P2Y2R activation by nucleotides released from the highly metastatic breast cancer cell contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment

Oncotarget

Volumn 5, Issue 19, 2014, Pages 9322-9334

  Joo, Young Nak ^a   Jin, Hana ^a   Eun, So Young ^a   Park, Sang Won ^a   Chang, Ki Churl ^a   Kim, Hye Jung ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

Author keywords

Collagen crosslinking; HIF 1a; LOX; Nucleotides; P2Y2R; Premetastatic niche formation

Indexed keywords

ADENOSINE TRIPHOSPHATE; CD11B ANTIGEN; COLLAGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NUCLEOTIDE; PROTEIN LYSINE 6 OXIDASE; PURINERGIC P2Y2 RECEPTOR; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; URIDINE TRIPHOSPHATE; CTRL PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; ITGAM PROTEIN, HUMAN; SERINE PROTEINASE;

ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DISTANT METASTASIS; ENDOTHELIUM CELL; ENVIRONMENTAL CHANGE; ENZYME RELEASE; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; MOLECULAR MECHANICS; MONOCYTE; MOUSE; NONHUMAN; PROTEIN CROSS LINKING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; TUMOR MICROENVIRONMENT; WESTERN BLOTTING; ZYMOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BREAST TUMOR; CANCER TRANSPLANTATION; CELL HYPOXIA; CELL MOTION; DISEASE COURSE; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MACROPHAGE; MCF 7 CELL LINE; METABOLISM; NUDE MOUSE; PATHOLOGY; RNA INTERFERENCE; SECRETION (PROCESS); TUMOR CELL LINE; TUMOR INVASION; XENOGRAFT;

ANIMALS; ANTIGENS, CD11B; BREAST NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; CELL MOVEMENT; COLLAGEN; DISEASE PROGRESSION; ENDOTHELIAL CELLS; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MACROPHAGES; MCF-7 CELLS; MICE; MICE, NUDE; MONOCYTES; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NUCLEOTIDES; PROTEIN-LYSINE 6-OXIDASE; RECEPTORS, PURINERGIC P2Y2; RNA INTERFERENCE; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES; TRANSPLANTATION, HETEROLOGOUS; TUMOR MICROENVIRONMENT;

EID: 84910031240     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: None     Document Type: Article

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