.
72. Paulose B., Kandasamy S., Dhankher O.P. Expression profiling of Crambe abyssinica under arsenate stress identifies genes and gene networks involved in arsenic metabolism and detoxification. BMC Plant Biol. 2010, 10:1-12.
73. Peryea F.J. Gardening on Lead- and Arsenic-Contaminated Soils 2001, Washington State University.
74. Pickering I.J., Prince R.C., George M.J., Smith R.D., George G.N., Salt D.E. Reduction and coordination of arsenic in Indian mustard. Plant Physiol. 2000, 122:1171-1178.
75. Poynton C.Y., Huang J.W.W., Blaylock M.J., Kochian L.V., Elless M.P. Mechanisms of arsenic hyperaccumulation in Pteris species: root As influx and translocation. Planta 2004, 219:1080-1088.
76. Prasad M.N.V., Freitas H., Fraenzle S., Wuenschmann S., Markert B. Knowledge explosion in phytotechnologies for environmental solutions. Environ. Pollut. 2010, 158:18-23.
77. Raab A., Feldmann J., Meharg A.A. The nature of arsenic-phytochelatin complexes in Holcus lanatus and Pteris cretica. Plant Physiol. 2004, 134:1113-1122.
78. Raab A., Williams P.N., Meharg A., Feldmann J. Uptake and translocation of inorganic and methylated arsenic species by plants. Environ. Chem. 2007, 4:197-203.
79. Rai A., Tripathi P., Dwivedi S., Dubey S., Shri M., Kumar S., Tripathi P.K., Dave R., Kumar A., Singh R., Adhikari B., Bag M., Tripathi R.D., Trivedi P.K., Chakrabarty D., Tuli R. Arsenic tolerances in rice (Oryza sativa) have a predominant role in transcriptional regulation of a set of genes including sulphur assimilation pathway and antioxidant system. Chemosphere 2011, 82:986-995.
80. Reichard J.F., Puga A. Effects of arsenic exposure on DNA methylation and epigenetic gene regulation. Epigenomics 2010, 2:87-104.
81. Reisinger S., Schiavon M., Terry N., Pilon-Smits E.A.H. Heavy metal tolerance and accumulation in Indian mustard (Brassica juncea L.) expressing bacterial γ-glutamylcysteine synthetase or glutathione synthetase. Int. J. Phytoremediation 2008, 10:440-454.
82. Requejo R., Tena M. Proteome analysis of maize roots reveals that oxidative stress is a main contributing factor to plant arsenic toxicity. Phytochemistry 2005, 66:1519-1528.
83. Requejo R., Tena M. Maize response to acute arsenic toxicity as revealed by proteome analysis of plant shoots. Proteomics 2006, 6:56-62.
84. Rodriguez-Gabriel M.A., Russell P. Distinct signaling pathways respond to arsenite and reactive oxygen species in Schizosaccharomyces pombe. Eukaryot. Cell 2005, 4:1396-1402.
85. Rosas-Castor J.M., Guzman-Mar J.L., Hernandez-Ramirez A., Garza-Gonzalez M.T., Hinojosa-Reyes L. Arsenic accumulation in maize crop (Zea mays): a review. Sci. Total Environ. 2014, 488:176-187.
86. Rosen B.P. Biochemistry of arsenic detoxification. FEBS Lett. 2002, 529:86-92.
87. Sánchez-Bermejo E., Castrillo G., del Llano B., Navarro C., Zarco-Fernández S., Martinez-Herrera D.J., Leo-del Puerto Y., Muñoz R., Cámara C., Paz-Ares J., Alonso-Blanco C., Leyva A. Nat. Commun. 2014, 5:4617.
88. Santra S.C., Samal A.C., Bhattacharya P., Banerjee S., Biswas A., Majumdar J. Arsenic in food chain and community health risk: a study in Gangetic West Bengal. Procedia Environ. Sci. 2013, 18:2-13.
89. Schmidt A.C., Reisser W., Mattusch J., Wennrich R., Jung K. Analysis of arsenic species accumulation by plants and the influence on their nitrogen uptake. J. Anal. At. Spectrom. 2004, 19:172-177.
90. Sebastian A., Prasad M.N.V. Cadmium minimization in rice. A review. Agron. Sustain. Dev. 2014, 34:155-173.
91. Shah D., Shen M.W.Y., Chen W., Da Silva N.A. Enhanced arsenic accumulation in Saccharomyces cerevisiae overexpressing transporters Fps1p or Hxt7p. J. Biotechnol. 2010, 150:101-107.
92. Shri M., Kumar S., Chakrabarty D., Trivedi P.K., Mallick S., Misra P., Shukla D., Mishra S., Srivastava S., Tripathi R.D., Tuli R. Effect of arsenic on growth, oxidative stress and antioxidant system in rice seedlings. Ecotoxicol. Environ. Saf. 2009, 72:1102-1110.
93. Shri M., Dave R., Dwivedi S., Shukla D., Kesari R., Tripathi R.D., Trivedi P.K., Chakrabarty D. Heterologous expression of Ceratophyllum demersum phytochelatin synthase, CdPCS1, in rice leads to lower arsenic accumulation in grain. Sci. Rep. 2014, 4:5784.
94. Shukla D., Kesari R., Mishra S., Dwivedi S., Tripathi R.D., Nath P., Trivedi P.K. Expression of phytochelatin synthase from aquatic macrophyte Ceratophyllum demersum L. enhances cadmium and arsenic accumulation in tobacco. Plant Cell Rep. 2012, 31:1687-1699.
95. Shukla D., Kesari R., Tiwari M., Dwivedi S., Tripathi R.D., Nath P., Trivedi P.K. Expression of Ceratophyllum demersum phytochelatin synthase, CdPCS1, in Escherichia coli and Arabidopsis enhances heavy metal(loid)s accumulation. Protoplasma 2013, 250:1263-1272.
96. Shukla D., Tiwari M., Tripathi R.D., Nath P., Trivedi P.K. Synthetic phytochelatins complement a phytochelatin-deficient Arabidopsis mutant and enhance the accumulation of heavy metal(loid)s. Biochem. Biophys. Res. Commun. 2013, 434:664-669.
97. Sinha D., Biswas J., Bishayee A. Nrf2-mediated redox signaling in arsenic carcinogenesis: a review. Arch. Toxicol. 2013, 87:383-396.
98. Song W.Y., Park J., Mendoza-Cozatl D.G., Suter-Grotemeyer M., Shim D., Hortensteiner S., Geisler M., Weder B., Rea P.A., Rentsch D., Schroeder J.I., Lee Y., Martinoia E. Arsenic tolerance in Arabidopsis is mediated by two ABCC-type phytochelatin transporters. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:21187-21192.
99. Sridokchan W., Markich S., Visoottiviseth P. Arsenic tolerance, accumulation and elemental distribution in twelve ferns: a screening study. Australas. J. Ecotoxicol. 2005, 11:101-110.
100. Srivastava S., Srivastava A.K., Suprasanna P., D'Souza S.F. Comparative biochemical and transcriptional profiling of two contrasting varieties of Brassica juncea L. in response to arsenic exposure reveals mechanisms of stress perception and tolerance. J. Exp. Bot. 2009, 60:3419-3431.
101. Srivastava S., Mishra S., Tripathi R.D., Dwivedi S., Trivedi P.K., Tandon P.K. Phytochelatins and antioxidant systems respond differentially during arsenite and arsenate stress in Hydrilla verticillata (L. f.) Royle. Environ. Sci. Technol. 2007, 41:2930-2936.
102. Srivastava S., Srivastava A.K., Suprasanna P., D'Souza S.F. Identification and profiling of arsenic stress-induced microRNAs in Brassica juncea. J. Exp. Bot. 2013, 64:303-315.
103. Su Y.H., McGrath S.P., Zhu Y.G., Zhao F.J. Highly efficient xylem transport of arsenite in the arsenic hyperaccumulator Pteris vittata. New Phytol. 2008, 180:434-441.
104. Su Y.H., McGrath S.P., Zhao F.J. Rice is more efficient in arsenite uptake and translocation than wheat and barley. Plant Soil 2010, 328:27-34.
105. Sundaram S., Wu S., Ma L.Q., Rathinasabapathi B. Expression of a Pteris vittata glutaredoxin PvGRX5 in transgenic Arabidopsis thaliana increases plant arsenic tolerance and decreases arsenic accumulation in the leaves. Plant Cell Environ. 2009, 32:851-858.
106. Takahashi Y., Minamikawa R., Hattori K.H., Kurishima K., Kihou N., Yuita K. Arsenic behavior in paddy fields during the cycle of flooded and non-flooded periods. Environ. Sci. Technol. 2004, 38:1038-1044.
107. Tiwari M., Sharma D., Dwivedi S., Singh M., Tripathi R.D., Trivedi P.K. Expression in Arabidopsis and cellular localization reveal involvement of rice NRAMP, OsNRAMP1, in arsenic transport and tolerance. Plant Cell Environ. 2014, 37:140-152.
108. Tripathi R.D., Srivastava S., Mishra S., Singh N., Tuli R. Arsenic hazards: strategies for tolerance and remediation by plants. Trends Biotechnol. 2007, 25:158-165.
109. Tripathi R.D., Tripathi P., Dwivedi S., Dubey S., Chatterjee S., Chakrabarty D., Trivedi P.K. Arsenomics: omics of arsenic metabolism in plants. Front. Physiol. 2012, 3:1-14.
110. Tuli R., Chakrabarty D., Trivedi P.K., Tripathi R.D. Recent advances in arsenic accumulation and metabolism in rice. Mol. Breed. 2010, 26:307-323.
111. Vahter M. Mechanisms of arsenic biotransformation. Toxicology 2002, 181:211-217.
112. Wangeline A.L., Burkhead J.L., Hale K.L., Lindblom S.D., Terry N., Pilon M., Pilon-Smits E.A. Overexpression of ATP sulfurylase in Indian mustard: effects on tolerance and accumulation of twelve metals. J. Environ. Qual. 2004, 33:54-60.
113. Williams P.N., Villada A., Deacon C., Raab A., Figuerola J., Green A.J., Feldmann J., Meharg A.A. Greatly enhanced arsenic shoot assimilation in rice leads to elevated grain levels compared to wheat and barley. Environ. Sci. Technol. 2007, 41:6854-6859.
114. Wilson S.C., Tighe M., Paterson E., Ashley P.M. Food crop accumulation and bioavailability assessment for antimony (Sb) compared with arsenic (As) in contaminated soils. Environ. Sci. Pollut. Res. 2014, 21:11671-11681.
115. Wojas S., Clemens S., Sklodowska A., Antosiewicz D. Arsenic response of AtPCS1- and CePCS-expressing plants - effects of external As(V) concentration on As-accumulation pattern and NPT metabolism. J. Plant Physiol. 2010, 167:169-175.
116. Wu Z., Ren H., McGrath S.P., Wu P., Zhao F.J. Investigating the contribution of the phosphate transport pathway to arsenic accumulation in rice. Plant Physiol. 2011, 157:498-508.
117. Wysocki R., Tamas M.J. Saccharomyces cerevisiae as a model organism for elucidating arsenic tolerance mechanisms. Cellular Effects of Heavy Metals 2011, 87-112.
118. Xu X.Y., McGrath S.P., Zhao F.J. Rapid reduction of arsenate in the medium mediated by plant roots. New Phytol. 2007, 176:590-599.
119. Xu X.Y., McGrath S.P., Meharg A.A., Zhao F.J. Growing rice aerobically markedly decreases arsenic accumulation. Environ. Sci. Technol. 2008, 42:5574-5579.
120. Xue P.Y., Yan C.Z. Arsenic accumulation and translocation in the submerged macrophyte Hydrilla verticillata (L.f.) Royle. Chemosphere 2011, 85:1176-1181.
121. Ye W.L., Wood B.A., Stroud J.L., Andralojc P.J., Raab A., McGrath S.P., Feldmann J., Zhao F.J. Arsenic speciation in phloem and xylem exudates of Castor Bean. Plant Physiol. 2010, 154:1505-1513.
122. Yu L.J., Luo Y.F., Liao B., Xie L.J., Chen L., Xiao S., Li J.T., Hu S.N., Shu W.S. Comparative transcriptome analysis of transporters, phytohormone and lipid metabolism pathways in response to arsenic stress in rice (Oryza sativa). New Phytol. 2012, 195:97-112.
123. Zhang W., Cai Y., Tu C., Ma L.Q. Arsenic speciation and distribution in an arsenic hyperaccumulating plant. Sci. Total Environ. 2002, 300:167-177.
124. Zhang W.D., Liu D.S., Tian J.C., He F.L. Toxicity and accumulation of arsenic in wheat (Triticum aestivum L.) varieties of China. Phyton Int. J. Exp. Bot. 2009, 78:147-154.
125. Zhao F.J., Dunham S.J., McGrath S.P. Arsenic hyperaccumulation by different fern species. New Phytol. 2002, 156:27-31.
126. Zhao F.J., Ma J.F., Meharg A.A., McGrath S.P. Arsenic uptake and metabolism in plants. New Phytol. 2009, 181:777-794.
127. Zhao F.J., McGrath S.P., Meharg A.A. Arsenic as a food chain contaminant: mechanisms of plant uptake and metabolism and mitigation strategies. Annu. Rev. Plant Biol. 2010, 61:535-559.
128. Zhao F.J., Zhu Y.G., Meharg A.A. Methylated arsenic species in rice: geographical variation, origin, and uptake mechanisms. Environ. Sci. Technol. 2013, 47:3957-3966.