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Volumn 18, Issue 4, 2014, Pages

Silencing airway epithelial cell-derived hepcidin exacerbates sepsis-induced acute lung injury

Author keywords

[No Author keywords available]

Indexed keywords

FERROPORTIN; HEPCIDIN; INTERLEUKIN 6; IRON; MESSENGER RNA; SHORT HAIRPIN RNA;

EID: 84910026542     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-014-0470-8     Document Type: Article
Times cited : (31)

References (40)
  • 1
    • 84864742993 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • Matthay MA, Ware LB, Zimmerman GA. The acute respiratory distress syndrome. J Clin Invest 2012, 122:2731-2740. 10.1172/JCI60331, 22850883.
    • (2012) J Clin Invest , vol.122 , pp. 2731-2740
    • Matthay, M.A.1    Ware, L.B.2    Zimmerman, G.A.3
  • 2
    • 34548399925 scopus 로고    scopus 로고
    • Acute respiratory distress syndrome
    • Leaver SK, Evans TW. Acute respiratory distress syndrome. BMJ 2007, 335:389-394. 10.1136/bmj.39293.624699.AD, 17717368.
    • (2007) BMJ , vol.335 , pp. 389-394
    • Leaver, S.K.1    Evans, T.W.2
  • 3
    • 33847156932 scopus 로고    scopus 로고
    • Epidemiology and outcomes of acute lung injury
    • Rubenfeld GD, Herridge MS. Epidemiology and outcomes of acute lung injury. Chest 2007, 131:554-562. 10.1378/chest.06-1976, 17296661.
    • (2007) Chest , vol.131 , pp. 554-562
    • Rubenfeld, G.D.1    Herridge, M.S.2
  • 6
    • 43649105058 scopus 로고    scopus 로고
    • Mortality rates for patients with acute lung injury/ARDS have decreased over time
    • Zambon M, Vincent JL. Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest 2008, 133:1120-1127. 10.1378/chest.07-2134, 18263687.
    • (2008) Chest , vol.133 , pp. 1120-1127
    • Zambon, M.1    Vincent, J.L.2
  • 7
    • 74949124734 scopus 로고    scopus 로고
    • Human defensins and LL-37 in mucosal immunity
    • Doss M, White MR, Tecle T, Hartshorn KL. Human defensins and LL-37 in mucosal immunity. J Leukoc Biol 2010, 87:79-92. 10.1189/jlb.0609382, 19808939.
    • (2010) J Leukoc Biol , vol.87 , pp. 79-92
    • Doss, M.1    White, M.R.2    Tecle, T.3    Hartshorn, K.L.4
  • 8
    • 33645958888 scopus 로고    scopus 로고
    • Defensins and cathelicidins in inflammatory lung disease: beyond antimicrobial activity
    • Hiemstra PS. Defensins and cathelicidins in inflammatory lung disease: beyond antimicrobial activity. Biochem Soc Trans 2006, 34:276-278. 10.1042/BST20060276, 16545093.
    • (2006) Biochem Soc Trans , vol.34 , pp. 276-278
    • Hiemstra, P.S.1
  • 9
    • 12444337486 scopus 로고    scopus 로고
    • Expression and activity of beta-defensins and LL-37 in the developing human lung
    • Starner TD, Agerberth B, Gudmundsson GH, McCray PB. Expression and activity of beta-defensins and LL-37 in the developing human lung. J Immunol 2005, 174:1608-1615. 10.4049/jimmunol.174.3.1608, 15661923.
    • (2005) J Immunol , vol.174 , pp. 1608-1615
    • Starner, T.D.1    Agerberth, B.2    Gudmundsson, G.H.3    McCray, P.B.4
  • 10
    • 0036528903 scopus 로고    scopus 로고
    • Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection
    • Schaller-Bals S, Schulze A, Bals R. Increased levels of antimicrobial peptides in tracheal aspirates of newborn infants during infection. Am J Respir Crit Care Med 2002, 165:992-995. 10.1164/ajrccm.165.7.200110-020, 11934727.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 992-995
    • Schaller-Bals, S.1    Schulze, A.2    Bals, R.3
  • 11
    • 2942689531 scopus 로고    scopus 로고
    • High concentrations of alpha-defensins in plasma and bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome
    • Ashitani J, Mukae H, Arimura Y, Sano A, Tokojima M, Nakazato M. High concentrations of alpha-defensins in plasma and bronchoalveolar lavage fluid of patients with acute respiratory distress syndrome. Life Sci 2004, 75:1123-1134. 10.1016/j.lfs.2004.01.028, 15207659.
    • (2004) Life Sci , vol.75 , pp. 1123-1134
    • Ashitani, J.1    Mukae, H.2    Arimura, Y.3    Sano, A.4    Tokojima, M.5    Nakazato, M.6
  • 12
    • 33748748474 scopus 로고    scopus 로고
    • Protection against Pseudomonas aeruginosa pneumonia and sepsis-induced lung injury by overexpression of beta-defensin-2 in rats
    • Shu Q, Shi Z, Zhao Z, Chen Z, Yao H, Chen Q, Hoeft A, Stuber F, Fang X. Protection against Pseudomonas aeruginosa pneumonia and sepsis-induced lung injury by overexpression of beta-defensin-2 in rats. Shock 2006, 26:365-371. 10.1097/01.shk.0000224722.65929.58, 16980883.
    • (2006) Shock , vol.26 , pp. 365-371
    • Shu, Q.1    Shi, Z.2    Zhao, Z.3    Chen, Z.4    Yao, H.5    Chen, Q.6    Hoeft, A.7    Stuber, F.8    Fang, X.9
  • 13
    • 79955958017 scopus 로고    scopus 로고
    • Hepcidin and iron regulation, 10years later
    • Ganz T. Hepcidin and iron regulation, 10years later. Blood 2011, 117:4425-4433. 10.1182/blood-2011-01-258467, 21346250.
    • (2011) Blood , vol.117 , pp. 4425-4433
    • Ganz, T.1
  • 14
    • 45549096257 scopus 로고    scopus 로고
    • Fine tuning of hepcidin expression by positive and negative regulators
    • Muckenthaler MU. Fine tuning of hepcidin expression by positive and negative regulators. Cell Metab 2008, 8:1-3. 10.1016/j.cmet.2008.06.009, 18590684.
    • (2008) Cell Metab , vol.8 , pp. 1-3
    • Muckenthaler, M.U.1
  • 15
    • 78649634981 scopus 로고    scopus 로고
    • Hepcidin in human iron disorders: therapeutic implications
    • Pietrangelo A. Hepcidin in human iron disorders: therapeutic implications. J Hepatol 2011, 54:173-181. 10.1016/j.jhep.2010.08.004, 20932599.
    • (2011) J Hepatol , vol.54 , pp. 173-181
    • Pietrangelo, A.1
  • 17
    • 84868526205 scopus 로고    scopus 로고
    • Hepcidin and the iron-infection axis
    • Drakesmith H, Prentice AM. Hepcidin and the iron-infection axis. Science 2012, 338:768-772. 10.1126/science.1224577, 23139325.
    • (2012) Science , vol.338 , pp. 768-772
    • Drakesmith, H.1    Prentice, A.M.2
  • 18
    • 64049100955 scopus 로고    scopus 로고
    • Iron in innate immunity: starve the invaders
    • Ganz T. Iron in innate immunity: starve the invaders. Curr Opin Immunol 2009, 21:63-67. 10.1016/j.coi.2009.01.011, 19231148.
    • (2009) Curr Opin Immunol , vol.21 , pp. 63-67
    • Ganz, T.1
  • 19
    • 77954249308 scopus 로고    scopus 로고
    • Two to tango: regulation of mammalian iron metabolism
    • Hentze MW, Muckenthaler MU, Galy B, Camaschella C. Two to tango: regulation of mammalian iron metabolism. Cell 2010, 142:24-38. 10.1016/j.cell.2010.06.028, 20603012.
    • (2010) Cell , vol.142 , pp. 24-38
    • Hentze, M.W.1    Muckenthaler, M.U.2    Galy, B.3    Camaschella, C.4
  • 21
    • 84861184345 scopus 로고    scopus 로고
    • Hepcidin protects against lipopolysaccharide-induced liver injury in a mouse model of obstructive jaundice
    • Huang YH, Yang YL, Tiao MM, Kuo HC, Huang LT, Chuang JH. Hepcidin protects against lipopolysaccharide-induced liver injury in a mouse model of obstructive jaundice. Peptides 2012, 35:212-217. 10.1016/j.peptides.2012.03.032, 22504010.
    • (2012) Peptides , vol.35 , pp. 212-217
    • Huang, Y.H.1    Yang, Y.L.2    Tiao, M.M.3    Kuo, H.C.4    Huang, L.T.5    Chuang, J.H.6
  • 22
    • 79960891356 scopus 로고    scopus 로고
    • Hepcidin expression in human airway epithelial cells is regulated by interferon-γ
    • Frazier MD, Mamo LB, Ghio AJ, Turi JL. Hepcidin expression in human airway epithelial cells is regulated by interferon-γ. Respir Res 2011, 12:100. 10.1186/1465-9921-12-100, 21810240.
    • (2011) Respir Res , vol.12 , pp. 100
    • Frazier, M.D.1    Mamo, L.B.2    Ghio, A.J.3    Turi, J.L.4
  • 26
    • 84881121229 scopus 로고    scopus 로고
    • Triggering receptor expressed on myeloid cells-2 protects against polymicrobial sepsis by enhancing bacterial clearance
    • Chen Q, Zhang K, Jin Y, Zhu T, Cheng B, Shu Q, Fang X. Triggering receptor expressed on myeloid cells-2 protects against polymicrobial sepsis by enhancing bacterial clearance. Am J Respir Crit Care Med 2013, 188:201-212. 10.1164/rccm.201211-1967OC, 23721075.
    • (2013) Am J Respir Crit Care Med , vol.188 , pp. 201-212
    • Chen, Q.1    Zhang, K.2    Jin, Y.3    Zhu, T.4    Cheng, B.5    Shu, Q.6    Fang, X.7
  • 28
    • 2442658823 scopus 로고    scopus 로고
    • Hepatic iron concentration does not predict response to standard and pegylated-IFN/ribavirin therapy in patients with chronic hepatitis C
    • Hofer H, Osterreicher C, Jessner W, Penz M, Steindl-Munda P, Wrba F, Ferenci P. Hepatic iron concentration does not predict response to standard and pegylated-IFN/ribavirin therapy in patients with chronic hepatitis C. J Hepatol 2004, 40:1018-1022. 10.1016/j.jhep.2004.02.030, 15158344.
    • (2004) J Hepatol , vol.40 , pp. 1018-1022
    • Hofer, H.1    Osterreicher, C.2    Jessner, W.3    Penz, M.4    Steindl-Munda, P.5    Wrba, F.6    Ferenci, P.7
  • 29
    • 70350544115 scopus 로고    scopus 로고
    • Attenuation of IgG immune complex-induced acute lung injury by silencing C5aR in lung epithelial cells
    • Sun L, Guo RF, Gao H, Sarma JV, Zetoune FS, Ward PA. Attenuation of IgG immune complex-induced acute lung injury by silencing C5aR in lung epithelial cells. FASEB J 2009, 23:3808-3818. 10.1096/fj.09-133694, 19620403.
    • (2009) FASEB J , vol.23 , pp. 3808-3818
    • Sun, L.1    Guo, R.F.2    Gao, H.3    Sarma, J.V.4    Zetoune, F.S.5    Ward, P.A.6
  • 30
    • 20044385081 scopus 로고    scopus 로고
    • In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury
    • Lomas-Neira JL, Chung CS, Wesche DE, Perl M, Ayala A. In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury. J Leukoc Biol 2005, 77:846-853. 10.1189/jlb.1004617, 15695553.
    • (2005) J Leukoc Biol , vol.77 , pp. 846-853
    • Lomas-Neira, J.L.1    Chung, C.S.2    Wesche, D.E.3    Perl, M.4    Ayala, A.5
  • 31
    • 77952749839 scopus 로고    scopus 로고
    • Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-kappaB
    • Bao S, Liu MJ, Lee B, Besecker B, Lai JP, Guttridge DC, Knoell DL. Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-kappaB. Am J Physiol Lung Cell Mol Physiol 2010, 298:L744-L754. 10.1152/ajplung.00368.2009, 20207754.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , pp. L744-L754
    • Bao, S.1    Liu, M.J.2    Lee, B.3    Besecker, B.4    Lai, J.P.5    Guttridge, D.C.6    Knoell, D.L.7
  • 32
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004, 306:2090-2093. 10.1126/science.1104742, 15514116.
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.B.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 37
  • 40
    • 53149123286 scopus 로고    scopus 로고
    • Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation
    • Wang L, Johnson EE, Shi HN, Walker WA, Wessling-Resnick M, Cherayil BJ. Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation. J Immunol 2008, 181:2723-2731. 10.4049/jimmunol.181.4.2723, 18684963.
    • (2008) J Immunol , vol.181 , pp. 2723-2731
    • Wang, L.1    Johnson, E.E.2    Shi, H.N.3    Walker, W.A.4    Wessling-Resnick, M.5    Cherayil, B.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.