Omega-3 polyunsaturated fatty acids in large doses attenuate seizures, cognitive impairment, and hippocampal oxidative DNA damage in young kindled rats

Neuroscience Letters

Volumn 584, Issue , 2015, Pages 173-177

  Abdel Wahab, Basel A ^a   Al Qahtani, Jobran M ^b   El Safty, Samy A ^b  

^a Assiut University Faculty of Medicine   (Egypt)

^b NAJRAN UNIVERSITY   (Saudi Arabia)

Author keywords

DNA damage; Epilepsy and cognition; Omega 3; Oxidative stress; Passive avoidance; Pentylenetetrazole kindling

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; BIOLOGICAL MARKER; GLUTATHIONE; MALONALDEHYDE; OMEGA 3 FATTY ACID; PENTETRAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; ELEVATED PLUS MAZE TEST; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HIPPOCAMPUS; MALE; NONHUMAN; OXIDATIVE STRESS; PASSIVE AVOIDANCE; RAT; SEIZURE; ANIMAL; AVOIDANCE BEHAVIOR; COGNITION DISORDERS; DRUG EFFECTS; KINDLING; METABOLISM; PSYCHOLOGY; SEIZURES; WISTAR RAT;

ANIMALS; AVOIDANCE LEARNING; COGNITION DISORDERS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS, OMEGA-3; HIPPOCAMPUS; KINDLING, NEUROLOGIC; MALE; OXIDATIVE STRESS; RATS, WISTAR; SEIZURES;

EID: 84910026272     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.10.003     Document Type: Article

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